KEGG H.sapiens: 4128

Homo sapiens (human): 4128

Entry

4128 CDS H.sapiens

Gene name MAOA

Definition monoamine oxidase A (EC:1.4.3.4)

Orthology K00274 monoamine oxidase [EC:1.4.3.4]

Pathway hsa00260 Glycine, serine and threonine metabolism
hsa00330 Arginine and proline metabolism
hsa00340 Histidine metabolism
hsa00350 Tyrosine metabolism
hsa00360 Phenylalanine metabolism
hsa00380 Tryptophan metabolism
hsa00982 Drug metabolism - cytochrome P450
hsa01100 Metabolic pathways

Class Metabolism; Amino Acid Metabolism; Glycine, serine and threonine
metabolism [PATH:hsa00260]
Metabolism; Amino Acid Metabolism; Arginine and proline metabolism
[PATH:hsa00330]
Metabolism; Amino Acid Metabolism; Histidine metabolism
[PATH:hsa00340]
Metabolism; Amino Acid Metabolism; Tyrosine metabolism
[PATH:hsa00350]
Metabolism; Amino Acid Metabolism; Phenylalanine metabolism
[PATH:hsa00360]
Metabolism; Amino Acid Metabolism; Tryptophan metabolism
[PATH:hsa00380]
Metabolism; Xenobiotics Biodegradation and Metabolism; Drug
metabolism - cytochrome P450 [PATH:hsa00982]

SSDB

Motif Pfam: Amino_oxidase DAO FAD_binding_3 Pyr_redox HI0933_like
FAD_binding_2 Pyr_redox_2 Thi4 Lycopene_cycl GIDA AlaDh_PNT_C
M20_dimer 3HCDH_N TrkA_N Trp_halogenase
PROSITE: NLS_BP

Other DBs NCBI-GI: 4557735
NCBI-GeneID: 4128
OMIM: 309850
HGNC: 6833
HPRD: 02400
Ensembl: ENSG00000189221
UniProt: P21397 Q53YE7

Structure

PDB: 2Z5Y 2Z5X 2BXS 2BXR

Position Xp11.3

AA seq 527 aa
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS

NT seq 1584 nt +upstreamnt +downstreamnt
atggagaatcaagagaaggcgagtatcgcgggccacatgttcgacgtagtcgtgatcgga
ggtggcatttcaggactatctgctgccaaactcttgactgaatatggcgttagtgttttg
gttttagaagctcgggacagggttggaggaagaacatatactataaggaatgagcatgtt
gattacgtagatgttggtggagcttatgtgggaccaacccaaaacagaatcttacgcttg
tctaaggagctgggcatagagacttacaaagtgaatgtcagtgagcgtctcgttcaatat
gtcaaggggaaaacatatccatttcggggcgcctttccaccagtatggaatcccattgca
tatttggattacaataatctgtggaggacaatagataacatggggaaggagattccaact
gatgcaccctgggaggctcaacatgctgacaaatgggacaaaatgaccatgaaagagctc
attgacaaaatctgctggacaaagactgctaggcggtttgcttatctttttgtgaatatc
aatgtgacctctgagcctcacgaagtgtctgccctgtggttcttgtggtatgtgaagcag
tgcgggggcaccactcggatattctctgtcaccaatggtggccaggaacggaagtttgta
ggtggatctggtcaagtgagcgaacggataatggacctcctcggagaccaagtgaagctg
aaccatcctgtcactcacgttgaccagtcaagtgacaacatcatcatagagacgctgaac
catgaacattatgagtgcaaatacgtaattaatgcgatccctccgaccttgactgccaag
attcacttcagaccagagcttccagcagagagaaaccagttaattcagcggcttccaatg
ggagctgtcattaagtgcatgatgtattacaaggaggccttctggaagaagaaggattac
tgtggctgcatgatcattgaagatgaagatgctccaatttcaataaccttggatgacacc
aagccagatgggtcactgcctgccatcatgggcttcattcttgcccggaaagctgatcga
cttgctaagctacataaggaaataaggaagaagaaaatctgtgagctctatgccaaagtg
ctgggatcccaagaagctttacatccagtgcattatgaagagaagaactggtgtgaggag
cagtactctgggggctgctacacggcctacttccctcctgggatcatgactcaatatgga
agggtgattcgtcaacccgtgggcaggattttctttgcgggcacagagactgccacaaag
tggagcggctacatggaaggggcagttgaggctggagaacgagcagctagggaggtctta
aatggtctcgggaaggtgaccgagaaagatatctgggtacaagaacctgaatcaaaggac
gttccagcggtagaaatcacccacaccttctgggaaaggaacctgccctctgtttctggc
ctgctgaagatcattggattttccacatcagtaactgccctggggtttgtgctgtacaaa
tacaagctcctgccacggtcttga

All links

Pathway (8)   
   KEGG PATHWAY (8)   
Disease (1)   
   OMIM (1)   
Drug (11)   
   KEGG DRUG (11)   
Chemical substance (1)   
   KEGG COMPOUND (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (15)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (1)   
   IPI (1)   
DNA sequence (35)   
   RefSeq(nuc) (1)   
   GenBank (17)   
   EMBL (17)   
3D Structure (4)   
   PDB (4)   
Protein domain (16)   
   Pfam (15)   
   PROSITE (1)   
All databases (103)

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