KEGG T01001: 10125

Homo sapiens (human): 10125

Entry

10125 CDS T01001

Gene name

RASGRP1, CALDAG-GEFI, CALDAG-GEFII, RASGRP, V, hRasGRP1

Definition

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

Orthology

K04350

RAS guanyl-releasing protein 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04010	MAPK signaling pathway
hsa04660	T cell receptor signaling pathway

Class

Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:hsa04010]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:hsa04660]

SSDB

Motif

Pfam:

RasGEF C1_1 RasGEF_N EF-hand_7 EF-hand_6 EF-hand_1 EF-hand_5 EF-hand_8 MENTAL DUF2968 bZIP_1

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

15q14

AA seq 762 aa
MGTLGKAREAPRKPSHGCRAASKARLEAKPANSPFPSHPSLAHITQFRMMVSLGHLAKGA
SLDDLIDSCIQSFDADGNLCRSNQLLQVMLTMHRIVISSAELLQKVITLYKDALAKNSPG
LCLKICYFVRYWITEFWVMFKMDASLTDTMEEFQELVKAKGEELHCRLIDTTQINARDWS
RKLTQRIKSNTSKKRKVSLLFDHLEPEELSEHLTYLEFKSFRRISFSDYQNYLVNSCVKE
NPTMERSIALCNGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGG
LCHSSISRLKETSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDFKIPILGVHLK
DLISLYEAMPDYLEDGKVNVHKLLALYNHISELVQLQEVAPPLEANKDLVHLLTLSLDLY
YTEDEIYELSYAREPRNHRAPSVFKNYDHDQDGYISQEEFEKIAASFPFSFCVMDKDREG
LISRDEITAYFMRASSIYSKLGLGFPHNFQETTYLKPTFCDNCAGFLWGVIKQGYRCKDC
GMNCHKQCKDLVVFECKKRAKNPVAPTENNTSVGPVSNLCSLGAKDLLHAPEEGPFTFPN
GEAVEHGEESKDRTIMLMGVSSQKISLRLKRAVAHKATQTESQPWIGSEGPSGPFVLSSP
RKTAQDTLYVLPSPTSPCPSPVLVRKRAFVKWENKDSLIKSKEELRHLRLPTYQELEQEI
NTLKADNDALKIQLKYAQKKIESLQLEKSNHVLAQMEQGDCS

NT seq 2289 nt +upstreamnt +downstreamnt
atgggcaccctgggcaaggcgagagaggctccgcggaaaccttcccatggctgcagagct
gcctctaaagcaagactagaggcaaagccagccaacagccccttcccctcccatcccagc
ttggcccacatcacccagttccgaatgatggtgtctctgggacatttagccaaaggagcc
agcctggacgatctcattgacagctgcattcaatcttttgatgcagatggaaacctgtgt
cgaagtaaccaactgttgcaagtcatgctgaccatgcaccgaattgtcatctcctctgca
gaactgctccaaaaagttatcaccctctataaggatgctttggcaaagaattcaccagga
ctttgcctgaagatctgttattttgtaaggtattggataacagaattctgggtcatgttt
aaaatggacgccagcttgacagacactatggaggagtttcaggaactggtgaaagctaag
ggtgaggagttacattgccgcctgattgacacaactcaaatcaatgcccgtgactggtcc
aggaaacttactcaaaggataaaatcaaataccagcaagaaacggaaagtctccctgctc
tttgaccatctggaaccagaagagctatccgagcacctcacctaccttgagttcaagtct
ttccggaggatatcgttctctgattatcagaattaccttgtaaatagctgtgtgaaggaa
aaccccaccatggagcgatctattgctctgtgcaacggcatctcccagtgggtacaactg
atggttctcagccgccccacgccgcagctccgagcagaagtcttcatcaagttcatccag
gtggctcagaagctccaccaactacagaacttcaatacactgatggctgtgataggtggg
ctgtgtcacagctcaatctcgaggctcaaggagacaagttcgcatgtcccacatgaaatc
aataaggttctcggtgagatgactgagctgctgtcctcctccagaaactacgacaattac
cggcgagcctatggagagtgcaccgacttcaagatccccattctgggtgtgcatctcaag
gacctcatctccctgtatgaagccatgcctgactatctggaggacgggaaagtgaacgtc
cataagctactggccctatacaatcatatcagtgaattggtccagctgcaagaggtggcc
ccacccttggaggctaacaaggacttggtacacttgctgacgttatccctggatctttac
tacactgaggatgaaatctatgagctttcctatgcccgggaaccaaggaaccacagagct
ccatctgtcttcaagaactatgatcacgaccaggatggatacatttctcaggaagaattt
gaaaagattgctgcgagttttccattttccttctgtgtgatggacaaagacagggaaggc
ctcatcagcagggatgagatcacagcctacttcatgagagccagctcaatctattccaag
ctgggcctgggctttcctcacaacttccaagagaccacctacctgaagcccactttttgt
gacaactgtgctggatttctctggggagtgatcaaacaaggatatcgatgtaaagactgc
gggatgaactgtcacaaacaatgcaaagatctggttgtgtttgagtgtaagaagcgagcc
aagaacccagtagctcccacagagaacaacacttctgtggggccagtgtccaacctttgc
tcattgggagccaaagatctgctccatgcacctgaggaaggaccttttacattccctaat
ggggaggctgtggaacatggtgaggagagtaaggatcggaccatcatgctgatgggagtg
tcctcacagaagatttctcttcggctgaagagggctgttgcccacaaggccacccagact
gaatcacagccttggattggcagtgagggcccttcaggtccctttgtgctgtcttcccca
aggaagacagcccaggatactctatatgtgcttcccagtcccacctctccatgtcctagc
ccagtcttggtcagaaagcgggcttttgtcaagtgggagaataaagactccctcataaaa
tcaaaggaggagctccgtcacctcagactgcctacctaccaagaactggaacaggaaata
aatactctgaaagcagataatgatgccctaaagatccaactgaaatatgcacagaagaaa
atagaatccctccagcttgaaaaaagcaatcatgtcttagctcaaatggagcagggtgac
tgttcttag

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (17)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (42)   
   RefSeq(nuc) (2)   
   GenBank (20)   
   EMBL (20)   
Protein domain (11)   
   Pfam (11)   
All databases (86)   

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