KEGG   Homo sapiens (human): 54576Help
Entry
54576             CDS       H.sapiens                              
Gene name UGT1A8
Definition UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)
Orthology K00699  glucuronosyltransferase [EC:2.4.1.17]
Pathway hsa00040  Pentose and glucuronate interconversions
hsa00053  Ascorbate and aldarate metabolism
hsa00140  Steroid hormone biosynthesis
hsa00500  Starch and sucrose metabolism
hsa00830  Retinol metabolism
hsa00860  Porphyrin and chlorophyll metabolism
hsa00980  Metabolism of xenobiotics by cytochrome P450
hsa00982  Drug metabolism - cytochrome P450
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
Class Metabolism; Carbohydrate Metabolism; Pentose and glucuronate
interconversions [PATH:hsa00040]
Metabolism; Carbohydrate Metabolism; Ascorbate and aldarate
metabolism [PATH:hsa00053]
Metabolism; Carbohydrate Metabolism; Starch and sucrose metabolism
[PATH:hsa00500]
Metabolism; Lipid Metabolism; Steroid hormone biosynthesis
[PATH:hsa00140]
Metabolism; Glycan Biosynthesis and Metabolism; Glycosyltransferases
Metabolism; Metabolism of Cofactors and Vitamins; Retinol metabolism
[PATH:hsa00830]
Metabolism; Metabolism of Cofactors and Vitamins; Porphyrin and
chlorophyll metabolism [PATH:hsa00860]
Metabolism; Xenobiotics Biodegradation and Metabolism; Metabolism of
xenobiotics by cytochrome P450 [PATH:hsa00980]
Metabolism; Xenobiotics Biodegradation and Metabolism; Drug
metabolism - cytochrome P450 [PATH:hsa00982]
Metabolism; Xenobiotics Biodegradation and Metabolism; Drug
metabolism - other enzymes [PATH:hsa00983]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: UDPGT Glyco_tran_28_C
PROSITE: UDPGT
Motif
Other DBs NCBI-GI: 31377618
NCBI-GeneID: 54576
OMIM: 606433
HGNC: 12540
HPRD: 07072
Ensembl: ENSG00000167165
UniProt: Q5DSZ6 Q9HAW9
Position 2q37
AA seq 530 aa AA seqDB search
MARTGWTSPIPLCVSLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMP
EVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVRSLFSLFLSSSNGFFNLF
FSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEEG
AQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEILQTPVT
AYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIV
VFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGH
PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL
ENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTW
YQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
NT seq 1593 nt NT seq  +upstreamnt  +downstreamnt
atggctcgcacagggtggaccagccccattcccctatgtgtttctctgctgctgacctgt
ggctttgctgaggcagggaagctgctggtagtgcccatggatgggagtcactggttcacc
atgcagtcggtggtggagaaacttatcctcagggggcatgaggtggttgtagtcatgcca
gaggtgagttggcaactgggaaaatcactgaattgcacagtgaagacttactcaacctca
tacactctggaggatctggaccgggaattcatggatttcgccgatgctcaatggaaagca
caagtacgaagtttgttttctctatttctgagttcatccaatggtttttttaacttattt
ttttcgcattgcaggagtttgtttaatgaccgaaaattagtagaatacttaaaggagagt
tcttttgatgcggtgtttcttgatccttttgatgcctgtggcttaattgttgccaaatat
ttctccctcccctctgtggtcttcgccaggggaatagcttgccactatcttgaagaaggt
gcacagtgccctgctcctctttcctatgtccccagaattctcttagggttctcagatgcc
atgactttcaaggagagagtacggaaccacatcatgcacttggaggaacatttattttgc
cagtatttttccaaaaatgccctagaaatagcctctgaaattctccaaacacctgtcaca
gcatatgatctctacagccacacatcaatttggttgttgcgaacagactttgttttggac
tatcccaaacccgtgatgcccaatatgatcttcattggtggtatcaactgccatcaggga
aagccattgcctatggaatttgaagcctacattaatgcttctggagaacatggaattgtg
gttttctctttgggatcaatggtctcagaaattccagagaagaaagctatggcaattgct
gatgctttgggcaaaatccctcagacagtcctgtggcggtacactggaacccgaccatcg
aatcttgcgaacaacacgatacttgttaagtggctaccccaaaacgatctgcttggtcac
ccgatgacccgtgcctttatcacccatgctggttcccatggtgtttatgaaagcatatgc
aatggcgttcccatggtgatgatgcccttgtttggtgatcagatggacaatgcaaagcgc
atggagactaagggagctggagtgaccctgaatgttctggaaatgacttctgaagattta
gaaaatgctctaaaagcagtcatcaatgacaaaagttacaaggagaacatcatgcgcctc
tccagccttcacaaggaccgcccggtggagccgctggacctggccgtgttctgggtggag
tttgtgatgaggcacaagggcgcgccacacctgcgccccgcagcccacgacctcacctgg
taccagtaccattccttggacgtgattggtttcctcttggccgtcgtgctgacagtggcc
ttcatcacctttaaatgttgtgcttatggctaccggaaatgcttggggaaaaaagggcga
gttaagaaagcccacaaatccaagacccattga
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