KEGG T01001: 112398

Homo sapiens (human): 112398

Entry

112398 CDS T01001

Gene name

EGLN2, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1

Definition

egl nine homolog 2 (C. elegans) (EC:1.14.11.29)

Orthology

K09592

hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.-]

Organism

hsa Homo sapiens (human)

Pathway

hsa04066	HIF-1 signaling pathway
hsa05200	Pathways in cancer
hsa05211	Renal cell carcinoma

Class

Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:hsa04066]
Human Diseases; Cancers; Pathways in cancer [PATH:hsa05200]
Human Diseases; Cancers; Renal cell carcinoma [PATH:hsa05211]

SSDB

Motif

Pfam:

2OG-FeII_Oxy_3 2OG-FeII_Oxy 2OG-FeII_Oxy_4

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

19q13.2

AA seq 407 aa
MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAG
SGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRK
WAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALD
YIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQI
AWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDN
PHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEV
KPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT

NT seq 1224 nt +upstreamnt +downstreamnt
atggacagcccgtgccagccgcagcccctaagtcaggctctccctcagttaccagggtct
tcgtcagagcccttggagcctgagcctggccgggccaggatgggagtggagagttacctg
ccctgtcccctgctcccctcctaccactgtccaggagtgcctagtgaggcctcggcaggg
agtgggacccccagagccacagccacctctaccactgccagccctcttcgggacggtttt
ggcgggcaggatggtggtgagctgcggccgctgcagagtgaaggcgctgcagcgctggtc
accaaggggtgccagcgattggcagcccagggcgcacggcctgaggcccccaaacggaaa
tgggccgaggatggtggggatgccccttcacccagcaaacggccctgggccaggcaagag
aaccaggaggcagagcgggagggtggcatgagctgcagctgcagcagtggcagtggtgag
gccagtgctgggctgatggaggaggcgctgccctctgcgcccgagcgcctggccctggac
tatatcgtgccctgcatgcggtactacggcatctgcgtcaaggacagcttcctgggggca
gcactgggcggtcgcgtgctggccgaggtggaggccctcaaacggggtgggcgcctgcga
gacgggcagctagtgagccagagggcgatcccgccgcgcagcatccgtggggaccagatt
gcctgggtggaaggccatgaaccaggctgtcgaagcattggtgccctcatggcccatgtg
gacgccgtcatccgccactgcgcagggcggctgggcagctatgtcatcaacgggcgcacc
aaggccatggtggcgtgttacccaggcaacgggctcgggtacgtaaggcacgttgacaat
ccccacggcgatgggcgctgcatcacctgtatctattacctgaatcagaactgggacgtt
aaggtgcatggcggcctgctgcagatcttccctgagggccggcccgtggtagccaacatc
gagccactctttgaccggttgctcattttctggtctgaccggcggaacccccacgaggtg
aagccagcctatgccaccaggtacgccatcactgtctggtattttgatgccaaggagcgg
gcagcagccaaagacaagtatcagctagcatcaggacagaaaggtgtccaagtacctgta
tcacagccgcctacgcccacctag

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (35)   
   RefSeq(nuc) (3)   
   GenBank (16)   
   EMBL (16)   
Protein domain (3)   
   Pfam (3)   
All databases (63)   

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