KEGG H.sapiens: 6916

Homo sapiens (human): 6916

Entry

6916 CDS H.sapiens

Gene name TBXAS1

Definition thromboxane A synthase 1 (platelet) (EC:5.3.99.5)

Orthology K01832 cytochrome P450, family 5, subfamily A (thromboxane-A
synthase) [EC:5.3.99.5]

Pathway hsa00590 Arachidonic acid metabolism
hsa01100 Metabolic pathways

Class Metabolism; Lipid Metabolism; Arachidonic acid metabolism
[PATH:hsa00590]
Metabolism; Enzyme Families; Cytochrome P450

SSDB

Motif Pfam: p450
PROSITE: CYTOCHROME_P450

Other DBs NCBI-GI: 195972898
NCBI-GeneID: 6916
OMIM: 274180
HGNC: 11609
HPRD: 02035
Ensembl: ENSG00000059377
UniProt: P24557 Q53F23

Position 7q34-q35

AA seq 534 aa
MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
NPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCE
VLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSC
LGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR

NT seq 1605 nt +upstreamnt +downstreamnt
atgatggaagccttggggtttctaaaattggaagtgaatggccccatggtgacggtggcc
ctgtcagtggctctcttggccctcctgaaatggtactccacatcagcattctcaagactg
gagaagttaggcctcagacatcccaagccttctcctttcattggaaacttgacatttttc
cgccagggtttttgggaaagccaaatggagctcagaaagctgtatggacctctgtgtggg
tactatcttggtcgtcggatgtttattgttatttctgagccagacatgatcaagcaggtg
ttggttgagaacttcagtaactttaccaacagaatggcgtcgggtttggagttcaagtcg
gtagccgacagcgttctgtttttacgtgacaaaagatgggaagaggtcagaggtgccctg
atgtctgctttcagtcctgaaaagctgaacgagatggttcccctcatcagccaagcctgc
gaccttctcctggctcatttaaaacgctatgcggaatctggggacgcatttgacatccag
aggtgctactgcaattacaccacagatgtggttgccagcgtcgcctttggcaccccggtg
gactcctggcaggcccctgaggatccctttgtgaaacactgcaagcgtttcttcgaattc
tgcatccccagacctatcctggttttactcttatcatttccatccataatggtcccactg
gcccggattttgcccaataagaaccgagacgaactgaatggcttttttaacaaactcatt
aggaatgtgattgccttgcgggaccagcaagctgccgaagagaggcggagagacttcctc
caaatggtcctggatgcccgacattctgcaagtcccatgggcgtgcaagactttgacatc
gtcagagacgttttctcctctactgggtgcaagccgaacccttcccggcaacaccagccc
agccctatggccaggcctttgactgtggatgagattgtgggccaggccttcatcttcctc
atcgctggctatgaaatcatcaccaacacactttcttttgccacctacctactggccacc
aaccctgactgccaagagaagcttctgagagaggtagacgtttttaaggagaaacacatg
gcccctgagttctgcagcctcgaggaaggcctgccctatctggacatggtgattgcagag
acgctgaggatgtacccgccagctttcagattcacacgggaggcagctcaggactgcgag
gtgctggggcagcgcatccccgcaggcgctgtgctagagatggccgtgggtgccctgcac
catgaccctgagcactggccaagcccggagaccttcaaccctgaaaggttcacggctgag
gcccggcagcagcaccggcccttcacgtacctgcccttcggggccggcccacggagctgc
ctcggggtgcgtctagggctgcttgaggtcaagttgacactgctccacgtgctgcacaag
ttccggttccaagcctgccctgagacccaggtaccgctgcagctagaatccaaatctgcc
ctaggtccaaaaaatggtgtctatatcaagatcgtatcccgctga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (9)   
   KEGG DRUG (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (18)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (16)   
   UniProt (2)   
   RefSeq(pep) (5)   
   IPI (9)   
DNA sequence (41)   
   RefSeq(nuc) (5)   
   GenBank (18)   
   EMBL (18)   
Protein domain (2)   
   Pfam (1)   
   PROSITE (1)   
All databases (97)

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