KEGG   Homo sapiens (human): 11253Help
Entry
11253             CDS       T01001                                 

Gene name
MAN1B1, ERMAN1, MANA-ER, MRT15
Definition
mannosidase, alpha, class 1B, member 1 (EC:3.2.1.113)
Orthology
K01230  
mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
Organism
hsa  Homo sapiens (human)
Pathway
N-Glycan biosynthesis
Metabolic pathways
Protein processing in endoplasmic reticulum
Module
N-glycan precursor trimming
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    11253 (MAN1B1)
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    11253 (MAN1B1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.113  mannosyl-oligosaccharide 1,2-alpha-mannosidase
     11253 (MAN1B1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
9q34
AA seq 699 aa AA seqDB search
MAACEGRRSGALGSSQSDFLTPPVGGAPWAVATTVVMYPPPPPPPHRDFISVTLSFGENY
DNSKSWRRRSCWRKWKQLSRLQRNMILFLLAFLLFCGLLFYINLADHWKALAFRLEEEQK
MRPEIAGLKPANPPVLPAPQKADTDPENLPEISSQKTQRHIQRGPPHLQIRPPSQDLKDG
TQEEATKRQEAPVDPRPEGDPQRTVISWRGAVIEPEQGTELPSRRAEVPTKPPLPPARTQ
GTPVHLNYRQKGVIDVFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMWI
LGLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSGDSLFLRKAEDFGN
RLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEA
VEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQE
TQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFLPGTLALGVYHG
LPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPET
VESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFF
LGETLKYLFLLFSDDPNLLSLDAYVFNTEAHPLPIWTPA
NT seq 2100 nt NT seq  +upstreamnt  +downstreamnt
atggctgcctgcgagggcaggagaagcggagctctcggttcctctcagtcggacttcctg
acgccgccagtgggcggggccccttgggccgtcgccaccactgtagtcatgtacccaccg
ccgccgccgccgcctcatcgggacttcatctcggtgacgctgagctttggcgagaactat
gacaacagcaagagttggcggcggcgctcgtgctggaggaaatggaagcaactgtcgaga
ttgcagcggaatatgattctcttcctccttgcctttctgcttttctgtggactcctcttc
tacatcaacttggctgaccattggaaagctctggctttcaggctagaggaagagcagaag
atgaggccagaaattgctgggttaaaaccagcaaatccacccgtcttaccagctcctcag
aaggcggacaccgaccctgagaacttacctgagatttcgtcacagaagacacaaagacac
atccagcggggaccacctcacctgcagattagacccccaagccaagacctgaaggatggg
acccaggaggaggccacaaaaaggcaagaagcccctgtggatccccgcccggaaggagat
ccgcagaggacagtcatcagctggaggggagcggtgatcgagcctgagcagggcaccgag
ctcccttcaagaagagcagaagtgcccaccaagcctcccctgccaccggccaggacacag
ggcacaccagtgcatctgaactatcgccagaagggcgtgattgacgtcttcctgcatgca
tggaaaggataccgcaagtttgcatggggccatgacgagctgaagcctgtgtccaggtcc
ttcagtgagtggtttggcctcggtctcacactgatcgacgcgctggacaccatgtggatc
ttgggtctgaggaaagaatttgaggaagccaggaagtgggtgtcgaagaagttacacttt
gaaaaggacgtggacgtcaacctgtttgagagcacgatccgcatcctgggggggctcctg
agtgcctaccacctgtctggggacagcctcttcctgaggaaagctgaggattttggaaat
cggctaatgcctgccttcagaacaccatccaagattccttactcggatgtgaacatcggt
actggagttgcccacccgccacggtggacctccgacagcactgtggccgaggtgaccagc
attcagctggagttccgggagctctcccgtctcacaggggataagaagtttcaggaggca
gtggagaaggtgacacagcacatccacggcctgtctgggaagaaggatgggctggtgccc
atgttcatcaatacccacagtggcctcttcacccacctgggcgtattcacgctgggcgcc
agggccgacagctactatgagtacctgctgaagcagtggatccagggcgggaagcaggag
acacagctgctggaagactacgtggaagccatcgagggtgtcagaacgcacctgctgcgg
cactccgagcccagtaagctcacctttgtgggggagcttgcccacggccgcttcagtgcc
aagatggaccacctggtgtgcttcctgccagggacgctggctctgggcgtctaccacggc
ctgcccgccagccacatggagctggcccaggagctcatggagacttgttaccagatgaac
cggcagatggagacggggctgagtcccgagatcgtgcacttcaacctttacccccagccg
ggccgtcgggacgtggaggtcaagccagcagacaggcacaacctgctgcggccagagacc
gtggagagcctgttctacctgtaccgcgtcacaggggaccgcaaataccaggactggggc
tgggagattctgcagagcttcagccgattcacacgggtcccctcgggtggctattcttcc
atcaacaatgtccaggatcctcagaagcccgagcctagggacaagatggagagcttcttc
ctgggggagacgctcaagtatctgttcttgctcttctccgatgacccaaacctgctcagc
ctggatgcctacgtgttcaacaccgaagcccaccctctgcctatctggacccctgcctag

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