KEGG   Homo sapiens (human): 10905Help
Entry
10905             CDS       T01001                                 

Gene name
MAN1A2, MAN1B
Definition
mannosidase, alpha, class 1A, member 2 (EC:3.2.1.113)
Orthology
K01230  
mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
Organism
hsa  Homo sapiens (human)
Pathway
N-Glycan biosynthesis
Metabolic pathways
Protein processing in endoplasmic reticulum
Module
N-glycan precursor trimming
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    10905 (MAN1A2)
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    10905 (MAN1A2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.113  mannosyl-oligosaccharide 1,2-alpha-mannosidase
     10905 (MAN1A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
UniProt: 
Position
1p13
AA seq 641 aa AA seqDB search
MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDS
SKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDEHRHREEEERLRNKIRADHEKALE
EAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK
REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH
DEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLP
AFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVM
HIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEAR
KMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKA
GHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWY
LWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYL
YLLFSGDDLLPLDHWVFNTEAHPLPVLHLANTTLSGNPAVR
NT seq 1926 nt NT seq  +upstreamnt  +downstreamnt
atgactaccccagccctgctgcccctctctggacgtaggataccacctctgaacctgggg
ccgccttccttcccacatcacagggctaccttgagactttctgagaagtttattcttctc
cttattcttagtgccttcatcactctgtgttttggggcattctttttccttccagactct
tcaaaacacaaacgctttgatttgggtttagaagatgtgttaattccacatgtagatgcc
ggtaaaggggctaaaaaccccggagtcttcctgatccatggacccgatgaacatagacac
agggaagaggaagaacgtctgagaaataaaattcgagctgatcatgagaaggccttggaa
gaagcaaaagaaaaattaagaaagtcaagagaggaaattcgagcagaaattcagacagag
aaaaataaggtagtccaagaaatgaagataaaagagaacaagccactgccaccagtccct
attcccaaccttgtaggaatacgtggtggagacccagaagataatgacataagagagaaa
agggaaaaaattaaagagatgatgaaacatgcttgggataactataggacatatgggtgg
ggacataatgaactcagacctattgcaaggaaaggacactcccctaacatatttggaagt
tcacaaatgggtgctaccatagtagatgctttggataccctttatatcatgggacttcat
gatgaattcctagatgggcaaagatggattgaagacaaccttgatttcagtgtgaattca
gaggtgtctgtgtttgaagtcaacattcgatttattggaggcctacttgcagcatattac
ctatcaggagaggagatattcaagattaaagcagtgcaattggctgagaaactccttcct
gcctttaacacacctactgggattccttgggcaatggtgaatttgaaaagtggagtaggg
cgaaactggggctgggcatctgcaggtagcagcattctggctgaatttggtacactacat
atggagttcatccacctcagctacttgacaggggacctgacttactacaaaaaggttatg
cacattcggaaactacttcagaaaatggatcgtccaaatggtctttatccaaattatttg
aaccccagaacagggcgctggggtcagtatcatacatctgtcggtggcctgggagacagt
ttttatgaatacttactgaaagcatggttgatgtcagataaaacagaccatgaggcaaga
aagatgtatgatgatgctattgaggctatagaaaaacatcttattaagaagtctcgtgga
ggtcttacctttattggagaatggaagaatgggcacttggaaaaaaagatggggcatttg
gcctgctttgctgggggaatgtttgcactaggagcagatggttccagagcagataaagct
ggtcattatttagagctaggggcagaaattgcacgtacttgtcatgagtcatatgacaga
actgcattaaagctaggtcctgaatcattcaagtttgatggtgcagtggaggctgtggct
gtccggcaggctgaaaagtattatatcctccgtccagaagtaattgaaacctattggtac
ctatggcgattcactcacgatccaagatacaggcagtggggctgggaagcagcactggcc
attgaaaagtattgccgagttaatggtgggttttctggagtcaaagatgtatattcctct
actcctacacatgatgatgtacagcagagcttttttcttgctgaaacattaaaatatttg
tatctgctgttctccggtgatgaccttttacctttagaccactgggtgtttaatacagag
gctcaccctctgcctgtgttacatttagccaacaccacactttcaggtaatcctgctgtt
cgatga

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