KEGG   PATHWAY: hsa04020Help
Entry
hsa04020                    Pathway                                

Name
Calcium signaling pathway - Homo sapiens (human)
Description
Ca2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this external source of signal Ca2+ by activating various entry channels with widely different properties. The voltage-operated channels (VOCs) are found in excitable cells and generate the rapid Ca2+ fluxes that control fast cellular processes. There are many other Ca2+-entry channels, such as the receptor-operated channels (ROCs), for example the NMDA (N-methyl-D-aspartate) receptors (NMDARs) that respond to glutamate. There also are second-messenger-operated channels (SMOCs) and store-operated channels (SOCs).
The other principal source of Ca2+ for signalling is the internal stores that are located primarily in the endoplasmic/sarcoplasmic reticulum (ER/SR), in which inositol-1,4,5-trisphosphate receptors (IP3Rs) or ryanodine receptors (RYRs) regulate the release of Ca2+. The principal activator of these channels is Ca2+ itself and this process of Ca2+-induced Ca2+ release is central to the mechanism of Ca2+ signalling. Various second messengers or modulators also control the release of Ca2+. IP3, which is generated by pathways using different isoforms of phospholipase C (PLCbeta, delta, epsilon, gamma and zeta), regulates the IP3Rs. Cyclic ADP-ribose (cADPR) releases Ca2+ via RYRs. Nicotinic acid adenine dinucleotide phosphate (NAADP) may activate a distinct Ca2+ release mechanism on separate acidic Ca2+ stores. Ca2+ release via the NAADP-sensitive mechanism may also feedback onto either RYRs or IP3Rs. cADPR and NAADP are generated by CD38. This enzyme might be sensitive to the cellular metabolism, as ATP and NADH inhibit it.
The influx of Ca2+ from the environment or release from internal stores causes a very rapid and dramatic increase in cytoplasmic calcium concentration, which has been widely exploited for signal transduction. Some proteins, such as troponin C (TnC) involved in muscle contraction, directly bind to and sense Ca2+. However, in other cases Ca2+ is sensed through intermediate calcium sensors such as calmodulin (CALM).
Class
Environmental Information Processing; Signal transduction
BRITE hierarchy
Pathway map
Calcium signaling pathway
hsa04020

All organismsOrtholog table
Disease
H00441  
Progressive osseous heteroplasia (POH)
H00608  
46,XY disorders of sex development (Disorders in androgen synthesis or action)
H00627  
Premature ovarian failure
H00699  
Central core disease
H00715  
Darier disease
H00728  
Brugada syndrome (BRS)
H00746  
Hypokalemic periodic paralysis (HypoPP)
H00749  
Episodic ataxias
H00755  
Acrokeratosis verruciformis
H00759  
Waardenburg syndrome (WS)
H00775  
Familial or sporadic hemiplegic migraine
H00787  
Congenital stationary night blindness (CSNB)
H00801  
Familial thoracic aortic aneurysm and dissection (TAAD)
H00823  
ABCD syndrome
H00865  
Lethal congenital contractural syndrome (LCCS)
H00910  
Hirschsprung disease (HD)
H00937  
Precocious puberty
H01019  
Catecholaminergic polymorphic ventricular tachycardia
H01118  
Progressive external ophthalmoplegia (PEO)
H01129  
Brody myopathy
H01307  
Nonsyndromic congenital nail disorder (NDNC)
H01310  
Multi-minicore disease (MmD)
Drug
D00045  
Adenosine (JAN/USP)
D00059  
Levodopa (JP16/USP/INN)
D00076  
Noradrenaline (JP16)
D00081  
Dinoprost (JP16/USAN/INN)
D00089  
Oxytocin (JP16/USP/INN)
D00095  
Adrenaline (JP16)
D00101  
Vasopressin (JP16/USP)
D00113  
Atropine (USP)
D00124  
Ephedrine (USP)
D00138  
Scopolamine (INN)
D00147  
Hyoscyamine (USP)
D00150  
Angiotensin II (INN)
D00176  
Protirelin (JP16/USAN/INN)
D00180  
Alprostadil (JP16/USP/INN)
D00227  
Aminophylline (USP/INN)
D00232  
Methyloctatropine bromide (JAN)
D00234  
Astemizole (JAN/USP/INN)
D00235  
Atenolol (JP16/USP/INN)
D00255  
Carvedilol (JAN/USAN/INN)
D00270  
Chlorpromazine (USP/INN)
D00274  
Cisapride (USAN/INN)
D00283  
Clozapine (JAN/USP/INN)
D00291  
Desmopressin (INN)
D00295  
Cimetidine (JP16/USP/INN)
D00300  
Diphenhydramine (JP16/INN)
D00304  
Divalproex sodium (USP)
D00318  
Famotidine (JP16/USP/INN)
D00319  
Felodipine (JAN/USP/INN)
D00349  
Isradipine (USP/INN)
D00356  
Latanoprost (JAN/USAN/INN)
D00357  
Losartan potassium (JP16/USAN)
D00364  
Loratadine (JAN/USAN/INN)
D00366  
Lypressin (USP/INN)
D00371  
Theophylline (JP16)
D00374  
Tiotixene (JAN)
D00378  
Timolol (USAN)
D00397  
Tropicamide (JP16/USP/INN)
D00399  
Valproic acid (USP)
D00400  
Valsartan (JP16/USAN/INN)
D00403  
Levomepromazine (USAN/INN)
D00411  
Zafirlukast (JAN/USAN/INN)
D00422  
Ranitidine (USAN/INN)
D00426  
Risperidone (JP16/USAN/INN)
D00432  
Nadolol (JP16/USP/INN)
D00437  
Nifedipine (JP16/USP/INN)
D00438  
Nimodipine (USAN/INN)
D00440  
Nizatidine (JP16/USP/INN)
D00454  
Olanzapine (JAN/USAN/INN)
D00458  
Quetiapine fumarate (JP16/USAN)
D00465  
Oxybutynin (USAN/INN)
D00480  
Promethazine hydrochloride (JP16/USP)
D00481  
Propantheline bromide (JP16/USP/INN)
D00483  
Propranolol hydrochloride (JP16/USP)
D00485  
Pseudoephedrine hydrochloride (USP)
D00494  
Promethazine (JAN/INN)
D00502  
Pergolide mesilate (JAN)
D00507  
Phenoxybenzamine hydrochloride (USP)
D00509  
Phentolamine mesilate (JAN/INN)
D00511  
Phenylephrine hydrochloride (JP16/USP)
D00513  
Pindolol (JP16/USP/INN)
D00520  
Dimenhydrinate (JP16/USP/INN)
D00521  
Terfenadine (JAN/USAN/INN)
D00522  
Candesartan (USAN/INN)
D00523  
Irbesartan (JAN/USAN/INN)
D00524  
Carbachol (JAN/USP/INN)
D00525  
Pilocarpine (JAN/USP)
D00528  
Anhydrous caffeine (JP16)
D00529  
Montelukast sodium (JAN/USAN)
D00537  
Topiramate (JAN/USAN/INN)
D00538  
Zonisamide (JAN/USAN/INN)
D00539  
Ethosuximide (JP16/USP/INN)
D00540  
Glycopyrronium bromide (JAN/INN)
D00560  
Pimozide (JP16/USP/INN)
D00561  
Sertindole (USAN/INN)
D00563  
Mirtazapine (JAN/USAN/INN)
D00597  
Acebutolol hydrochloride (JP16/USP)
D00598  
Betaxolol hydrochloride (JP16/USP)
D00599  
Carteolol hydrochloride (JP16/USP)
D00600  
Labetalol hydrochloride (JP16/USP)
D00601  
Metoprolol tartrate (JP16/USP)
D00602  
Penbutolol sulfate (JP16/USP)
D00603  
Timolol maleate (JP16/USP)
D00607  
Guanadrel sulfate (USP)
D00608  
Doxazosin mesilate (JP16)
D00609  
Prazosin hydrochloride (JP16/USP)
D00610  
Terazosin hydrochloride hydrate (JAN)
D00611  
Mecamylamine hydrochloride (USP)
D00613  
Fenoldopam mesylate (USP)
D00615  
Amlodipine besilate (JP16)
D00616  
Diltiazem hydrochloride (JP16/USP)
D00617  
Nicardipine hydrochloride (JP16/USAN)
D00618  
Nisoldipine (JAN/USAN/INN)
D00619  
Verapamil hydrochloride (JP16/USP)
D00626  
Candesartan cilexetil (JP16/USAN)
D00627  
Telmisartan (JAN/USAN/INN)
D00629  
Nitrendipine (JP16/USAN/INN)
D00631  
Bepridil hydrochloride hydrate (JAN)
D00632  
Dobutamine hydrochloride (JP16/USP)
D00633  
Dopamine hydrochloride (JP16/USP)
D00634  
Bisoprolol fumarate (JP16/USP)
D00635  
Metoprolol succinate (USP)
D00636  
Amiodarone hydrochloride (JP16/USAN)
D00644  
Esmolol hydrochloride (JAN/USAN)
D00646  
Tolterodine (USAN/INN)
D00659  
Azelastine hydrochloride (JP16/USAN)
D00661  
Cevimeline hydrochloride hydrate (JAN)
D00662  
Azatadine maleate (USP)
D00663  
Brompheniramine maleate (USAN)
D00664  
Cetirizine hydrochloride (JP16/USAN)
D00665  
Chlorpheniramine maleate (JP16/USP)
D00666  
Clemastine fumarate (JP16/USP)
D00668  
d-Chlorpheniramine maleate (JP16)
D00669  
Diphenhydramine hydrochloride (JP16/USP)
D00671  
Fexofenadine hydrochloride (JP16/USAN)
D00672  
Hydroxyzine hydrochloride (JP16/USP)
D00673  
Ranitidine hydrochloride (JP16/USP)
D00679  
Ergotamine tartrate (JP16/USP)
D00680  
Methylergometrine maleate (JP16)
D00682  
Carboprost tromethamine (USP)
D00683  
Salbutamol sulfate (JP16)
D00684  
Bitolterol mesilate (JAN)
D00685  
Orciprenaline sulfate (JP16)
D00686  
Pirbuterol acetate (USAN)
D00687  
Salmeterol xinafoate (JAN/USAN)
D00688  
Terbutaline sulfate (JP16/USP)
D00710  
Sodium valproate (JP16)
D00711  
Ketamine hydrochloride (JP16/USP)
D00715  
Hyoscine methobromide (INN)
D00717  
Dicyclomine hydrochloride (JAN/USP)
D00719  
Hyoscyamine sulfate (USP)
D00720  
Mepenzolate bromide (JP16/INN)
D00721  
Methanthelinium bromide (INN)
D00722  
Oxybutynin hydrochloride (JAN)
D00723  
Tridihexethyl chloride (BAN)
D00726  
Metoclopramide (JP16/INN)
D00740  
Procaine hydrochloride (JP16/USP)
D00743  
Naphazoline hydrochloride (JP16/USP)
D00756  
Tetrahydrozoline nitrate (JAN)
D00757  
Xylometazoline hydrochloride (USP)
D00774  
Orphenadrine citrate (USP)
D00777  
Amantadine hydrochloride (JP16/USP)
D00778  
Benztropine mesilate (JAN)
D00779  
Biperiden (JAN/USP/INN)
D00782  
Procyclidine hydrochloride (USP)
D00787  
Trihexyphenidyl hydrochloride (JP16/USP)
D00789  
Chlorpromazine hydrochloride (JP16/USP)
D00819  
Nefazodone hydrochloride (USAN)
D00820  
Trazodone hydrochloride (JAN/USP)
D00848  
Dextromethorphan hydrobromide hydrate (JP16)
D00996  
Epinephrine hydrochloride (JAN)
D00997  
Tolazoline hydrochloride (JAN/USP)
D00999  
Acetylcholine chloride (JP16/USP/INN)
D01000  
Bethanechol chloride (JP16/USP)
D01002  
Cyclopentolate hydrochloride (JP16/USP)
D01003  
Hexocyclium metilsulfate (INN)
D01004  
Homatropine hydrobromide (JP16/USP)
D01005  
Isopropamide iodide (JAN/USP/INN)
D01006  
Oxyphencyclimine hydrochloride (JAN)
D01007  
Propiverine hydrochloride (JP16)
D01017  
Dipivefrin hydrochloride (JAN/USP)
D01019  
Metaraminol bitartrate (JAN/USP)
D01020  
Methoxamine hydrochloride (JAN)
D01021  
Naphazoline nitrate (JP16)
D01022  
Oxymetazoline hydrochloride (JAN/USP)
D01023  
Tetrahydrozoline hydrochloride (JAN/USP)
D01024  
Tamsulosin hydrochloride (JP16/USAN)
D01025  
Levobunolol hydrochloride (JAN/USP)
D01026  
Sotalol hydrochloride (JAN/USP)
D01044  
Flupentixol (INN)
D01051  
Spiperone (JAN/USAN)
D01077  
Atropine methonitrate (JAN/INN)
D01096  
Hydroxyzine pamoate (JP16/USP)
D01103  
Trospium chloride (JAN/USAN/INN)
D01104  
Barnidipine hydrochloride (JAN)
D01117  
Mizolastine (JAN/INN)
D01118  
Profenamine hydrochloride (JAN)
D01123  
Seratrodast (JAN/USAN/INN)
D01128  
Ramatroban (JAN/INN)
D01131  
Lafutidine (JP16/INN)
D01143  
Isothipendyl hydrochloride (JAN)
D01145  
Azelnidipine (JP16/INN)
D01148  
Tolterodine tartrate (JAN/USAN)
D01163  
Ergometrine maleate (JP16)
D01164  
Aripiprazole (JAN/USAN/INN)
D01165  
Piperidolate hydrochloride (JAN)
D01172  
Diphenylpyraline hydrochloride (JAN)
D01173  
Cilnidipine (JAN/INN)
D01174  
Pheniramine maleate (JAN/USP)
D01175  
Carpronium chloride (JAN/INN)
D01176  
Blonanserin (JAN/INN)
D01182  
Alprenolol hydrochloride (JP16/USAN)
D01192  
Olopatadine hydrochloride (JAN/USAN)
D01193  
Osutidine (JAN/INN)
D01201  
Tiemonium iodide (JAN/INN)
D01204  
Olmesartan medoxomil (JAN/USAN)
D01227  
Bosentan hydrate (JAN)
D01231  
Piroheptine hydrochloride (JAN)
D01236  
Conivaptan hydrochloride (JAN/USAN)
D01242  
Promethazine teoclate (JAN/INN)
D01263  
Ritodrine hydrochloride (JP16/USP)
D01269  
Solifenacin succinate (JAN/USAN/INN)
D01290  
Nicergoline (JP16/USAN/INN)
D01295  
Cinnarizine (JAN/USAN/INN)
D01297  
Pirenzepine hydrochloride (USAN)
D01303  
Flunarizine hydrochloride (JAN/USAN)
D01307  
Midodrine hydrochloride (JAN/USAN)
D01315  
Methylbenactyzium bromide (JP16/INN)
D01317  
Meclizine hydrochloride (JAN/USP)
D01321  
Zotepine (JAN/INN)
D01324  
Mequitazine (JP16/INN)
D01332  
Ketotifen fumarate (JP16/USAN)
D01333  
Urapidil (JP16/INN)
D01336  
Carbinoxamine maleate (JAN/USP)
D01343  
Dimetindene maleate (JAN)
D01347  
Tramazoline hydrochloride (JAN/USAN)
D01349  
Pirbuterol hydrochloride (JAN/USAN)
D01352  
Dinoprost tromethamine (JAN/USP)
D01358  
Mianserin hydrochloride (JAN/USAN)
D01359  
Etomidoline (JAN/INN)
D01360  
Clenbuterol hydrochloride (JAN/USP)
D01362  
Tulobuterol hydrochloride (JP16)
D01369  
Bevantolol hydrochloride (JAN/USAN)
D01373  
Formoterol fumarate (USAN)
D01377  
Prifinium bromide (JAN/INN)
D01386  
Ephedrine hydrochloride (JP16/USP)
D01390  
dl-Isoprenaline hydrochloride (JAN)
D01405  
Norfenefrine hydrochloride (JAN)
D01428  
Fenoterol hydrobromide (JAN)
D01441  
Imatinib mesilate (JAN)
D01444  
Bunitrolol hydrochloride (JAN)
D01445  
Ifenprodil tartrate (JP16)
D01451  
Scopolamine butylbromide (JP16)
D01452  
Isopropyl unoprostone (JAN)
D01453  
Caffeine hydrate (JP16)
D01454  
Bupranolol hydrochloride (JP16)
D01460  
Homochlorcyclizine hydrochloride (JP16)
D01463  
Diponium bromide (JAN/INN)
D01467  
Roxatidine acetate hydrochloride (JP16/USAN)
D01469  
Amosulalol hydrochloride (JP16)
D01471  
Esatenolol (JAN/INN)
D01477  
Opipramol hydrochloride (JAN/USAN)
D01478  
Ebastine (JP16/USAN/INN)
D01482  
Pipamperone hydrochloride (JAN)
D01491  
Butropium bromide (JP16/INN)
D01500  
Trimebutine maleate (JP16)
D01504  
Bufetolol hydrochloride (JP16)
D01512  
Befunolol hydrochloride (JAN)
D01520  
Levomepromazine hydrochloride (JAN/USAN)
D01521  
Pipethanate hydrochloride (JAN)
D01538  
Valethamate bromide (JAN)
D01543  
Nylidrin hydrochloride (JAN)
D01548  
Mosapramine hydrochloride (JAN)
D01553  
Manidipine hydrochloride (JP16)
D01562  
Aranidipine (JAN/INN)
D01571  
Moxisylyte hydrochloride (JAN)
D01573  
Etilefrine hydrochloride (JP16)
D01589  
Mabuterol hydrochloride (JAN)
D01592  
Betahistine mesilate (JP16)
D01600  
Diphenylpiperidinomethyldioxolan iodide (JAN)
D01604  
Efonidipine hydrochloride ethanolate (JAN)
D01624  
Sarpogrelate hydrochloride (JP16)
D01627  
Diphenylpyraline teoclate (JAN)
D01635  
Methoxyphenamine hydrochloride (JAN)
D01648  
Hyoscyamine methylbromide (JAN)
D01652  
Apafant (JAN/USAN/INN)
D01654  
Bepotastine besilate (JAN)
D01674  
Naftopidil (JAN/INN)
D01691  
Nipradilol (JAN/INN)
D01692  
Alfuzosin hydrochloride (JAN/USAN)
D01697  
Colforsin daropate hydrochloride (JAN)
D01698  
Dalcotidine (JAN/INN)
D01699  
Darifenacin hydrobromide (JAN/USAN)
D01712  
Theophylline sodium acetate (JAN)
D01713  
Epinastine hydrochloride (JAN)
D01717  
Levocabastine hydrochloride (JAN/USAN)
D01741  
Celiprolol hydrochloride (JAN/USAN)
D01742  
Clebopride malate (JP16)
D01748  
Isoxsuprine hydrochloride (JP16/USP)
D01771  
Proxyphylline (JAN/INN)
D01773  
Oxatomide (JAN/USAN/INN)
D01782  
Triprolidine hydrochloride hydrate (JAN)
D01794  
Bopindolol malonate (JAN)
D01795  
Tilisolol hydrochloride (JAN)
D01801  
Thonzylamine hydrochloride (JAN/USAN)
D01806  
Oxprenolol hydrochloride (JP16/USP)
D01815  
Oxapium iodide (JP16/INN)
D01818  
Proglumide (JP16/USAN/INN)
D01830  
Arotinolol hydrochloride (JP16)
D01835  
Clorprenaline hydrochloride (JAN/USAN)
D01847  
Landiolol hydrochloride (JAN)
D01849  
Lercanidipine hydrochloride (JAN/USAN)
D01858  
Panazepide (JAN)
D01861  
Pibutidine hydrochloride (JAN)
D01869  
Ornoprostil (JAN/INN)
D01871  
Metixene hydrochloride (JAN)
D01875  
Tiquizium bromide (JAN/INN)
D01887  
Bunazosin hydrochloride (JP16)
D01902  
Dimetotiazine mesilate (JAN)
D01908  
Nilvadipine (JP16/USAN/INN)
D01922  
Pratosartan (JAN/INN)
D01925  
Taltirelin hydrate (JP16)
D01929  
Tiotropium bromide hydrate (JAN)
D01939  
Ziprasidone hydrochloride hydrate (JAN)
D01946  
Oxitropium bromide (JAN/INN)
D01952  
L-Methylephedrine hydrochloride (JAN)
D01955  
Aclatonium napadisilate (JAN)
D01958  
Indenolol hydrochloride (JP16)
D01964  
Travoprost (JAN/USAN/INN)
D01965  
Silodosin (JAN/INN)
D01969  
Gallopamil hydrochloride (JAN)
D01976  
N-Methylscopolamine methylsulfate (JAN)
D01977  
Gefitinib (JAN/USAN/INN)
D01978  
Trimetoquinol hydrochloride
D01987  
Pipethanate ethobromide (JAN)
D01994  
Mosapride citrate hydrate (JP16)
D02004  
Apomorphine hydrochloride hydrate (JAN)
D02007  
Protirelin tartrate hydrate (JP16)
D02014  
Angiotensin II (human type) (JAN)
D02017  
Choline theophylline (JAN)
D02034  
Setiptiline maleate (JAN)
D02045  
Benidipine hydrochloride (JP16)
D02066  
Isoprenaline sulfate (JAN)
D02069  
Atropine sulfate (JP16/USP)
D02070  
Homatropine methylbromide (USP)
D02071  
Scopolamine hydrobromide hydrate (JP16)
D02073  
Gemeprost (JAN/USAN/INN)
D02081  
Metipranolol hydrochloride
D02082  
Eprosartan mesylate (USAN)
D02090  
Cyclizine lactate (BAN)
D02091  
Tripelennamine hydrochloride (USP)
D02092  
Cisapride (JAN)
D02093  
Isoetharine hydrochloride (USP)
D02100  
Ziprasidone mesylate (USAN)
D02102  
Methadone hydrochloride (JAN/USP)
D02109  
dl-Methylephedrine hydrochloride (JP16)
D02147  
Albuterol (USP)
D02148  
Phenindamine tartrate (USAN)
D02149  
Epinephrine bitartrate (JAN/USP)
D02150  
l-Isoprenaline hydrochloride (JP16)
D02151  
Tulobuterol (JAN/INN)
D02200  
Pilocarpine hydrochloride (JP16/USP)
D02202  
Lobeline hydrochloride (JAN)
D02204  
Hexamethonium bromide (JAN/INN)
D02211  
Dihydroergotamine mesilate (JP16)
D02212  
Ipratropium bromide hydrate (JP16)
D02213  
Metoclopramide hydrochloride (JAN)
D02234  
Cyproheptadine hydrochloride (JP16/USP)
D02235  
Desmopressin acetate hydrate (JAN)
D02236  
Flupentixol dihydrochloride (JAN)
D02245  
Alimemazine tartrate (JP16)
D02246  
Biperiden hydrochloride (JP16/USP)
D02247  
Biperiden lactate (JAN/USP)
D02248  
Levomepromazine maleate (JP16/USAN)
D02249  
Emedastine difumarate (JP16/USP)
D02274  
Dantrolene sodium hydrate (JP16)
D02281  
Levalbuterol hydrochloride (USAN)
D02327  
Doxylamine succinate (USP)
D02338  
Acebutolol (USAN/INN)
D02342  
Bisoprolol (JAN/USAN/INN)
D02343  
Carboprost (USAN/INN)
D02347  
Dantrolene (USAN/INN)
D02349  
Dipivefrin (USAN)
D02356  
Verapamil (USAN/INN)
D02358  
Metoprolol (USAN/INN)
D02359  
Ritodrine (USAN/INN)
D02363  
Ketanserin (USAN/INN)
D02364  
Lobeline (INN)
D02372  
Perospirone hydrochloride hydrate (JAN)
D02374  
Metipranolol (USAN/INN)
D02384  
Verlukast (USAN/INN)
D02389  
Primidolol (USAN/INN)
D02396  
Hexoprenaline sulfate (USAN)
D02404  
Procaterol hydrochloride (USAN)
D02410  
Selfotel (USAN/INN)
D02417  
Flutropium bromide (JAN)
D02419  
Diphenhydramine salicylate (JAN)
D02535  
Timepidium bromide hydrate (JP16)
D02537  
Dronedarone (INN)
D02577  
Flibanserin (USAN/INN)
D02578  
Agomelatine (INN)
D02588  
Montirelin (INN)
D02590  
Israpafant (JAN/INN)
D02599  
Orphenadrine hydrochloride
D02612  
Thiothixene hydrochloride (USP)
D02613  
Clopenthixol (USAN)
D02614  
Denopamine (JAN/INN)
D02622  
Pipamperone (USAN/INN)
D02630  
Penfluridol (USAN/INN)
D02641  
Butaclamol hydrochloride (USAN)
D02656  
Fananserin (USAN/INN)
D02666  
Iloperidone (USAN/INN)
D02676  
Oxiperomide (USAN/INN)
D02692  
Human menopausal gonadotrophin (JP16)
D02693  
Devazepide (USAN/INN)
D02702  
Talibegron hydrochloride (USAN)
D02705  
Alprostadil alfadex (JP16)
D02710  
Tarazepide (INN)
D02719  
Rosaprostol (INN)
D02722  
Limaprost (INN)
D02724  
Bimatoprost (JAN/USAN/INN)
D02730  
Tegaserod maleate (USAN)
D02732  
Pranlukast hydrate (JAN)
D02739  
Ablukast (USAN/INN)
D02741  
Ablukast sodium (USAN)
D02750  
Aceclidine (USAN/INN)
D02760  
Acrivastine (USAN/INN)
D02765  
Adaprolol maleate (USAN)
D02767  
Adatanserin hydrochloride (USAN)
D02775  
Adrogolide hydrochloride (USAN)
D02780  
Acamprosate calcium (JAN/USAN)
D02834  
Alprenoxime hydrochloride (USAN)
D02836  
Altanserin tartrate (USAN)
D02846  
Cinalukast (USAN/INN)
D02848  
Pobilukast edamine (USAN)
D02849  
Ritolukast (USAN/INN)
D02850  
Sulukast (USAN/INN)
D02851  
Tomelukast (USAN/INN)
D02860  
Limaprost alfadex (JP16)
D02876  
Alvameline maleate (USAN)
D02893  
Amesergide (USAN/INN)
D02901  
Amidephrine mesylate (USAN)
D02910  
Amiodarone (USAN/INN)
D02914  
Amlodipine maleate (USAN)
D02939  
Angiotensin amide (USAN)
D02950  
Antazoline phosphate (USP)
D02968  
Aprepitant (JAN/USAN/INN)
D02973  
Aptiganel hydrochloride (USAN)
D02976  
Arbutamine hydrochloride (USAN)
D02981  
Arformoterol tartrate (USAN)
D02983  
Argipressin tannate (USAN)
D02995  
Asenapine maleate (USAN)
D03008  
Atosiban (USAN/INN)
D03009  
Atrasentan hydrochloride (USAN)
D03011  
Atropine oxide hydrochloride (USAN)
D03065  
Becaplermin (USAN/INN)
D03087  
Benzetimide hydrochloride (USAN)
D03102  
Betahistine hydrochloride (USP)
D03120  
Binodenoson (USAN/INN)
D03166  
Bromodiphenhydramine hydrochloride (USP)
D03170  
Bucindolol hydrochloride (USAN)
D03177  
Bunolol hydrochloride (USAN)
D03195  
Butopamine (USAN/INN)
D03198  
Butoxamine hydrochloride (USAN)
D03212  
Apadenoson (USAN)
D03218  
Axitinib (JAN/USAN)
D03221  
Befetupitant (USAN/INN)
D03264  
Mazaticol hydrochloride hydrate (JAN)
D03274  
Chlorpromazine hibenzate (JAN)
D03276  
Profenamine hibenzate (JAN)
D03285  
Diphenhydramine tannate (JP16)
D03290  
Promethazine methylenedisalicylate (JAN)
D03334  
Gonadotrophin, chorionic (JAN)
D03350  
Canertinib dihydrochloride (USAN)
D03360  
Diphenhydramine laurylsulfate (JAN)
D03399  
Carboprost methyl (USAN)
D03402  
Carbuterol hydrochloride (USAN)
D03415  
Carvedilol phosphate hydrate (JAN)
D03449  
Cetamolol hydrochloride (USAN)
D03455  
Cetuximab (genetical recombination) (JAN)
D03475  
Chlorpheniramine polistirex (USAN)
D03478  
Choriogonadotropin alfa (USAN/INN)
D03490  
Cicloprolol hydrochloride (USAN)
D03494  
Ciladopa hydrochloride (USAN)
D03502  
Cimaterol (USAN/INN)
D03503  
Cimetidine hydrochloride (USP)
D03506  
Cinanserin hydrochloride (USAN)
D03534  
Clebopride (USAN)
D03535  
Clemastine (USAN)
D03556  
Zuclopenthixol (INN)
D03587  
Colterol mesylate (USAN)
D03621  
Cyclizine (INN)
D03622  
Cyclizine hydrochloride (USP)
D03642  
Daltroban (USAN/INN)
D03648  
Dapiprazole hydrochloride (USAN)
D03654  
Darifenacin (USAN/INN)
D03655  
Darodipine (USAN/INN)
D03658  
Dasatinib (INN)
D03677  
Deltibant (USAN/INN)
D03679  
Delucemine hydrochloride (USAN)
D03693  
Desloratadine (USAN/INN)
D03704  
Dexbrompheniramine maleate (USAN)
D03711  
Dexetimide (USAN/INN)
D03729  
Dexpropranolol hydrochloride (USAN)
D03742  
Dextromethorphan (USP)
D03744  
Dextromethorphan polistirex (USAN)
D03746  
Dextrorphan hydrochloride (USAN)
D03759  
Diacetolol hydrochloride (USAN)
D03814  
Atropine methylbromide (JAN)
D03830  
Diltiazem malate (USAN)
D03854  
Diphenhydramine citrate (USP)
D03878  
Dizocilpine maleate (USAN)
D03879  
Dobutamine (USP/INN)
D03880  
Dobutamine lactobionate (USAN)
D03881  
Dobutamine tartrate (USP)
D03889  
Donetidine (USAN)
D03891  
Dopexamine (USAN/INN)
D03914  
Dronedarone hydrochloride (USAN)
D03937  
Ecopipam hydrochloride (USAN)
D03953  
Edonentan (USAN)
D04018  
Ephedrine sulfate (USP)
D04023  
Erlotinib hydrochloride (JAN/USAN)
D04024  
Lapatinib tosilate hydrate (JAN)
D04025  
Mubritinib (USAN/INN)
D04034  
Chlorpromazine phenolphthalinate (JAN)
D04040  
Eprosartan (USAN/INN)
D04057  
Esoxybutynin chloride (USAN)
D04074  
Etalocib (USAN)
D04087  
Ethybenztropine (USAN)
D04098  
Etintidine hydrochloride (USAN)
D04116  
Eucatropine hydrochloride (USP XXXII)
D04126  
Saralasin acetate (USAN)
D04137  
Felypressin (USAN/INN)
D04155  
Fenobam (USAN)
D04157  
Fenoterol (USAN/INN)
D04184  
Fiduxosin hydrochloride (USAN)
D04190  
Flestolol sulfate (USAN)
D04226  
Flupirtine maleate (USAN)
D04243  
Forasartan (USAN/INN)
D04308  
Gavestinel (USAN/INN)
D04320  
Glemanserin (USAN/INN)
D04479  
Hyoscyamine hydrobromide (USP)
D04488  
Ibopamine (USAN/INN)
D04492  
Icatibant acetate (USAN)
D04494  
Icotidine (USAN)
D04500  
Ifetroban (USAN/INN)
D04501  
Ifetroban sodium (USAN)
D04517  
Impromidine hydrochloride (USAN)
D04531  
Indoramin (USAN/INN)
D04532  
Indoramin hydrochloride (USAN)
D04625  
Isoetharine (USP)
D04626  
Isoetharine mesylate (USP)
D04641  
Istradefylline (JAN/USAN/INN)
D04657  
Lacidipine (USAN/INN)
D04680  
Lavoltidine succinate (USAN)
D04701  
Levalbuterol sulfate (USAN)
D04703  
Levalbuterol tartrate (USAN)
D04708  
Levdobutamine lactobionate (USAN)
D04710  
Levobetaxolol hydrochloride (USAN)
D04724  
Lexipafant (USAN/INN)
D04728  
Licostinel (USAN/INN)
D04788  
Lubazodone hydrochloride (USAN)
D04794  
Lupitidine hydrochloride (USAN)
D04820  
Lurasidone hydrochloride (JAN/USAN)
D04824  
Lutropin alfa (USAN/INN)
D04860  
Maropitant citrate (USAN)
D04888  
Medroxalol (USAN/INN)
D04889  
Medroxalol hydrochloride (USAN)
D04905  
Memantine hydrochloride (JAN/USAN)
D04954  
Metaproterenol polistirex (USAN)
D04970  
Methacholine chloride (USAN/INN)
D05004  
Metiamide (USAN/INN)
D05008  
Metoclopramide hydrochloride (USAN)
D05011  
Metoprolol fumarate (USP)
D05015  
Metrenperone (USAN/INN)
D05024  
Mibefradil dihydrochloride (USAN)
D05029  
Midostaurin (USAN/INN)
D05035  
Milameline hydrochloride (USAN)
D05037  
Trimetoquinol hydrochloride hydrate (JP16)
D05085  
Moxilubant maleate (USAN)
D05107  
Nafronyl oxalate (USAN)
D05127  
Nebivolol (USAN/INN)
D05145  
Neramexane mesylate (USAN)
D05196  
Noberastine (USAN/INN)
D05206  
Norepinephrine bitartrate (USP)
D05246  
Olmesartan (USAN/INN)
D05258  
Serum gonadotrophin (JP16)
D05276  
Pirenzepine hydrochloride hydrate (JP16)
D05277  
Formoterol fumarate hydrate (JP16)
D05306  
Oxmetidine hydrochloride (USAN)
D05307  
Oxmetidine mesylate (USAN)
D05339  
Paliperidone (JAN/USAN/INN)
D05340  
Paliperidone palmitate (JAN/USAN)
D05345  
Pamatolol sulfate (USAN)
D05350  
Panitumumab (genetical recombination) (JAN)
D05366  
Procaterol hydrochloride hydrate (JP16)
D05380  
Pazopanib hydrochloride (JAN/USAN)
D05395  
Pelanserin hydrochloride (USAN)
D05399  
Pelitinib (USAN/INN)
D05429  
Aminophylline hydrate (JP16)
D05442  
Perhexiline maleate (USAN)
D05446  
Pertuzumab (genetical recombination) (JAN)
D05447  
Perzinfotel (USAN/INN)
D05453  
Phencyclidine hydrochloride (USAN)
D05471  
Piboserod hydrochloride (USAN)
D05476  
Picumeterol fumarate (USAN)
D05478  
Pilocarpine nitrate (USP)
D05523  
Pizotyline (USAN)
D05587  
Practolol (USAN)
D05606  
Prenalterol hydrochloride (USAN)
D05648  
Pseudoephedrine polistirex (USAN)
D05649  
Pseudoephedrine sulfate (USP)
D05660  
Pyrilamine maleate (USP)
D05691  
Ractopamine hydrochloride (USAN)
D05699  
Ranitidine bismuth citrate (USAN)
D05711  
Regadenoson (USAN/INN)
D05714  
Remacemide hydrochloride (USAN)
D05718  
Reproterol hydrochloride (USAN)
D05727  
Ridogrel (USAN/INN)
D05730  
Rimiterol hydrobromide (USAN)
D05738  
Ritanserin (USAN/INN)
D05742  
Rocastine hydrochloride (USAN)
D05779  
Sabcomeline hydrochloride (USAN)
D05792  
Salmeterol (USAN/INN)
D05832  
Sibenadet hydrochloride (USAN)
D05879  
Solabegron hydrochloride (USAN)
D05902  
Soterenol hydrochloride (USAN)
D05939  
Sufotidine (USAN/INN)
D05941  
Sulamserod hydrochloride (USAN)
D05970  
Sulotroban (USAN/INN)
D05996  
Talnetant hydrochloride (USAN)
D06000  
Talsaclidine fumarate (USAN)
D06005  
Tandutinib (USAN/INN)
D06015  
Tazomeline citrate (USAN)
D06021  
Tecastemizole (USAN/INN)
D06056  
Tegaserod (USAN/INN)
D06063  
Temelastine (USAN/INN)
D06103  
Theophylline (USP)
D06104  
Theophylline sodium glycinate (USP)
D06120  
Thyrotropin alfa (genetical recombination) (JAN)
D06140  
Ticolubant (USAN/INN)
D06146  
Tiletamine hydrochloride (USP)
D06157  
Tiotidine (USAN/INN)
D06234  
Trimazosin hydrochloride (USAN)
D06246  
Tripelennamine citrate
D06253  
Tropanserin hydrochloride (USAN)
D06272  
Sorafenib tosilate (JAN)
D06273  
Imidafenacin (JAN/INN)
D06274  
Tafluprost (JAN/USAN/INN)
D06280  
Vapiprost hydrochloride (JAN/USAN)
D06285  
Vatalanib (USAN/INN)
D06293  
Vestipitant mesylate (USAN)
D06317  
Vofopitant dihydrochloride (USAN)
D06328  
Xamoterol (USAN)
D06329  
Xamoterol fumarate (USAN)
D06330  
Xanomeline (USAN)
D06331  
Xanomeline tartrate (USAN)
D06353  
Zacopride hydrochloride (USAN)
D06355  
Zaltidine hydrochloride (USAN)
D06374  
Zinterol hydrochloride (USAN)
D06394  
Dabuzalgron hydrochloride (USAN)
D06396  
Renzapride (INN)
D06402  
Sunitinib malate (JAN/USAN)
D06407  
Vandetanib (JAN/USAN/INN)
D06413  
Nilotinib hydrochloride hydrate (JAN)
D06414  
Dasatinib hydrate (JAN)
D06457  
Chorionic gonadotrophin (JP16)
D06459  
Purified human menopausal gonadotrophin (JAN)
D06477  
Serum gonadotrophin for injection (JP16)
D06552  
Alcaftadine (USAN/INN)
D06574  
Casopitant mesylate (USAN)
D06597  
Fosaprepitant meglumine (JAN)
D06613  
Lorcaserin hydrochloride (USAN)
D06622  
Nebivolol hydrochloride (USAN)
D06623  
Olanzapine pamoate (USAN)
D06632  
Pruvanserin (USAN/INN)
D06633  
Pruvanserin hydrochloride (USAN)
D06646  
Epanolol (USAN/INN)
D06659  
Tipelukast (USAN)
D06672  
Terlipressin (USAN/INN)
D06678  
Motesanib
D07058  
Acamprosate (INN)
D07072  
Niperotidine (INN)
D07076  
Camylofin (INN)
D07077  
Ambrisentan (JAN/INN)
D07099  
Cimetropium bromide (INN)
D07124  
Alfuzosin (INN)
D07125  
Alimemazine (INN)
D07140  
Picotamide (BAN)
D07148  
Oxedrine (BAN)
D07156  
Alprenolol (INN)
D07171  
Sitaxentan (USAN/INN)
D07181  
Mepindolol (INN)
D07182  
Tertatolol (INN)
D07183  
Cloranolol (INN)
D07184  
Talinolol (INN)
D07185  
Fendiline (INN)
D07197  
Bamipine (INN)
D07198  
Chlorphenoxamine (INN)
D07218  
Metergoline (INN)
D07226  
Fesoterodine (INN)
D07227  
Ornipressin (INN)
D07228  
Demoxytocin (INN)
D07229  
Carbetocin (INN/BAN)
D07283  
Esketamine (INN)
D07349  
Choline alfoscerate (INN)
D07377  
Bambuterol (INN)
D07398  
Chlorphenamine (INN)
D07402  
Levocetirizine (USAN/INN)
D07406  
Pimethixene (INN)
D07407  
Rupatadine (INN)
D07441  
Amantadine (INN)
D07450  
Amlodipine (INN)
D07451  
Amosulalol (INN)
D07458  
Antazoline (INN)
D07459  
Antazoline hydrochloride
D07460  
Apomorphine (BAN)
D07463  
Arformoterol (INN)
D07465  
Arotinolol (INN)
D07475  
Atosiban acetate
D07477  
Atropine oxide (INN)
D07482  
Azatadine (INN)
D07483  
Azelastine (INN)
D07489  
Bambuterol hydrochloride
D07492  
Bamipine dihydrochloride
D07493  
Bamipine lactate
D07494  
Barnidipine (INN)
D07509  
Benidipine (INN)
D07511  
Benzatropine (INN)
D07513  
Benzetimide (INN)
D07520  
Bepridil (INN)
D07522  
Betahistine (INN)
D07526  
Betaxolol (INN)
D07534  
Bitolterol (INN)
D07537  
Bopindolol (INN)
D07538  
Bosentan (INN)
D07543  
Brompheniramine (INN)
D07550  
Bunazosin (INN)
D07551  
Buphenine (INN)
D07590  
Bupranolol (INN)
D07603  
Caffeine citrate (USP)
D07608  
Carazolol (INN)
D07617  
Carbinoxamine (INN)
D07624  
Carteolol (INN)
D07660  
Celiprolol (INN)
D07662  
Cetirizine (INN)
D07667  
Cevimeline (INN)
D07682  
Clazosentan sodium (JAN)
D07684  
Chlorphenoxamine hydrochloride
D07713  
Clenbuterol (INN)
D07734  
Cinnarizine dihydrochloride
D07741  
Zibotentan (JAN/USAN/INN)
D07748  
Conivaptan (INN)
D07759  
Cyclopentolate (INN)
D07765  
Cyproheptadine (INN)
D07803  
Dexchlorpheniramine (INN)
D07804  
Dexetimide hydrochloride
D07820  
Dicycloverine (INN)
D07837  
Dihydroergotamine (INN)
D07838  
Dihydroergotamine tartrate
D07845  
Diltiazem (INN)
D07853  
Dimetindene (INN)
D07854  
Dimetotiazine (INN)
D07860  
Dioxopromethazine hydrochloride
D07862  
Diphenylpyraline (INN)
D07870  
Dopamine (INN)
D07874  
Doxazosin (INN)
D07878  
Doxylamine (INN)
D07886  
Efonidipine (INN)
D07890  
Emedastine (INN)
D07900  
Epinastine (INN)
D07905  
Ergometrine (INN)
D07906  
Ergotamine (INN)
D07907  
Erlotinib (INN)
D07916  
Esmolol (INN)
D07931  
Etilefrine (INN)
D07951  
Fentonium bromide (INN)
D07958  
Fexofenadine (INN)
D07971  
Flunarizine (INN)
D07976  
Flupentixol decanoate
D07978  
Flupirtine (INN)
D07979  
Flupirtine D-gluconate
D07990  
Formoterol (INN)
D08009  
Gallopamil (INN)
D08039  
Hexoprenaline (INN)
D08040  
Histamine (DCF)
D08041  
Homochlorcyclizine (INN)
D08054  
Hydroxyzine (INN)
D08057  
Ibopamine hydrochloride
D08064  
Ifenprodil (INN)
D08066  
Imatinib (INN)
D08067  
Azilsartan medoxomil (USAN)
D08074  
Penbutolol (INN)
D08078  
Indenolol (INN)
D08090  
Isoprenaline (INN)
D08091  
Isothipendyl (INN)
D08092  
Isoxsuprine (INN)
D08093  
Isoxsuprine lactate
D08098  
Ketamine (INN)
D08099  
Ketanserin tartrate
D08100  
Ketobemidone (INN)
D08101  
Ketobemidone hydrochloride
D08105  
Ketotifen (INN)
D08106  
Labetalol (INN)
D08108  
Lapatinib (INN)
D08111  
Lercanidipine (INN)
D08115  
Levobunolol (INN)
D08117  
Levocabastine (INN)
D08118  
Levocetirizine hydrochloride (JAN/USAN)
D08121  
Levomethadone (INN)
D08122  
Levomethadone hydrochloride
D08124  
Levosalbutamol (INN)
D08138  
Lobeline sulfate
D08146  
Losartan (INN)
D08155  
Manidipine (INN)
D08157  
Mazaticol (INN)
D08163  
Meclozine (BAN)
D08174  
Memantine (INN)
D08183  
Mepyramine (INN)
D08184  
Mepyramine theophyllineacetate
D08192  
Metaraminol (INN)
D08195  
Methadone (BAN)
D08201  
Methoxamine (BAN)
D08206  
Methylephedrine (BAN)
D08207  
Methylergometrine (INN)
D08209  
Metixene (INN)
D08212  
Trimazosin (INN)
D08216  
Mianserin (INN)
D08217  
Mibefradil (INN)
D08220  
Midodrine (INN)
D08229  
Montelukast (INN)
D08235  
Mosapramine (INN)
D08236  
Mosapride (INN)
D08239  
Moxisylyte (INN)
D08244  
Naftidrofuryl (INN)
D08253  
Naphazoline (INN)
D08257  
Nefazodone (INN)
D08270  
Nicardipine (INN)
D08271  
Nicergoline tartrate
D08284  
Norepinephrine hydrochoride
D08286  
Norfenefrine (INN)
D08293  
Olopatadine (INN)
D08297  
Opipramol (INN)
D08300  
Orciprenaline (INN)
D08305  
Orphenadrine (INN)
D08308  
Oxedrine tartrate
D08309  
Oxedrine hydrochloride
D08318  
Oxprenolol (INN)
D08322  
Oxymetazoline (INN)
D08325  
Oxyphencyclimine (INN)
D08339  
Pergolide (INN)
D08353  
Phenindamine (INN)
D08355  
Pheniramine (INN)
D08358  
Phenoxybenzamine (INN)
D08362  
Phentolamine (INN)
D08365  
Phenylephrine (INN)
D08366  
Phenylephrine tartrate
D08376  
Pilocarpine borate
D08382  
Piperidolate (INN)
D08384  
Pipethanate (INN)
D08387  
Pirbuterol (INN)
D08389  
Pirenzepine (INN)
D08395  
Piroheptine (INN)
D08397  
Pizotifen malate
D08408  
Pranlukast (INN)
D08411  
Prazosin (INN)
D08424  
Procaterol (INN)
D08425  
Procyclidine (INN)
D08426  
Profenamine (INN)
D08432  
Promethazine maleate
D08441  
Propiverine (INN)
D08443  
Propranolol (INN)
D08449  
Pseudoephedrine (INN)
D08456  
Quetiapine (INN)
D08474  
Reproterol (INN)
D08494  
Roxatidine (INN)
D08495  
Roxatidine acetate (BAN)
D08497  
Rupatadine fumarate
D08503  
Toceranib (USAN)
D08508  
Sarpogrelate (INN)
D08511  
Setiptiline (INN)
D08517  
Sitaxentan sodium (USAN)
D08522  
Solifenacin (INN)
D08524  
Sorafenib (USAN/INN)
D08525  
Sotalol (INN)
D08544  
Toceranib phosphate (USAN)
D08552  
Sunitinib (INN)
D08560  
Tamsulosin (INN)
D08569  
Terazosin (INN)
D08570  
Terbutaline (INN)
D08571  
Terlipressin acetate (JAN)
D08572  
Tertatolol hydrochloride
D08578  
Tetryzoline (INN)
D08587  
Thonzylamine (INN)
D08591  
Tiaprost (INN)
D08595  
Tiemonium methylsulfate
D08596  
Tiletamine (INN)
D08598  
Tilisolol (INN)
D08600  
Timolol (INN)
D08614  
Tolazoline (INN)
D08624  
Tramazoline (INN)
D08626  
Trazodone (INN)
D08629  
Tretoquinol (INN)
D08638  
Trihexyphenidyl (INN)
D08639  
Trimebutine (INN)
D08645  
Tripelennamine (INN)
D08648  
Triprolidine (INN)
D08660  
Ulobetasol (INN)
D08661  
Unoprostone (INN)
D08662  
Urapidil hydrochloride
D08667  
Calcium valproate
D08684  
Xylometazoline (INN)
D08687  
Ziprasidone (INN)
D08691  
Zuclopenthixol acetate
D08692  
Zuclopenthixol decanoate
D08693  
Zuclopenthixol dihydrochloride
D08768  
Promethazine hibenzate
D08837  
Aclidinium bromide (JAN/USAN/INN)
D08850  
Amibegron (USAN/INN)
D08851  
Amibegron hydrochloride (USAN)
D08864  
Azilsartan (JAN/USAN/INN)
D08865  
Azilsartan kamedoxomil (USAN)
D08892  
Clevidipine (USAN/INN)
D08923  
Fesoterodine fumarate (JAN/USP)
D08937  
Labradimil (INN/USAN)
D08945  
Milveterol hydrochloride (USAN)
D08947  
Motesanib phosphate (JAN)
D08950  
Neratinib (INN/USAN)
D08953  
Nilotinib (USAN/INN)
D08966  
Phenylephrine bitartrate (USP)
D08969  
Pimavanserin tartrate (USAN)
D08986  
Retosiban (USAN)
D08988  
Rolapitant hydrochloride (USAN)
D09003  
Sonedenoson (USAN)
D09205  
Prucalopride (USAN/INN)
D09318  
Indacaterol (USAN/INN)
D09319  
Indacaterol maleate (JAN/USAN)
D09344  
Fasobegron (INN)
D09378  
Serlopitant (USAN)
D09402  
Darotropium bromide (USAN/INN)
D09535  
Mirabegron (USAN/JAN)
D09570  
Bilastine (INN)
D09645  
Nelotanserin (USAN/INN)
D09650  
Orvepitant (USAN/INN)
D09651  
Orvepitant maleate (USAN)
D09689  
Varlitinib (USAN/INN)
D09690  
Varlitinib tosylate (USAN)
D09693  
Velusetrag (USAN/INN)
D09694  
Velusetrag hydrochloride (USAN)
D09696  
Vilanterol (USAN)
D09697  
Vilanterol trifenatate (JAN/USAN)
D09705  
Bepotastine (USAN/INN)
D09717  
Preladenant (USAN/INN)
D09724  
Afatinib (USAN/INN)
D09732  
Ritobegron ethyl hydrochloride (JAN)
D09733  
Afatinib maleate (JAN)
D09752  
Carpronium chloride hydrate (JAN)
D09765  
Vorapaxar (USAN/INN)
D09766  
Vorapaxar sulfate (JAN/USAN)
D09774  
Imitrodast sodium (JAN)
D09784  
Garomefrine hydrochloride (JAN)
D09789  
Kirenidipine hydrochloride (JAN)
D09794  
Norepinephrine hydrochloride (JAN)
D09797  
Cargutocin (INN/JAN)
D09808  
Carbinoxamine diphenyldisulfonate (JAN)
D09819  
Chlorpromazine tannate (JAN)
D09820  
Vasopressin tannate (JAN)
D09842  
dl-Methylephedrine saccharinate (JAN)
D09845  
Montirelin hydrate (JAN)
D09866  
Atopaxar (USAN)
D09867  
Atopaxar hydrobromide (USAN)
D09883  
Dacomitinib (USAN/INN)
D09919  
Lenvatinib (USAN/INN)
D09920  
Lenvatinib mesilate (JAN)
D09933  
Naronapride (USAN/INN)
D09934  
Naronapride dihydrochloride (USAN)
D09939  
Olaratumab (USAN/INN)
D09976  
Temanogrel (USAN/INN)
D09977  
Temanogrel hydrochloride (USAN)
D09980  
Trastuzumab emtansine (genetical recombination) (JAN)
D09991  
Vipadenant (USAN/INN)
D10006  
Eplivanserin (USAN/INN)
D10018  
Necitumumab (USAN/INN)
D10020  
Olodaterol hydrochloride (JAN/USAN)
D10031  
Zalutumumab (USAN/INN)
D10062  
Cabozantinib (USAN)
D10099  
Cerlapirdine (USAN)
D10100  
Cerlapirdine hydrochloride (USAN)
D10102  
Crenolanib (USAN)
D10103  
Crenolanib besylate (USAN)
D10117  
Epelsiban (USAN)
D10118  
Epelsiban besylate (USAN)
D10135  
Macitentan (JAN/USAN)
D10137  
Regorafenib hydrate (JAN)
D10138  
Regorafenib (USAN/INN)
D10145  
Olodaterol (USAN/INN)
D10152  
Prucalopride succinate (USAN)
D10174  
Tozadenant (USAN)
D10180  
Umeclidinium (USAN)
D10181  
Umeclidinium bromide (JAN/USAN)
D10184  
Vortioxetine (USAN)
D10185  
Vortioxetine hydrobromide (JAN/USAN)
D10219  
Abediterol (USAN/INN)
D10220  
Abediterol napadisylate (USAN)
D10364  
Aripiprazole lauroxil (USAN)
D10386  
Cindunistat (USAN/INN)
D10391  
Telmapitant (USAN)
D10419  
Cindunistat hydrochloride maleate (USAN)
D10514  
Dacomitinib hydrate (JAN)
D10516  
Aripiprazole hydrate (JAN)
Other DBs
BSID: 
GO: 
Organism
Homo sapiens (human) [GN:hsa]
Gene
6546  
SLC8A1; solute carrier family 8 (sodium/calcium exchanger), member 1 [KO:K05849]
6543  
SLC8A2; solute carrier family 8 (sodium/calcium exchanger), member 2 [KO:K05849]
6547  
SLC8A3; solute carrier family 8 (sodium/calcium exchanger), member 3 [KO:K05849]
490  
ATP2B1; ATPase, Ca++ transporting, plasma membrane 1 [KO:K05850] [EC:3.6.3.8]
492  
ATP2B3; ATPase, Ca++ transporting, plasma membrane 3 [KO:K05850] [EC:3.6.3.8]
493  
ATP2B4; ATPase, Ca++ transporting, plasma membrane 4 [KO:K05850] [EC:3.6.3.8]
491  
ATP2B2; ATPase, Ca++ transporting, plasma membrane 2 [KO:K05850] [EC:3.6.3.8]
1128  
CHRM1; cholinergic receptor, muscarinic 1 [KO:K04129]
1131  
CHRM3; cholinergic receptor, muscarinic 3 [KO:K04131]
1133  
CHRM5; cholinergic receptor, muscarinic 5 [KO:K04133]
135  
ADORA2A; adenosine A2a receptor [KO:K04266]
136  
ADORA2B; adenosine A2b receptor [KO:K04267]
153  
ADRB1; adrenoceptor beta 1 [KO:K04141]
154  
ADRB2; adrenoceptor beta 2, surface [KO:K04142]
155  
ADRB3; adrenoceptor beta 3 [KO:K04143]
1812  
DRD1; dopamine receptor D1 [KO:K04144]
1816  
DRD5; dopamine receptor D5 [KO:K05840]
3274  
HRH2; histamine receptor H2 [KO:K04150]
3360  
HTR4; 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled [KO:K04160]
3361  
HTR5A; 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled [KO:K04161]
3362  
HTR6; 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled [KO:K04162]
3363  
HTR7; 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled [KO:K04163]
2778  
GNAS; GNAS complex locus [KO:K04632]
2774  
GNAL; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type [KO:K04633]
107  
ADCY1; adenylate cyclase 1 (brain) [KO:K08041] [EC:4.6.1.1]
108  
ADCY2; adenylate cyclase 2 (brain) [KO:K08042] [EC:4.6.1.1]
109  
ADCY3; adenylate cyclase 3 [KO:K08043] [EC:4.6.1.1]
196883  
ADCY4; adenylate cyclase 4 [KO:K08044] [EC:4.6.1.1]
113  
ADCY7; adenylate cyclase 7 [KO:K08047] [EC:4.6.1.1]
114  
ADCY8; adenylate cyclase 8 (brain) [KO:K08048] [EC:4.6.1.1]
115  
ADCY9; adenylate cyclase 9 [KO:K08049] [EC:4.6.1.1]
5566  
PRKACA; protein kinase, cAMP-dependent, catalytic, alpha [KO:K04345] [EC:2.7.11.11]
5567  
PRKACB; protein kinase, cAMP-dependent, catalytic, beta [KO:K04345] [EC:2.7.11.11]
5568  
PRKACG; protein kinase, cAMP-dependent, catalytic, gamma [KO:K04345] [EC:2.7.11.11]
5613  
PRKX; protein kinase, X-linked [KO:K04345] [EC:2.7.11.11]
5350  
PLN; phospholamban [KO:K05852]
487  
ATP2A1; ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 [KO:K05853] [EC:3.6.3.8]
489  
ATP2A3; ATPase, Ca++ transporting, ubiquitous [KO:K05853] [EC:3.6.3.8]
488  
ATP2A2; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [KO:K05853] [EC:3.6.3.8]
6786  
STIM1; stromal interaction molecule 1 [KO:K16059]
57620  
STIM2; stromal interaction molecule 2 [KO:K18196]
84876  
ORAI1; ORAI calcium release-activated calcium modulator 1 [KO:K16056]
80228  
ORAI2; ORAI calcium release-activated calcium modulator 2 [KO:K16057]
93129  
ORAI3; ORAI calcium release-activated calcium modulator 3 [KO:K16058]
775  
CACNA1C; calcium channel, voltage-dependent, L type, alpha 1C subunit [KO:K04850]
776  
CACNA1D; calcium channel, voltage-dependent, L type, alpha 1D subunit [KO:K04851]
778  
CACNA1F; calcium channel, voltage-dependent, L type, alpha 1F subunit [KO:K04853]
779  
CACNA1S; calcium channel, voltage-dependent, L type, alpha 1S subunit [KO:K04857]
773  
CACNA1A; calcium channel, voltage-dependent, P/Q type, alpha 1A subunit [KO:K04344]
774  
CACNA1B; calcium channel, voltage-dependent, N type, alpha 1B subunit [KO:K04849]
777  
CACNA1E; calcium channel, voltage-dependent, R type, alpha 1E subunit [KO:K04852]
8913  
CACNA1G; calcium channel, voltage-dependent, T type, alpha 1G subunit [KO:K04854]
8912  
CACNA1H; calcium channel, voltage-dependent, T type, alpha 1H subunit [KO:K04855]
8911  
CACNA1I; calcium channel, voltage-dependent, T type, alpha 1I subunit [KO:K04856]
1139  
CHRNA7; cholinergic receptor, nicotinic, alpha 7 (neuronal) [KO:K04809]
5023  
P2RX1; purinergic receptor P2X, ligand-gated ion channel, 1 [KO:K05215]
22953  
P2RX2; purinergic receptor P2X, ligand-gated ion channel, 2 [KO:K05216]
5024  
P2RX3; purinergic receptor P2X, ligand-gated ion channel, 3 [KO:K05217]
5025  
P2RX4; purinergic receptor P2X, ligand-gated ion channel, 4 [KO:K05218]
5026  
P2RX5; purinergic receptor P2X, ligand-gated ion channel, 5 [KO:K05219]
5027  
P2RX7; purinergic receptor P2X, ligand-gated ion channel, 7 [KO:K05220]
9127  
P2RX6; purinergic receptor P2X, ligand-gated ion channel, 6 [KO:K05221]
2902  
GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1 [KO:K05208]
2903  
GRIN2A; glutamate receptor, ionotropic, N-methyl D-aspartate 2A [KO:K05209]
2905  
GRIN2C; glutamate receptor, ionotropic, N-methyl D-aspartate 2C [KO:K05211]
2906  
GRIN2D; glutamate receptor, ionotropic, N-methyl D-aspartate 2D [KO:K05212]
6261  
RYR1; ryanodine receptor 1 (skeletal) [KO:K04961]
6262  
RYR2; ryanodine receptor 2 (cardiac) [KO:K04962]
6263  
RYR3; ryanodine receptor 3 [KO:K04963]
10800  
CYSLTR1; cysteinyl leukotriene receptor 1 [KO:K04322]
57105  
CYSLTR2; cysteinyl leukotriene receptor 2 [KO:K04323]
1129  
CHRM2; cholinergic receptor, muscarinic 2 [KO:K04130]
148  
ADRA1A; adrenoceptor alpha 1A [KO:K04135]
147  
ADRA1B; adrenoceptor alpha 1B [KO:K04136]
146  
ADRA1D; adrenoceptor alpha 1D [KO:K04137]
185  
AGTR1; angiotensin II receptor, type 1 [KO:K04166]
1909  
EDNRA; endothelin receptor type A [KO:K04197]
1910  
EDNRB; endothelin receptor type B [KO:K04198]
2149  
F2R; coagulation factor II (thrombin) receptor [KO:K03914]
2911  
GRM1; glutamate receptor, metabotropic 1 [KO:K04603]
2915  
GRM5; glutamate receptor, metabotropic 5 [KO:K04604]
2925  
GRPR; gastrin-releasing peptide receptor [KO:K04169]
3269  
HRH1; histamine receptor H1 [KO:K04149]
3356  
HTR2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled [KO:K04157]
3357  
HTR2B; 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled [KO:K04157]
3358  
HTR2C; 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled [KO:K04157]
3973  
LHCGR; luteinizing hormone/choriogonadotropin receptor [KO:K04248]
4923  
NTSR1; neurotensin receptor 1 (high affinity) [KO:K04211]
5021  
OXTR; oxytocin receptor [KO:K04229]
552  
AVPR1A; arginine vasopressin receptor 1A [KO:K04226]
553  
AVPR1B; arginine vasopressin receptor 1B [KO:K04227]
56413  
LTB4R2; leukotriene B4 receptor 2 [KO:K04297]
5724  
PTAFR; platelet-activating factor receptor [KO:K04279]
5731  
PTGER1; prostaglandin E receptor 1 (subtype EP1), 42kDa [KO:K04258]
5733  
PTGER3; prostaglandin E receptor 3 (subtype EP3) [KO:K04260]
5737  
PTGFR; prostaglandin F receptor (FP) [KO:K04262]
623  
BDKRB1; bradykinin receptor B1 [KO:K03915]
624  
BDKRB2; bradykinin receptor B2 [KO:K03916]
6869  
TACR1; tachykinin receptor 1 [KO:K04222]
6865  
TACR2; tachykinin receptor 2 [KO:K04223]
6870  
TACR3; tachykinin receptor 3 [KO:K04224]
6915  
TBXA2R; thromboxane A2 receptor [KO:K04264]
7201  
TRHR; thyrotropin-releasing hormone receptor [KO:K04282]
886  
CCKAR; cholecystokinin A receptor [KO:K04194]
887  
CCKBR; cholecystokinin B receptor [KO:K04195]
1956  
EGFR; epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
2064  
ERBB2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 [KO:K05083] [EC:2.7.10.1]
2065  
ERBB3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 [KO:K05084] [EC:2.7.10.1]
2066  
ERBB4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 [KO:K05085] [EC:2.7.10.1]
5156  
PDGFRA; platelet-derived growth factor receptor, alpha polypeptide [KO:K04363] [EC:2.7.10.1]
5159  
PDGFRB; platelet-derived growth factor receptor, beta polypeptide [KO:K05089] [EC:2.7.10.1]
2776  
GNAQ; guanine nucleotide binding protein (G protein), q polypeptide [KO:K04634]
2767  
GNA11; guanine nucleotide binding protein (G protein), alpha 11 (Gq class) [KO:K04635]
9630  
GNA14; guanine nucleotide binding protein (G protein), alpha 14 [KO:K04636]
2769  
GNA15; guanine nucleotide binding protein (G protein), alpha 15 (Gq class) [KO:K04637]
5333  
PLCD1; phospholipase C, delta 1 [KO:K05857] [EC:3.1.4.11]
113026  
PLCD3; phospholipase C, delta 3 [KO:K05857] [EC:3.1.4.11]
84812  
PLCD4; phospholipase C, delta 4 [KO:K05857] [EC:3.1.4.11]
23236  
PLCB1; phospholipase C, beta 1 (phosphoinositide-specific) [KO:K05858] [EC:3.1.4.11]
5330  
PLCB2; phospholipase C, beta 2 [KO:K05858] [EC:3.1.4.11]
5331  
PLCB3; phospholipase C, beta 3 (phosphatidylinositol-specific) [KO:K05858] [EC:3.1.4.11]
5332  
PLCB4; phospholipase C, beta 4 [KO:K05858] [EC:3.1.4.11]
5335  
PLCG1; phospholipase C, gamma 1 [KO:K01116] [EC:3.1.4.11]
5336  
PLCG2; phospholipase C, gamma 2 (phosphatidylinositol-specific) [KO:K05859] [EC:3.1.4.11]
51196  
PLCE1; phospholipase C, epsilon 1 [KO:K05860] [EC:3.1.4.11]
89869  
PLCZ1; phospholipase C, zeta 1 [KO:K05861] [EC:3.1.4.11]
3708  
ITPR1; inositol 1,4,5-trisphosphate receptor, type 1 [KO:K04958]
3709  
ITPR2; inositol 1,4,5-trisphosphate receptor, type 2 [KO:K04959]
3710  
ITPR3; inositol 1,4,5-trisphosphate receptor, type 3 [KO:K04960]
952  
CD38; CD38 molecule [KO:K01242] [EC:2.4.99.20 3.2.2.6]
8877  
SPHK1; sphingosine kinase 1 [KO:K04718] [EC:2.7.1.91]
56848  
SPHK2; sphingosine kinase 2 [KO:K04718] [EC:2.7.1.91]
7416  
VDAC1; voltage-dependent anion channel 1 [KO:K05862]
7417  
VDAC2; voltage-dependent anion channel 2 [KO:K15040]
7419  
VDAC3; voltage-dependent anion channel 3 [KO:K15041]
291  
SLC25A4; solute carrier family 25 (mitochondrial carrier [KO:K05863]
292  
SLC25A5; solute carrier family 25 (mitochondrial carrier [KO:K05863]
293  
SLC25A6; solute carrier family 25 (mitochondrial carrier [KO:K05863]
83447  
SLC25A31; solute carrier family 25 (mitochondrial carrier [KO:K05863]
10105  
PPIF; peptidylprolyl isomerase F [KO:K09565] [EC:5.2.1.8]
7134  
TNNC1; troponin C type 1 (slow) [KO:K05865]
7125  
TNNC2; troponin C type 2 (fast) [KO:K12042]
810  
CALML3; calmodulin-like 3 [KO:K02183]
805  
CALM2; calmodulin 2 (phosphorylase kinase, delta) [KO:K02183]
808  
CALM3; calmodulin 3 (phosphorylase kinase, delta) [KO:K02183]
801  
CALM1; calmodulin 1 (phosphorylase kinase, delta) [KO:K02183]
163688  
CALML6; calmodulin-like 6 [KO:K02183]
51806  
CALML5; calmodulin-like 5 [KO:K02183]
5260  
PHKG1; phosphorylase kinase, gamma 1 (muscle) [KO:K00871] [EC:2.7.11.19]
5261  
PHKG2; phosphorylase kinase, gamma 2 (testis) [KO:K00871] [EC:2.7.11.19]
5257  
PHKB; phosphorylase kinase, beta [KO:K07190]
5256  
PHKA2; phosphorylase kinase, alpha 2 (liver) [KO:K07190]
5255  
PHKA1; phosphorylase kinase, alpha 1 (muscle) [KO:K07190]
4638  
MYLK; myosin light chain kinase [KO:K00907] [EC:2.7.11.18]
85366  
MYLK2; myosin light chain kinase 2 [KO:K00907] [EC:2.7.11.18]
91807  
MYLK3; myosin light chain kinase 3 [KO:K00907] [EC:2.7.11.18]
340156  
MYLK4; myosin light chain kinase family, member 4 [KO:K00907] [EC:2.7.11.18]
815  
CAMK2A; calcium/calmodulin-dependent protein kinase II alpha [KO:K04515] [EC:2.7.11.17]
817  
CAMK2D; calcium/calmodulin-dependent protein kinase II delta [KO:K04515] [EC:2.7.11.17]
816  
CAMK2B; calcium/calmodulin-dependent protein kinase II beta [KO:K04515] [EC:2.7.11.17]
818  
CAMK2G; calcium/calmodulin-dependent protein kinase II gamma [KO:K04515] [EC:2.7.11.17]
814  
CAMK4; calcium/calmodulin-dependent protein kinase IV [KO:K05869] [EC:2.7.11.17]
5530  
PPP3CA; protein phosphatase 3, catalytic subunit, alpha isozyme [KO:K04348] [EC:3.1.3.16]
5532  
PPP3CB; protein phosphatase 3, catalytic subunit, beta isozyme [KO:K04348] [EC:3.1.3.16]
5533  
PPP3CC; protein phosphatase 3, catalytic subunit, gamma isozyme [KO:K04348] [EC:3.1.3.16]
5534  
PPP3R1; protein phosphatase 3, regulatory subunit B, alpha [KO:K06268]
5535  
PPP3R2; protein phosphatase 3, regulatory subunit B, beta [KO:K06268]
4842  
NOS1; nitric oxide synthase 1 (neuronal) [KO:K13240] [EC:1.14.13.39]
4843  
NOS2; nitric oxide synthase 2, inducible [KO:K13241] [EC:1.14.13.39]
4846  
NOS3; nitric oxide synthase 3 (endothelial cell) [KO:K13242] [EC:1.14.13.39]
5136  
PDE1A; phosphodiesterase 1A, calmodulin-dependent [KO:K13755] [EC:3.1.4.17]
5153  
PDE1B; phosphodiesterase 1B, calmodulin-dependent [KO:K13755] [EC:3.1.4.17]
5137  
PDE1C; phosphodiesterase 1C, calmodulin-dependent 70kDa [KO:K13755] [EC:3.1.4.17]
2185  
PTK2B; protein tyrosine kinase 2 beta [KO:K05871] [EC:2.7.10.2]
3707  
ITPKB; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
3706  
ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
80271  
ITPKC; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
5578  
PRKCA; protein kinase C, alpha [KO:K02677] [EC:2.7.11.13]
5579  
PRKCB; protein kinase C, beta [KO:K02677] [EC:2.7.11.13]
5582  
PRKCG; protein kinase C, gamma [KO:K02677] [EC:2.7.11.13]
Compound
C00002  
ATP
C00004  
NADH
C00076  
Calcium cation
C00165  
Diacylglycerol
C00575  
3',5'-Cyclic AMP
C01245  
D-myo-Inositol 1,4,5-trisphosphate
C01330  
Sodium cation
C06124  
Sphingosine 1-phosphate
C13050  
Cyclic ADP-ribose
C13051  
Nicotinic acid adenine dinucleotide phosphate
Reference
  Authors
Berridge MJ, Bootman MD, Roderick HL.
  Title
Calcium signalling: dynamics, homeostasis and remodelling.
  Journal
Nat Rev Mol Cell Biol 4:517-29 (2003)
Reference
  Authors
Berridge MJ, Lipp P, Bootman MD.
  Title
The versatility and universality of calcium signalling.
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Nat Rev Mol Cell Biol 1:11-21 (2000)
Reference
  Authors
Wang MC, Dolphin A, Kitmitto A.
  Title
L-type voltage-gated calcium channels: understanding function through structure.
  Journal
FEBS Lett 564:245-50 (2004)
Reference
  Authors
Ferrier GR, Howlett SE.
  Title
Cardiac excitation-contraction coupling: role of membrane potential in regulation of contraction.
  Journal
Am J Physiol Heart Circ Physiol 280:H1928-44 (2001)
Reference
  Authors
Keef KD, Hume JR, Zhong J.
  Title
Regulation of cardiac and smooth muscle Ca(2+) channels (Ca(V)1.2a,b) by protein kinases.
  Journal
Am J Physiol Cell Physiol 281:C1743-56 (2001)
Reference
PMID:8125957
  Authors
Hell JW, Appleyard SM, Yokoyama CT, Warner C, Catterall WA.
  Title
Differential phosphorylation of two size forms of the N-type calcium channel alpha 1 subunit which have different COOH termini.
  Journal
J Biol Chem 269:7390-6 (1994)
Reference
  Authors
Yunker AM.
  Title
Modulation and pharmacology of low voltage-activated ("T-Type") calcium channels.
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J Bioenerg Biomembr 35:577-98 (2003)
Reference
PMID:9149541
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Yakel JL.
  Title
Calcineurin regulation of synaptic function: from ion channels to transmitter release and gene transcription.
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Trends Pharmacol Sci 18:124-34 (1997)
Reference
  Authors
Fukunaga K, Miyamoto E.
  Title
A working model of CaM kinase II activity in hippocampal long-term potentiation and memory.
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Neurosci Res 38:3-17 (2000)
Reference
PMID:9235901
  Authors
Della Rocca GJ, van Biesen T, Daaka Y, Luttrell DK, Luttrell LM, Lefkowitz RJ.
  Title
Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase.
  Journal
J Biol Chem 272:19125-32 (1997)
Reference
PMID:7861177
  Authors
Furuichi T, Mikoshiba K.
  Title
Inositol 1, 4, 5-trisphosphate receptor-mediated Ca2+ signaling in the brain.
  Journal
J Neurochem 64:953-60 (1995)
Reference
  Authors
Bruce JI, Straub SV, Yule DI.
  Title
Crosstalk between cAMP and Ca2+ signaling in non-excitable cells.
  Journal
Cell Calcium 34:431-44 (2003)
Reference
  Authors
Lee HC, Munshi C, Graeff R.
  Title
Structures and activities of cyclic ADP-ribose, NAADP and their metabolic enzymes.
  Journal
Mol Cell Biochem 193:89-98 (1999)
Reference
  Authors
Crompton M.
  Title
Mitochondrial intermembrane junctional complexes and their role in cell death.
  Journal
J Physiol 529 Pt 1:11-21 (2000)
Reference
  Authors
Grewal SS, York RD, Stork PJ.
  Title
Extracellular-signal-regulated kinase signalling in neurons.
  Journal
Curr Opin Neurobiol 9:544-53 (1999)
Reference
  Authors
Trushin SA, Pennington KN, Carmona EM, Asin S, Savoy DN, Billadeau DD, Paya CV.
  Title
Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes.
  Journal
Mol Cell Biol 23:7068-81 (2003)
Reference
  Authors
Hutchins JR, Dikovskaya D, Clarke PR.
  Title
Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca(2+)/calmodulin-dependent protein [corrected] kinase II.
  Journal
Mol Biol Cell 14:4003-14 (2003)
Reference
  Authors
Tornquist K
  Title
Sphingosine 1-phosphate, sphingosine kinase and autocrine calcium signalling in thyroid cells.
  Journal
Acta Physiol (Oxf) 204:151-7 (2012)
Reference
  Authors
Feske S
  Title
Immunodeficiency due to defects in store-operated calcium entry.
  Journal
Ann N Y Acad Sci 1238:74-90 (2011)
Reference
  Authors
Giachini FR, Lima VV, Hannan JL, Carneiro FS, Webb RC, Tostes RC
  Title
STIM1/Orai1-mediated store-operated Ca2+ entry: the tip of the iceberg.
  Journal
Braz J Med Biol Res 44:1080-7 (2011)
Reference
  Authors
Baba Y, Kurosaki T
  Title
[Regulation of store-operated calcium entry by STIM1].
  Journal
Seikagaku 80:1123-8 (2008)
KO pathway
 

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