KEGG H.sapiens: 8050

Homo sapiens (human): 8050

Entry

8050 CDS H.sapiens

Gene name PDHX

Definition pyruvate dehydrogenase complex, component X

Disease H00072 Pyruvate dehydrogenase complex deficiency

Class

SSDB

Motif Pfam: 2-oxoacid_dh Biotin_lipoyl E3_binding HlyD GCV_H QRPTase_N
PROSITE: LIPOYL BIOTINYL_LIPOYL

Other DBs NCBI-GI: 203098816
NCBI-GeneID: 8050
OMIM: 608769
HGNC: 21350
HPRD: 02002
Ensembl: ENSG00000110435
UniProt: O00330

Structure

PDB: 2F60 2F5Z 1ZY8 2DNC

Position 11p13

AA seq 486 aa
MQSGGAEGSPGAGRTGRGPGSGKAPPAEISSGAPDFPGGDPIKILMPSLSPTMEEGNIVK
WLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEG
EDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKH
SLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSY
PRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKV
RQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLT
PIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPP
QACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLE
NPIRLA

NT seq 1461 nt +upstreamnt +downstreamnt
atgcaatcaggcggcgctgagggcagcccgggggcggggcgaacggggcgggggccgggg
tctggtaaggccccgccggctgagatatccagcggcgcacctgacttcccgggaggtgat
cccattaagatactaatgccatcactgtctcctacaatggaagaaggaaacattgtgaaa
tggctgaaaaaggaaggtgaagcggtgagtgctggagatgcattatgtgaaattgagact
gacaaagctgtggttaccttagatgcaagtgatgatggaatcttggccaaaatcgtggtt
gaagaaggaagtaaaaatatacggctaggttcactaattggtttgatagtagaagaagga
gaagattggaaacatgttgaaattcccaaagacgtaggtcctccaccaccagtttcaaaa
ccttcagagcctcgcccctcaccagaaccacagatttccatccctgtcaagaaggaacac
atacccgggacactacggttccgtttaagtccagctgcccgcaatattctggaaaaacac
tcactggatgctagccagggcacagccactggccctcgggggatattcactaaagaggat
gctctcaaacttgtccagttgaaacaaacgggcaagattaccgagtccagaccaactcca
gcccccacagccactcccacagcaccttcgcccctacaggccacagctggaccatcttat
ccccggcctgtgatcccaccagtatcaactcctggacaacccaatgcagtgggcacattc
actgaaatccccgccagcaatattcgaagagttattgccaagagattaactgaatctaaa
agtactgtacctcatgcatatgctactgctgactgtgaccttggagctgttttaaaagtt
aggcaagatctggtcaaagatgacattaaagtatcagtaaatgattttatcatcaaggca
gcagctgttacccttaaacaaatgccagatgttaatgtaagctgggatggagagggccca
aagcaactgccatttattgacatttcagtggctgtggcaacagataaaggcttacttact
ccaatcataaaagatgctgctgctaaaggtatccaggaaattgctgactctgtaaaggct
ctatcaaagaaagcaagagatggaaaattgttgcctgaagaataccaaggaggatctttt
agtatttccaacttggggatgtttggcatcgacgaatttactgcagtgattaaccctcct
caggcctgcattttggcggttgggaggttccgacctgtgctgaagctcactgaggatgaa
gagggaaatgccaaactgcagcagcgccagctcataacagtcacaatgtcaagtgacagt
cgagtggttgatgacgaactggcaaccaggtttcttaaaagttttaaagcaaacctagag
aatcctatccgacttgcctag

All links

Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (3)   
   IPI (3)   
DNA sequence (11)   
   RefSeq(nuc) (3)   
   GenBank (4)   
   EMBL (4)   
3D Structure (4)   
   PDB (4)   
Protein domain (8)   
   Pfam (6)   
   PROSITE (2)   
All databases (43)

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