KEGG T01001: APOE

Homo sapiens (human): 348

Entry

348 CDS T01001

Gene name

APOE, AD2, LDLCQ5, LPG

Definition

apolipoprotein E

Orthology

K04524

apolipoprotein E

Organism

hsa Homo sapiens (human)

Pathway

hsa05010

Alzheimer's disease

Disease

H00056	Alzheimer's disease (AD)
H00156	Hyperlipoproteinemia, type III
H00887	Lipoprotein glomerulopathy
H01168	Sea-blue histiocyte disease

Class

Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:hsa05010]

SSDB

Motif

Pfam:

Apolipoprotein Prominin Apo-CIII Syntaxin_2 ApoLp-III Bacillus_HBL Hemerythrin LEDGF DUF1043 OmpH DUF773

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

1OR3 1NFN 1BZ4 1EA8 1B68 1NFO 1LPE 1OR2 1LE4 1LE2 2L7B 2KC3 1GS9 1H7I 1OEF 1OEG

Position

19q13.2

AA seq 317 aa
MKVLWAALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQT
LSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQA
RLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVY
QAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMG
SRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEK
VQAAVGTSAAPVPSDNH

NT seq 954 nt +upstreamnt +downstreamnt
atgaaggttctgtgggctgcgttgctggtcacattcctggcaggatgccaggccaaggtg
gagcaagcggtggagacagagccggagcccgagctgcgccagcagaccgagtggcagagc
ggccagcgctgggaactggcactgggtcgcttttgggattacctgcgctgggtgcagaca
ctgtctgagcaggtgcaggaggagctgctcagctcccaggtcacccaggaactgagggcg
ctgatggacgagaccatgaaggagttgaaggcctacaaatcggaactggaggaacaactg
accccggtggcggaggagacgcgggcacggctgtccaaggagctgcaggcggcgcaggcc
cggctgggcgcggacatggaggacgtgtgcggccgcctggtgcagtaccgcggcgaggtg
caggccatgctcggccagagcaccgaggagctgcgggtgcgcctcgcctcccacctgcgc
aagctgcgtaagcggctcctccgcgatgccgatgacctgcagaagcgcctggcagtgtac
caggccggggcccgcgagggcgccgagcgcggcctcagcgccatccgcgagcgcctgggg
cccctggtggaacagggccgcgtgcgggccgccactgtgggctccctggccggccagccg
ctacaggagcgggcccaggcctggggcgagcggctgcgcgcgcggatggaggagatgggc
agccggacccgcgaccgcctggacgaggtgaaggagcaggtggcggaggtgcgcgccaag
ctggaggagcaggcccagcagatacgcctgcaggccgaggccttccaggcccgcctcaag
agctggttcgagcccctggtggaagacatgcagcgccagtgggccgggctggtggagaag
gtgcaggctgccgtgggcaccagcgccgcccctgtgcccagcgacaatcactga

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (9)   
   KEGG DISEASE (4)   
   OMIM (5)   
Drug (2)   
   KEGG DRUG (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
3D Structure (16)   
   PDB (16)   
Protein domain (11)   
   Pfam (11)   
All databases (79)   

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