KEGG   Homo sapiens (human): 4121Help
Entry
4121              CDS       T01001                                 

Gene name
MAN1A1, HUMM3, HUMM9, MAN9
Definition
mannosidase, alpha, class 1A, member 1 (EC:3.2.1.113)
Orthology
K01230  
mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
Organism
hsa  Homo sapiens (human)
Pathway
N-Glycan biosynthesis
Metabolic pathways
Protein processing in endoplasmic reticulum
Module
N-glycan precursor trimming
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    4121 (MAN1A1)
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    4121 (MAN1A1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.113  mannosyl-oligosaccharide 1,2-alpha-mannosidase
     4121 (MAN1A1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
6q22
AA seq 653 aa AA seqDB search
MPVGGLLPLFSSPAGGVLGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIF
FLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPEAALEDN
LARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPI
GVESREPADAAIREKRAKIKEMMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGAT
IVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEI
FRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHL
SHLSGNPIFAEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLL
KAWLMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGG
MFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEK
YYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDD
VQQSFFLAETLKYLYLIFSDDDLLPLEHWIFNSEAHLLPILPKDKKEVEIREE
NT seq 1962 nt NT seq  +upstreamnt  +downstreamnt
atgcccgtggggggcctgttgccgctcttcagcagccccgcgggcggcgtcctgggcggg
gggctcggcggcggcggtggcaggaaggggtcgggccccgccgccctccgcctgacggag
aagttcgtgctgctgctggtattcagcgccttcatcacgctctgcttcggggcgatcttc
ttcctgccagactcctccaagctgctcagcggggtcctgttccactccagccccgccttg
cagccggccgccgaccacaagcccgggcccggggcgcgcgccgaggacgcggccgagggg
cgagcccggcgccgcgaggagggggcacccggggacccggaggccgccctggaggacaac
ttggccaggatccgcgaaaaccacgagcgggctctcagggaagccaaggagaccctgcag
aagctgcccgaggagatccaaagagacatcctactggagaagaagaaggtggcccaggac
cagctgcgtgacaaggcgccgttcagaggcctgcccccggtggacttcgtgcccccaatc
ggggtggagagccgggagcccgccgacgccgccatccgcgagaaaagggcaaagatcaaa
gagatgatgaaacatgcttggaataattataaaggttatgcctggggattaaatgaactc
aaacctatatcaaaaggaggccattcaagcagtttgtttggtaacatcaaaggagcaact
atagtagatgccctggatacactttttattatggaaatgaaacatgaatttgaagaagca
aaatcatgggttgaagaaaatttagattttaatgtgaatgctgaaatttctgtctttgaa
gtaaatatacgctttgttggtggactactctcagcctactatctgtctggagaagagatt
tttcgaaagaaagcagtggaacttggggtaaaattgctacctgcatttcatactccctct
ggaataccttgggcattgctgaatatgaaaagtggtattggaaggaactggccctgggcc
tctggaggcagcagtattctggcagaatttggaaccctgcatttggagtttatgcacttg
agccacttatcaggaaaccccatctttgctgaaaaggtaatgaatattcgaacagtactg
aacaaactggaaaaaccacaaggcctttatcctaactatctgaatcccagtagtggacag
tggggtcaacatcatgtatcagttggaggacttggagacagcttctatgagtatttgctg
aaggcctggttaatgtctgacaagacagatctggaagctaagaagatgtattttgatgct
gttcaggctatcgagactcatttgatccgcaagtctagcagcggactaacttatatcgca
gagtggaaagggggcctcctggagcacaagatgggccacctgacctgcttcgcggggggc
atgttcgcactcggggctgatgcagctcccgaaggcatggcccaacactaccttgaactc
ggggctgaaattgcccgtacttgtcatgaatcatataatcgaacatttatgaaactggga
ccagaagctttcagatttgatggtggtgttgaagccatcgctacaagacaaaatgaaaaa
tactacatcttacggccagaagttatggagacttacatgtatatgtggagactgactcat
gatccaaagtacaggaaatgggcctgggaagccgtagaggccttggaaaaccattgcaga
gtgaatggaggctattcaggcctaagggatgtttaccttcttcatgagagttatgatgat
gtgcagcagagtttcttcctggcagagacattgaaatatttgtacctaatattttctgac
gacgatcttcttccactggagcattggatcttcaatagcgaggcacatcttctccctatc
ctccctaaagataaaaaggaagttgaaatcagagaggaataa

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