KEGG T01001: 114112

Homo sapiens (human): 114112

Entry

114112 CDS T01001

Gene name

TXNRD3, TGR, TR2, TRXR3

Definition

thioredoxin reductase 3 (EC:1.8.1.9)

Orthology

K00384

thioredoxin reductase (NADPH) [EC:1.8.1.9]

Organism

hsa Homo sapiens (human)

Pathway

hsa00240	Pyrimidine metabolism
hsa00450	Selenocompound metabolism

Class

Metabolism; Nucleotide metabolism; Pyrimidine metabolism [PATH:hsa00240]
Metabolism; Metabolism of other amino acids; Selenocompound metabolism [PATH:hsa00450]

SSDB

Motif

Pfam:

Pyr_redox_2 Pyr_redox_dim Pyr_redox Glutaredoxin Pyr_redox_3 FAD_binding_2 Thi4 DAO HI0933_like FAD_oxidored GIDA NAD_binding_8 FAD_binding_3

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3H8Q

Position

3q21.3

AA seq 607 aa
MERSPPQSPGPGKAGDAPNRRSGHVRGARVLSPPGRRARLSSPGPSRSSEAREELRRHLV
GLIERSRVVIFSKSYCPHSTRVKELFSSLGVECNVLELDQVDDGARVQEVLSEITNQKTV
PNIFVNKVHVGGCDQTFQAYQSGLLQKLLQEDLAYDYDLIIIGGGSGGLSCAKEAAILGK
KVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLMHQAALLGQALCDSRKFGWEYNQQVRH
NWETMTKAIQNHISSLNWGYRLSLREKAVAYVNSYGEFVEHHKIKATNKKGQETYYTAAQ
FVIATGERPRYLGIQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDV
TVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKLKVLAKSTEG
TETIEGVYNTVLLAIGRDSCTRKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDIL
EDKPELTPVAIQSGKLLAQRLFGASLEKIYHTLFWPLEWTVAGRENNTCYAKIICNKFDH
DRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDI
TQKGCUG

NT seq 1824 nt +upstreamnt +downstreamnt
ctggagcggtcgccgccgcagtcgcccgggccgggaaaggcgggcgatgcccccaaccgc
cgctcgggccatgtccgaggggcgcgcgtgttgtcgccgccggggcgccgtgcccgcctg
tcgtcccccgggcccagccgctcgtccgaggcccgcgaggagctgcgccgccacctcgtg
ggcctcatcgagcgcagccgggtggtgatcttcagcaagagctactgtccccatagtact
cgggtgaaagaactcttttcttctttgggagtcgaatgtaatgtcttggaacttgatcaa
gttgatgatggggccagggttcaagaagtgctgtcagaaatcactaatcagaaaactgtg
cccaatattttcgtgaataaagtgcatgtaggtggatgtgaccaaactttccaggcatat
cagagtggtttgttacagaagctccttcaggaagatttggcatatgattatgatctcatc
atcatcggtggtggttctggaggcctttcatgtgcgaaggaagctgccattttgggaaag
aaagttatggtgctagactttgttgtcccgtcacctcagggcacatcctggggtcttggt
ggcacttgtgtaaatgtaggttgtattcctaagaaattgatgcatcaggctgcccttttg
gggcaggcattatgtgactcaaggaaatttggctgggaatataatcaacaagtgaggcac
aactgggagacaatgacaaaagcgattcagaaccacatcagctctctaaactggggctac
aggttgtctctgagggaaaaggctgtggcctatgtcaattcctatggagaatttgttgaa
catcataaaataaaggcaaccaataaaaaaggacaggagacttattatactgctgcacag
tttgtcatagcaacgggtgaaaggccacggtatttaggaatccaaggagataaagaatac
tgtattactagtgatgaccttttttctctgccttattgccctggcaaaacattagtggtg
ggtgcctcttatgttgccctggagtgtgcagggtttctggctggctttggcctagatgtc
acagttatggtacgctcaatccttctccgtggcttcgaccaagaaatggcagaaaaagtg
ggttcctacatggagcagcatggtgtgaagttcctacggaaattcatacctgtgatggtt
caacagttggagaaaggttcacctggaaagctgaaagtgttggctaaatccactgaagga
acagaaacaattgaaggagtctataacacagttttgttagctattggtcgtgactcctgt
acaaggaaaataggcttggagaagattggtgtcaaaattaatgagaagagtggaaaaata
cctgtaaatgatgtggaacagaccaatgtgccatatgtctatgctgttggtgatattttg
gaggataagccagagctcactcctgtcgccatacagtcaggcaagctgctagctcagaga
ctttttggggcctctttagaaaagatatatcatactttgttctggcctcttgaatggaca
gtagctggcagagagaacaacacttgttacgcaaagataatctgcaataaattcgaccat
gatcgggtgataggatttcatattcttggaccaaacgccggtgaggttacccaaggattt
gcagctgcaatgaaatgtgggctcacaaaacagctacttgatgacaccattggaattcac
cccacatgtggggaggtgttcacgactttggaaatcacaaagtcgtcaggactagacatc
actcagaaaggctgctgaggctag

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (6)   
   UniGene (1)   
   HGNC (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (14)   
   RefSeq(nuc) (2)   
   GenBank (6)   
   EMBL (6)   
3D Structure (1)   
   PDB (1)   
Protein domain (13)   
   Pfam (13)   
All databases (63)   

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