KEGG H.sapiens: 5207

Homo sapiens (human): 5207

Entry

5207 CDS H.sapiens

Gene name PFKFB1

Definition 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (EC:2.7.1.105
3.1.3.46)

Orthology K00900 6-phosphofructo-2-kinase [EC:2.7.1.105]
K01103 fructose-2,6-bisphosphatase [EC:3.1.3.46]

Pathway hsa00051 Fructose and mannose metabolism

Class Metabolism; Carbohydrate Metabolism; Fructose and mannose metabolism
[PATH:hsa00051]

SSDB

Motif Pfam: 6PF2K PGAM Zeta_toxin KTI12 Arf
PROSITE: PG_MUTASE

Other DBs NCBI-GI: 118582286
NCBI-GeneID: 5207
OMIM: 311790
HGNC: 8872
HPRD: 02411
Ensembl: ENSG00000158571
UniProt: P16118

Structure

PDB: 1K6M

Position Xp11.21

AA seq 471 aa
MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYIST
KLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKDVHNYL
SHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPD
YIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRT
VYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLK
VWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY
RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLH
TVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY

NT seq 1416 nt +upstreamnt +downstreamnt
atgtctccagagatgggagagctcacccaaaccaggttgcagaagatctggattccacac
agcagcggcagcagcaggctgcaacggagaaggggctcatccataccccagtttaccaat
tcccccacaatggtgatcatggtgggtttaccagctcgaggcaagacctatatctccaca
aagctcacacgatatctcaactggataggaacaccaactaaagtgtttaatttaggccag
tatcgacgagaggcagtgagctacaagaactatgaattctttcttccagacaacatggaa
gccctgcaaatcaggaagcagtgcgccctggcagccctgaaggatgttcacaactatctc
agccatgaggaaggtcatgttgcggtttttgatgccaccaacactaccagagaacgacgg
tcactgatcctgcagtttgcaaaagaacatggttacaaggtgtttttcattgagtccatt
tgtaatgaccctggcataattgcagaaaacatcaggcaagtgaaacttggcagccctgat
tatatagactgtgaccgggaaaaggttctggaagactttctaaagagaattgagtgctat
gaggtcaactaccaacccttggatgaggaactggacagccacctgtcctacatcaagatc
ttcgacgtgggcacacgctacatggtgaaccgagtgcaggatcacatccagagccgcaca
gtctactacctcatgaatatccatgtcacacctcgctccatctacctttgccgacatggc
gagagtgaactcaacatcagaggccgcatcggaggtgactctggcctctcagttcgcggc
aagcagtatgcctatgccctggccaacttcattcagtcccagggcatcagctccctgaag
gtgtggaccagtcacatgaagaggaccatccagacagctgaggccctgggtgtcccctat
gagcagtggaaggccctgaatgagattgatgcgggtgtctgtgaggagatgacctatgaa
gaaatccaggaacattaccctgaagaatttgcactgcgagaccaagataaatatcgctac
cgctatcccaagggagagtcctatgaggatctggttcagcgtctggagccagtgataatg
gagctagaacgacaggagaatgtactggtgatctgccaccaggctgtcatgcggtgcctc
ctggcctatttcctggataaaagttcagatgagcttccatatctcaagtgccctctgcac
acagtgctcaaactcactcctgtggcttatggctgcaaagtggaatccatctacctgaat
gtggaggccgtgaacacacaccgggagaagcctgagaatgtggacatcacccgggaacct
gaggaagccctggatactgtcccagcccactactga

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (2)   
   NCBI-Gene (1)   
   NCBI-GI (4)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (2)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (5)   
   PROSITE (1)   
All databases (34)

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