KEGG H.sapiens: 3945

Homo sapiens (human): 3945

Entry

3945 CDS H.sapiens

Gene name LDHB

Definition lactate dehydrogenase B (EC:1.1.1.27)

Orthology K00016 L-lactate dehydrogenase [EC:1.1.1.27]

Pathway hsa00010 Glycolysis / Gluconeogenesis
hsa00270 Cysteine and methionine metabolism
hsa00620 Pyruvate metabolism
hsa00640 Propanoate metabolism
hsa01100 Metabolic pathways

Class Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis
[PATH:hsa00010]
Metabolism; Carbohydrate Metabolism; Pyruvate metabolism
[PATH:hsa00620]
Metabolism; Carbohydrate Metabolism; Propanoate metabolism
[PATH:hsa00640]
Metabolism; Amino Acid Metabolism; Cysteine and methionine
metabolism [PATH:hsa00270]

SSDB

Motif Pfam: Ldh_1_N Ldh_1_C Glyco_hydro_4
PROSITE: L_LDH

Other DBs NCBI-GI: 4557032
NCBI-GeneID: 3945
OMIM: 150100
HGNC: 6541
HPRD: 01026
Ensembl: ENSG00000111716
UniProt: P07195 Q5U077

Structure

PDB: 1I0Z 1T2F

Position 12p12.2-p12.1

AA seq 334 aa
MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK
GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF
IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG
IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY
EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG
LTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL

NT seq 1005 nt +upstreamnt +downstreamnt
atggcaactcttaaggaaaaactcattgcaccagttgcggaagaagaggcaacagttcca
aacaataagatcactgtagtgggtgttggacaagttggtatggcgtgtgctatcagcatt
ctgggaaagtctctggctgatgaacttgctcttgtggatgttttggaagataagcttaaa
ggagaaatgatggatctgcagcatgggagcttatttcttcagacacctaaaattgtggca
gataaagattattctgtgaccgccaattctaagattgtagtggtaactgcaggagtccgt
cagcaagaaggggagagtcggctcaatctggtgcagagaaatgttaatgtcttcaaattc
attattcctcagatcgtcaagtacagtcctgattgcatcataattgtggtttccaaccca
gtggacattcttacgtatgttacctggaaactaagtggattacccaaacaccgcgtgatt
ggaagtggatgtaatctggattctgctagatttcgctaccttatggctgaaaaacttggc
attcatcccagcagctgccatggatggattttgggggaacatggcgactcaagtgtggct
gtgtggagtggtgtgaatgtggcaggtgtttctctccaggaattgaatccagaaatggga
actgacaatgatagtgaaaattggaaggaagtgcataagatggtggttgaaagtgcctat
gaagtcatcaagctaaaaggatataccaactgggctattggattaagtgtggctgatctt
attgaatccatgttgaaaaatctatccaggattcatcccgtgtcaacaatggtaaagggg
atgtatggcattgagaatgaagtcttcctgagccttccatgtatcctcaatgcccgggga
ttaaccagcgttatcaaccagaagctaaaggatgatgaggttgctcagctcaagaaaagt
gcagataccctgtgggacatccagaaggacctaaaagacctgtga

All links

Pathway (5)   
   KEGG PATHWAY (5)   
Disease (5)   
   KEGG DISEASE (4)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (6)   
   UniProt (2)   
   RefSeq(pep) (1)   
   IPI (3)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
3D Structure (2)   
   PDB (2)   
Protein domain (4)   
   Pfam (3)   
   PROSITE (1)   
All databases (46)

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