KEGG T01001: B4GALT1

Homo sapiens (human): 2683

Entry

2683 CDS T01001

Gene name

B4GALT1, B4GAL-T1, CDG2D, GGTB2, GT1, GTB, beta4Gal-T1

Definition

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (EC:2.4.1.22 2.4.1.90 2.4.1.38)

Orthology

K07966

beta-1,4-galactosyltransferase 1 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]

Organism

hsa Homo sapiens (human)

Pathway

hsa00052	Galactose metabolism
hsa00510	N-Glycan biosynthesis
hsa00514	Other types of O-glycan biosynthesis
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series
hsa01100	Metabolic pathways

Module

hsa_M00071	Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer
hsa_M00075	N-glycan biosynthesis, complex type

Disease

H00119

Congenital disorders of glycosylation (CDG) type II

Class

Metabolism; Carbohydrate metabolism; Galactose metabolism [PATH:hsa00052]
Metabolism; Glycan biosynthesis and metabolism; N-Glycan biosynthesis [PATH:hsa00510]
Metabolism; Glycan biosynthesis and metabolism; Other types of O-glycan biosynthesis [PATH:hsa00514]
Metabolism; Glycan biosynthesis and metabolism; Glycosaminoglycan biosynthesis - keratan sulfate [PATH:hsa00533]
Metabolism; Glycan biosynthesis and metabolism; Glycosphingolipid biosynthesis - lacto and neolacto series [PATH:hsa00601]

SSDB

Motif

Pfam:

Glyco_transf_7N Glyco_transf_7C Glyco_tranf_2_2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2FY7 2FYA 2FYB 2AGD 4EE4 4EEA 2AH9 2AES 2AEC 2AE7 4EE5 4EEG 4EEM 3EE5 4EE3 4EEO

Position

9p13

AA seq 398 aa
MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPL
QGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVP
HTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAI
IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYD
YTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLTI
NGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIA
HTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS

NT seq 1197 nt +upstreamnt +downstreamnt
atgaggcttcgggagccgctcctgagcggcagcgccgcgatgccaggcgcgtccctacag
cgggcctgccgcctgctcgtggccgtctgcgctctgcaccttggcgtcaccctcgtttac
tacctggctggccgcgacctgagccgcctgccccaactggtcggagtctccacaccgctg
cagggcggctcgaacagtgccgccgccatcgggcagtcctccggggagctccggaccgga
ggggcccggccgccgcctcctctaggcgcctcctcccagccgcgcccgggtggcgactcc
agcccagtcgtggattctggccctggccccgctagcaacttgacctcggtcccagtgccc
cacaccaccgcactgtcgctgcccgcctgccctgaggagtccccgctgcttgtgggcccc
atgctgattgagtttaacatgcctgtggacctggagctcgtggcaaagcagaacccaaat
gtgaagatgggcggccgctatgcccccagggactgcgtctctcctcacaaggtggccatc
atcattccattccgcaaccggcaggagcacctcaagtactggctatattatttgcaccca
gtcctgcagcgccagcagctggactatggcatctatgttatcaaccaggcgggagacact
atattcaatcgtgctaagctcctcaatgttggctttcaagaagccttgaaggactatgac
tacacctgctttgtgtttagtgacgtggacctcattccaatgaatgaccataatgcgtac
aggtgtttttcacagccacggcacatttccgttgcaatggataagtttggattcagccta
ccttatgttcagtattttggaggtgtctctgctctaagtaaacaacagtttctaaccatc
aatggatttcctaataattattggggctggggaggagaagatgatgacatttttaacaga
ttagtttttagaggcatgtctatatctcgcccaaatgctgtggtcgggaggtgtcgcatg
atccgccactcaagagacaagaaaaatgaacccaatcctcagaggtttgaccgaattgca
cacacaaaggagacaatgctctctgatggtttgaactcactcacctaccaggtgctggat
gtacagagatacccattgtatacccaaatcacagtggacatcgggacaccgagctag

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (9)   
   KEGG ENZYME (3)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (18)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (41)   
   RefSeq(nuc) (1)   
   GenBank (20)   
   EMBL (20)   
3D Structure (16)   
   PDB (16)   
Protein domain (3)   
   Pfam (3)   
All databases (114)   

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