KEGG H.sapiens: 5297

Homo sapiens (human): 5297

Entry

5297 CDS H.sapiens

Gene name PI4KA

Definition phosphatidylinositol 4-kinase, catalytic, alpha (EC:2.7.1.67)

Orthology K00888 phosphatidylinositol 4-kinase [EC:2.7.1.67]

Pathway hsa00562 Inositol phosphate metabolism
hsa01100 Metabolic pathways
hsa04070 Phosphatidylinositol signaling system

Class Metabolism; Carbohydrate Metabolism; Inositol phosphate metabolism
[PATH:hsa00562]
Environmental Information Processing; Signal Transduction;
Phosphatidylinositol signaling system [PATH:hsa04070]

SSDB

Motif Pfam: PI3_PI4_kinase PI3Ka
PROSITE: PI3_4_KINASE_1 PI3_4_KINASE_2 PI3_4_KINASE_3

Other DBs NCBI-GI: 4505807
NCBI-GeneID: 5297
OMIM: 600286
HGNC: 8983
HPRD: 08972
Ensembl: ENSG00000100038
UniProt: P42356

Position 22q11.21

AA seq 854 aa
MREMAGAWHMTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEI
AKYCSSDQVEIFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNA
TIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVP
PDNQDTRSNLDITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKR
RTLLLSLLATEIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAW
SISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSH
VLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGY
VREYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAK
DFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDID
YKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAI
FKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQL
GRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKK
GHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVR
PYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSR
TYDMIQYYQNDIPY

NT seq 2565 nt +upstreamnt +downstreamnt
atgcgggagatggcaggggcctggcacatgacggtggagcagaaatttggcctgttttct
gctgagataaaggaagcagaccccctggctgcctcggaagcaagtcaacccaaaccctgt
ccccccgaagtgaccccccactacatctggatcgacttcctggtgcagcggtttgagatc
gccaagtactgcagctctgaccaagtggagatcttctccagcctgctgcagcgctccatg
tccctgaacatcggcggggccaaggggagcatgaaccggcacgtggcggccatcgggccc
cgcttcaagctgctgaccctggggctgtccctcctgcatgccgatgtggttccaaatgca
accatccgcaatgtgcttcgcgagaagatctactccactgcctttgactacttcagctgt
cccccaaagttccctactcaaggagagaagcggctgcgtgaagacataagcatcatgatt
aaattttggaccgccatgttctcagataagaagtacctgaccgccagccagcttgttccc
ccagataatcaggacacccggagcaacctggacataactgtcggctctcggcaacaagcc
acccaaggctggatcaacacataccccctgtccagcggcatgtccaccatctccaagaaa
tcaggcatgtctaagaaaaccaaccggggctcccagctgcacaaatactacatgaagcgc
aggacgctgctgctgtccctgctggccactgagatcgagcgtctcatcacatggtacaac
ccgctgtcagccccggaactggaactagaccaggccggagagaacagcgtggccaactgg
agatctaagtacatcagcctgagtgagaagcagtggaaggacaacgtgaacctcgcctgg
agcatctctccctacctagccgtgcagctgcctgccaggtttaagaacacagaagccatt
gggaacgaagtgacccgtctcgttcggttggacccgggagccgttagtgatgtgcctgaa
gcaatcaagttcctggtcacctggcacaccatcgacgccgatgctccagagctcagccat
gtgctgtgctgggcgcccacggacccacccacaggcctctcctacttctccagcatgtac
ccgccgcaccctctcacggcgcagtacggggtgaaagtcctgcggtccttccctccggac
gccatcctcttctacatcccccagattgtgcaggccctcaggtacgacaagatgggctat
gtgcgggagtatattctgtgggcagcgtctaaatcccagcttctggcacaccagttcatc
tggaacatgaagactaacatttatctagatgaagagggccaccagaaagaccctgacatc
ggcgacctcctggatcagttggtagaggagatcacaggctccttgtccggcccagcgaag
gacttttaccagcgggagtttgatttctttaacaagatcaccaacgtgtcggctatcatc
aagccctaccctaaaggcgacgagagaaagaaggcttgtctgtcggccctgtctgaagtg
aaggtgcagccgggctgctacctgcccagcaaccctgaggccattgtgctggacatcgac
tacaagtctgggaccccgatgcagagtgctgcaaaagccccatatctggccaagttcaag
gtgaagcgatgtggagttagtgaacttgaaaaagaaggtctgcggtgccgctcagactcc
gaggatgagtgcagcacgcaggaggccgacggccagaagatctcctggcaggcagccatc
ttcaaggtgggagacgactgccggcaggacatgctggccctgcagatcatcgacctcttc
aagaacatcttccagctggtcggcctggacctctttgtttttccctaccgcgtggtggcc
actgcccctgggtgcggggtgatcgagtgcatccccgactgcacctcccgggaccagctg
ggccgccagacagacttcggcatgtacgactacttcacacgccagtacggggatgagtcc
actctggccttccagcaggcccgctacaacttcatccgaagcatggccgcctacagcctc
ctgctgttcctgctgcagatcaaggacagacacaacggcaacattatgctggacaagaag
ggtcatatcatccacatcgactttggcttcatgtttgaaagctcgccgggcggcaatctc
ggctgggaacccgacatcaagctgacggatgagatggtgatgatcatggggggcaagatg
gaggccacacccttcaagtggttcatggagatgtgtgtccgaggctacctggctgtgcgg
ccctacatggacgcggtcgtctccctggtcactctcatgttggacacgggcctgccctgt
tttcgcggccagacaatcaagctcttgaagcacaggtttagccccaacatgactgagcgc
gaggctgcaaatttcatcatgaaggtcatccagagctgcttcctcagcaacaggagccgg
acctacgacatgatccagtactatcagaatgacatcccctactga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (2)   
   IPI (4)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (5)   
   Pfam (2)   
   PROSITE (3)   
All databases (31)

DBGET integrated database retrieval system