KEGG   PATHWAY: hsa00072Help
Entry
hsa00072                    Pathway                                

Name
Synthesis and degradation of ketone bodies - Homo sapiens (human)
Class
Metabolism; Lipid metabolism
BRITE hierarchy
Pathway map
Synthesis and degradation of ketone bodies
hsa00072

All organismsOrtholog table
Disease
H01076  
Alpha-methylacetoacetic aciduria
H01121  
Succinyl CoA:3-oxoacid CoA transferase (SCOT) deficiency
H01123  
HMG-CoA synthase (HMGCS) deficiency
Organism
Homo sapiens (human) [GN:hsa]
Gene
3157  
HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) [KO:K01641] [EC:2.3.3.10]
3158  
HMGCS2; 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) [KO:K01641] [EC:2.3.3.10]
3155  
HMGCL; 3-hydroxymethyl-3-methylglutaryl-CoA lyase [KO:K01640] [EC:4.1.3.4]
5019  
OXCT1; 3-oxoacid CoA transferase 1 [KO:K01027] [EC:2.8.3.5]
64064  
OXCT2; 3-oxoacid CoA transferase 2 [KO:K01027] [EC:2.8.3.5]
39  
ACAT2; acetyl-CoA acetyltransferase 2 [KO:K00626] [EC:2.3.1.9]
38  
ACAT1; acetyl-CoA acetyltransferase 1 [KO:K00626] [EC:2.3.1.9]
622  
BDH1; 3-hydroxybutyrate dehydrogenase, type 1 [KO:K00019] [EC:1.1.1.30]
56898  
BDH2; 3-hydroxybutyrate dehydrogenase, type 2 [KO:K00019] [EC:1.1.1.30]
Compound
C00024  
Acetyl-CoA
C00164  
Acetoacetate
C00207  
Acetone
C00332  
Acetoacetyl-CoA
C00356  
(S)-3-Hydroxy-3-methylglutaryl-CoA
C01089  
(R)-3-Hydroxybutanoate
KO pathway
 

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