KEGG   Homo sapiens (human): 11221Help
Entry
11221             CDS       T01001                                 

Gene name
DUSP10, MKP-5, MKP5
Definition
(RefSeq) dual specificity phosphatase 10
  KO
K20216  
dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    11221 (DUSP10)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     11221 (DUSP10)
    3.1.3.48  protein-tyrosine-phosphatase
     11221 (DUSP10)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    11221 (DUSP10)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q9Y6W6(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
1q41
AA seq 482 aa AA seqDB search
MPPSPLDDRVVVALSRPVRPQDLNLCLDSSYLGSANPGSNSHPPVIATTVVSLKAANLTY
MPSSSGSARSLNCGCSSASCCTVATYDKDNQAQTQAIAAGTTTTAIGTSTTCPANQMVNN
NENTGSLSPSSGVGSPVSGTPKQLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPF
MEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKEIIVYDENT
NEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQECREVGGGA
SAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPL
YHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVI
AYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVET
VV
NT seq 1449 nt NT seq  +upstreamnt  +downstreamnt
atgcctccgtctcctttagacgacagggtagtagtggcactatctaggcccgtccgacct
caggatctcaacctttgtttagactctagttaccttggctctgccaacccaggcagtaac
agccaccctcctgtcatcgccaccaccgttgtgtccctcaaggctgcgaatctgacgtat
atgccctcatccagcggctctgcccgctcgctgaattgtggatgcagcagtgccagctgc
tgcactgtggcaacctacgacaaggacaatcaggcccaaacccaagccattgccgctggc
accaccaccactgccatcggaacctctaccacctgccctgctaaccagatggtcaacaat
aatgagaatacaggctctctaagtccatcaagtggggtgggcagccctgtgtcagggacc
cccaagcagctagccagcatcaaaataatctaccccaatgacttggcaaagaagatgacc
aaatgcagcaagagtcacctgccgagtcagggccctgtcatcattgactgcaggcccttc
atggagtacaacaagagtcacatccaaggagctgtccacattaactgtgccgataagatc
agccggcggagactgcagcagggcaagatcactgtcctagacttgatttcctgtagggaa
ggcaaggactctttcaagaggatcttttccaaagaaattatagtttatgatgagaatacc
aatgaaccaagccgagtgatgccctcccagccacttcacatagtcctcgagtccctgaag
agagaaggcaaagaacctctggtgttgaaaggtggacttagtagttttaagcagaaccat
gaaaacctctgtgacaactccctccagctccaagagtgccgggaggtggggggcggcgca
tccgcggcctcgagcttgctacctcagcccatccccaccacccctgacatcgagaacgct
gagctcacccccatcttgcccttcctgttccttggcaatgagcaggatgctcaggacctg
gacaccatgcagcggctgaacatcggctacgtcatcaacgtcaccactcatcttcccctc
taccactatgagaaaggcctgttcaactacaagcggctgccagccactgacagcaacaag
cagaacctgcggcagtactttgaagaggcttttgagttcattgaggaagctcaccagtgt
gggaaggggcttctcatccactgccaggctggggtgtcccgctccgccaccatcgtcatc
gcttacttgatgaagcacactcggatgaccatgactgatgcttataaatttgtcaaaggc
aaacgaccaattatctccccaaaccttaacttcatggggcagttgctagagttcgaggaa
gacctaaacaacggtgtgacaccgagaatccttacaccaaagctgatgggcgtggagacg
gttgtgtga

KEGG   Homo sapiens (human): 1843Help
Entry
1843              CDS       T01001                                 

Gene name
DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10
Definition
(RefSeq) dual specificity phosphatase 1
  KO
K21278  
dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Serotonergic synapse
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1843 (DUSP1)
 Organismal Systems
  Nervous system
   04726 Serotonergic synapse
    1843 (DUSP1)
 Human Diseases
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    1843 (DUSP1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1843 (DUSP1)
    3.1.3.48  protein-tyrosine-phosphatase
     1843 (DUSP1)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1843 (DUSP1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P28562(Tchem)
UniProt: 
Position
5q35.1
AA seq 367 aa AA seqDB search
MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAM
GLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFF
LKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPF
LYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEA
IDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFS
FMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSP
ITTSPSC
NT seq 1104 nt NT seq  +upstreamnt  +downstreamnt
atggtcatggaagtgggcaccctggacgctggaggcctgcgggcgctgctgggggagcga
gcggcgcaatgcctgctgctggactgccgctccttcttcgctttcaacgccggccacatc
gccggctctgtcaacgtgcgcttcagcaccatcgtgcggcgccgggccaagggcgccatg
ggcctggagcacatcgtgcccaacgccgagctccgcggccgcctgctggccggcgcctac
cacgccgtggtgttgctggacgagcgcagcgccgccctggacggcgccaagcgcgacggc
accctggccctggcggccggcgcgctctgccgcgaggcgcgcgccgcgcaagtcttcttc
ctcaaaggaggatacgaagcgttttcggcttcctgcccggagctgtgcagcaaacagtcg
acccccatggggctcagccttcccctgagtactagcgtccctgacagcgcggaatctggg
tgcagttcctgcagtaccccactctacgatcagggtggcccggtggaaatcctgcccttt
ctgtacctgggcagtgcgtatcacgcttcccgcaaggacatgctggatgccttgggcatc
actgccttgatcaacgtctcagccaattgtcccaaccattttgagggtcactaccagtac
aagagcatccctgtggaggacaaccacaaggcagacatcagctcctggttcaacgaggcc
attgacttcatagactccatcaagaatgctggaggaagggtgtttgtccactgccaggca
ggcatttcccggtcagccaccatctgccttgcttaccttatgaggactaatcgagtcaag
ctggacgaggcctttgagtttgtgaagcagaggcgaagcatcatctctcccaacttcagc
ttcatgggccagctgctgcagtttgagtcccaggtgctggctccgcactgttcggcagag
gctgggagccccgccatggctgtgctcgaccgaggcacctccaccaccaccgtgttcaac
ttccccgtctccatccctgtccactccacgaacagtgcgctgagctaccttcagagcccc
attacgacctctcccagctgctga

KEGG   Homo sapiens (human): 1844Help
Entry
1844              CDS       T01001                                 

Gene name
DUSP2, PAC-1, PAC1
Definition
(RefSeq) dual specificity phosphatase 2
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1844 (DUSP2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1844 (DUSP2)
    3.1.3.48  protein-tyrosine-phosphatase
     1844 (DUSP2)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1844 (DUSP2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
Pharos: 
Q05923(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
2q11.2
AA seq 314 aa AA seqDB search
MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRAR
GPPAAVLACLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRA
GPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYL
FLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAI
GFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSF
MGQLLQFETQVLCH
NT seq 945 nt NT seq  +upstreamnt  +downstreamnt
atggggctggaggcggcgcgcgagctggagtgcgcggcgctgggcacgctgctgcgggat
ccgcgggaggcggaacgcacgctgctgctggactgccgccccttcctggccttctgccgg
cgccacgtgcgcgccgcgcggccagtgccttggaacgcgctgctgcggcgccgcgcgcgc
ggccctcctgccgccgttctcgcctgcctgctgcccgaccgcgcgctgcggacgcgcctg
gtccgcggggagctggcgcgggccgtggtgctggacgagggcagtgcctcggtggcggag
ctccggcccgacagcccggctcatgtgctgctggccgcgctgctgcacgagacccgcgcg
gggcccactgccgtgtacttcctgcgaggaggcttcgacggcttccagggctgctgtccc
gatctgtgctctgaggcccccgcccctgcgctgccgccaacaggggacaaaaccagccgc
tccgactccagggctcctgtctacgaccagggtggccctgtggagatcttgccctacctg
ttcctgggcagctgcagtcactcgtcagacctgcaggggctgcaggcctgtggcatcaca
gccgtcctcaacgtgtccgccagctgccccaaccactttgagggccttttccgctacaag
agtatccctgtggaggacaaccagatggtggagatcagtgcctggttccaggaggccata
ggcttcattgactgggtgaagaacagcggaggccgggtgctggtgcactgccaggcgggt
atctcgcgctctgccaccatctgtctggcatacctcatgcagagtcgccgtgtgcggctg
gacgaggcctttgacttcgttaagcagcgccggggggtcatctcccccaacttcagtttc
atggggcagctgctgcagtttgagacccaggtgctgtgtcactga

KEGG   Homo sapiens (human): 1846Help
Entry
1846              CDS       T01001                                 

Gene name
DUSP4, HVH2, MKP-2, MKP2, TYP
Definition
(RefSeq) dual specificity phosphatase 4
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1846 (DUSP4)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1846 (DUSP4)
    3.1.3.48  protein-tyrosine-phosphatase
     1846 (DUSP4)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1846 (DUSP4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
Pharos: 
Q13115(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
8p12
AA seq 394 aa AA seqDB search
MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGY
ILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLRE
DSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLD
LGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY
QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR
VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATP
TSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC
NT seq 1185 nt NT seq  +upstreamnt  +downstreamnt
atggtgacgatggaggagctgcgggagatggactgcagtgtgctcaaaaggctgatgaac
cgggacgagaatggcggcggcgcgggcggcagcggcagccacggcaccctggggctgccg
agcggcggcaagtgcctgctgctggactgcagaccgttcctggcgcacagcgcgggctac
atcctaggttcggtcaacgtgcgctgtaacaccatcgtgcggcggcgggctaagggctcc
gtgagcctggagcagatcctgcccgccgaggaggaggtacgcgcccgcttgcgctccggc
ctctactcggcggtcatcgtctacgacgagcgcagcccgcgcgccgagagcctccgcgag
gacagcaccgtgtcgctggtggtgcaggcgctgcgccgcaacgccgagcgcaccgacatc
tgcctgctcaaaggcggctatgagaggttttcctccgagtacccagaattctgttctaaa
accaaggccctggcagccatcccacccccggttccccccagtgccacagagcccttggac
ctgggctgcagctcctgtgggaccccactacacgaccaggggggtcctgtggagatcctt
cccttcctctacctcggcagtgcctaccatgctgcccggagagacatgctggacgccctg
ggcatcacggctctgttgaatgtctcctcggactgcccaaaccactttgaaggacactat
cagtacaagtgcatcccagtggaagataaccacaaggccgacatcagctcctggttcatg
gaagccatagagtacatcgatgccgtgaaggactgccgtgggcgcgtgctggtgcactgc
caggcgggcatctcgcggtcggccaccatctgcctggcctacctgatgatgaagaaacgg
gtgaggctggaggaggccttcgagttcgttaagcagcgccgcagcatcatctcgcccaac
ttcagcttcatggggcagctgctgcagttcgagtcccaggtgctggccacgtcctgtgct
gcggaggctgctagcccctcgggacccctgcgggagcggggcaagacccccgccaccccc
acctcgcagttcgtcttcagctttccggtctccgtgggcgtgcactcggcccccagcagc
ctgccctacctgcacagccccatcaccacctctcccagctgttag

KEGG   Homo sapiens (human): 1847Help
Entry
1847              CDS       T01001                                 

Gene name
DUSP5, DUSP, HVH3
Definition
(RefSeq) dual specificity phosphatase 5
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1847 (DUSP5)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1847 (DUSP5)
    3.1.3.48  protein-tyrosine-phosphatase
     1847 (DUSP5)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1847 (DUSP5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q16690(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
10q25.2
AA seq 384 aa AA seqDB search
MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAV
SARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGP
RVYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPV
EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISS
HFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMV
SPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASV
LAPVPTHSTVSELSRSPVATATSC
NT seq 1155 nt NT seq  +upstreamnt  +downstreamnt
atgaaggtcacgtcgctcgacgggcgccagctgcgcaagatgctccgcaaggaggcggcg
gcgcgctgcgtggtgctcgactgccggccctatctggccttcgctgcctcgaacgtgcgc
ggctcgctcaacgtcaacctcaactcggtggtgctgcggcgggcccggggcggcgcggtg
tcggcgcgctacgtgctgcccgacgaggcggcgcgcgcgcggctcctgcaggagggcggc
ggcggcgtcgcggccgtggtggtgctggaccagggcagccgccactggcagaagctgcga
gaggagagcgccgcgcgtgtcgtcctcacctcgctactcgcttgcctacccgccggcccg
cgggtctacttcctcaaagggggatatgagactttctactcggaatatcctgagtgttgc
gtggatgtaaaacccatttcacaagagaagattgagagtgagagagccctcatcagccag
tgtggaaaaccagtggtaaatgtcagctacaggccagcttatgaccagggtggcccagtt
gaaatccttcccttcctctaccttggaagtgcctaccatgcatccaagtgcgagttcctc
gccaacctgcacatcacagccctgctgaatgtctcccgacggacctccgaggcctgcgcg
acccacctacactacaaatggatccctgtggaagacagccacacggctgacattagctcc
cactttcaagaagcaatagacttcattgactgtgtcagggaaaagggaggcaaggtcctg
gtccactgtgaggctgggatctcccgttcacccaccatctgcatggcttaccttatgaag
accaagcagttccgcctgaaggaggccttcgattacatcaagcagaggaggagcatggtc
tcgcccaactttggcttcatgggccagctcctgcagtacgaatctgagatcctgccctcc
acgcccaacccccagcctccctcctgccaaggggaggcagcaggctcttcactgataggc
catttgcagacactgagccctgacatgcagggtgcctactgcacattccctgcctcggtg
ctggcaccggtgcctacccactcaacagtctcagagctcagcagaagccctgtggcaacg
gccacatcctgctaa

KEGG   Homo sapiens (human): 1848Help
Entry
1848              CDS       T01001                                 

Gene name
DUSP6, HH19, MKP3, PYST1
Definition
(RefSeq) dual specificity phosphatase 6
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Transcriptional misregulation in cancer
Disease
H00255  
Hypogonadotropic hypogonadism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1848 (DUSP6)
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    1848 (DUSP6)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1848 (DUSP6)
    3.1.3.48  protein-tyrosine-phosphatase
     1848 (DUSP6)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1848 (DUSP6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q16828(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
12q21.33
AA seq 381 aa AA seqDB search
MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTTPSNQNVYQVDSLQST
NT seq 1146 nt NT seq  +upstreamnt  +downstreamnt
atgatagatacgctcagacccgtgcccttcgcgtcggaaatggcgatcagcaagacggtg
gcgtggctcaacgagcagctggagctgggcaacgagcggctgctgctgatggactgccgg
ccgcaggagctatacgagtcgtcgcacatcgagtcggccatcaacgtggccatcccgggc
atcatgctgcggcgcctgcagaagggtaacctgccggtgcgcgcgctcttcacgcgcggc
gaggaccgggaccgcttcacccggcgctgtggcaccgacacagtggtgctctacgacgag
agcagcagcgactggaacgagaatacgggcggcgagtcggtgctcgggctgctgctcaag
aagctcaaggacgagggctgccgggcgttctacctggaaggtggcttcagtaagttccaa
gccgagttctccctgcattgcgagaccaatctagacggctcgtgtagcagcagctcgccg
ccgttgccagtgctggggctcgggggcctgcggatcagctctgactcttcctcggacatc
gagtctgaccttgaccgagaccccaatagtgcaacagactcggatggtagtccgctgtcc
aacagccagccttccttcccagtggagatcttgcccttcctctacttgggctgtgccaaa
gactccaccaacttggacgtgttggaggaattcggcatcaagtacatcttgaacgtcacc
cccaatttgccgaatctctttgagaacgcaggagagtttaaatacaagcaaatccccatc
tcggatcactggagccaaaacctgtcccagtttttccctgaggccatttctttcatagat
gaagcccggggcaagaactgtggtgtcttggtacattgcttggctggcattagccgctca
gtcactgtgactgtggcttaccttatgcagaagctcaatctgtcgatgaacgatgcctat
gacattgtcaaaatgaaaaaatccaacatatcccctaacttcaacttcatgggtcagctg
ctggacttcgagaggacgctgggactcagcagcccatgtgacaacagggttccagcacag
cagctgtattttaccaccccttccaaccagaatgtataccaggtggactctctgcaatct
acgtga

KEGG   Homo sapiens (human): 1849Help
Entry
1849              CDS       T01001                                 

Gene name
DUSP7, MKPX, PYST2
Definition
(RefSeq) dual specificity phosphatase 7
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1849 (DUSP7)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1849 (DUSP7)
    3.1.3.48  protein-tyrosine-phosphatase
     1849 (DUSP7)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1849 (DUSP7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q16829(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
3p21.2
AA seq 419 aa AA seqDB search
MKNQLRGPPARAHMSTSGAAAAGGTRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWL
QEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHAD
KERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQT
EYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSS
QPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISD
HWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDF
VKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
NT seq 1260 nt NT seq  +upstreamnt  +downstreamnt
atgaaaaaccagctccgcggccccccagcgcgggcgcacatgtcgacttcgggggcggcg
gcggctgggggcacccgggcggggtccgagcccggtgcggggtcggggtccggcgcaggc
accggggcgggcgcggcgacgggggcaggggccatgccctgcaagagcgccgagtggctg
caggaggagctggaggcgcgcggcggcgcgtccttgctgctgctcgactgccggccgcac
gagctcttcgagtcgtcgcacatcgagacggccatcaacctggccatcccgggcctcatg
ttgcgccgcctgcgcaagggcaacctgcccatccgctccatcatccccaaccacgccgac
aaggagcgcttcgccacgcgctgcaaggcggccaccgtgctgctctacgacgaggccacg
gccgagtggcagcccgagcccggcgctcccgcctccgtgctcggcctgctcctacagaag
ctgcgcgacgacggctgccaggcctactacctccaaggtggtttcaacaagtttcaaaca
gagtactctgagcactgcgagaccaacgtggacagctcttcctcgccgagcagctcgcca
cccacctcagtgctgggcctggggggcctgcgcatcagctctgactgctccgacggcgag
tcggaccgagagctgcccagcagtgccaccgagtcagacggcagccctgtgccatccagc
caaccagccttccctgtccagatcctgccctacctctacctcggctgcgccaaggactcc
accaacctggacgtgctcggcaagtatggcatcaagtatatcctcaatgtcacacccaac
ctacccaacgccttcgagcacggcggcgagttcacctacaagcagatccccatctctgac
cactggagccagaacctctcccagttcttccctgaggccatcagcttcattgacgaagcc
cgctccaagaagtgtggtgtcctggtgcactgcctggcaggcatcagccgctcagtgacg
gtcactgtggcctatctgatgcagaagatgaacctgtcactcaacgacgcctacgacttt
gtcaagaggaaaaagtccaacatctcgcccaacttcaacttcatggggcagctgctggac
tttgagcggacgctggggctaagcagcccgtgcgacaaccacgcgtcgagtgagcagctc
tacttttccacgcccaccaaccacaacctgttcccactcaatacgctggagtccacgtga

KEGG   Homo sapiens (human): 1850Help
Entry
1850              CDS       T01001                                 

Gene name
DUSP8, C11orf81, HB5, HVH-5, HVH8
Definition
(RefSeq) dual specificity phosphatase 8
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1850 (DUSP8)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1850 (DUSP8)
    3.1.3.48  protein-tyrosine-phosphatase
     1850 (DUSP8)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1850 (DUSP8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q13202(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
11p15.5
AA seq 625 aa AA seqDB search
MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQ
QGKVTIAELIQPAARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVA
ILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKD
LMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSC
QVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL
KLLAALQGDPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGGLSAGGEPPA
PPTPPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDGPGPPDPGEAP
KLCKLDSPSGAALGLSSPSPDSPDAAPEARPRPRRRPRPPAGSPARSPAHSLGLNFGDAA
RQTPRHGLSALSAPGLPGPGQPAGPGAWAPPLDSPGTPSPDGPWCFSPEGAQGAGGVLFA
PFGRAGAPGPGGGSDLRRREAARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEGMVEGR
ARGEELAALGKQASFSGSVEVIEVS
NT seq 1878 nt NT seq  +upstreamnt  +downstreamnt
atggctggggaccggctcccgaggaaggtgatggatgccaagaagctggccagcctgctg
cggggcgggcctggggggccgctggtcatcgacagccgctccttcgtggagtacaacagc
tggcatgtgctcagctccgtcaacatctgctgctccaagctggtgaagcggcggctgcag
cagggcaaggtgaccattgcggagctcatccagccggctgcacgcagccaggtggaggct
acggagccacaggacgtggtggtctatgaccagagcacgcgggacgccagcgtgctggcc
gcagacagcttcctctccatcctgctgagcaagctggacggctgcttcgacagcgtggcc
atcctcactgggggcttcgccaccttctcctcctgcttccccggcctctgcgagggcaag
cctgctgccctgctacccatgagcctctcccagccctgcctgcctgtgcccagcgtgggc
ctgacccgcatcctgcctcacctctacctgggctcgcagaaggacgtcctaaacaaggat
ctgatgacgcaaaatggaataagctacgtcctcaacgccagcaactcctgccccaagcct
gacttcatctgcgagagccgcttcatgcgggtccccatcaacgacaactactgtgaaaaa
ctgctgccctggctggacaagtccatcgagttcatcgataaagccaagctctccagctgc
caagtcatcgtccactgtctggctggcatctcccgctctgccaccatcgccatcgcctac
atcatgaagaccatgggcatgtcctccgacgacgcctacaggttcgtgaaggacaggcgc
ccgtccatctcgcccaacttcaacttcctgggccagctgctggagtacgagcgcagcctg
aagctgctggccgccctgcagggcgacccgggcaccccctcagggacgccggagcctccg
cccagtcctgccgccggggccccgctgccacggctgccaccacctacctcagagagcgct
gccacagggaatgcggctgccagggagggcggcctgagcgcgggcggggagccccccgcg
ccccccacgcccccggcgaccagcgcactgcagcagggcctgcgcggcctgcacctctcc
tcggaccgcctgcaggacactaaccgcctcaagcgctccttctccctggacatcaagtct
gcctacgcccctagcaggcggcccgacggccccgggccccccgaccccggcgaggccccg
aagctctgcaagctggacagcccgtcgggggccgcgctgggcctgtcctcgcccagcccg
gacagcccggacgccgcgcctgaggcgcgcccacggccccgccggcggccccggcccccc
gccggctcccccgcgcgctcccccgcgcacagcctcggcctgaacttcggcgatgcggcc
cggcagactccgcggcacggcctctcggccctgtcggcgcccgggctgcccggccctggc
cagccggccggccccggggcctgggcaccgccgctcgactccccaggcacgccgtcgccc
gacgggccctggtgcttcagccccgagggcgcacagggggcgggcggggtgctgtttgcg
cccttcggccgggcgggcgccccgggaccaggcggcggcagcgacctgcggcggcgggag
gcagcgagggctgagccccgggacgcgcggaccggctggcccgaggagccggccccggag
acgcagttcaagcgccgcagctgccagatggagttcgaggagggcatggtggaggggcgc
gcgcgcggcgaggagctggccgccctgggcaagcaggcgagcttctcgggcagcgtggag
gtcatcgaggtgtcctga

KEGG   Homo sapiens (human): 1852Help
Entry
1852              CDS       T01001                                 

Gene name
DUSP9, MKP-4, MKP4
Definition
(RefSeq) dual specificity phosphatase 9
  KO
K18498  
dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1852 (DUSP9)
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    1852 (DUSP9)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1852 (DUSP9)
    3.1.3.48  protein-tyrosine-phosphatase
     1852 (DUSP9)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1852 (DUSP9)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q99956(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
Xq28
AA seq 384 aa AA seqDB search
MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLS
VRALLPGPPLQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLA
YYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADR
DSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNL
PNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTV
TVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQA
SAASNPPSFFTTPTSDGAFELAPT
NT seq 1155 nt NT seq  +upstreamnt  +downstreamnt
atggagggtctgggccgctcgtgcctgtggctgcgtcgggagctgtcgcccccgcggccg
cggctcctgctcctggactgccgcagccgcgagctgtacgagtcggcgcgcatcggtggg
gcgctgagcgtggccctgccggcgctcctgctgcgccgcctgcggaggggcagcctgtcg
gtgcgcgcgctcctgcctgggccgccgctgcagccgcccccgcctgcccccgtgctcctg
tacgaccagggcgggggccggcgccggcgcggggaggccgaggccgaggccgaggagtgg
gaggccgagtcggtgctgggcaccctgctgcagaagctgcgagaggaaggctacctggcc
tactacctccagggaggcttcagcagattccaggccgagtgccctcacctgtgtgagacc
agccttgctggccgtgccggctccagcatggcgccggtgcccggtccagtgcccgtggtg
gggttgggcagcctgtgcctgggctccgactgctctgatgcggaatccgaggctgaccgc
gactccatgagctgtggcctggattcggagggtgccacacccccaccagtggggctgcgg
gcatccttccctgtccagatcctgcccaacctctatctgggcagtgcccgggattccgcc
aatttggagagcctggccaaactgggcatccgctacatcctcaatgtcacccccaacctc
ccaaacttcttcgagaagaatggtgactttcactacaagcagatccccatctccgaccac
tggagccagaacctgtcgcggttctttccggaggccattgagttcattgatgaggccttg
tcccagaactgcggggtgctcgtccactgcttggcgggggtcagccgttctgtcaccgtc
actgtggcctacctcatgcagaagctccacctctctctcaacgatgcctatgacctggtc
aagaggaagaagtctaacatctcccccaacttcaacttcatggggcagttgctggacttt
gagcgcagcttgcggctggaggagcgccactcgcaggagcagggcagtggggggcaggca
tctgcggcctccaacccgccctccttcttcaccacccccaccagtgatggcgccttcgag
ctggcccccacctag

KEGG   Homo sapiens (human): 80824Help
Entry
80824             CDS       T01001                                 

Gene name
DUSP16, MKP-7, MKP7
Definition
(RefSeq) dual specificity phosphatase 16
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    80824 (DUSP16)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     80824 (DUSP16)
    3.1.3.48  protein-tyrosine-phosphatase
     80824 (DUSP16)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    80824 (DUSP16)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Pharos: 
Q9BY84(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
12p13.2
AA seq 665 aa AA seqDB search
MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ
DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL
LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM
QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV
LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN
QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV
PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF
SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ
SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH
SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR
QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME
IIEVS
NT seq 1998 nt NT seq  +upstreamnt  +downstreamnt
atggcccatgagatgattggaactcaaattgttactgagaggttggtggctctgctggaa
agtggaacggaaaaagtgctgctaattgatagccggccatttgtggaatacaatacatcc
cacattttggaagccattaatatcaactgctccaagcttatgaagcgaaggttgcaacag
gacaaagtgttaattacagagctcatccagcattcagcgaaacataaggttgacattgat
tgcagtcagaaggttgtagtttacgatcaaagctcccaagatgttgcctctctctcttca
gactgttttctcactgtacttctgggtaaactggagaagagcttcaactctgttcacctg
cttgcaggtgggtttgctgagttctctcgttgtttccctggcctctgtgaaggaaaatcc
actctagtccctacctgcatttctcagccttgcttacctgttgccaacattgggccaacc
cgaattcttcccaatctttatcttggctgccagcgagatgtcctcaacaaggagctgatg
cagcagaatgggattggttatgtgttaaatgccagcaatacctgtccaaagcctgacttt
atccccgagtctcatttcctgcgtgtgcctgtgaatgacagcttttgtgagaaaattttg
ccgtggttggacaaatcagtagatttcattgagaaagcaaaagcctccaatggatgtgtt
ctagtgcactgtttagctgggatctcccgctccgccaccatcgctatcgcctacatcatg
aagaggatggacatgtctttagatgaagcttacagatttgtgaaagaaaaaagacctact
atatctccaaacttcaattttctgggccaactcctggactatgagaagaagattaagaac
cagactggagcatcagggccaaagagcaaactcaagctgctgcacctggagaagccaaat
gaacctgtccctgctgtctcagagggtggacagaaaagcgagacgcccctcagtccaccc
tgtgccgactctgctacctcagaggcagcaggacaaaggcccgtgcatcccgccagcgtg
cccagcgtgcccagcgtgcagccgtcgctgttagaggacagcccgctggtacaggcgctc
agtgggctgcacctgtccgcagacaggctggaagacagcaataagctcaagcgttccttc
tctctggatatcaaatcagtttcatattcagccagcatggcagcatccttacatggcttc
tcctcatcagaagatgctttggaatactacaaaccttccactactctggatgggaccaac
aagctatgccagttctcccctgttcaggaactatcggagcagactcccgaaaccagtcct
gataaggaggaagccagcatccccaagaagctgcagaccgccaggccttcagacagccag
agcaagcgattgcattcggtcagaaccagcagcagtggcaccgcccagaggtccctttta
tctccactgcatcgaagtgggagcgtggaggacaattaccacaccagcttccttttcggc
ctttccaccagccagcagcacctcacgaagtctgctggcctgggccttaagggctggcac
tcggatatcttggccccccagacctctaccccttccctgaccagcagctggtattttgcc
acagagtcctcacacttctactctgcctcagccatctacggaggcagtgccagttactct
gcctacagctgcagccagctgcccacttgcggagaccaagtctattctgtgcgcaggcgg
cagaagccaagtgacagagctgactcgcggcggagctggcatgaagagagcccctttgaa
aagcagtttaaacgcagaagctgccaaatggaatttggagagagcatcatgtcagagaac
aggtcacgggaagagctggggaaagtgggcagtcagtctagcttttcgggcagcatggaa
atcattgaggtctcctga

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