KEGG H.sapiens: 50

Homo sapiens (human): 50

Entry

50 CDS H.sapiens

Gene name ACO2

Definition aconitase 2, mitochondrial (EC:4.2.1.3)

Orthology K01681 aconitate hydratase 1 [EC:4.2.1.3]

Pathway hsa00020 Citrate cycle (TCA cycle)
hsa00630 Glyoxylate and dicarboxylate metabolism
hsa01100 Metabolic pathways

Class Metabolism; Carbohydrate Metabolism; Citrate cycle (TCA cycle)
[PATH:hsa00020]
Metabolism; Carbohydrate Metabolism; Glyoxylate and dicarboxylate
metabolism [PATH:hsa00630]

SSDB

Motif Pfam: Aconitase Aconitase_C
PROSITE: ACONITASE_2 THIOLASE_3 ACONITASE_1

Other DBs NCBI-GI: 4501867
NCBI-GeneID: 50
OMIM: 100850
HGNC: 118
HPRD: 00012
Ensembl: ENSG00000100412
UniProt: Q99798

Position 22q11.2-q13.31; 22q13.2

AA seq 780 aa
MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIHYDLLEKNINIVRKRLN
RPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAV
PSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILEN
YAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSG
WSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYN
HRMKKYLSKTGREDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTPDLAHP
VAEVGKVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGS
EQIRATIERDGYAQILRDLGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRN
DANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTDGKKFRLEAPDADELPKGEFDPG
QDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAA
GPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVI
GDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHP
VDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ

NT seq 2343 nt +upstreamnt +downstreamnt
atggcgccctacagcctactggtgactcggctgcagaaagctctgggtgtgcggcagtac
catgtggcctcagtcctgtgccaacgggccaaggtggcgatgagccactttgagcccaac
gagtacatccattatgacctgctagagaagaacattaacattgttcgcaaacgactgaac
cggccgctgacactctcggagaagattgtgtatggacacctggatgaccccgccagccag
gaaattgagcgaggcaagtcgtacctgcggctgcggccggaccgtgtggccatgcaggat
gcgacggcccagatggccatgctccagttcatcagcagcgggctgtccaaggtggctgtg
ccatccaccatccactgtgaccatctgattgaagcccaggttgggggcgagaaagacctg
cgccgggccaaggacatcaaccaggaagtttataatttcctggcaactgcaggtgccaaa
tatggcgtgggcttctggaagcctggatctggaatcattcaccagattattctggaaaac
tatgcgtaccctggtgttcttctgattggcactgactcccacacccccaatggtggcggc
cttgggggcatctgcattggagttgggggtgccgatgctgtggatgtcatggctgggatc
ccctgggagctgaagtgccccaaggtgattggcgtgaagctgacgggctctctctccggt
tggtcctcacccaaagatgtgatcctgaaggtggcaggcatcctcacggtgaaaggtggc
acaggtgcaatcgtggaataccacgggcctggtgtagactccatctcctgcactggcatg
gcgacaatctgcaacatgggtgcagaaattggggccaccacttccgtgttcccttacaac
cacaggatgaagaagtacctgagcaagaccggccgggaagacattgccaatctagctgat
gaattcaaggatcacttggtgcctgaccctggctgccattatgaccaactaattgaaatt
aacctcagtgagctgaagccacacatcaatgggcccttcacccctgacctggctcaccct
gtggcagaagtgggcaaggtggcagagaaggaaggatggcctctggacatccgagtgggt
ctaattggtagctgcaccaattcaagctatgaagatatggggcgctcagcagctgtggcc
aagcaggcactggcccatggcctcaagtgcaagtcccagttcaccatcactccaggttcc
gagcagatccgcgccaccattgagcgggacggctatgcacagatcttgagggatctgggt
ggcattgtcctggccaatgcttgtggcccctgcattggccagtgggacaggaaggacatc
aagaagggggagaagaacacaatcgtcacctcctacaacaggaacttcacgggccgcaac
gacgcaaaccccgagacccatgcctttgtcacgtccccagagattgtcacagccctggcc
attgcgggaaccctcaagttcaacccagagaccgactacctgacgggcacggatggcaag
aagttcaggctggaggctccggatgcagatgagcttcccaaaggggagtttgacccaggg
caggacacctaccagcacccacccaaggacagcagcgggcagcatgtggacgtgagcccc
accagccagcgcctgcagctcctggagccttttgacaagtgggatggcaaggacctggag
gacctgcagatcctcatcaaggtcaaagggaagtgtaccactgaccacatctcagctgct
ggcccctggctcaagttccgtgggcacttggataacatctccaacaacctgctcattggt
gccatcaacattgaaaacggcaaggccaactccgtgcgcaatgccgtcactcaggagttt
ggccccgtccctgacactgcccgctactacaagaaacatggcatcaggtgggtggtgatc
ggagacgagaactacggcgagggctcgagccgggagcatgcagctctggagcctcgccac
cttgggggccgggccatcatcaccaagagctttgccaggatccacgagaccaacctgaag
aaacagggcctgctgcctctgaccttcgctgacccggctgactacaacaagattcaccct
gtggacaagctgaccattcagggcctgaaggacttcacccctggcaagcccctgaagtgc
atcatcaagcaccccaacgggacccaggagaccatcctcctgaaccacaccttcaacgag
acgcagattgagtggttccgcgctggcagtgccctcaacagaatgaaggaactgcaacag
tga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (4)   
DNA sequence (37)   
   RefSeq(nuc) (1)   
   GenBank (18)   
   EMBL (18)   
Protein domain (5)   
   Pfam (2)   
   PROSITE (3)   
All databases (67)

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