KEGG H.sapiens: 7378

Homo sapiens (human): 7378

Entry

7378 CDS H.sapiens

Gene name UPP1

Definition uridine phosphorylase 1 (EC:2.4.2.3)

Orthology K00757 uridine phosphorylase [EC:2.4.2.3]

Pathway hsa00240 Pyrimidine metabolism
hsa00983 Drug metabolism - other enzymes
hsa01100 Metabolic pathways

Class Metabolism; Nucleotide Metabolism; Pyrimidine metabolism
[PATH:hsa00240]
Metabolism; Xenobiotics Biodegradation and Metabolism; Drug
metabolism - other enzymes [PATH:hsa00983]

SSDB

Motif Pfam: PNP_UDP_1
PROSITE: PNP_UDP_1

Other DBs NCBI-GI: 4507839
NCBI-GeneID: 7378
OMIM: 191730
HGNC: 12576
HPRD: 08932
Ensembl: ENSG00000183696
UniProt: Q16831

Structure

PDB: 3EUF 3EUE

Position 7p12.3

AA seq 310 aa
MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG
SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH
ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT
DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY
AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS
YFIKKKLSKA

NT seq 933 nt +upstreamnt +downstreamnt
atggcggccacgggagccaatgcagagaaagctgaaagtcacaatgattgccccgtcaga
cttttaaatccaaacatagcaaaaatgaaagaagatattctctatcatttcaatctcacc
actagcagacacaatttcccagccttgtttggagatgtgaagtttgtgtgtgttggtgga
agcccctcccggatgaaagccttcatcaggtgcgttggtgcagagctgggccttgactgc
ccaggtagagactatcccaacatctgtgcgggaactgaccgctatgccatgtataaagta
ggaccggtgctgtctgtcagtcatggtatgggcattccttctatctcaatcatgttgcat
gagctcataaagctgctgtactatgcccggtgctccaacgtcactatcatccgcattggc
acttctggtgggataggtctggagcccggcactgtggtcataacagagcaggcagtggat
acctgcttcaaggcagagtttgagcagattgtcctggggaagcgggtcatccggaaaacg
gaccttaacaagaagctggtgcaggagctgttgctgtgttctgcagagctgagcgagttc
accacagtggtggggaacaccatgtgcaccttggacttctatgaagggcaaggccgtctg
gatggggctctctgctcctacacggagaaggacaagcaggcgtatctggaggcagcctat
gcagccggcgtccgcaatatcgagatggagtcctcggtgtttgccgccatgtgcagcgcc
tgcggcctccaagcggccgtggtgtgtgtcaccctcctgaaccgcctggaaggggaccag
atcagcagccctcgcaatgtgctcagcgagtaccagcagaggccgcagcggctggtgagc
tacttcatcaagaagaaactgagcaaggcctga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (10)   
   UniProt (1)   
   RefSeq(pep) (2)   
   IPI (7)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
3D Structure (2)   
   PDB (2)   
Protein domain (2)   
   Pfam (1)   
   PROSITE (1)   
All databases (41)

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