KEGG   Homo sapiens (human): 462Help
Entry
462               CDS       T01001                                 

Gene name
SERPINC1, AT3, AT3D, ATIII, THPH7
Definition
serpin peptidase inhibitor, clade C (antithrombin), member 1
Orthology
K03911  
antithrombin III
Organism
hsa  Homo sapiens (human)
Pathway
Complement and coagulation cascades
Disease
H00223  
Inherited thrombophilia
H01381  
Antithrombin III deficiency
Drug target
Heparin: 
Dalteparin: 
Enoxaparin: 
Parnaparin: 
Reviparin: 
Danaparoid: 
Tinzaparin: 
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Organismal Systems
  Immune system
   04610 Complement and coagulation cascades
    462 (SERPINC1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   462 (SERPINC1)
Heparan sulfate/heparin binding proteins [BR:hsa00536]
 Coagulation and fibrinolysis (General comment) Coagulation, inflammation, complement control
  462 (SERPINC1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
1q25.1
AA seq 464 aa AA seqDB search
MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEK
KATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFA
MTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFG
DKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAIN
ELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQ
VLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDG
FSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAV
VIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
NT seq 1395 nt NT seq  +upstreamnt  +downstreamnt
atgtattccaatgtgataggaactgtaacctctggaaaaaggaaggtttatcttttgtcc
ttgctgctcattggcttctgggactgcgtgacctgtcacgggagccctgtggacatctgc
acagccaagccgcgggacattcccatgaatcccatgtgcatttaccgctccccggagaag
aaggcaactgaggatgagggctcagaacagaagatcccggaggccaccaaccggcgtgtc
tgggaactgtccaaggccaattcccgctttgctaccactttctatcagcacctggcagat
tccaagaatgacaatgataacattttcctgtcacccctgagtatctccacggcttttgct
atgaccaagctgggtgcctgtaatgacaccctccagcaactgatggaggtatttaagttt
gacaccatatctgagaaaacatctgatcagatccacttcttctttgccaaactgaactgc
cgactctatcgaaaagccaacaaatcctccaagttagtatcagccaatcgcctttttgga
gacaaatcccttaccttcaatgagacctaccaggacatcagtgagttggtatatggagcc
aagctccagcccctggacttcaaggaaaatgcagagcaatccagagcggccatcaacaaa
tgggtgtccaataagaccgaaggccgaatcaccgatgtcattccctcggaagccatcaat
gagctcactgttctggtgctggttaacaccatttacttcaagggcctgtggaagtcaaag
ttcagccctgagaacacaaggaaggaactgttctacaaggctgatggagagtcgtgttca
gcatctatgatgtaccaggaaggcaagttccgttatcggcgcgtggctgaaggcacccag
gtgcttgagttgcccttcaaaggtgatgacatcaccatggtcctcatcttgcccaagcct
gagaagagcctggccaaggtagagaaggaactcaccccagaggtgctgcaagagtggctg
gatgaattggaggagatgatgctggtggtccacatgccccgcttccgcattgaggacggc
ttcagtttgaaggagcagctgcaagacatgggccttgtcgatctgttcagccctgaaaag
tccaaactcccaggtattgttgcagaaggccgagatgacctctatgtctcagatgcattc
cataaggcatttcttgaggtaaatgaagaaggcagtgaagcagctgcaagtaccgctgtt
gtgattgctggccgttcgctaaaccccaacagggtgactttcaaggccaacaggcctttc
ctggtttttataagagaagttcctctgaacactattatcttcatgggcagagtagccaac
ccttgtgttaagtaa

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