KEGG H.sapiens: 4129

Homo sapiens (human): 4129

Entry

4129 CDS H.sapiens

Gene name MAOB

Definition monoamine oxidase B (EC:1.4.3.4)

Orthology K00274 monoamine oxidase [EC:1.4.3.4]

Pathway hsa00260 Glycine, serine and threonine metabolism
hsa00330 Arginine and proline metabolism
hsa00340 Histidine metabolism
hsa00350 Tyrosine metabolism
hsa00360 Phenylalanine metabolism
hsa00380 Tryptophan metabolism
hsa00982 Drug metabolism - cytochrome P450
hsa01100 Metabolic pathways

Class Metabolism; Amino Acid Metabolism; Glycine, serine and threonine
metabolism [PATH:hsa00260]
Metabolism; Amino Acid Metabolism; Arginine and proline metabolism
[PATH:hsa00330]
Metabolism; Amino Acid Metabolism; Histidine metabolism
[PATH:hsa00340]
Metabolism; Amino Acid Metabolism; Tyrosine metabolism
[PATH:hsa00350]
Metabolism; Amino Acid Metabolism; Phenylalanine metabolism
[PATH:hsa00360]
Metabolism; Amino Acid Metabolism; Tryptophan metabolism
[PATH:hsa00380]
Metabolism; Xenobiotics Biodegradation and Metabolism; Drug
metabolism - cytochrome P450 [PATH:hsa00982]

SSDB

Motif Pfam: Amino_oxidase DAO FAD_binding_2 Thi4 FAD_binding_3 Pyr_redox
Pyr_redox_2 HI0933_like GIDA Lycopene_cycl IlvN AlaDh_PNT_C
TrkA_N 3HCDH_N Trp_halogenase

Other DBs NCBI-GI: 38202207
NCBI-GeneID: 4129
OMIM: 309860
HGNC: 6834
HPRD: 02401
Ensembl: ENSG00000069535
UniProt: P27338

Structure

PDB: 1S3E 1S3B 2BK5 2C70 1S2Q 1S2Y 2C64 2VZ2
     2VRL 2VRM 2V61 2V5Z 2V60 2C72 2C73 2C75
     2C76 2C65 2C66 2C67 2BYB 2BK3 2BK4 1OJ9
     1OJA 1OJB 1OJC 1OJD 1GOS

Position Xp11.23

AA seq 520 aa
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV

NT seq 1563 nt +upstreamnt +downstreamnt
atgagcaacaaatgcgacgtggtcgtggtggggggcggcatctcaggtatggcagcagcc
aaacttctgcatgactctggactgaatgtggttgttctggaagcccgggaccgtgtggga
ggcaggacttacactcttaggaaccaaaaggttaaatatgtggaccttggaggatcctat
gttggaccaacccagaatcgtatcttgagattagccaaggagctaggattggagacctac
aaagtgaatgaggttgagcgtctgatccaccatgtaaagggcaaatcataccccttcagg
gggccattcccacctgtatggaatccaattacctacttagatcataacaacttttggagg
acaatggatgacatggggcgagagattccgagtgatgccccatggaaggctccccttgca
gaagagtgggacaacatgacaatgaaggagctactggacaagctctgctggactgaatct
gcaaagcagcttgccactctctttgtgaacctgtgtgtcactgcagagacccatgaggtc
tctgctctctggttcctgtggtatgtgaagcagtgtggaggcacaacaagaatcatctcg
acaacaaatggaggacaggagaggaaatttgtgggcggatctggtcaagtgagtgagcgg
ataatggacctccttggagaccgagtgaagctggagaggcctgtgatctacattgaccag
acaagagaaaatgtccttgtggagaccctaaaccatgagatgtatgaggctaaatatgtg
attagtgctattcctcctactctgggcatgaagattcacttcaatccccctctgccaatg
atgagaaaccagatgatcactcgtgtgcctttgggttcagtcatcaagtgtatagtttat
tataaagagcctttctggaggaaaaaggattactgtggaaccatgattattgatggagaa
gaagctccagttgcctacacgttggatgataccaaacctgaaggcaactatgctgccata
atgggatttatcctggcccacaaagccagaaaactggcacgtcttaccaaagaggaaagg
ttgaagaaactttgtgaactctatgccaaggttctgggttccctagaagctctggagcca
gtgcattatgaagaaaagaactggtgtgaggagcagtactctgggggctgctacacaact
tatttcccccctgggatcctgactcaatatggaagggttctacgccagccagtggacagg
atttactttgcaggcaccgagactgccacacactggagcggctacatggagggggctgta
gaggccggggagagagcagcccgagagatcctgcatgccatggggaagattccagaggat
gaaatctggcagtcagaaccagagtctgtggatgtccctgcacagcccatcaccaccacc
tttttggagagacatttgccctccgtgccaggcctgctcaggctgattggattgaccacc
atcttttcagcaacggctcttggcttcctggcccacaaaagggggctacttgtgagagtc
taa

All links

Pathway (8)   
   KEGG PATHWAY (8)   
Disease (1)   
   OMIM (1)   
Drug (11)   
   KEGG DRUG (11)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
3D Structure (29)   
   PDB (29)   
Protein domain (15)   
   Pfam (15)   
All databases (97)

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