KEGG T01001: 11069

Homo sapiens (human): 11069

Entry

11069 CDS T01001

Gene name

RAPGEF4, CAMP-GEFII, CGEF2, EPAC2, Nbla00496

Definition

Rap guanine nucleotide exchange factor (GEF) 4

Orthology

K04351

Rap guanine nucleotide exchange factor (GEF) 4

Organism

hsa Homo sapiens (human)

Pathway

hsa04670	Leukocyte transendothelial migration
hsa04911	Insulin secretion

Class

Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:hsa04670]
Organismal Systems; Endocrine system; Insulin secretion [PATH:hsa04911]

SSDB

Motif

Pfam:

RasGEF DEP cNMP_binding RasGEF_N RA

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

2q31-q32

AA seq 867 aa
MLYKKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKIL
RAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQV
LLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGP
DAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVL
FNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCH
FLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGT
PEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQ
EKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLP
ELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTI
RVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACP
REQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRH
NFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFF
AIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFM
PLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVR
SYVRQLNVIDNQRTLSQMSHRLEPRRP

NT seq 2604 nt +upstreamnt +downstreamnt
atgctctacaagaaatatcgacagtatatggcaggacttctggctcctccttatggtgtt
atggaaacgggctctaacaatgacaggattcctgacaaggagaacacacctctcattgaa
cctcacgttcctcttcgtcctgctaacaccattaccaaggtcccttcagagaagatcctc
agagctggaaaaattttacgaaatgccattctctctcgagcacctcacatgataagagat
agaaaataccacctaaagacatacagacaatgctgtgtgggaactgaactggtggactgg
atgatgcagcagacaccatgtgttcactcccggactcaagctgttggcatgtggcaagtc
ctgttagaagatggtgttctcaaccacgtggaccaggagcaccatttccaagacaaatat
ttattctatcgatttctggatgatgagcacgaggatgcccctttgcctactgaggaggag
aagaaggagtgtgatgaggagctccaggacaccatgctgctgctgtcacagatgggcccc
gacgcccacatgaggatgatccttcgcaaaccacctggccagaggactgtggatgaccta
gagattatctatgaggagcttcttcatattaaagccttatcccatctttctaccacagtg
aaacgagagttagcaggtgttctcatttttgagtctcacgccaaaggagggactgtgttg
tttaaccagggggaagaaggtacctcctggtacattattctaaaaggatcagtgaatgta
gtcatttacggcaagggtgtggtctgcaccctgcatgaaggagatgacttcggcaagtta
gcactagtgaatgatgccccacgagctgcctctatcgtcttacgagaagataactgccat
ttcttaagagtagacaaggaggatttcaaccggatcctaagggacgtggaggcgaataca
gtcagacttaaagaacatgaccaagatgtcttggtgctggagaaggtcccagcagggaac
agagcttctaatcaaggaaactcacagcctcagcaaaagtatactgtgatgtcaggaaca
cctgaaaaaattttagagcattttctagaaacaatacgccttgaggcaactttaaatgaa
gcaacagattctgttttaaatgactttattatgatgcactgtgtttttatgccaaatacc
cagctttgcccggcactggtggcccactaccacgcacagccttcacaaggtacagaacag
gagaaaatggattatgccctcaacaataagaggcgagtcatccgcctggttctacagtgg
gctgccatgtatggagacctcctgcaagaggatgacgtgtctatggccttcctggaggag
ttttatgtatctgtatcagatgatgcccggatgattgctgccctcaaggagcaactgcca
gagttggagaagattgtcaagcaaatctcagaagatgcaaaggcaccacaaaagaagcac
aaggttcttttgcaacagttcaatacgggcgatgagagagcccagaagcgccagcctatc
cgcggctctgatgaagttctgtttaaggtctattgcatggaccacacctacacaaccatt
cgggtgccagtggccacttcggtgaaggaagtcatcagtgcagttgccgacaagctgggc
tccggggagggcctgatcatagtcaagatgagttccggaggagaaaaggtggtgctcaaa
cctaatgatgtttcagtatttacgacgctcaccattaatggacgcctgtttgcttgcccg
cgagagcaattcgattcactgactcccttaccagaacaggaaggcccaactgttggaaca
gtgggaacttttgaactgatgagctccaaagatttagcataccagatgacaatttatgat
tgggaactcttcaactgcgtgcatgagctggagctaatctatcacacatttggaaggcat
aattttaaaaagaccacagcaaacttggatttgttcctgaggagatttaatgaaattcag
ttttgggtcgtcactgagatctgcctttgttctcagctcagcaagcgtgttcagctatta
aaaaaatttattaagatagcagcccactgtaaggagtataaaaatctgaattcctttttt
gccatcgtcatgggactaagtaacgttgctgtgagccgcttggcactaacgtgggagaaa
ctgccaagcaagttcaagaagttctatgcggagtttgaaagtttaatggacccttcaagg
aaccacagggcctacaggctgacagtagctaagctggaacctcctctcatccccttcatg
cctttgctcattaaagatatgacatttactcatgaggggaacaagacgttcattgacaat
ctagtaaactttgaaaaaatgcgcatgattgcaaatacggccagaacagtgagatactac
aggagccaacccttcaatcctgatgcagctcaagctaataagaaccatcaggatgtccgg
agttatgtacggcaattaaatgtgattgacaaccagagaactttatcacagatgtcacac
agattagagcctcgtcgaccatag

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (20)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (56)   
   RefSeq(nuc) (2)   
   GenBank (27)   
   EMBL (27)   
Protein domain (5)   
   Pfam (5)   
All databases (96)   

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