KEGG   Homo sapiens (human): 10788Help
Entry
10788             CDS       T01001                                 

Gene name
IQGAP2
Definition
(RefSeq) IQ motif containing GTPase activating protein 2
  KO
K05767  
Ras GTPase-activating-like protein IQGAP2/3
Organism
hsa  Homo sapiens (human)
Pathway
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    10788 (IQGAP2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Others
     10788 (IQGAP2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   10788 (IQGAP2)
  Exosomal proteins of colorectal cancer cells
   10788 (IQGAP2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
5q13.3
AA seq 1575 aa AA seqDB search
MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVEELP
PTTELEEGLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKKSGLHFRHTDNTVQWLRAM
ESIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEIS
NMRKELEKYGIQMPSFSKIGGILANELSVDEAALHAAVIAINEAVEKGIAEQTVVTLRNP
NAVLTLVDDNLAPEYQKELWDAKKKKEENARLKNSCISEEERDAYEELLTQAEIQGNINK
VNRQAAVDHINAVIPEGDPENTLLALKKPEAQLPAVYPFAAAMYQNELFNLQKQNTMNYL
AHEELLIAVEMLSAVALLNQALESNDLVSVQNQLRSPAIGLNNLDKAYVERYANTLLSVK
LEVLSQGQDNLSWNEIQNCIDMVNAQIQEENDRVVAVGYINEAIDEGNPLRTLETLLLPT
ANISDVDPAHAQHYQDVLYHAKSQKLGDSESVSKVLWLDEIQQAVDDANVDEDRAKQWVT
LVVDVNQCLEGKKSSDILSVLKSSTSNANDIIPECADKYYDALVKAKELKSERVSSDGSW
LKLNLHKKYDYYYNTDSKESSWVTPESCLYKESWLTGKEIEDIIEEVTVGYIRENIWSAS
EELLLRFQATSSGPILREEFEARKSFLHEQEENVVKIQAFWKGYKQRKEYMHRRQTFIDN
TDSIVKIQSWFRMATARKSYLSRLQYFRDHNNEIVKIQSLLRANKARDDYKTLVGSENPP
LTVIRKFVYLLDQSDLDFQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRI
TLEDVISHSKKLNKKKGGEMEILNNTDNQGIKSLSKERRKTLETYQQLFYLLQTNPLYLA
KLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTG
NPTVIKMVVSFNRGARGQNTLRQLLAPVVKEIIDDKSLIINTNPVEVYKAWVNQLETQTG
EASKLPYDVTTEQALTYPEVKNKLEASIENLRRVTDKVLNSIISSLDLLPYGLRYIAKVL
KNSIHEKFPDATEDELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSDQRRNLGS
VAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFKEACNVPEPEEKFNMDKYTDL
VTVSKPVIYISIEEIISTHSLLLEHQDAIAPEKNDLLSELLGSLGEVPTVESFLGEGAVD
PNDPNKANTLSQLSKTEISLVLTSKYDIEDGEAIDSRSLMIKTKKLIIDVIRNQPGNTLT
EILETPATAQQEVDHATDMVSRAMIDSRTPEEMKHSQSMIEDAQLPLEQKKRKIQRNLRT
LEQTGHVSSENKYQDILNEIAKDIRNQRIYRKLRKAELAKLQQTLNALNKKAAFYEEQIN
YYDTYIKTCLDNLKRKNTRRSIKLDGKGEPKGAKRAKPVKYTAAKLHEKGVLLDIDDLQT
NQFKNVTFDIIATEDVGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVMKMFDKVKVN
VNLLIYLLNKKFYGK
NT seq 4728 nt NT seq  +upstreamnt  +downstreamnt
atgccacacgaagagctgccgtcgctgcagagaccccgctatggctctattgtggacgat
gaaaggctctctgcagaggagatggatgagaggaggcggcagaacattgcttatgaatat
ctgtgccacttagaggaagccaaaaggtggatggaagtttgcttagttgaagaattgcca
ccaaccactgaattggaagaagggctccggaatggagtttaccttgcaaagttagccaag
ttctttgccccgaaaatggtatcagagaaaaagatctatgatgtggaacaaacacgttat
aagaagtctggccttcattttcgacacacagataataccgtccagtggttaagagcgatg
gagtctattggtctacccaagatattttatccagaaacaacagatgtctatgatcggaaa
aacataccaagaatgatatattgcattcacgcactgagtttgtatctgttcaaactagga
atagcaccccagatccaggatttgttgggcaaagtagacttcacagaggaggaaatcagt
aatatgagaaaagaacttgagaaatatggaatacagatgccatctttcagcaaaataggt
ggtattctggccaatgaactgtccgtggatgaagctgcattacatgctgcagttatagcc
attaatgaagcagttgaaaaaggaatagcagagcaaaccgttgtaacactaagaaaccca
aatgcggttttaactttagtggatgacaaccttgcaccagaatatcagaaagaactctgg
gatgccaaaaagaaaaaagaggaaaatgcaagactgaagaatagctgtatttcagaagaa
gaaagagatgcttatgaagaactgctgacacaagcagaaatccaaggcaatattaataaa
gtcaacaggcaggctgcagtggaccatatcaatgctgtcattccggaaggtgaccccgag
aatacgctgcttgcactgaagaaaccagaggcccagctgcctgctgtttatccctttgct
gctgccatgtatcagaacgaacttttcaacctccagaaacagaacaccatgaactacttg
gcccacgaggagcttttgattgctgtggaaatgttgtctgctgttgctttactaaaccag
gccttggaaagcaacgatcttgtgtctgtgcagaatcaactcagaagccccgcaataggc
ttaaacaatctggacaaggcatatgtggaacgttatgcaaacacactactctctgttaaa
ctagaagttttatcccaagggcaagataacttaagctggaatgaaattcagaattgtatt
gatatggttaatgctcaaattcaagaagaaaatgaccgagttgtagctgtagggtacatc
aatgaagctattgatgaagggaatcctttgaggactttagaaactttgctcctacctact
gcgaatattagtgatgtggacccagcccatgcccagcactaccaggatgttttataccat
gctaaatcacagaaactcggagactctgagagtgtttccaaagtgctttggctggatgag
atacagcaagccgtcgatgatgccaacgtggacgaggacagagcaaaacaatgggttact
ctggtggttgatgttaatcagtgtttggaaggaaaaaaatcaagtgatattttgtctgta
ttgaagtcttccacttctaatgcaaatgacataatcccggagtgtgctgacaaatactat
gatgcccttgtgaaggcaaaagagctcaaatctgaaagagtgtctagtgacggttcatgg
ctcaaactcaacctgcacaaaaaatatgactactattacaacactgattcaaaagagagt
tcctgggtcacacctgaatcatgcttgtataaagaatcatggctcacaggaaaagaaatc
gaggacattattgaggaagtcacagtaggttacattcgtgagaatatatggtctgcttca
gaagagttgcttcttcgctttcaagccacaagctcaggacccatccttagggaagagttt
gaagctagaaaatcatttttgcatgaacaagaagagaatgtggtcaaaatacaggctttt
tggaaaggatataaacaacggaaggagtatatgcacaggcggcaaacgttcattgataat
actgattctattgtgaagattcagtcctggttccgaatggcaactgcaagaaagagctat
ctttcaagactacagtatttcagagatcataataatgaaattgtgaaaatacagtcactg
ttgagagcgaacaaagctagagatgactacaaaacattggttggctctgaaaacccacca
ttaacagtaattcgcaaatttgtatacctgctggaccaaagtgatttggatttccaggag
gaactagaggttgcacgattaagggaagaagtagtgaccaagatcagggccaatcaacag
ctggaaaaagacctgaacctgatggacatcaagattggactgctggtgaagaacaggatc
acactagaggatgtaatttcacacagtaaaaagctgaacaagaaaaaaggaggagaaatg
gaaatactgaataacaccgacaaccaaggaataaaaagtttgagtaaggagaggagaaaa
acactagaaacatatcagcagctgttttaccttttacagaccaaccctttatacttggct
aagctgattttccagatgccacagaacaagtccactaaatttatggatactgttattttc
acactatataattatgcctctaatcagcgagaagaatatctacttctcaagctttttaaa
actgctctggaggaagaaataaaatcaaaagtggaccaggtacaggacatagttactggt
aaccctacagtcatcaagatggtcgtcagcttcaatagaggtgcccggggacagaacacc
ctgcgccaactcctggctccagtggtaaaagagatcatcgacgacaagtcgctgattatc
aacacaaaccctgtagaggtgtacaaggcttgggtgaaccaactagaaacacagactgga
gaggccagcaagttgccttatgatgtgaccacagaacaagctctaacatacccagaagtg
aaaaataaactggaggcttccattgagaacctgagaagggtcaccgacaaagtcctgaat
tctatcatttcttcccttgatctactgccttatggattgaggtatatagccaaagtactg
aagaattcgatccatgagaaattccccgatgcaacagaagatgagctattaaagattgtt
ggaaacctcctgtactatcggtacatgaatccagccattgtagctccagatggctttgat
atcatcgacatgacagctggaggtcagataaattctgaccaaaggagaaacttaggatca
gtggccaaggttcttcagcacgcagcctccaacaagctgtttgaaggagaaaatgagcat
ctctcatctatgaacaattatttatcagagacgtatcaggaattcaggaaatatttcaaa
gaagcatgtaatgtccctgagccagaagagaagtttaatatggacaaatacacagacctg
gtgacagtcagcaaaccagtcatttatatttcaattgaagaaatcatcagcacacactca
ctcctgttggaacaccaggatgcaattgcccctgagaaaaatgacttactgagtgaattg
ctggggtcgctgggagaggtgccaaccgtggaatcttttcttggggaaggagcagttgac
cccaatgaccctaacaaggcaaatacactaagtcagctttcaaagaccgagatttctctt
gtcttgacaagcaaatatgacatagaggacggtgaagctatagatagccgaagcctcatg
ataaagaccaagaagctgataattgatgtgatccggaaccagccagggaacacattgaca
gaaatcttagagacaccagcaactgcgcaacaggaggtagaccatgccacggacatggtg
agccgtgcaatgatagattccaggactccagaagaaatgaagcatagccaatctatgatt
gaagatgcacagctgcctcttgagcagaagaagaggaaaatccagaggaatcttcggacg
ttggaacagactggacacgtgtcatccgaaaataaataccaagacattctcaatgagatt
gccaaggatattcgaaatcaaagaatctatcgtaagcttcgaaaagctgaattggcaaaa
cttcagcagaccctgaatgcacttaacaagaaggcagcattttatgaagagcaaatcaat
tattatgacacctacataaagacttgtttagacaacttaaaaagaaaaaatactcggaga
tcaattaaactagatggaaaaggagaacccaaaggggcgaagagagcgaagccagtgaag
tacactgcagcaaagctgcatgagaaaggtgtcctgctagatatagatgatcttcaaaca
aaccagtttaagaatgttacatttgatatcatagctactgaagatgtaggcattttcgat
gtaagatcaaaattccttggtgttgagatggaaaaggtgcaactcaatattcaggattta
cttcagatgcaatatgaaggagtagctgtaatgaaaatgtttgataaggttaaagtgaat
gtaaaccttctcatatacctgctgaacaagaagttctatggaaagtga

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