KEGG H.sapiens: 7407

Homo sapiens (human): 7407

Entry

7407 CDS H.sapiens

Gene name VARS

Definition valyl-tRNA synthetase (EC:6.1.1.9)

Orthology K01873 valyl-tRNA synthetase [EC:6.1.1.9]

Pathway hsa00290 Valine, leucine and isoleucine biosynthesis
hsa00970 Aminoacyl-tRNA biosynthesis

Class Metabolism; Amino Acid Metabolism; Valine, leucine and isoleucine
biosynthesis [PATH:hsa00290]
Genetic Information Processing; Translation; Aminoacyl-tRNA
biosynthesis [PATH:hsa00970]

SSDB

Motif Pfam: tRNA-synt_1 Anticodon_1 GST_N tRNA-synt_1g GST_C
Val_tRNA-synt_C tRNA-synt_1e tRNA-synt_1d
PROSITE: AA_TRNA_LIGASE_I

Other DBs NCBI-GI: 5454158
NCBI-GeneID: 7407
OMIM: 192150
HGNC: 12651
HPRD: 10362
Ensembl: ENSG00000204394
UniProt: P26640

Position 6p21.3

AA seq 1264 aa
MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRTPFPPPRLPAL
EQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALG
LRSSAQDPQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLPFRYVLDPPA
RRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPEAPALPKTAAQLKKEAKK
REKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPPGEKKDVSGPMPDSY
SPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAI
QDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQEVWKWK
EEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCT
LNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRIET
MLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPAHDQND
YEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVV
PLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAWMDNIREWC
ISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEFGVSPDKISL
QQDEDVLDTWFSSGLFPLSILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKL
TGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVE
KAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFA
LRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLY
ELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRMP
QAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRADYNLTRIRPDCFLEVAD
EATGALASAVSGYVQALASAGVVAVLALGAPAPQGCAVALASDRCSIHLQLQGLVDPARE
LGKLQAKRVEAQRQAQRLRERRAASGYPVKVPLEVQEADEAKLQQTEAELRKVDEAIALF
QKML

NT seq 3795 nt +upstreamnt +downstreamnt
atgtccaccctctacgtctcccctcacccagatgccttccccagcctccgagccctcata
gccgctcgctatggggaggctggggagggtcccggatggggaggagcccacccccgcatc
tgtctccagccacccccgactagcaggactccctttcccccaccccgcctgccggccctg
gagcaggggcccggtgggctctgggtgtggggggccacggctgtggcccagctgctgtgg
ccagcaggcctggggggcccagggggcagccgggcggctgtccttgtccaacagtgggtc
agttacgccgacacggagttaataccagctgcctgtggagcaacgctgccggccctggga
ctccgaagctcggcccaggacccccaggctgtgctgggggccctgggcagggccctgagc
cccttggaggagtggcttcggctgcacacctacttggccggggaggcccccactctggct
gacctggcggctgtcacagccttgctgctgcctttccgatacgtcctagacccacctgcc
cgccggatctggaataatgtgactcgctggtttgtcacgtgtgtccggcagccagaattc
cgagccgtgctaggagaagtggttctatactcaggagccaggcctctctctcatcagcca
ggccccgaggctcctgccctcccaaagacagctgctcagctcaagaaagaggcaaagaaa
cgggagaagctagagaaattccaacagaagcagaagatccaacagcagcagccacctcca
ggggagaagaaaccaaaaccagagaagagggagaaacgggatcctggggtcattacctat
gacctcccaaccccacccggggaaaagaaagatgtcagtggccccatgcccgactcctac
agccctcggtatgtggaggctgcctggtacccttggtgggagcagcagggcttcttcaag
ccagagtatgggcgtcctaatgtgtcagcagcaaatccccgaggtgtcttcatgatgtgc
atcccaccccccaatgtgacaggctccctgcacctgggccatgcactcaccaacgccatc
caggactccctgactcgatggcaccgcatgcgtggggagaccaccctgtggaaccctggc
tgtgaccatgcaggtattgccacccaggtggtggtggagaagaagctatggcgtgagcag
ggactgagccggcaccagctgggccgcgaggcctttctacaggaagtctggaagtggaag
gaggagaaaggtgaccggatttaccaccagttgaagaagcttggcagctccttggactgg
gatcgagcctgtttcaccatggaccctaaactctcagcagctgtgacagaggcctttgtc
cggcttcacgaggaaggcatcatctatcgcagtacccgccttgttaactggtcctgcacc
ctcaactccgccatctctgacattgaggtggataagaaggagctgacaggtcgcaccctg
ctctccgtgcctggctacaaggagaaggtggagttcggggtcctcgtgtcctttgcctat
aaggtccaaggctcagatagcgacgaggaggtggtggtggcaacaactcggatcgagaca
atgctgggagatgtggctgtagctgtgcaccccaaagataccagataccagcacctgaag
gggaagaacgtgatccacccattcctgtctcggagccttcccattgtcttcgatgaattt
gtggacatggactttggcacaggtgctgtgaagatcacccccgcacatgaccaaaatgac
tatgaagttgggcagcggcacgggctggaggccatcagcatcatggactcccggggggcc
ctcatcaatgtgcctccgcctttcctgggcctgcccaggtttgaggccaggaaagcggtg
ctggtggcgctgaaggagcggggactgttccgtggcattgaggacaaccccatggtggtg
ccactttgcaaccggtcgaaggacgtggtagagcctctgctgcggccgcagtggtacgtt
cgctgcggggagatggcccaggctgccagcgccgctgtgactcggggtgacctccgcatc
ctgcctgaggcccatcagcgcacatggcatgcctggatggacaacatccgggagtggtgc
atttccaggcagctgtggtggggccatcgcatcccagcctactttgtcactgtcagtgac
ccagcggtgccccctggggaggaccctgatgggcggtactgggtgagtggacgcaatgag
gcggaggcccgggagaaggcagccaaggagttcggagtgtcccctgacaagatcagtctc
cagcaagatgaggatgtattggatacctggttctcctctggcctcttccccttatccatt
ttgggctggcccaaccagtcagaagacctgagtgtgttctaccccgggacactgctggag
accggtcatgacatcctcttcttctgggtggcccggatggtcatgctgggcctgaagctc
acgggcaggctgccctttagagaggtctacctccatgccatcgtgcgagatgctcacggc
cggaagatgagcaagtctctaggcaatgtcatcgatcccctggacgtcatctatggaatc
tccctgcagggcctccacaaccagctgctgaacagcaacctggatcccagcgaggtggag
aaggccaaagaagggcagaaagctgacttcccagcggggattcctgaatgtggcaccgat
gctctccggtttggattatgtgcctacatgtcccagggtcgtgacatcaacctggatgtg
aaccggatactgggttaccgccacttctgcaacaagctctggaatgccaccaagtttgcc
cttcgtggccttgggaagggttttgtgccctcacccacctcccagcccggaggccatgag
agcctggtggaccgctggatccgcagccgcctgacagaggctgtgaggctcagcaatcaa
ggcttccaggcctacgacttcccggccgtcaccactgcccagtacagcttctggctctat
gagctctgtgatgtctacttggagtgcctgaaacctgtactgaatggggtggaccaggtg
gcagctgagtgtgcccgccagaccctgtacacttgcctggacgttggcctgcggctgctc
tcacccttcatgcccttcgtgacggaggagctgttccagaggctgccccggaggatgccg
caagctccccctagcctctgtgttaccccctacccggagccctcagagtgctcctggaag
gaccccgaggcagaagccgcccttgagctggcgctaagcatcacgcgagccgtgcgctcc
ctgcgggccgactacaacctcacccggatccggcctgactgtttcctggaagtggcggat
gaggccacgggcgccctggcatcggcggtgtcgggctacgtgcaggccctggccagcgca
ggtgtggtggctgttctggccctgggggctcccgccccccagggttgcgctgtggctctg
gcttctgatcgctgctccatccacctgcagcttcaggggctggtggaccctgcacgggag
ctgggcaagctgcaagccaagcgagttgaggcccagcggcaggcccagcgtctgcgggaa
cgccgtgctgcctcgggctatcctgtcaaggtgccgctcgaagtccaggaggcagatgaa
gccaagctccaacagacagaagcagagctcaggaaggtggatgaggccatcgccctattc
cagaagatgctgtga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (20)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (11)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (9)   
DNA sequence (23)   
   RefSeq(nuc) (1)   
   GenBank (11)   
   EMBL (11)   
Protein domain (9)   
   Pfam (8)   
   PROSITE (1)   
All databases (74)

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