KEGG H.sapiens: 440

Homo sapiens (human): 440

Entry

440 CDS H.sapiens

Gene name ASNS

Definition asparagine synthetase (EC:6.3.5.4)

Orthology K01953 asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]

Pathway hsa00250 Alanine, aspartate and glutamate metabolism
hsa00910 Nitrogen metabolism
hsa01100 Metabolic pathways

Class Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:hsa00910]
Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate
metabolism [PATH:hsa00250]

SSDB

Motif Pfam: Asn_synthase GATase_2 tRNA_Me_trans ExsB NAD_synthase
PROSITE: GATASE_TYPE_2

Other DBs NCBI-GI: 168229250
NCBI-GeneID: 440
OMIM: 108370
HGNC: 753
HPRD: 00153
Ensembl: ENSG00000070669
UniProt: P08243

Position 7q21.3

AA seq 561 aa
MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQ
PIRVKKYPYLWLCYNGEIYNHKKMQQHFEFEYQTKVDGEIILHLYDKGGIEQTICMLDGV
FAFVLLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVTLKHSATPFLKVEPF
LPGHYEVLDLKPNGKVASVEMVKYHHCRDVPLHALYDNVEKLFPGFEIETVKNNLRILFN
NAVKKRLMTDRRIGCLLSGGLDSSLVAATLLKQLKEAQVQYPLQTFAIGMEDSPDLLAAR
KVADHIGSEHYEVLFNSEEGIQALDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVV
IFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLRELYLFDVLRADRTTAAHGLELRVPF
LDHRFSSYYLSLPPEMRIPKNGIEKHLLRETFEDSNLIPKEILWRPKEAFSDGITSVKNS
WFKILQEYVEHQVDDAMMANAAQKFPFNTPKTKEGYYYRQVFERHYPGRADWLSHYWMPK
WINATDPSARTLTHYKSAVKA

NT seq 1686 nt +upstreamnt +downstreamnt
atgtgtggcatttgggcgctgtttggcagtgatgattgcctttctgttcagtgtctgagt
gctatgaagattgcacacagaggtccagatgcattccgttttgagaatgtcaatggatac
accaactgctgctttggatttcaccggttggcggtagttgacccgctgtttggaatgcag
ccaattcgagtgaagaaatatccgtatttgtggctctgttacaatggtgaaatctacaac
cataagaagatgcaacagcattttgaatttgaataccagaccaaagtggatggtgagata
atccttcatctttatgacaaaggaggaattgagcaaacaatttgtatgttggatggtgtg
tttgcatttgttttactggatactgccaataagaaagtgttcctgggtagagatacatat
ggagtcagacctttgtttaaagcaatgacagaagatggatttttggctgtatgttcagaa
gctaaaggtcttgttacattgaagcactccgcgactccctttttaaaagtggagcctttt
cttcctggacactatgaagttttggatttaaagccaaatggcaaagttgcatccgtggaa
atggttaaatatcatcactgtcgggatgtacccctgcacgccctctatgacaatgtggag
aaactctttccaggttttgagatagaaactgtgaagaacaacctcaggatcctttttaat
aatgctgtaaagaaacgtttgatgacagacagaaggattggctgccttttatcagggggc
ttggactccagcttggttgctgccactctgttgaagcagctgaaagaagcccaagtacag
tatcctctccagacatttgcaattggcatggaagacagccccgatttactggctgctaga
aaggtggcagatcatattggaagtgaacattatgaagtcctttttaactctgaggaaggc
attcaggctctggatgaagtcatattttccttggaaacttatgacattacaacagttcgt
gcttcagtaggtatgtatttaatttccaagtatattcggaagaacacagatagcgtggtg
atcttctctggagaaggatcagatgaacttacgcagggttacatatattttcacaaggct
ccttctcctgaaaaagccgaggaggagagtgagaggcttctgagggaactctatttgttt
gatgttctccgcgcagatcgaactactgctgcccatggtcttgaactgagagtcccattt
ctagatcatcgattttcttcctattacttgtctctgccaccagaaatgagaattccaaag
aatgggatagaaaaacatctcctgagagagacgtttgaggattccaatctgatacccaaa
gagattctctggcgaccaaaagaagccttcagtgatggaataacttcagttaagaattcc
tggtttaagattttacaggaatacgttgaacatcaggttgatgatgcaatgatggcaaat
gcagcccagaaatttcccttcaatactcctaaaaccaaagaaggatattactaccgtcaa
gtctttgaacgccattacccaggccgggctgactggctgagccattactggatgcccaag
tggatcaatgccactgacccttctgcccgcacgctgacccactacaagtcagctgtcaaa
gcttag

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (10)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (14)   
   UniProt (1)   
   RefSeq(pep) (3)   
   IPI (10)   
DNA sequence (15)   
   RefSeq(nuc) (3)   
   GenBank (6)   
   EMBL (6)   
Protein domain (6)   
   Pfam (5)   
   PROSITE (1)   
All databases (57)

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