KEGG   Homo sapiens (human): 4191Help
Entry
4191              CDS       H.sapiens                              
Gene name MDH2
Definition malate dehydrogenase 2, NAD (mitochondrial) (EC:1.1.1.37)
Orthology K00026  malate dehydrogenase [EC:1.1.1.37]
Pathway hsa00020  Citrate cycle (TCA cycle)
hsa00620  Pyruvate metabolism
hsa00630  Glyoxylate and dicarboxylate metabolism
hsa01100  Metabolic pathways
Class Metabolism; Carbohydrate Metabolism; Citrate cycle (TCA cycle)
[PATH:hsa00020]
Metabolism; Carbohydrate Metabolism; Pyruvate metabolism
[PATH:hsa00620]
Metabolism; Carbohydrate Metabolism; Glyoxylate and dicarboxylate
metabolism [PATH:hsa00630]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: Ldh_1_C Ldh_1_N Semialdhyde_dh 3Beta_HSD THF_DHG_CYH_C DapB_N
      FIST
PROSITE: MDH
Motif
Other DBs NCBI-GI: 21735621
NCBI-GeneID: 4191
OMIM: 154100
HGNC: 6971
HPRD: 01099
Ensembl: ENSG00000146701
UniProt: P40926
Structure
PDB: 2DFD
     Thumbnails

Jmol
Position 7cen-q22
AA seq 338 aa AA seqDB search
MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI
VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF
VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA
KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE
KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
NT seq 1017 nt NT seq  +upstreamnt  +downstreamnt
atgctctccgccctcgcccggcctgccagcgctgctctccgccgcagcttcagcacctcg
gcccagaacaatgctaaagtagctgtgctaggggcctctggaggcatcgggcagccactt
tcacttctcctgaagaacagccccttggtgagccgcctgaccctctatgatatcgcgcac
acacccggagtggccgcagatctgagccacatcgagaccaaagccgctgtgaaaggctac
ctcggacctgaacagctgcctgactgcctgaaaggttgtgatgtggtagttattccggct
ggagtccccagaaagccaggcatgacccgggacgacctgttcaacaccaatgccacgatt
gtggccaccctgaccgctgcctgtgcccagcactgcccggaagccatgatctgcgtcatt
gccaatccggttaattccaccatccccatcacagcagaagttttcaagaagcatggagtg
tacaaccccaacaaaatcttcggcgtgacgaccctggacatcgtcagagccaacaccttt
gttgcagagctgaagggtttggatccagctcgagtcaacgtccctgtcattggtggccat
gctgggaagaccatcatccccctgatctctcagtgcacccccaaggtggactttccccag
gaccagctgacagcactcactgggcggatccaggaggccggcacggaggtggtcaaggct
aaagccggagcaggctctgccaccctctccatggcgtatgccggcgcccgctttgtcttc
tcccttgtggatgcaatgaatggaaaggaaggtgttgtggaatgttccttcgttaagtca
caggaaacggaatgtacctacttctccacaccgctgctgcttgggaaaaagggcatcgag
aagaacctgggcatcggcaaagtctcctcttttgaggagaagatgatctcggatgccatc
cccgagctgaaggcctccatcaagaagggggaagatttcgtgaagaccctgaagtga
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