KEGG   Homo sapiens (human): 54658Help
Entry
54658             CDS       H.sapiens                              
Gene name UGT1A1
Definition UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)
Orthology K00699  glucuronosyltransferase [EC:2.4.1.17]
Pathway hsa00040  Pentose and glucuronate interconversions
hsa00053  Ascorbate and aldarate metabolism
hsa00140  Steroid hormone biosynthesis
hsa00500  Starch and sucrose metabolism
hsa00830  Retinol metabolism
hsa00860  Porphyrin and chlorophyll metabolism
hsa00980  Metabolism of xenobiotics by cytochrome P450
hsa00982  Drug metabolism - cytochrome P450
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
Disease H00208  Hyperbilirubinemia
Class Metabolism; Carbohydrate Metabolism; Pentose and glucuronate
interconversions [PATH:hsa00040]
Metabolism; Carbohydrate Metabolism; Ascorbate and aldarate
metabolism [PATH:hsa00053]
Metabolism; Carbohydrate Metabolism; Starch and sucrose metabolism
[PATH:hsa00500]
Metabolism; Lipid Metabolism; Steroid hormone biosynthesis
[PATH:hsa00140]
Metabolism; Glycan Biosynthesis and Metabolism; Glycosyltransferases
Metabolism; Metabolism of Cofactors and Vitamins; Retinol metabolism
[PATH:hsa00830]
Metabolism; Metabolism of Cofactors and Vitamins; Porphyrin and
chlorophyll metabolism [PATH:hsa00860]
Metabolism; Xenobiotics Biodegradation and Metabolism; Metabolism of
xenobiotics by cytochrome P450 [PATH:hsa00980]
Metabolism; Xenobiotics Biodegradation and Metabolism; Drug
metabolism - cytochrome P450 [PATH:hsa00982]
Metabolism; Xenobiotics Biodegradation and Metabolism; Drug
metabolism - other enzymes [PATH:hsa00983]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: UDPGT Glyco_tran_28_C
PROSITE: UDPGT
Motif
Other DBs NCBI-GI: 8850236
NCBI-GeneID: 54658
OMIM: 191740
HGNC: 12530
HPRD: 08933
Ensembl: ENSG00000167165
UniProt: P22309 Q5DT03
Position 2q37
AA seq 533 aa AA seqDB search
MAVESQGGRPLVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSMLGAIQQLQQRGHEIVVL
APDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFENDSFLQRVIKTYKKIKKDS
AMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLE
FEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQR
EVTVQDLLSSASVWLFRSDFVKDYPRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGEH
GIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDL
LGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTS
EDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHD
LTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
NT seq 1602 nt NT seq  +upstreamnt  +downstreamnt
atggctgtggagtcccagggcggacgcccacttgtcctgggcctgctgctgtgtgtgctg
ggcccagtggtgtcccatgctgggaagatactgttgatcccagtggatggcagccactgg
ctgagcatgcttggggccatccagcagctgcagcagaggggacatgaaatagttgtccta
gcacctgacgcctcgttgtacatcagagacggagcattttacaccttgaagacgtaccct
gtgccattccaaagggaggatgtgaaagagtcttttgttagtctcgggcataatgttttt
gagaatgattctttcctgcagcgtgtgatcaaaacatacaagaaaataaaaaaggactct
gctatgcttttgtctggctgttcccacttactgcacaacaaggagctcatggcctccctg
gcagaaagcagctttgatgtcatgctgacggaccctttccttccttgcagccccatcgtg
gcccagtacctgtctctgcccactgtattcttcttgcatgcactgccatgcagcctggaa
tttgaggctacccagtgccccaacccattctcctacgtgcccaggcctctctcctctcat
tcagatcacatgaccttcctgcagcgggtgaagaacatgctcattgccttttcacagaac
tttctgtgcgacgtggtttattccccgtatgcaacccttgcctcagaattccttcagaga
gaggtgactgtccaggacctattgagctctgcatctgtctggctgtttagaagtgacttt
gtgaaggattaccctaggcccatcatgcccaatatggtttttgttggtggaatcaactgc
cttcaccaaaatccactatcccaggaatttgaagcctacattaatgcttctggagaacat
ggaattgtggttttctctttgggatcaatggtctcagaaattccagagaagaaagctatg
gcaattgctgatgctttgggcaaaatccctcagacagtcctgtggcggtacactggaacc
cgaccatcgaatcttgcgaacaacacgatacttgttaagtggctaccccaaaacgatctg
cttggtcacccgatgacccgtgcctttatcacccatgctggttcccatggtgtttatgaa
agcatatgcaatggcgttcccatggtgatgatgcccttgtttggtgatcagatggacaat
gcaaagcgcatggagactaagggagctggagtgaccctgaatgttctggaaatgacttct
gaagatttagaaaatgctctaaaagcagtcatcaatgacaaaagttacaaggagaacatc
atgcgcctctccagccttcacaaggaccgcccggtggagccgctggacctggccgtgttc
tgggtggagtttgtgatgaggcacaagggcgcgccacacctgcgccccgcagcccacgac
ctcacctggtaccagtaccattccttggacgtgattggtttcctcttggccgtcgtgctg
acagtggccttcatcacctttaaatgttgtgcttatggctaccggaaatgcttggggaaa
aaagggcgagttaagaaagcccacaaatccaagacccattga
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