KEGG T01001: 10603

Homo sapiens (human): 10603

Entry

10603 CDS T01001

Gene name

SH2B2, APS

Definition

SH2B adaptor protein 2

Orthology

K07193

SH2B adapter protein 2

Organism

hsa Homo sapiens (human)

Pathway

hsa04722	Neurotrophin signaling pathway
hsa04910	Insulin signaling pathway

Class

Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:hsa04910]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:hsa04722]

SSDB

Motif

Pfam:

Phe_ZIP SH2 PH PH_9

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

UniProt:

Structure

PDB:

1Q2H

Position

7q22

AA seq 675 aa
MDPSYCPAHGFPSQDPLWPLSSQQWSSAHYSEPAAGGCDGTEAMNGAGPGPAAAAPVPVP
VPVPDWRQFCELHAQAAAVDFAHKFCRFLRDNPAYDTPDAGASFSRHFAANFLDVFGEEV
RRVLVAGPTTRGAAVSAEAMEPELADTSALKAAPYGHSRSSEDVSTHAATKARVRKGFSL
RNMSLCVVDGVRDMWHRRASPEPDAAAAPRTAEPRDKWTRRLRLSRTLAAKVELVDIQRE
GALRFMVADDAAAGSGGSAQWQKCRLLLRRAVAEERFRLEFFVPPKASRPKVSIPLSAII
EVRTTMPLEMPEKDNTFVLKVENGAEYILETIDSLQKHSWVADIQGCVDPGDSEEDTELS
CTRGGCLASRVASCSCELLTDAVDLPRPPETTAVGAVVTAPHSRGRDAVRESLIHVPLET
FLQTLESPGGSGSDSNNTGEQGAETDPEAEPELELSDYPWFHGTLSRVKAAQLVLAGGPR
NHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQCHVQHLWFQSVLDMLRHFHTH
PIPLESGGSADITLRSYVRAQDPPPEPGPTPPAAPASPACWSDSPGQHYFSSLAAAACPP
ASPSDAAGASSSSASSSSAASGPAPPRPVEGQLSARSRSNSAERLLEAVAATAAEEPPEA
APGRARAVENQYSFY

NT seq 2028 nt +upstreamnt +downstreamnt
atggatccaagctattgtcctgcccatggcttcccatctcaggaccctctctggccgcta
tcatcccagcagtggagttcagcccactactctgaaccagccgcaggtggctgcgatggg
acggaagccatgaatggtgccggccctggccccgccgcagccgccccggtcccagtcccg
gtcccggtcccggactggcggcagttctgcgagctgcatgcgcaggcggccgccgtggac
tttgcgcacaagttctgccgtttcctgcgggacaacccagcttacgacacgcccgacgcc
ggcgcctccttctcccgccacttcgccgccaacttcctggacgtcttcggcgaggaggtg
cgccgcgtgctggtggctgggccgacgactcggggcgcggccgtgagcgcagaggccatg
gagccggagctcgcggacacctctgcactcaaggcggcgccctacggccactcgcggagc
tcggaggacgtgtccacgcacgcggccaccaaggcccgcgttcgcaagggcttctcgctg
cgcaacatgagcctgtgcgtggtggacggcgtgcgcgacatgtggcaccggcgcgcctcg
cccgagcccgacgcggcagctgccccgcgcaccgccgagccccgcgacaagtggacgcgg
cgcctgaggctgtcgcggacgctggctgccaaggtggagctggtggacattcaacgcgag
ggggcgctgcgcttcatggtggccgacgacgcggccgcgggctccgggggctcggctcag
tggcagaagtgccgcctgctcctgcgcagggctgtggccgaggaacgcttccgcctggag
ttcttcgtgccgcccaaagcctccaggcccaaggtcagcatcccactgtcagccatcatt
gaggtccgcaccaccatgcccctggaaatgccagagaaggataacacattcgtcctcaag
gtagagaatggagccgaatacatcttggagaccatcgactctctgcagaagcactcgtgg
gtagctgacatccagggctgcgtggaccccggtgacagtgaggaagacaccgagctctcc
tgtacccgaggaggctgtctggccagccgcgtggcctcctgcagctgtgagctcctgact
gatgcagtcgacctgccccgccccccagagacgacagccgtgggtgcagtggtgacagcc
ccccacagccgaggtcgagatgccgtcagagaatccctgatccacgtcccgctagagacc
tttctgcagaccctggaatccccgggcggcagcggcagtgacagcaataacacaggggaa
cagggtgcagagacggatcccgaggctgaacccgagctggagctatccgactacccatgg
ttccacgggacactgtcccgggtcaaggctgctcaactggttctggcaggggggccccgg
aaccacggcctcttcgtgatccgccaaagtgagactcggcctggggagtacgtgctgacc
ttcaacttccagggcaaggccaagcacctgcgcctgtccctgaacggccacggccagtgt
cacgtacagcatctgtggttccagtctgtgcttgacatgctccgccacttccacacacac
cccatcccactggagtcagggggctcggccgacatcacccttcgcagctatgtgcgggcc
caggaccccccaccagagccgggccccacgccccctgccgcgcccgcgtccccggcctgc
tggagcgactcgcccggccagcactacttctccagcctcgccgcggccgcctgcccgcct
gcctcgccctccgacgccgccggcgcctcctcgtcttccgcctcgtcgtcctctgccgcg
tcggggcccgcccccccgcgccccgtcgagggccagctcagcgcgcggagccgcagcaac
agcgccgagcgcctgctggaggccgtggccgccaccgccgccgaggagcccccggaggcc
gcgcccggccgcgcgcgcgccgtggagaaccagtactccttctactag

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (26)   

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