| Entry |
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| Gene name |
PIGA, GPI3, MCAHS2, PIG-A
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| Definition |
phosphatidylinositol glycan anchor biosynthesis, class A (EC:2.4.1.198)
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| Orthology |
| phosphatidylinositol glycan, class A [EC: 2.4.1.198] |
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| Organism |
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| Pathway |
| Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | | Metabolic pathways |
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| Module |
| GPI-anchor biosynthesis, core oligosaccharide |
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| Disease |
| Paroxysmal nocturnal hemoglobinuria (PNH) |
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| Class |
Metabolism; Glycan biosynthesis and metabolism; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis [PATH: hsa00563]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Position |
Xp22.1
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| AA seq |
484 aa  
MACRGGAGNGHRASATLSRVSPGSLYTCRTRTHNICMVSDFFYPNMGGVESHIYQLSQCL
IERGHKVIIVTHAYGNRKGIRYLTSGLKVYYLPLKVMYNQSTATTLFHSLPLLRYIFVRE
RVTIIHSHSSFSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNH
IICVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTPDPFRRHDSITIVVVSRLVYRKGI
DLLSGIIPELCQKYPDLNFIIGGEGPKRIILEEVRERYQLHDRVRLLGALEHKDVRNVLV
QGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGIPEVLPENLIILCEPSVKSLCEGLE
KAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEKVYDRVSVEAVLPMDKRLDRLISHC
GPVTGYIFALLAVFNFLFLIFLRWMTPDSIIDVAIDATGPRGAWTNNYSHSKRGGENNEI
SETR |
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| NT seq |
1455 nt  +upstreamnt +downstreamnt
atggcctgtagaggaggagctgggaatggccaccgtgcctcagctacactctctcgggtt
agccctggaagtctttacacatgtagaacccgtacccataatatatgcatggtatctgac
tttttctacccaaatatgggaggcgtggaaagccacatttaccagctctctcagtgcctg
attgaaagagggcataaggttataattgtcacccatgcttatggaaatcgaaaaggcatc
cgttacctcaccagtggcctcaaagtctattacttgcctctgaaagtcatgtacaaccag
tctacagccacgaccctctttcacagtctgccattgctcaggtacatatttgttcgggag
agagtcacgataatccattcacatagttctttttctgctatggcccatgatgctctcttc
cacgccaagacaatggggcttcagacagtcttcacggaccattccctttttggatttgct
gatgtcagctcggtgcttacaaacaagcttctaaccgtgtctctttgtgatacaaaccac
atcatttgtgtgtcttatactagtaaggaaaatactgtactaagagcagcactgaatcct
gaaatagtgtccgtcattcctaatgctgtagatcctactgacttcactccagacccattt
agaaggcatgatagtataactattgttgttgtcagcagacttgtttacagaaaagggatc
gatttgcttagtggtataatacctgaactctgtcagaaatatccagatttaaatttcata
attggaggagagggaccaaagagaatcattttggaagaagttcgggaaagataccagctg
catgacagggtgcgtcttttgggagctttagaacacaaggatgttagaaatgtcttagtt
caaggacatatttttctgaatacctcccttactgaagcattctgcatggcgatcgtggaa
gcagccagttgtggtttacaggttgtaagtaccagagttggtggaattcctgaggtgctt
ccagaaaaccttattattttatgtgagccttcagtaaaatctttgtgtgaaggattggaa
aaggctattttccaactgaagtcagggacattgccagctccagaaaacatccataacata
gtaaagactttctacacctggaggaatgttgcagaaagaactgaaaaggtatatgaccgg
gtatcagtggaagctgtgttgccaatggacaaacgactggacagacttatttctcactgc
ggcccagtaacaggctacatctttgctttgttggcagttttcaacttcctcttcctcatt
ttcttgagatggatgactccagattctatcattgatgttgcaatagatgccactgggcca
cggggtgcctggactaataactattctcacagtaaaagagggggtgagaataatgagata
tctgaaaccaggtag |
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