KEGG   Homo sapiens (human): 5319Help
Entry
5319              CDS       H.sapiens                              
Gene name PLA2G1B
Definition phospholipase A2, group IB (pancreas) (EC:3.1.1.4)
Orthology K01047  phospholipase A2 [EC:3.1.1.4]
Pathway hsa00564  Glycerophospholipid metabolism
hsa00565  Ether lipid metabolism
hsa00590  Arachidonic acid metabolism
hsa00591  Linoleic acid metabolism
hsa00592  alpha-Linolenic acid metabolism
hsa01100  Metabolic pathways
hsa04010  MAPK signaling pathway
hsa04270  Vascular smooth muscle contraction
hsa04370  VEGF signaling pathway
hsa04664  Fc epsilon RI signaling pathway
hsa04730  Long-term depression
hsa04912  GnRH signaling pathway
Class Metabolism; Lipid Metabolism; Glycerophospholipid metabolism
[PATH:hsa00564]
Metabolism; Lipid Metabolism; Ether lipid metabolism [PATH:hsa00565]
Metabolism; Lipid Metabolism; Arachidonic acid metabolism
[PATH:hsa00590]
Metabolism; Lipid Metabolism; Linoleic acid metabolism
[PATH:hsa00591]
Metabolism; Lipid Metabolism; alpha-Linolenic acid metabolism
[PATH:hsa00592]
Environmental Information Processing; Signal Transduction; MAPK
signaling pathway [PATH:hsa04010]
Environmental Information Processing; Signal Transduction; VEGF
signaling pathway [PATH:hsa04370]
Organismal Systems; Immune System; Fc epsilon RI signaling pathway
[PATH:hsa04664]
Organismal Systems; Endocrine System; GnRH signaling pathway
[PATH:hsa04912]
Organismal Systems; Circulatory System; Vascular smooth muscle
contraction [PATH:hsa04270]
Organismal Systems; Nervous System; Long-term depression
[PATH:hsa04730]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: Phospholip_A2_1 Parvo_coat_N Phospholip_A2_2 DUF1644
PROSITE: PA2_ASP PA2_HIS
Motif
Other DBs NCBI-GI: 4505847
NCBI-GeneID: 5319
OMIM: 172410
HGNC: 9030
HPRD: 01396
Ensembl: ENSG00000170890
UniProt: P04054
Structure
PDB: 3ELO
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Jmol
Position 12q23-q24.1
AA seq 148 aa AA seqDB search
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS
NT seq 447 nt NT seq  +upstreamnt  +downstreamnt
atgaaactccttgtgctagctgtgctgctcacagtggccgccgccgacagcggcatcagc
cctcgggccgtgtggcagttccgcaaaatgatcaagtgcgtgatcccggggagtgacccc
ttcttggaatacaacaactacggctgctactgtggcttggggggctcaggcacccccgtg
gatgaactggacaagtgctgccagacacatgacaactgctatgaccaggccaagaagctg
gacagctgtaaatttctgctggacaacccgtacacccacacctattcatactcgtgctct
ggctcggcaatcacctgtagcagcaaaaacaaagagtgtgaggccttcatttgcaactgc
gaccgcaacgctgccatctgcttttcaaaagctccatataacaaggcacacaagaacctg
gacaccaagaagtattgtcagagttga
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