KEGG   Homo sapiens (human): 54658Help
Entry
54658             CDS       T01001                                 

Gene name
UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A
Definition
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)
Orthology
K00699  
glucuronosyltransferase [EC:2.4.1.17]
Organism
hsa  Homo sapiens (human)
Pathway
Pentose and glucuronate interconversions
Ascorbate and aldarate metabolism
Steroid hormone biosynthesis
Starch and sucrose metabolism
Retinol metabolism
Porphyrin and chlorophyll metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes
Metabolic pathways
Chemical carcinogenesis
Disease
H00208  
Hyperbilirubinemia
Class
Metabolism; Carbohydrate metabolism; Pentose and glucuronate interconversions [PATH:hsa00040]
Metabolism; Carbohydrate metabolism; Ascorbate and aldarate metabolism [PATH:hsa00053]
Metabolism; Carbohydrate metabolism; Starch and sucrose metabolism [PATH:hsa00500]
Metabolism; Lipid metabolism; Steroid hormone biosynthesis [PATH:hsa00140]
Metabolism; Metabolism of cofactors and vitamins; Retinol metabolism [PATH:hsa00830]
Metabolism; Metabolism of cofactors and vitamins; Porphyrin and chlorophyll metabolism [PATH:hsa00860]
Metabolism; Xenobiotics biodegradation and metabolism; Metabolism of xenobiotics by cytochrome P450 [PATH:hsa00980]
Metabolism; Xenobiotics biodegradation and metabolism; Drug metabolism - cytochrome P450 [PATH:hsa00982]
Metabolism; Xenobiotics biodegradation and metabolism; Drug metabolism - other enzymes [PATH:hsa00983]
Human Diseases; Cancers; Chemical carcinogenesis [PATH:hsa05204]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
2q37
AA seq 533 aa AA seqDB search
MAVESQGGRPLVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSMLGAIQQLQQRGHEIVVL
APDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFENDSFLQRVIKTYKKIKKDS
AMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLE
FEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQR
EVTVQDLLSSASVWLFRSDFVKDYPRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGEH
GIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDL
LGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTS
EDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHD
LTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
NT seq 1602 nt NT seq  +upstreamnt  +downstreamnt
atggctgtggagtcccagggcggacgcccacttgtcctgggcctgctgctgtgtgtgctg
ggcccagtggtgtcccatgctgggaagatactgttgatcccagtggatggcagccactgg
ctgagcatgcttggggccatccagcagctgcagcagaggggacatgaaatagttgtccta
gcacctgacgcctcgttgtacatcagagacggagcattttacaccttgaagacgtaccct
gtgccattccaaagggaggatgtgaaagagtcttttgttagtctcgggcataatgttttt
gagaatgattctttcctgcagcgtgtgatcaaaacatacaagaaaataaaaaaggactct
gctatgcttttgtctggctgttcccacttactgcacaacaaggagctcatggcctccctg
gcagaaagcagctttgatgtcatgctgacggaccctttccttccttgcagccccatcgtg
gcccagtacctgtctctgcccactgtattcttcttgcatgcactgccatgcagcctggaa
tttgaggctacccagtgccccaacccattctcctacgtgcccaggcctctctcctctcat
tcagatcacatgaccttcctgcagcgggtgaagaacatgctcattgccttttcacagaac
tttctgtgcgacgtggtttattccccgtatgcaacccttgcctcagaattccttcagaga
gaggtgactgtccaggacctattgagctctgcatctgtctggctgtttagaagtgacttt
gtgaaggattaccctaggcccatcatgcccaatatggtttttgttggtggaatcaactgc
cttcaccaaaatccactatcccaggaatttgaagcctacattaatgcttctggagaacat
ggaattgtggttttctctttgggatcaatggtctcagaaattccagagaagaaagctatg
gcaattgctgatgctttgggcaaaatccctcagacagtcctgtggcggtacactggaacc
cgaccatcgaatcttgcgaacaacacgatacttgttaagtggctaccccaaaacgatctg
cttggtcacccgatgacccgtgcctttatcacccatgctggttcccatggtgtttatgaa
agcatatgcaatggcgttcccatggtgatgatgcccttgtttggtgatcagatggacaat
gcaaagcgcatggagactaagggagctggagtgaccctgaatgttctggaaatgacttct
gaagatttagaaaatgctctaaaagcagtcatcaatgacaaaagttacaaggagaacatc
atgcgcctctccagccttcacaaggaccgcccggtggagccgctggacctggccgtgttc
tgggtggagtttgtgatgaggcacaagggcgcgccacacctgcgccccgcagcccacgac
ctcacctggtaccagtaccattccttggacgtgattggtttcctcttggccgtcgtgctg
acagtggccttcatcacctttaaatgttgtgcttatggctaccggaaatgcttggggaaa
aaagggcgagttaagaaagcccacaaatccaagacccattga

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