KEGG H.sapiens: 8871

Homo sapiens (human): 8871

Entry

8871 CDS H.sapiens

Gene name SYNJ2

Definition synaptojanin 2 (EC:3.1.3.36)

Orthology K01099 phosphatidylinositol-bisphosphatase [EC:3.1.3.36]

Pathway hsa00562 Inositol phosphate metabolism
hsa01100 Metabolic pathways
hsa04070 Phosphatidylinositol signaling system

Class Metabolism; Carbohydrate Metabolism; Inositol phosphate metabolism
[PATH:hsa00562]
Environmental Information Processing; Signal Transduction;
Phosphatidylinositol signaling system [PATH:hsa04070]

SSDB

Motif Pfam: Syja_N DUF1866 Exo_endo_phos
PROSITE: PRO_RICH RRM SAC

Other DBs NCBI-GI: 26190608
NCBI-GeneID: 8871
OMIM: 609410
HGNC: 11504
HPRD: 10259
Ensembl: ENSG00000078269
UniProt: O15056

Structure

PDB: 1UFW

Position 6q25.3

AA seq 1496 aa
MALSKGLRLLGRLGAEGDCSVLLEARGRDDCLLFEAGTVATLAPEEKEVIKGQYGKLTDA
YGCLGELRLKSGGTSLSFLVLVTGCTSVGRIPDAEIYKITATDFYPLQEEAKEEERLIAL
KKILSSGVFYFSWPNDGSRFDLTVRTQKQGDDSSEWGNSFFWNQLLHVPLRQHQVSCCDW
LLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQMIY
MDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQVV
VNLLGSRGGEEVLNRAFKKLLWASCHAGDTPMINFDFHQFAKGGKLEKLETLLRPQLKLH
WEDFDVFTKGENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALEVLHLQLKTLGLSSKPIV
DRFVESFKAMWSLNGHSLSKVFTGSRALEGKAKVGKLKDGARSMSRTIQSNFFDGVKQEA
IKLLLVGDVYGEEVADKGGMLLDSTALLVTPRILKAMTERQSEFTNFKRIRIAMGTWNVN
GGKQFRSNVLRTAELTDWLLDSPQLSGATDSQDDSSPADIFAVGFEEMVELSAGNIVNAS
TTNKKMWGEQLQKAISRSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGG
KAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYKEITQKLCFPMGRNVFSHDY
VFWCGDFNYRIDLTYEEVFYFVKRQDWKKLLEFDQLQLQKSSGKIFKDFHEGAINFGPTY
KYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVDTKVRHTWSPG
ALQYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSFQGPLDATVVVNLQSPT
LEEKNEFPEDLRTELMQTLGSYGTIVLVRINQGQMLVTFADSHSALSVLDVDGMKVKGRA
VKIRPKTKDWLKGLREEIIRKRDSMAPVSPTANSCLLEENFDFTSLDYESEGDILEDDED
YLVDEFNQPGVSDSELGGDDLSDVPGPTALAPPSKSPALTKKKQHPTYKDDADLVELKRE
LEAVGEFRHRSPSRSLSVPNRPRPPQPPQRPPPPTGLMVKKSASDASISSGTHGQYSILQ
TARLLPGAPQQPPKARTGISKPYNVKQIKTTNAQEAEAAIRCLLEARGGASEEALSAVAP
RDLEASSEPEPTPGAAKPETPQAPPLLPRRPPPRVPAIKKPTLRRTGKPLSPEEQFEQQT
VHFTIGPPETSVEAPPVVTAPRVPPVPKPRTFQPGKAAERPSHRKPASDEAPPGAGASVP
PPLEAPPLVPKVPPRRKKSAPAAFHLQVLQSNSQLLQGLTYNSSDSPSGHPPAAGTVFPQ
GDFLSTSSATSPDSDGTKAMKPEAAPLLGDYQDPFWNLLHHPKLLNNTWLSKSSDPLDSG
TRSPKRDPIDPVSAGASAAKAELPPDHEHKTLGHWVTISDQEKRTALQVFDPLAKT

NT seq 4491 nt +upstreamnt +downstreamnt
atggccctgagcaaagggctgcggctgctggggcgcctgggggccgagggggactgtagc
gtgctgctggaggcgcgcggccgcgacgactgcctgctgttcgaggccggcacggtggcc
acgctggctccagaagaaaaggaagtcattaaaggacagtatggcaagctcacggacgcg
tacggctgcctgggggagctgaggctgaaatctggtggcacgtctctgagcttcctggtg
ttggtgacaggctgcacatctgtgggcagaattccagatgctgaaatctacaaaatcact
gccactgacttttaccctcttcaggaagaggccaaggaggaggaacgcctcatagctttg
aagaaaatcctcagctcgggggtgttctatttctcatggccaaacgatgggtctcgcttt
gacctgactgtccgcacgcagaagcagggggatgacagctctgaatgggggaactccttc
ttctggaaccagctgttgcacgtgcccttgaggcagcaccaggtgagctgctgtgactgg
ctgctgaagatcatctgcggggtggtcaccatccgcaccgtgtatgcctcccacaagcag
gccaaggcctgcctcgtctctcgcgttagctgtgagcgcacaggcactcgcttccacacc
cgtggcgtgaacgacgacggccatgtgtccaacttcgtggagacagagcagatgatttac
atggacgatggagtgtcatcttttgtccagatcagaggctccgttccgctgttctgggaa
cagccagggcttcaggttggctcccatcatctgagactccacagaggcctggaagccaat
gcccctgctttcgacaggcacatggtgcttctgaaggagcagtacgggcagcaggtggtc
gtgaaccttctgggaagcagaggcggagaggaggtgctcaacagagccttcaagaagctg
ctctgggcttcttgccacgcgggcgacacgcctatgatcaattttgacttccatcagttt
gccaaaggtgggaagctagagaaattggagaccctcttgaggccacagttaaagctgcac
tgggaagacttcgatgtgttcacaaagggggagaacgtcagtccacgttttcagaaaggc
actttgcggatgaactgtcttgactgcctggaccgaaccaacactgtgcagagcttcatc
gcgctcgaggtcctgcatctgcagctcaagaccctggggctgagttcaaaacccatcgtt
gaccgctttgtggagtccttcaaagccatgtggtctctgaatggccacagcctgagcaag
gtgttcacaggcagcagagccctggaagggaaggccaaggtggggaagctgaaggatgga
gcccggtccatgtctcgaaccatccagtccaacttcttcgacggggtgaagcaggaggcc
atcaagctgctgctggttggggacgtctacggcgaggaggtggcagacaaagggggcatg
ctgctggacagcacggcgctcctggtgactcccaggatcctgaaagctatgactgagcgt
cagtccgaattcacaaatttcaagcggatccggattgctatggggacctggaacgtgaac
ggaggaaagcagttccggagcaacgtgctcaggacggcggagctgacagactggctgctc
gactcgccccagctctcgggagctaccgactcccaggatgacagcagcccagctgacata
tttgctgtggggtttgaagagatggtggaattgagcgcagggaatattgtcaatgccagt
actaccaacaagaagatgtggggtgaacagcttcagaaagccatctcacgctctcataga
tacattctgttgacttcggcacagctggtgggcgtctgtctttatatctttgtacgtcca
taccatgtcccgttcatcagggacgtagccatcgacacagtgaagacgggcatggggggc
aaggcggggaacaagggcgccgtcggcatccgcttccagttccacagcaccagcttctgc
ttcatatgtagtcacctgacggccgggcagtcccaggtgaaggagcggaatgaagactac
aaggagatcacccagaaactctgcttcccaatggggagaaatgttttttctcatgattat
gtattttggtgtggcgatttcaactaccgcattgatcttacttatgaagaagtcttctat
tttgttaaacgccaagactggaagaaacttctggaatttgatcaactacagctacagaaa
tcaagtggaaaaatttttaaggactttcacgaaggagccattaactttggacccacctac
aagtatgacgttggctcagccgcctacgatacaagcgacaaatgccgcacccccgcctgg
acagacagggtgctgtggtggaggaagaaacatccctttgataaaacagctggagaactc
aaccttctagacagtgatctagatgttgacaccaaagtcagacacacctggtctcctggt
gccctgcagtattatggtcgtgcggagctacaagcgtctgatcacagacctgtgctggcg
atcgtggaggtggaagttcaggaagtcgatgtgggtgctcgggagagggttttccaggaa
gtgtcctccttccagggccccctggatgccactgttgtagtaaaccttcaatcaccgacc
ttagaagagaaaaacgagtttccagaggacctgcgtactgagctcatgcagaccttgggg
agttatgggacaattgttcttgtcaggatcaaccaagggcagatgctggtaacttttgca
gacagtcactcggctctcagtgtcctggacgtggacggtatgaaggtgaaaggcagagca
gtgaagattagaccgaagaccaaggactggctgaaaggtttgcgagaggagatcattcgg
aaacgagacagcatggcccccgtgtctcccactgccaactcctgtttgctggaggaaaac
tttgacttcacaagtttggactatgagtcagaaggggatattcttgaagacgatgaagac
tacttggtggatgaattcaatcagcctggagtctcggacagtgaactcgggggagacgac
ctctctgatgtccccggccccacagcactggctcctcccagcaagtcacctgctctcacc
aaaaagaagcagcatccaacgtacaaagatgacgcggacctggtggagctcaagcgggag
ctggaagccgtcggggagttccgccaccgttctccgagcaggtctctgtcggtccccaac
cggcctcggccacctcaacccccgcagagacccccccctccaaccggtttaatggtgaaa
aagtcggcttcagatgcgtccatctcctccggcacccatggacagtattcaattttgcag
acggcaagacttctaccaggagcacctcagcaacctcccaaggctcggactggaataagt
aaaccttataatgtcaagcagatcaaaaccaccaatgcccaggaggcagaagcagcaatc
cggtgtctcctggaagccagaggaggtgcctccgaagaagccctaagtgccgtggcccca
agggaccttgaagcatcctctgaaccagagcccacaccgggggcagccaaaccagagacc
ccacaggcgcccccactccttccccgtcggcccccacccagagttcctgccatcaagaag
ccaaccttgagaaggacaggaaagcccctgtcaccggaagaacagtttgagcaacagact
gtccattttacaatcgggcccccggagacaagcgttgaggcccctcctgtcgtgacagcc
cctcgagtccctcctgttcccaaaccaagaacatttcagcctgggaaagctgcagagagg
ccaagccacaggaagccagcatcagacgaagcccctcctggggcaggagcctctgtgcca
ccacctctggaggcgccgcctcttgtgcccaaggtacccccgaggaggaagaagtcagcc
cccgcagccttccacctgcaggtcctgcagagcaacagccagcttctccagggcctcact
tacaatagcagtgacagcccctctgggcacccacctgccgcgggcaccgtcttcccacaa
ggggactttctcagcacttcatctgctacaagccccgacagcgatggcaccaaagcgatg
aagccagaggcagccccacttcttggtgattatcaggaccccttctggaaccttcttcac
caccctaaactgttgaataacacttggctttctaagagctcagaccctttggactcagga
accaggagccccaaaagagatcccatagacccagtgtcagctggcgcttcagctgccaag
gcagagctgccaccagatcatgaacacaaaaccttaggtcactgggtgacaatcagtgac
caagaaaagaggacagcactgcaggtgtttgacccactggcaaaaacatga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (9)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (7)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (3)   
   PROSITE (3)   
All databases (41)

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