KEGG H.sapiens: 6652

Homo sapiens (human): 6652

Entry

6652 CDS H.sapiens

Gene name SORD

Definition sorbitol dehydrogenase (EC:1.1.1.14)

Orthology K00008 L-iditol 2-dehydrogenase [EC:1.1.1.14]

Pathway hsa00051 Fructose and mannose metabolism
hsa01100 Metabolic pathways

Class Metabolism; Carbohydrate Metabolism; Fructose and mannose metabolism
[PATH:hsa00051]

SSDB

Motif Pfam: ADH_zinc_N ADH_N 2-Hacid_dh_C
PROSITE: ADH_ZINC

Other DBs NCBI-GI: 156627571
NCBI-GeneID: 6652
OMIM: 182500
HGNC: 11184
HPRD: 01679
Ensembl: ENSG00000140263
UniProt: Q00796

Structure

PDB: 1PL8 1PL6 1PL7

Position 15q15.3

AA seq 357 aa
MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF
IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFC
ATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCG
AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL
GCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRY
CNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP

NT seq 1074 nt +upstreamnt +downstreamnt
atggcggcggcggccaagcccaacaacctttccctggtggtgcacggaccgggggacttg
cgcctggagaactatcctatccctgaaccaggcccaaatgaggtcttgctgaggatgcat
tctgttggaatctgtggctcagatgtccactactgggagtatggtcgaattgggaatttt
attgtgaaaaagcccatggtgctgggacatgaagcttcgggaacagtcgaaaaagtggga
tcatcggtaaagcacctaaaaccaggtgatcgtgttgccatcgagcctggtgctccccga
gaaaatgatgaattctgcaagatgggccgatacaatctgtcaccttccatcttcttctgt
gccacgccccccgatgacgggaacctctgccggttctataagcacaatgcagccttttgt
tacaagcttcctgacaatgtcacctttgaggaaggcgccctgatcgagccactttctgtg
gggatccatgcctgcaggagaggcggagttaccctgggacacaaggtccttgtgtgtgga
gctgggccaatcgggatggtcactttgctcgtggccaaagcaatgggagcagctcaagta
gtggtgactgatctgtctgctacccgattgtccaaagccaaggagattggggctgattta
gtcctccagatctccaaggagagccctcaggaaatcgccaggaaagtagaaggtcagctg
gggtgcaagccggaagtcaccatcgagtgcacgggggcagaggcctccatccaggcgggc
atctacgccactcgctctggtgggaacctcgtgcttgtggggctgggctctgagatgacc
accgtacccctactgcatgcagccatccgggaggtggatatcaagggcgtgtttcgatac
tgcaacacgtggccagtggcgatttcgatgcttgcgtccaagtctgtgaatgtaaaaccc
ctcgtcacccataggtttcctctggagaaagctctggaggcctttgaaacatttaaaaag
ggattggggttgaaaatcatgctcaagtgtgaccccagtgaccagaatccctga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UNIGENE (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (2)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
3D Structure (3)   
   PDB (3)   
Protein domain (4)   
   Pfam (3)   
   PROSITE (1)   
All databases (39)

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