KEGG H.sapiens: 9060

Homo sapiens (human): 9060

Entry

9060 CDS H.sapiens

Gene name PAPSS2

Definition 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (EC:2.7.1.25
2.7.7.4)

Orthology K00860 adenylylsulfate kinase [EC:2.7.1.25]
K00958 sulfate adenylyltransferase [EC:2.7.7.4]

Pathway hsa00230 Purine metabolism
hsa00450 Selenoamino acid metabolism
hsa00920 Sulfur metabolism
hsa01100 Metabolic pathways

Class Metabolism; Energy Metabolism; Sulfur metabolism [PATH:hsa00920]
Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:hsa00230]
Metabolism; Metabolism of Other Amino Acids; Selenoamino acid
metabolism [PATH:hsa00450]

SSDB

Motif Pfam: ATP-sulfurylase APS_kinase DUF74

Other DBs NCBI-GI: 62912492
NCBI-GeneID: 9060
OMIM: 603005
HGNC: 8604
HPRD: 04303
Ensembl: ENSG00000198682
UniProt: O95340

Structure

PDB: 2AX4

Position 10q23-q24

AA seq 619 aa
MSGIKKQKTENQQKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISF
ALEEYLVSHAIPCYSLDGDNVRHGLNRNLGFSPGDREENIRRIAEVAKLFADAGLVCITS
FISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDS
DYEKPETPERVLKTNLSTVSDCVHQVVELLQEQNIVPYTIIKDIHELFVPENKLDHVRAE
AETLPSLSITKLDLQWVQVLSEGWATPLKGFMREKEYLQVMHFDTLLDGMALPDGVINMS
IPIVLPVSAEDKTRLEGCSKFVLAHGGRRVAILRDAEFYEHRKEERCSRVWGTTCTKHPH
IKMVMESGDWLVGGDLQVLEKIRWNDGLDQYRLTPLELKQKCKEMNADAVFAFQLRNPVH
NGHALLMQDTRRRLLERGYKHPVLLLHPLGGWTKDDDVPLDWRMKQHAAVLEEGVLDPKS
TIVAIFPSPMLYAGPTEVQWHCRSRMIAGANFYIVGRDPAGMPHPETKKDLYEPTHGGKV
LSMAPGLTSVEIIPFRVAAYNKAKKAMDFYDPARHNEFDFISGTRMRKLAREGENPPDGF
MAPKAWKVLTDYYRSLEKN

NT seq 1860 nt +upstreamnt +downstreamnt
atgtcggggatcaagaagcaaaagacggagaaccagcagaaatccaccaatgtagtctat
caggcccaccatgtgagcaggaataagagagggcaagtggttggaacaaggggtgggttc
cgaggatgtaccgtgtggctaacaggtctctctggtgctggaaaaacaacgataagtttt
gccctggaggagtaccttgtctcccatgccatcccttgttactccctggatggggacaat
gtccgtcatggccttaacagaaatctcggattctctcctggggacagagaggaaaatatc
cgccggattgctgaggtggctaagctgtttgctgatgctggtctggtctgcattaccagc
tttatttctccattcgcaaaggatcgtgagaatgcccgcaaaatacatgaatcagcaggg
ctgccattctttgaaatatttgtagatgcacctctaaatatttgtgaaagcagagacgta
aaaggcctctataaaagggccagagctggggagattaaaggatttacaggtattgattct
gattatgagaaacctgaaactcctgagcgtgtgcttaaaaccaatttgtccacagtgagt
gactgtgtccaccaggtagtggaacttctgcaagagcagaacattgtaccctatactata
atcaaagatatccacgaactctttgtgccggaaaacaaacttgaccacgtccgagctgag
gctgaaactctcccttcattatcaattactaagctggatctccagtgggtccaggttttg
agcgaaggctgggccactcccctcaaaggtttcatgcgggagaaggagtacttacaggtt
atgcactttgacaccctgctagatggcatggcccttcctgatggcgtgatcaacatgagc
atccccattgtactgcccgtctctgcagaggataagacacggctggaagggtgcagcaag
tttgtcctggcacatggtggacggagggtagctatcttacgagacgctgaattctatgaa
cacagaaaagaggaacgctgttcccgtgtttgggggacaacatgtacaaaacacccccat
atcaaaatggtgatggaaagtggggactggctggttggtggagaccttcaggtgctggag
aaaataagatggaatgatgggctggaccaataccgtctgacacctctggagctcaaacag
aaatgtaaagaaatgaatgctgatgcggtgtttgcattccagttgcgcaatcctgtccac
aatggccatgccctgttgatgcaggacactcgccgcaggctcctagagaggggctacaag
cacccggtcctcctactacaccctctgggcggctggaccaaggatgacgatgtgcctcta
gactggcggatgaagcagcacgcggctgtgctcgaggaaggggtcctggatcccaagtca
accattgttgccatctttccgtctcccatgttatatgctggccccacagaggtccagtgg
cactgcaggtcccggatgattgcgggtgccaatttctacattgtggggagggaccctgca
ggaatgccccatcctgaaaccaagaaggatctgtatgaacccactcatgggggcaaggtc
ttgagcatggcccctggcctcacctctgtggaaatcattccattccgagtggctgcctac
aacaaagccaaaaaagccatggacttctatgatccagcaaggcacaatgagtttgacttc
atctcaggaactcgaatgaggaagctcgcccgggaaggagagaatcccccagatggcttc
atggcccccaaagcatggaaggtcctgacagattattacaggtccctggagaagaactaa

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (2)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (2)   
   IPI (4)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (58)

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