KEGG PATHWAY: hsa00500

PATHWAY: hsa00500

Entry

hsa00500 Pathway

Name

Starch and sucrose metabolism - Homo sapiens (human)

Class

Metabolism; Carbohydrate metabolism

Pathway map

hsa00500

Starch and sucrose metabolism

Module

hsa_M00266	PTS system, maltose and glucose-specific II component [PATH:hsa00500]
hsa_M00269	PTS system, sucrose-specific II component [PATH:hsa00500]
hsa_M00270	PTS system, trehalose-specific II component [PATH:hsa00500]

Disease

H00069	Glycogen storage diseases (GSD)
H00115	Congenital sucrase-isomaltase deficiency
H01002	Generalized arterial calcification of infancy
H01193	Familial tumoral calcinosis (FTC)

Drug

D00216	Acarbose (JAN/USAN/INN)
D00625	Miglitol (JAN/USAN/INN)
D01665	Voglibose (JP16/USAN/INN)
D04537	Ingliforib (USAN/INN)

Other DBs

BSID:

82974

GO:

0005982 0005985

Organism

Homo sapiens (human) [GN:hsa]

Gene

8972	MGAM; maltase-glucoamylase (alpha-glucosidase) [KO:K12047] [EC:3.2.1.3 3.2.1.20]
2548	GAA; glucosidase, alpha [KO:K12316] [EC:3.2.1.20]
2595	GANC; glucosidase, alpha [KO:K12317] [EC:3.2.1.20]
6476	SI; sucrase-isomaltase (alpha-glucosidase) [KO:K01203] [EC:3.2.1.10 3.2.1.48]
57733	GBA3; glucosidase, beta, acid 3 (cytosolic) [KO:K05350] [EC:3.2.1.21]
11181	TREH; trehalase (brush-border membrane glycoprotein) [KO:K01194] [EC:3.2.1.28]
7358	UGDH; UDP-glucose 6-dehydrogenase [KO:K00012] [EC:1.1.1.22]
10941	UGT2A1; UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus [KO:K00699] [EC:2.4.1.17]
79799	UGT2A3; UDP glucuronosyltransferase 2 family, polypeptide A3 [KO:K00699] [EC:2.4.1.17]
7367	UGT2B17; UDP glucuronosyltransferase 2 family, polypeptide B17 [KO:K00699] [EC:2.4.1.17]
10720	UGT2B11; UDP glucuronosyltransferase 2 family, polypeptide B11 [KO:K00699] [EC:2.4.1.17]
54490	UGT2B28; UDP glucuronosyltransferase 2 family, polypeptide B28 [KO:K00699] [EC:2.4.1.17]
54578	UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 [KO:K00699] [EC:2.4.1.17]
54657	UGT1A4; UDP glucuronosyltransferase 1 family, polypeptide A4 [KO:K00699] [EC:2.4.1.17]
54658	UGT1A1; UDP glucuronosyltransferase 1 family, polypeptide A1 [KO:K00699] [EC:2.4.1.17]
54659	UGT1A3; UDP glucuronosyltransferase 1 family, polypeptide A3 [KO:K00699] [EC:2.4.1.17]
7365	UGT2B10; UDP glucuronosyltransferase 2 family, polypeptide B10 [KO:K00699] [EC:2.4.1.17]
54600	UGT1A9; UDP glucuronosyltransferase 1 family, polypeptide A9 [KO:K00699] [EC:2.4.1.17]
7364	UGT2B7; UDP glucuronosyltransferase 2 family, polypeptide B7 [KO:K00699] [EC:2.4.1.17]
54575	UGT1A10; UDP glucuronosyltransferase 1 family, polypeptide A10 [KO:K00699] [EC:2.4.1.17]
54576	UGT1A8; UDP glucuronosyltransferase 1 family, polypeptide A8 [KO:K00699] [EC:2.4.1.17]
54579	UGT1A5; UDP glucuronosyltransferase 1 family, polypeptide A5 [KO:K00699] [EC:2.4.1.17]
7366	UGT2B15; UDP glucuronosyltransferase 2 family, polypeptide B15 [KO:K00699] [EC:2.4.1.17]
54577	UGT1A7; UDP glucuronosyltransferase 1 family, polypeptide A7 [KO:K00699] [EC:2.4.1.17]
7363	UGT2B4; UDP glucuronosyltransferase 2 family, polypeptide B4 [KO:K00699] [EC:2.4.1.17]
574537	UGT2A2; UDP glucuronosyltransferase 2 family, polypeptide A2 [KO:K00699] [EC:2.4.1.17]
2990	GUSB; glucuronidase, beta [KO:K01195] [EC:3.2.1.31]
9365	KL; klotho [KO:K14756] [EC:3.2.1.31]
80146	UXS1; UDP-glucuronate decarboxylase 1 [KO:K08678] [EC:4.1.1.35]
7360	UGP2; UDP-glucose pyrophosphorylase 2 [KO:K00963] [EC:2.7.7.9]
5236	PGM1; phosphoglucomutase 1 [KO:K01835] [EC:5.4.2.2]
55276	PGM2; phosphoglucomutase 2 [KO:K15779] [EC:5.4.2.7 5.4.2.2]
3101	HK3; hexokinase 3 (white cell) [KO:K00844] [EC:2.7.1.1]
3098	HK1; hexokinase 1 [KO:K00844] [EC:2.7.1.1]
3099	HK2; hexokinase 2 [KO:K00844] [EC:2.7.1.1]
80201	HKDC1; hexokinase domain containing 1 [KO:K00844] [EC:2.7.1.1]
2645	GCK; glucokinase (hexokinase 4) [KO:K12407] [EC:2.7.1.2]
2538	G6PC; glucose-6-phosphatase, catalytic subunit [KO:K01084] [EC:3.1.3.9]
57818	G6PC2; glucose-6-phosphatase, catalytic, 2 [KO:K01084] [EC:3.1.3.9]
92579	G6PC3; glucose 6 phosphatase, catalytic, 3 [KO:K01084] [EC:3.1.3.9]
283209	PGM2L1; phosphoglucomutase 2-like 1 [KO:K11809] [EC:2.7.1.106]
2821	GPI; glucose-6-phosphate isomerase [KO:K01810] [EC:5.3.1.9]
2632	GBE1; glucan (1,4-alpha-), branching enzyme 1 [KO:K00700] [EC:2.4.1.18]
5836	PYGL; phosphorylase, glycogen, liver [KO:K00688] [EC:2.4.1.1]
5837	PYGM; phosphorylase, glycogen, muscle [KO:K00688] [EC:2.4.1.1]
5834	PYGB; phosphorylase, glycogen [KO:K00688] [EC:2.4.1.1]
2998	GYS2; glycogen synthase 2 (liver) [KO:K00693] [EC:2.4.1.11]
2997	GYS1; glycogen synthase 1 (muscle) [KO:K00693] [EC:2.4.1.11]
278	AMY1C; amylase, alpha 1C (salivary) [KO:K01176] [EC:3.2.1.1]
279	AMY2A; amylase, alpha 2A (pancreatic) [KO:K01176] [EC:3.2.1.1]
276	AMY1A; amylase, alpha 1A (salivary) [KO:K01176] [EC:3.2.1.1]
280	AMY2B; amylase, alpha 2B (pancreatic) [KO:K01176] [EC:3.2.1.1]
277	AMY1B; amylase, alpha 1B (salivary) [KO:K01176] [EC:3.2.1.1]
178	AGL; amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase [KO:K01196] [EC:3.2.1.33 2.4.1.25]
5167	ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1 [KO:K01513] [EC:3.6.1.9 3.1.4.1]
5169	ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase 3 [KO:K01513] [EC:3.6.1.9 3.1.4.1]

Compound

C00029	UDP-glucose
C00031	D-Glucose
C00089	Sucrose
C00092	D-Glucose 6-phosphate
C00095	D-Fructose
C00103	D-Glucose 1-phosphate
C00167	UDP-glucuronate
C00181	D-Xylose
C00185	Cellobiose
C00190	UDP-D-xylose
C00191	D-Glucuronate
C00208	Maltose
C00221	beta-D-Glucose
C00252	Isomaltose
C00267	alpha-D-Glucose
C00333	D-Galacturonate
C00369	Starch
C00394	GDP-glucose
C00470	Pectate
C00498	ADP-glucose
C00501	CDP-glucose
C00617	UDP-D-galacturonate
C00663	beta-D-Glucose 1-phosphate
C00668	alpha-D-Glucose 6-phosphate
C00689	alpha,alpha'-Trehalose 6-phosphate
C00714	Pectin
C00718	Amylose
C00721	Dextrin
C00760	Cellulose
C00965	1,3-beta-D-Glucan
C00973	Cyclomaltodextrin
C01083	alpha,alpha-Trehalose
C01172	beta-D-Glucose 6-phosphate
C01231	alpha-D-Glucose 1,6-bisphosphate
C01798	D-Glucoside
C01935	Maltodextrin
C02013	Cellotetraose
C02336	beta-D-Fructose
C02352	1,4-beta-D-Xylan
C02591	Sucrose 6'-phosphate
C02995	Maltose 6'-phosphate
C03033	beta-D-Glucuronoside
C05345	beta-D-Fructose 6-phosphate
C05731	3-Ketosucrose
C06215	Levan
C06216	Celloheptaose
C06217	Cellohexaose
C06218	Cellopentaose
C06219	Cellotriose
C16688	Sucrose 6-phosphate
C20237	alpha-Maltose 1-phosphate

KO pathway

ko00500

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   BioSystems (1)   
Disease (4)   
   KEGG DISEASE (4)   
Drug (4)   
   KEGG DRUG (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (56)   
   KEGG GENES (56)   
All databases (67)   

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