KEGG   Homo sapiens (human): 11221Help
Entry
11221             CDS       T01001                                 

Gene name
DUSP10, MKP-5, MKP5
Definition
(RefSeq) dual specificity phosphatase 10
  KO
K20216  
dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    11221 (DUSP10)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     11221 (DUSP10)
    3.1.3.48  protein-tyrosine-phosphatase
     11221 (DUSP10)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    11221 (DUSP10)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
Pharos: 
Q9Y6W6(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
1q41
AA seq 482 aa AA seqDB search
MPPSPLDDRVVVALSRPVRPQDLNLCLDSSYLGSANPGSNSHPPVIATTVVSLKAANLTY
MPSSSGSARSLNCGCSSASCCTVATYDKDNQAQTQAIAAGTTTTAIGTSTTCPANQMVNN
NENTGSLSPSSGVGSPVSGTPKQLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPF
MEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKEIIVYDENT
NEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQECREVGGGA
SAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPL
YHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVI
AYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVET
VV
NT seq 1449 nt NT seq  +upstreamnt  +downstreamnt
atgcctccgtctcctttagacgacagggtagtagtggcactatctaggcccgtccgacct
caggatctcaacctttgtttagactctagttaccttggctctgccaacccaggcagtaac
agccaccctcctgtcatcgccaccaccgttgtgtccctcaaggctgcgaatctgacgtat
atgccctcatccagcggctctgcccgctcgctgaattgtggatgcagcagtgccagctgc
tgcactgtggcaacctacgacaaggacaatcaggcccaaacccaagccattgccgctggc
accaccaccactgccatcggaacctctaccacctgccctgctaaccagatggtcaacaat
aatgagaatacaggctctctaagtccatcaagtggggtgggcagccctgtgtcagggacc
cccaagcagctagccagcatcaaaataatctaccccaatgacttggcaaagaagatgacc
aaatgcagcaagagtcacctgccgagtcagggccctgtcatcattgactgcaggcccttc
atggagtacaacaagagtcacatccaaggagctgtccacattaactgtgccgataagatc
agccggcggagactgcagcagggcaagatcactgtcctagacttgatttcctgtagggaa
ggcaaggactctttcaagaggatcttttccaaagaaattatagtttatgatgagaatacc
aatgaaccaagccgagtgatgccctcccagccacttcacatagtcctcgagtccctgaag
agagaaggcaaagaacctctggtgttgaaaggtggacttagtagttttaagcagaaccat
gaaaacctctgtgacaactccctccagctccaagagtgccgggaggtggggggcggcgca
tccgcggcctcgagcttgctacctcagcccatccccaccacccctgacatcgagaacgct
gagctcacccccatcttgcccttcctgttccttggcaatgagcaggatgctcaggacctg
gacaccatgcagcggctgaacatcggctacgtcatcaacgtcaccactcatcttcccctc
taccactatgagaaaggcctgttcaactacaagcggctgccagccactgacagcaacaag
cagaacctgcggcagtactttgaagaggcttttgagttcattgaggaagctcaccagtgt
gggaaggggcttctcatccactgccaggctggggtgtcccgctccgccaccatcgtcatc
gcttacttgatgaagcacactcggatgaccatgactgatgcttataaatttgtcaaaggc
aaacgaccaattatctccccaaaccttaacttcatggggcagttgctagagttcgaggaa
gacctaaacaacggtgtgacaccgagaatccttacaccaaagctgatgggcgtggagacg
gttgtgtga

KEGG   Homo sapiens (human): 1844Help
Entry
1844              CDS       T01001                                 

Gene name
DUSP2, PAC-1, PAC1
Definition
(RefSeq) dual specificity phosphatase 2
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1844 (DUSP2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1844 (DUSP2)
    3.1.3.48  protein-tyrosine-phosphatase
     1844 (DUSP2)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1844 (DUSP2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
Pharos: 
Q05923(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
2q11.2
AA seq 314 aa AA seqDB search
MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRAR
GPPAAVLACLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRA
GPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYL
FLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAI
GFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSF
MGQLLQFETQVLCH
NT seq 945 nt NT seq  +upstreamnt  +downstreamnt
atggggctggaggcggcgcgcgagctggagtgcgcggcgctgggcacgctgctgcgggat
ccgcgggaggcggaacgcacgctgctgctggactgccgccccttcctggccttctgccgg
cgccacgtgcgcgccgcgcggccagtgccttggaacgcgctgctgcggcgccgcgcgcgc
ggccctcctgccgccgttctcgcctgcctgctgcccgaccgcgcgctgcggacgcgcctg
gtccgcggggagctggcgcgggccgtggtgctggacgagggcagtgcctcggtggcggag
ctccggcccgacagcccggctcatgtgctgctggccgcgctgctgcacgagacccgcgcg
gggcccactgccgtgtacttcctgcgaggaggcttcgacggcttccagggctgctgtccc
gatctgtgctctgaggcccccgcccctgcgctgccgccaacaggggacaaaaccagccgc
tccgactccagggctcctgtctacgaccagggtggccctgtggagatcttgccctacctg
ttcctgggcagctgcagtcactcgtcagacctgcaggggctgcaggcctgtggcatcaca
gccgtcctcaacgtgtccgccagctgccccaaccactttgagggccttttccgctacaag
agtatccctgtggaggacaaccagatggtggagatcagtgcctggttccaggaggccata
ggcttcattgactgggtgaagaacagcggaggccgggtgctggtgcactgccaggcgggt
atctcgcgctctgccaccatctgtctggcatacctcatgcagagtcgccgtgtgcggctg
gacgaggcctttgacttcgttaagcagcgccggggggtcatctcccccaacttcagtttc
atggggcagctgctgcagtttgagacccaggtgctgtgtcactga

KEGG   Homo sapiens (human): 1846Help
Entry
1846              CDS       T01001                                 

Gene name
DUSP4, HVH2, MKP-2, MKP2, TYP
Definition
(RefSeq) dual specificity phosphatase 4
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1846 (DUSP4)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1846 (DUSP4)
    3.1.3.48  protein-tyrosine-phosphatase
     1846 (DUSP4)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1846 (DUSP4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
Pharos: 
Q13115(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
8p12
AA seq 394 aa AA seqDB search
MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGY
ILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLRE
DSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLD
LGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY
QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR
VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATP
TSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC
NT seq 1185 nt NT seq  +upstreamnt  +downstreamnt
atggtgacgatggaggagctgcgggagatggactgcagtgtgctcaaaaggctgatgaac
cgggacgagaatggcggcggcgcgggcggcagcggcagccacggcaccctggggctgccg
agcggcggcaagtgcctgctgctggactgcagaccgttcctggcgcacagcgcgggctac
atcctaggttcggtcaacgtgcgctgtaacaccatcgtgcggcggcgggctaagggctcc
gtgagcctggagcagatcctgcccgccgaggaggaggtacgcgcccgcttgcgctccggc
ctctactcggcggtcatcgtctacgacgagcgcagcccgcgcgccgagagcctccgcgag
gacagcaccgtgtcgctggtggtgcaggcgctgcgccgcaacgccgagcgcaccgacatc
tgcctgctcaaaggcggctatgagaggttttcctccgagtacccagaattctgttctaaa
accaaggccctggcagccatcccacccccggttccccccagtgccacagagcccttggac
ctgggctgcagctcctgtgggaccccactacacgaccaggggggtcctgtggagatcctt
cccttcctctacctcggcagtgcctaccatgctgcccggagagacatgctggacgccctg
ggcatcacggctctgttgaatgtctcctcggactgcccaaaccactttgaaggacactat
cagtacaagtgcatcccagtggaagataaccacaaggccgacatcagctcctggttcatg
gaagccatagagtacatcgatgccgtgaaggactgccgtgggcgcgtgctggtgcactgc
caggcgggcatctcgcggtcggccaccatctgcctggcctacctgatgatgaagaaacgg
gtgaggctggaggaggccttcgagttcgttaagcagcgccgcagcatcatctcgcccaac
ttcagcttcatggggcagctgctgcagttcgagtcccaggtgctggccacgtcctgtgct
gcggaggctgctagcccctcgggacccctgcgggagcggggcaagacccccgccaccccc
acctcgcagttcgtcttcagctttccggtctccgtgggcgtgcactcggcccccagcagc
ctgccctacctgcacagccccatcaccacctctcccagctgttag

KEGG   Homo sapiens (human): 1847Help
Entry
1847              CDS       T01001                                 

Gene name
DUSP5, DUSP, HVH3
Definition
(RefSeq) dual specificity phosphatase 5
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1847 (DUSP5)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1847 (DUSP5)
    3.1.3.48  protein-tyrosine-phosphatase
     1847 (DUSP5)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1847 (DUSP5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q16690(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
10q25.2
AA seq 384 aa AA seqDB search
MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAV
SARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGP
RVYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPV
EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISS
HFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMV
SPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASV
LAPVPTHSTVSELSRSPVATATSC
NT seq 1155 nt NT seq  +upstreamnt  +downstreamnt
atgaaggtcacgtcgctcgacgggcgccagctgcgcaagatgctccgcaaggaggcggcg
gcgcgctgcgtggtgctcgactgccggccctatctggccttcgctgcctcgaacgtgcgc
ggctcgctcaacgtcaacctcaactcggtggtgctgcggcgggcccggggcggcgcggtg
tcggcgcgctacgtgctgcccgacgaggcggcgcgcgcgcggctcctgcaggagggcggc
ggcggcgtcgcggccgtggtggtgctggaccagggcagccgccactggcagaagctgcga
gaggagagcgccgcgcgtgtcgtcctcacctcgctactcgcttgcctacccgccggcccg
cgggtctacttcctcaaagggggatatgagactttctactcggaatatcctgagtgttgc
gtggatgtaaaacccatttcacaagagaagattgagagtgagagagccctcatcagccag
tgtggaaaaccagtggtaaatgtcagctacaggccagcttatgaccagggtggcccagtt
gaaatccttcccttcctctaccttggaagtgcctaccatgcatccaagtgcgagttcctc
gccaacctgcacatcacagccctgctgaatgtctcccgacggacctccgaggcctgcgcg
acccacctacactacaaatggatccctgtggaagacagccacacggctgacattagctcc
cactttcaagaagcaatagacttcattgactgtgtcagggaaaagggaggcaaggtcctg
gtccactgtgaggctgggatctcccgttcacccaccatctgcatggcttaccttatgaag
accaagcagttccgcctgaaggaggccttcgattacatcaagcagaggaggagcatggtc
tcgcccaactttggcttcatgggccagctcctgcagtacgaatctgagatcctgccctcc
acgcccaacccccagcctccctcctgccaaggggaggcagcaggctcttcactgataggc
catttgcagacactgagccctgacatgcagggtgcctactgcacattccctgcctcggtg
ctggcaccggtgcctacccactcaacagtctcagagctcagcagaagccctgtggcaacg
gccacatcctgctaa

KEGG   Homo sapiens (human): 1848Help
Entry
1848              CDS       T01001                                 

Gene name
DUSP6, HH19, MKP3, PYST1
Definition
(RefSeq) dual specificity phosphatase 6
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Transcriptional misregulation in cancer
Disease
H00255  
Hypogonadotropic hypogonadism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1848 (DUSP6)
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    1848 (DUSP6)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1848 (DUSP6)
    3.1.3.48  protein-tyrosine-phosphatase
     1848 (DUSP6)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1848 (DUSP6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q16828(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
12q21.33
AA seq 381 aa AA seqDB search
MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTTPSNQNVYQVDSLQST
NT seq 1146 nt NT seq  +upstreamnt  +downstreamnt
atgatagatacgctcagacccgtgcccttcgcgtcggaaatggcgatcagcaagacggtg
gcgtggctcaacgagcagctggagctgggcaacgagcggctgctgctgatggactgccgg
ccgcaggagctatacgagtcgtcgcacatcgagtcggccatcaacgtggccatcccgggc
atcatgctgcggcgcctgcagaagggtaacctgccggtgcgcgcgctcttcacgcgcggc
gaggaccgggaccgcttcacccggcgctgtggcaccgacacagtggtgctctacgacgag
agcagcagcgactggaacgagaatacgggcggcgagtcggtgctcgggctgctgctcaag
aagctcaaggacgagggctgccgggcgttctacctggaaggtggcttcagtaagttccaa
gccgagttctccctgcattgcgagaccaatctagacggctcgtgtagcagcagctcgccg
ccgttgccagtgctggggctcgggggcctgcggatcagctctgactcttcctcggacatc
gagtctgaccttgaccgagaccccaatagtgcaacagactcggatggtagtccgctgtcc
aacagccagccttccttcccagtggagatcttgcccttcctctacttgggctgtgccaaa
gactccaccaacttggacgtgttggaggaattcggcatcaagtacatcttgaacgtcacc
cccaatttgccgaatctctttgagaacgcaggagagtttaaatacaagcaaatccccatc
tcggatcactggagccaaaacctgtcccagtttttccctgaggccatttctttcatagat
gaagcccggggcaagaactgtggtgtcttggtacattgcttggctggcattagccgctca
gtcactgtgactgtggcttaccttatgcagaagctcaatctgtcgatgaacgatgcctat
gacattgtcaaaatgaaaaaatccaacatatcccctaacttcaacttcatgggtcagctg
ctggacttcgagaggacgctgggactcagcagcccatgtgacaacagggttccagcacag
cagctgtattttaccaccccttccaaccagaatgtataccaggtggactctctgcaatct
acgtga

KEGG   Homo sapiens (human): 1849Help
Entry
1849              CDS       T01001                                 

Gene name
DUSP7, MKPX, PYST2
Definition
(RefSeq) dual specificity phosphatase 7
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1849 (DUSP7)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1849 (DUSP7)
    3.1.3.48  protein-tyrosine-phosphatase
     1849 (DUSP7)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1849 (DUSP7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q16829(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
3p21.2
AA seq 419 aa AA seqDB search
MKNQLRGPPARAHMSTSGAAAAGGTRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWL
QEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHAD
KERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQT
EYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSS
QPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISD
HWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDF
VKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
NT seq 1260 nt NT seq  +upstreamnt  +downstreamnt
atgaaaaaccagctccgcggccccccagcgcgggcgcacatgtcgacttcgggggcggcg
gcggctgggggcacccgggcggggtccgagcccggtgcggggtcggggtccggcgcaggc
accggggcgggcgcggcgacgggggcaggggccatgccctgcaagagcgccgagtggctg
caggaggagctggaggcgcgcggcggcgcgtccttgctgctgctcgactgccggccgcac
gagctcttcgagtcgtcgcacatcgagacggccatcaacctggccatcccgggcctcatg
ttgcgccgcctgcgcaagggcaacctgcccatccgctccatcatccccaaccacgccgac
aaggagcgcttcgccacgcgctgcaaggcggccaccgtgctgctctacgacgaggccacg
gccgagtggcagcccgagcccggcgctcccgcctccgtgctcggcctgctcctacagaag
ctgcgcgacgacggctgccaggcctactacctccaaggtggtttcaacaagtttcaaaca
gagtactctgagcactgcgagaccaacgtggacagctcttcctcgccgagcagctcgcca
cccacctcagtgctgggcctggggggcctgcgcatcagctctgactgctccgacggcgag
tcggaccgagagctgcccagcagtgccaccgagtcagacggcagccctgtgccatccagc
caaccagccttccctgtccagatcctgccctacctctacctcggctgcgccaaggactcc
accaacctggacgtgctcggcaagtatggcatcaagtatatcctcaatgtcacacccaac
ctacccaacgccttcgagcacggcggcgagttcacctacaagcagatccccatctctgac
cactggagccagaacctctcccagttcttccctgaggccatcagcttcattgacgaagcc
cgctccaagaagtgtggtgtcctggtgcactgcctggcaggcatcagccgctcagtgacg
gtcactgtggcctatctgatgcagaagatgaacctgtcactcaacgacgcctacgacttt
gtcaagaggaaaaagtccaacatctcgcccaacttcaacttcatggggcagctgctggac
tttgagcggacgctggggctaagcagcccgtgcgacaaccacgcgtcgagtgagcagctc
tacttttccacgcccaccaaccacaacctgttcccactcaatacgctggagtccacgtga

KEGG   Homo sapiens (human): 1850Help
Entry
1850              CDS       T01001                                 

Gene name
DUSP8, C11orf81, HB5, HVH-5, HVH8
Definition
(RefSeq) dual specificity phosphatase 8
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1850 (DUSP8)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1850 (DUSP8)
    3.1.3.48  protein-tyrosine-phosphatase
     1850 (DUSP8)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1850 (DUSP8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q13202(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
11p15.5
AA seq 625 aa AA seqDB search
MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQ
QGKVTIAELIQPAARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVA
ILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKD
LMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSC
QVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL
KLLAALQGDPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGGLSAGGEPPA
PPTPPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDGPGPPDPGEAP
KLCKLDSPSGAALGLSSPSPDSPDAAPEARPRPRRRPRPPAGSPARSPAHSLGLNFGDAA
RQTPRHGLSALSAPGLPGPGQPAGPGAWAPPLDSPGTPSPDGPWCFSPEGAQGAGGVLFA
PFGRAGAPGPGGGSDLRRREAARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEGMVEGR
ARGEELAALGKQASFSGSVEVIEVS
NT seq 1878 nt NT seq  +upstreamnt  +downstreamnt
atggctggggaccggctcccgaggaaggtgatggatgccaagaagctggccagcctgctg
cggggcgggcctggggggccgctggtcatcgacagccgctccttcgtggagtacaacagc
tggcatgtgctcagctccgtcaacatctgctgctccaagctggtgaagcggcggctgcag
cagggcaaggtgaccattgcggagctcatccagccggctgcacgcagccaggtggaggct
acggagccacaggacgtggtggtctatgaccagagcacgcgggacgccagcgtgctggcc
gcagacagcttcctctccatcctgctgagcaagctggacggctgcttcgacagcgtggcc
atcctcactgggggcttcgccaccttctcctcctgcttccccggcctctgcgagggcaag
cctgctgccctgctacccatgagcctctcccagccctgcctgcctgtgcccagcgtgggc
ctgacccgcatcctgcctcacctctacctgggctcgcagaaggacgtcctaaacaaggat
ctgatgacgcaaaatggaataagctacgtcctcaacgccagcaactcctgccccaagcct
gacttcatctgcgagagccgcttcatgcgggtccccatcaacgacaactactgtgaaaaa
ctgctgccctggctggacaagtccatcgagttcatcgataaagccaagctctccagctgc
caagtcatcgtccactgtctggctggcatctcccgctctgccaccatcgccatcgcctac
atcatgaagaccatgggcatgtcctccgacgacgcctacaggttcgtgaaggacaggcgc
ccgtccatctcgcccaacttcaacttcctgggccagctgctggagtacgagcgcagcctg
aagctgctggccgccctgcagggcgacccgggcaccccctcagggacgccggagcctccg
cccagtcctgccgccggggccccgctgccacggctgccaccacctacctcagagagcgct
gccacagggaatgcggctgccagggagggcggcctgagcgcgggcggggagccccccgcg
ccccccacgcccccggcgaccagcgcactgcagcagggcctgcgcggcctgcacctctcc
tcggaccgcctgcaggacactaaccgcctcaagcgctccttctccctggacatcaagtct
gcctacgcccctagcaggcggcccgacggccccgggccccccgaccccggcgaggccccg
aagctctgcaagctggacagcccgtcgggggccgcgctgggcctgtcctcgcccagcccg
gacagcccggacgccgcgcctgaggcgcgcccacggccccgccggcggccccggcccccc
gccggctcccccgcgcgctcccccgcgcacagcctcggcctgaacttcggcgatgcggcc
cggcagactccgcggcacggcctctcggccctgtcggcgcccgggctgcccggccctggc
cagccggccggccccggggcctgggcaccgccgctcgactccccaggcacgccgtcgccc
gacgggccctggtgcttcagccccgagggcgcacagggggcgggcggggtgctgtttgcg
cccttcggccgggcgggcgccccgggaccaggcggcggcagcgacctgcggcggcgggag
gcagcgagggctgagccccgggacgcgcggaccggctggcccgaggagccggccccggag
acgcagttcaagcgccgcagctgccagatggagttcgaggagggcatggtggaggggcgc
gcgcgcggcgaggagctggccgccctgggcaagcaggcgagcttctcgggcagcgtggag
gtcatcgaggtgtcctga

KEGG   Homo sapiens (human): 1852Help
Entry
1852              CDS       T01001                                 

Gene name
DUSP9, MKP-4, MKP4
Definition
(RefSeq) dual specificity phosphatase 9
  KO
K18498  
dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    1852 (DUSP9)
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    1852 (DUSP9)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1852 (DUSP9)
    3.1.3.48  protein-tyrosine-phosphatase
     1852 (DUSP9)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1852 (DUSP9)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q99956(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
Xq28
AA seq 384 aa AA seqDB search
MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLS
VRALLPGPPLQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLA
YYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADR
DSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNL
PNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTV
TVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQA
SAASNPPSFFTTPTSDGAFELAPT
NT seq 1155 nt NT seq  +upstreamnt  +downstreamnt
atggagggtctgggccgctcgtgcctgtggctgcgtcgggagctgtcgcccccgcggccg
cggctcctgctcctggactgccgcagccgcgagctgtacgagtcggcgcgcatcggtggg
gcgctgagcgtggccctgccggcgctcctgctgcgccgcctgcggaggggcagcctgtcg
gtgcgcgcgctcctgcctgggccgccgctgcagccgcccccgcctgcccccgtgctcctg
tacgaccagggcgggggccggcgccggcgcggggaggccgaggccgaggccgaggagtgg
gaggccgagtcggtgctgggcaccctgctgcagaagctgcgagaggaaggctacctggcc
tactacctccagggaggcttcagcagattccaggccgagtgccctcacctgtgtgagacc
agccttgctggccgtgccggctccagcatggcgccggtgcccggtccagtgcccgtggtg
gggttgggcagcctgtgcctgggctccgactgctctgatgcggaatccgaggctgaccgc
gactccatgagctgtggcctggattcggagggtgccacacccccaccagtggggctgcgg
gcatccttccctgtccagatcctgcccaacctctatctgggcagtgcccgggattccgcc
aatttggagagcctggccaaactgggcatccgctacatcctcaatgtcacccccaacctc
ccaaacttcttcgagaagaatggtgactttcactacaagcagatccccatctccgaccac
tggagccagaacctgtcgcggttctttccggaggccattgagttcattgatgaggccttg
tcccagaactgcggggtgctcgtccactgcttggcgggggtcagccgttctgtcaccgtc
actgtggcctacctcatgcagaagctccacctctctctcaacgatgcctatgacctggtc
aagaggaagaagtctaacatctcccccaacttcaacttcatggggcagttgctggacttt
gagcgcagcttgcggctggaggagcgccactcgcaggagcagggcagtggggggcaggca
tctgcggcctccaacccgccctccttcttcaccacccccaccagtgatggcgccttcgag
ctggcccccacctag

KEGG   Homo sapiens (human): 80824Help
Entry
80824             CDS       T01001                                 

Gene name
DUSP16, MKP-7, MKP7
Definition
(RefSeq) dual specificity phosphatase 16
  KO
K04459  
dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    80824 (DUSP16)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     80824 (DUSP16)
    3.1.3.48  protein-tyrosine-phosphatase
     80824 (DUSP16)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    80824 (DUSP16)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Pharos: 
Q9BY84(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
12p13.2
AA seq 665 aa AA seqDB search
MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ
DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL
LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM
QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV
LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN
QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV
PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF
SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ
SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH
SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR
QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME
IIEVS
NT seq 1998 nt NT seq  +upstreamnt  +downstreamnt
atggcccatgagatgattggaactcaaattgttactgagaggttggtggctctgctggaa
agtggaacggaaaaagtgctgctaattgatagccggccatttgtggaatacaatacatcc
cacattttggaagccattaatatcaactgctccaagcttatgaagcgaaggttgcaacag
gacaaagtgttaattacagagctcatccagcattcagcgaaacataaggttgacattgat
tgcagtcagaaggttgtagtttacgatcaaagctcccaagatgttgcctctctctcttca
gactgttttctcactgtacttctgggtaaactggagaagagcttcaactctgttcacctg
cttgcaggtgggtttgctgagttctctcgttgtttccctggcctctgtgaaggaaaatcc
actctagtccctacctgcatttctcagccttgcttacctgttgccaacattgggccaacc
cgaattcttcccaatctttatcttggctgccagcgagatgtcctcaacaaggagctgatg
cagcagaatgggattggttatgtgttaaatgccagcaatacctgtccaaagcctgacttt
atccccgagtctcatttcctgcgtgtgcctgtgaatgacagcttttgtgagaaaattttg
ccgtggttggacaaatcagtagatttcattgagaaagcaaaagcctccaatggatgtgtt
ctagtgcactgtttagctgggatctcccgctccgccaccatcgctatcgcctacatcatg
aagaggatggacatgtctttagatgaagcttacagatttgtgaaagaaaaaagacctact
atatctccaaacttcaattttctgggccaactcctggactatgagaagaagattaagaac
cagactggagcatcagggccaaagagcaaactcaagctgctgcacctggagaagccaaat
gaacctgtccctgctgtctcagagggtggacagaaaagcgagacgcccctcagtccaccc
tgtgccgactctgctacctcagaggcagcaggacaaaggcccgtgcatcccgccagcgtg
cccagcgtgcccagcgtgcagccgtcgctgttagaggacagcccgctggtacaggcgctc
agtgggctgcacctgtccgcagacaggctggaagacagcaataagctcaagcgttccttc
tctctggatatcaaatcagtttcatattcagccagcatggcagcatccttacatggcttc
tcctcatcagaagatgctttggaatactacaaaccttccactactctggatgggaccaac
aagctatgccagttctcccctgttcaggaactatcggagcagactcccgaaaccagtcct
gataaggaggaagccagcatccccaagaagctgcagaccgccaggccttcagacagccag
agcaagcgattgcattcggtcagaaccagcagcagtggcaccgcccagaggtccctttta
tctccactgcatcgaagtgggagcgtggaggacaattaccacaccagcttccttttcggc
ctttccaccagccagcagcacctcacgaagtctgctggcctgggccttaagggctggcac
tcggatatcttggccccccagacctctaccccttccctgaccagcagctggtattttgcc
acagagtcctcacacttctactctgcctcagccatctacggaggcagtgccagttactct
gcctacagctgcagccagctgcccacttgcggagaccaagtctattctgtgcgcaggcgg
cagaagccaagtgacagagctgactcgcggcggagctggcatgaagagagcccctttgaa
aagcagtttaaacgcagaagctgccaaatggaatttggagagagcatcatgtcagagaac
aggtcacgggaagagctggggaaagtgggcagtcagtctagcttttcgggcagcatggaa
atcattgaggtctcctga

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