KEGG   Homo sapiens (human): 50487Help
Entry
50487             CDS       H.sapiens                              
Gene name PLA2G3
Definition phospholipase A2, group III (EC:3.1.1.4)
Orthology K01047  phospholipase A2 [EC:3.1.1.4]
Pathway hsa00564  Glycerophospholipid metabolism
hsa00565  Ether lipid metabolism
hsa00590  Arachidonic acid metabolism
hsa00591  Linoleic acid metabolism
hsa00592  alpha-Linolenic acid metabolism
hsa01100  Metabolic pathways
hsa04010  MAPK signaling pathway
hsa04270  Vascular smooth muscle contraction
hsa04370  VEGF signaling pathway
hsa04664  Fc epsilon RI signaling pathway
hsa04730  Long-term depression
hsa04912  GnRH signaling pathway
Class Metabolism; Lipid Metabolism; Glycerophospholipid metabolism
[PATH:hsa00564]
Metabolism; Lipid Metabolism; Ether lipid metabolism [PATH:hsa00565]
Metabolism; Lipid Metabolism; Arachidonic acid metabolism
[PATH:hsa00590]
Metabolism; Lipid Metabolism; Linoleic acid metabolism
[PATH:hsa00591]
Metabolism; Lipid Metabolism; alpha-Linolenic acid metabolism
[PATH:hsa00592]
Environmental Information Processing; Signal Transduction; MAPK
signaling pathway [PATH:hsa04010]
Environmental Information Processing; Signal Transduction; VEGF
signaling pathway [PATH:hsa04370]
Organismal Systems; Immune System; Fc epsilon RI signaling pathway
[PATH:hsa04664]
Organismal Systems; Endocrine System; GnRH signaling pathway
[PATH:hsa04912]
Organismal Systems; Circulatory System; Vascular smooth muscle
contraction [PATH:hsa04270]
Organismal Systems; Nervous System; Long-term depression
[PATH:hsa04730]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: Phospholip_A2_2 Acetate_kinase
PROSITE: PA2_HIS
Motif
Other DBs NCBI-GI: 142976884
NCBI-GeneID: 50487
OMIM: 611651
HGNC: 17934
HPRD: 07144
Ensembl: ENSG00000100078
UniProt: Q9NZ20
Position 22q11.2-q13.2
AA seq 509 aa AA seqDB search
MGVQAGLFGMLGFLGVALGGSPALRWYRTSCHLTKAVPGNPLGYLSFLAKDAQGLALIHA
RWDAHRRLQSCSWEDEPELTAAYGALCAHETAWGSFIHTPGPELQRALATLQSQWEACRA
LEESPAGARKKRAAGQSGVPGGGHQREKRGWTMPGTLWCGVGDSAGNSSELGVFQGPDLC
CREHDRCPQNISPLQYNYGIRNYRFHTISHCDCDTRFQQCLQNQHDSISDIVGVAFFNVL
EIPCFVLEEQEACVAWYWWGGCRMYGTVPLARLQPRTFYNASWSSRATSPTPSSRSPAPP
KPRQKQHLRKGPPHQKGSKRPSKANTTALQDPMVSPRLDVAPTGLQGPQGGLKPQGARWV
CRSFRRHLDQCEHQIGPREIEFQLLNSAQEPLFHCNCTRRLARFLRLHSPPEVTNMLWEL
LGTTCFKLAPPLDCVEGKNCSRDPRAIRVSARHLRRLQQRRHQLQDKGTDERQPWPSEPL
RGPMSFYNQCLQLTQAARRPDRQQKSWSQ
NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt
atgggggttcaggcagggctgtttgggatgctgggcttcctgggggtggccctggggggc
tcccctgccctccgctggtacaggacctcctgccacttgaccaaggccgtccctggcaac
ccactggggtacctgagcttcctggccaaggatgctcagggactggccctgatccatgcc
cgctgggatgcgcataggaggctgcagtcatgtagctgggaggatgagccggagctcacc
gcagcctacggtgctctctgtgctcatgagactgcctggggctccttcatccacaccccc
ggacccgagctgcagagagcactggccactcttcagagtcagtgggaggcatgccgagcg
cttgaggagagtccagcaggggccaggaagaagcgagcagcagggcagagtggagtccct
ggtggagggcaccagcgagagaagagaggatggaccatgcctggcacactgtggtgtgga
gttggagattctgctgggaactcctcggagctgggggtcttccagggacctgatctctgt
tgccgggaacatgaccgctgcccacagaacatctcacccttgcagtacaactatggcatc
cgaaactaccgattccacaccatctcccactgtgactgtgacaccaggtttcagcaatgc
ctacagaatcagcacgactccatctcggacatcgtgggcgtggccttcttcaacgtgctg
gagatcccctgctttgtgctggaggagcaggaggcgtgtgtggcgtggtactggtggggc
gggtgtaggatgtacggcacagtgcccctcgctcgcctgcagcccaggaccttctacaat
gcctcctggagctcccgggccacctccccaactcccagctcccggagcccagcccctccc
aagcctcgacagaagcagcaccttcggaaggggccaccacatcagaaagggtccaagcgc
cccagcaaagccaacaccacagccctccaggaccctatggtctctcccaggcttgatgtg
gcccccacaggcctccagggcccacagggtggcctaaaacctcagggtgcccgctgggtc
tgccgcagcttccgccgccacctggaccagtgtgagcaccagattgggccccgggaaatc
gagttccagctgctcaacagcgcccaagagcccctcttccactgcaactgcacgcgccgt
ctggcacgcttcctgaggctccacagcccacccgaggttaccaacatgctttgggagctg
ctgggcacaacctgcttcaagctggcccctccactggactgtgtggaaggcaaaaactgt
tccagagaccctagggccatcagggtgtcagcccggcacttgcggaggcttcagcagagg
cgacaccagctccaggataaaggcacagatgagaggcagccatggccttcagagcccctg
agaggccccatgtcattctacaaccagtgcctgcagctaacccaggcagccaggagaccc
gacaggcagcagaagtcctggagccagtga
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