KEGG T01001: 10411

Homo sapiens (human): 10411

Entry

10411 CDS T01001

Gene name

RAPGEF3, CAMP-GEFI, EPAC, EPAC1, HSU79275, bcm910

Definition

Rap guanine nucleotide exchange factor (GEF) 3

Orthology

K08014

Rap guanine nucleotide exchange factor (GEF) 3

Organism

hsa Homo sapiens (human)

Pathway

hsa04670	Leukocyte transendothelial migration
hsa04720	Long-term potentiation
hsa04726	Serotonergic synapse

Class

Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:hsa04670]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:hsa04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:hsa04720]

SSDB

Motif

Pfam:

RasGEF cNMP_binding RasGEF_N DEP

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

UniProt:

Position

12q13.1

AA seq 923 aa
MKVGWPGESCWQVGLAVEDSPALGAPRVGALPDVVPEGTLLNMVLRRMHRPRSCSYQLLL
EHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRK
YHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQ
FYRFPGPEPEPVGTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEEL
LHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGL
VTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHG
KVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSD
FLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSML
HTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWL
PNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQV
LVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDL
VSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVAT
ELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKV
RKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFE
KMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWA
YVQQLKVIDNQRELSRLSRELEP

NT seq 2772 nt +upstreamnt +downstreamnt
atgaaggtgggctggccaggtgagagctgctggcaggtgggcctggctgtggaggatagc
ccagctctgggagcaccgcgggtgggagccctccctgacgtggtgccggaggggacacta
ctcaacatggtgttgagaaggatgcaccggccccgaagctgctcctaccagctgctgctg
gagcaccagcgtccgagctgcatccaggggctgcgctggacaccactcaccaacagcgag
gagtccctggatttcagcgagagcctggagcaggcctccacagagcgggtgctcagggct
gggaggcagctgcatcggcatctgctggccacctgcccaaacctcatccgagaccggaag
taccaccttaggctctatcggcagtgctgctctggccgggagctggtggatgggatcttg
gccctgggacttggggtccattcccggagccaagttgtgggaatctgccaggtgctgctg
gatgaaggtgccctctgccatgtgaaacacgactgggccttccaggaccgagatgcccaa
ttctaccggttccccgggcccgagcccgagcccgtgggaactcatgagatggaggaggag
ttggccgaagctgtggccctgctctcccagcgggggcctgacgccctgctcactgtggca
cttcgaaagcccccaggtcagcgcacggatgaagagctggacctcatctttgaggagctg
ctgcacatcaaggctgtggcccacctctccaactcggtgaagcgagaattagcggctgtt
ctgctctttgaaccacacagcaaggcagggaccgtgttgttcagccagggggacaagggc
acttcgtggtacattatctggaagggatctgtcaacgtggtgacccatggcaaggggctg
gtgaccaccctgcatgagggagatgattttggacagctggctctggtgaatgatgcaccc
cgggcagccaccatcatcctgcgagaagacaactgtcatttcctgcgtgtggacaagcag
gacttcaaccgtatcatcaaggatgtggaggcaaagaccatgcggctggaagaacatggc
aaagtggtgctggtgctggagagagcctctcagggcgccggcccttcccgacccccaacc
ccaggcaggaaccggtatacagtgatgtctggcaccccagagaagatcctagagcttctg
ttggaggccatgggaccagattccagtgctcatgacccaacagagacattcctcagcgac
ttcctcctgacccacagggtcttcatgcccagcgcccaactctgcgctgcccttctgcac
cacttccatgtggagcctgcgggtggcagcgagcaggagcgcagcacctacgtctgcaac
aagaggcagcagatcttgcggctggtcagccagtgggtggccctgtatggctccatgctc
cacactgaccctgtggccaccagcttcctccagaaactctcagacctggtgggcagggac
acccgactcagcaacctgctgagggagcagtggccagagaggcggcgatgccacaggttg
gagaatggctgtgggaatgcatctcctcagatgaaggcccggaacttgcctgtttggctc
cccaaccaggacgagccccttcctggcagcagctgtgccatccaagttggggataaagtc
ccctatgacatctgccggccagaccactcagtgttgaccctgcagctgcctgtgacagcc
tccgtgagagaggtgatggcagcgttggcccaggaggatggctggaccaaggggcaggtg
ctggtgaaggtcaattctgcaggtgatgccattggcctgcagccagatgcccgtggtgtg
gccacatctctggggctcaatgagcgtctctttgttgtcaacccacaggaagtgcatgag
ctgatcccacaccctgaccagctggggcccactgtgggctctgctgaggggctggacctg
gtgagtgccaaggacctggcaggccagctgacggaccacgactggagcctcttcaacagt
atccaccaggtggagctgatccactatgtgctgggcccccagcatctgcgggatgtcacc
accgccaacctggagcgcttcatgcgccgcttcaatgagctgcagtactgggtggccacc
gagctgtgtctctgccccgtgcccggcccccgggcccagctgctcaggaagttcattaag
ctggcggcccacctcaaggagcagaagaatctcaattccttctttgccgtcatgtttggc
ctcagcaactcggccatcagccgcctagcccacacctgggagcggctgcctcacaaagtc
cggaagctgtactccgccctcgagaggctgctggatccctcatggaaccaccgggtatac
cgactggccctcgccaagctctcccctcctgtcatccccttcatgccccttcttctcaaa
gacatgaccttcattcatgagggaaaccacacactagtggagaatctcatcaactttgag
aagatgagaatgatggccagagccgcgcggatgctgcaccactgccgaagccacaaccct
gtgcctctctcaccactcagaagccgagtttcccacctccacgaggacagccaggtggcg
aggatttccacatgctcggagcagtccctgagcacccggagtccagccagcacctgggct
tatgtccagcagctgaaggtcattgacaaccagcgggaactctcccgcctctcccgagag
ctggagccatga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (13)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   RefSeq(pep) (3)   
DNA sequence (51)   
   RefSeq(nuc) (3)   
   GenBank (24)   
   EMBL (24)   
Protein domain (4)   
   Pfam (4)   
All databases (85)   

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