KEGG H.sapiens: 54187

Homo sapiens (human): 54187

Entry

54187 CDS H.sapiens

Gene name NANS

Definition N-acetylneuraminic acid synthase (EC:2.5.1.56 2.5.1.57)

Orthology K05304 sialic acid synthase [EC:2.5.1.56 2.5.1.57]

Pathway hsa00520 Amino sugar and nucleotide sugar metabolism
hsa01100 Metabolic pathways

Class Metabolism; Carbohydrate Metabolism; Amino sugar and nucleotide
sugar metabolism [PATH:hsa00520]

SSDB

Motif Pfam: NeuB SAF AP_endonuc_2 Ala_racemase_C
PROSITE: AFP_LIKE

Other DBs NCBI-GI: 12056473
NCBI-GeneID: 54187
OMIM: 605202
HGNC: 19237
HPRD: 07285
Ensembl: ENSG00000095380
UniProt: Q9NR45

Structure

PDB: 1WVO

Position 9p24.1-p23

AA seq 359 aa
MPLELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEF
KFNRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVE
FLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFC
FLQCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHIT
LDKTWKGSDHSASLEPGELAELVRSVRLVERALGSPTKQLLPCEMACNEKLGKSVVAKVK
IPEGTILTMDMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS

NT seq 1080 nt +upstreamnt +downstreamnt
atgccgctggagctggagctgtgtcccgggcgctgggtgggcgggcaacacccgtgcttc
atcattgccgagatcggccagaaccaccagggcgacctggacgtagccaagcgcatgatc
cgcatggccaaggagtgtggggctgattgtgctaagttccagaagagtgagctagaattc
aagtttaatcggaaagccttggagaggccatacacctcgaagcattcctgggggaagacg
tacggggagcacaaacgacatctggagttcagccatgaccagtacagggagctgcagagg
tacgccgaggaggttgggatcttcttcactgcctctggcatggatgagatggcagttgaa
ttcctgcatgaactgaatgttccatttttcaaagttggatctggagacactaataatttt
ccttatctggaaaagacagccaaaaaaggtcgcccaatggtgatctccagtgggatgcag
tcaatggacaccatgaagcaagtttatcagatcgtgaagcccctcaaccccaacttctgc
ttcttgcagtgtaccagcgcatacccgctccagcctgaggacgtcaacctgcgggtcatc
tcggaatatcagaagctctttcctgacattcccatagggtattctgggcatgaaacaggc
atagcgatatctgtggccgcagtggctctgggggccaaggtgttggaacgtcacataact
ttggacaagacctggaaggggagtgaccactcggcctcgctggagcctggagaactggcc
gagctggtgcggtcagtgcgtcttgtggagcgtgccctgggctccccaaccaagcagctg
ctgccctgtgagatggcctgcaatgagaagctgggcaagtctgtggtggccaaagtgaaa
attccggaaggcaccattctaacaatggacatgctcaccgtgaaggtgggtgagcccaaa
ggctatcctcctgaagacatctttaatctagtgggcaagaaggtcctggtcactgttgaa
gaggatgacaccatcatggaagaattggtagataatcatggcaaaaaaatcaagtcttaa

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UNIGENE (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (4)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (4)   
   PROSITE (1)   
All databases (38)

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