KEGG   Homo sapiens (human): 9061Help
Entry
9061              CDS       H.sapiens                              
Gene name PAPSS1
Definition 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (EC:2.7.1.25
2.7.7.4)
Orthology K00860  adenylylsulfate kinase [EC:2.7.1.25]
K00958  sulfate adenylyltransferase [EC:2.7.7.4]
Pathway hsa00230  Purine metabolism
hsa00450  Selenoamino acid metabolism
hsa00920  Sulfur metabolism
hsa01100  Metabolic pathways
Class Metabolism; Energy Metabolism; Sulfur metabolism [PATH:hsa00920]
Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:hsa00230]
Metabolism; Metabolism of Other Amino Acids; Selenoamino acid
metabolism [PATH:hsa00450]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: ATP-sulfurylase APS_kinase Thymidylate_kin KTI12 Zeta_toxin
      6PF2K
Motif
Other DBs NCBI-GI: 46094058
NCBI-GeneID: 9061
OMIM: 603262
HGNC: 8603
HPRD: 09132
Ensembl: ENSG00000138801
UniProt: O43252 Q6IAX6
Structure
PDB: 2PEZ 1X6V 2PEY 2OFX 1XNJ 2OFW 1XJQ 2QJF
     
     Thumbnails

Jmol
Position 4q24
AA seq 624 aa AA seqDB search
MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGL
SGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLF
ADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAG
EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVP
ENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG
VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTC
KNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQL
RNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGV
LNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPS
HGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQK
PPEGFMAPKAWTVLTEYYKSLEKA
NT seq 1875 nt NT seq  +upstreamnt  +downstreamnt
atggagatccccgggagcctgtgcaagaaagtcaaactgagcaataacgcgcagaactgg
ggaatgcagagagcaaccaatgtcacctaccaagcccatcatgtcagcaggaacaagaga
ggtcaggtggtggggaccagaggtggctttcgtggttgcacagtttggctaacaggcttg
tctggagcgggaaagactactgtgagcatggccttggaggagtacctggtttgtcatggt
attccatgctacactctggatggtgacaatattcgtcaaggtctcaataaaaatcttggc
tttagtcctgaagacagagaagagaatgttcgacgcatcgcagaagttgctaaactgttt
gcagatgctggcttagtgtgcatcacaagtttcatatcaccttacactcaggatcgcaac
aatgcaaggcaaattcatgaaggtgcaagtttaccgttttttgaagtatttgttgatgct
cctctgcatgtttgtgaacagagggatgtcaaaggactctacaaaaaagcccgggcagga
gaaattaaaggtttcactgggatcgattctgaatatgaaaagccagaggcccctgagttg
gtgctgaaaacagactcctgtgatgtaaatgactgtgtccagcaagttgtggaacttcta
caggaacgggatattgtacctgtggatgcatcttatgaagtaaaagaactatatgtgcca
gaaaataaacttcatttggcaaaaacagatgcggaaacattaccagcactgaaaattaat
aaagtggatatgcagtgggtgcaggttttggcagaaggttgggcaaccccattgaatggc
tttatgagagagagggagtacttgcagtgccttcattttgattgtcttctggatggaggt
gtcattaacttgtcagtacctatagttctgactgcgactcatgaagataaagagaggctg
gacggctgtacagcatttgctctgatgtatgagggccgccgtgtggccattcttcgcaat
ccagagttttttgagcacaggaaagaggagcgctgtgccagacagtggggaacgacatgc
aagaaccacccctatattaagatggtgatggaacaaggagattggctgattggaggagat
cttcaagtcttggatcgagtttattggaatgatggtcttgatcagtatcgtcttactcct
actgagctaaagcagaaatttaaagatatgaatgctgatgctgtctttgcatttcaacta
cgcaacccagtgcacaatggacatgccctgttaatgcaggatacccataagcaacttcta
gagaggggctaccggcgccctgtcctcctcctccaccctctgggtggctggacaaaggat
gacgatgttcctttgatgtggcgtatgaagcagcatgctgcagtgttggaggaaggagtt
ctgaatcctgagacgacagtggtggccatcttcccatctcccatgatgtatgctggacca
actgaggtccagtggcattgcagagcacggatggttgcaggagccaacttttacattgtt
ggacgagaccctgctggcatgcctcatccagaaacagggaaggatctttatgagccaagt
catggtgccaaagtgctgacgatggcccctggtttaatcactttggaaatagttcccttt
cgagttgcagcttacaacaagaaaaagaagcgtatggactactatgactctgaacaccat
gaagactttgaatttatttcaggaacacgaatgcgcaaacttgctcgagaaggccagaaa
ccacctgaaggtttcatggctcccaaggcttggaccgtgctgacagaatactacaaatcc
ttggagaaagcttag
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