KEGG   Homo sapiens (human): 11277Help
Entry
11277             CDS       T01001                                 

Gene name
TREX1, AGS1, CRV, DRN3, HERNS
Definition
three prime repair exonuclease 1 (EC:3.1.11.2)
Orthology
K10790  
three prime repair exonuclease 1 [EC:3.1.11.2]
Organism
hsa  Homo sapiens (human)
Pathway
Cytosolic DNA-sensing pathway
Disease
H00290  
Aicardi-Goutieres Syndrome (AGS)
H00291  
Familial chilblain lupus (FCL)
H01000  
Retinal vasculopathy with cerebral leukodystrophy (RVCL)
Class
Organismal Systems; Immune system; Cytosolic DNA-sensing pathway [PATH:hsa04623]
BRITE hierarchy
SSDB OrthologParalogGFIT
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
UniProt: 
Position
3p21.31
AA seq 304 aa AA seqDB search
MQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPPPRVVDKLSLC
VAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYD
FPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQS
PPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTT
TAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLA
TPGE
NT seq 915 nt NT seq  +upstreamnt  +downstreamnt
atgcagaccctcatctttttcgacatggaggccactggcttgcccttctcccagcccaag
gtcacggagctgtgcctgctggctgtccacagatgtgccctggagagcccccccacctct
caggggccacctcccacagttcctccaccaccgcgtgtggtagacaagctctccctgtgt
gtggctccggggaaggcctgcagccctgcagccagcgagatcacaggtctgagcacagct
gtgctggcagcgcatgggcgtcaatgttttgatgacaacctggccaacctgctcctagcc
ttcctgcggcgccagccacagccctggtgcctggtggcacacaatggtgaccgctacgac
ttccccctgctccaagcagagctggctatgctgggcctcaccagtgctctggatggtgcc
ttctgtgtggatagcatcactgcgctgaaggccctggagcgagcaagcagcccctcagaa
cacggcccaaggaagagctacagcctaggcagcatctacactcgcctgtatgggcagtcc
cctccagactcgcacacggctgagggtgatgtcctggccctgctcagcatctgtcagtgg
agaccacaggccctgctgcggtgggtggatgctcacgccaggcctttcggcaccatcagg
cccatgtatggggtcacagcctctgctaggaccaagccaagaccatctgctgtcacaacc
actgcacacctggccacaaccaggaacactagtcccagccttggagagagcaggggtacc
aaggatcttcctccagtgaaggaccctggagccctatccagggaggggctgctggcccca
ctgggtctgctggccatcctgaccttggcagtagccacactgtatggactatccctggcc
acacctggggagtag

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