KEGG T01001: 1268

Homo sapiens (human): 1268

Entry

1268 CDS T01001

Gene name

CNR1, CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR

Definition

cannabinoid receptor 1 (brain)

Orthology

K04277

cannabinoid receptor 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04080	Neuroactive ligand-receptor interaction
hsa04723	Retrograde endocannabinoid signaling

Drug target

Dronabinol:

D00306

Nabilone:

D05099

Rimonabant:

D05731

Other:

D04717 D09009 D09349 D09362 D09363

Class

Environmental Information Processing; Signaling molecules and interaction; Neuroactive ligand-receptor interaction [PATH:hsa04080]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:hsa04723]

SSDB

Motif

Pfam:

7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx Flavi_NS4B DUF3671

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

6q14-q15

AA seq 472 aa
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL

NT seq 1419 nt +upstreamnt +downstreamnt
atgaagtcgatcctagatggccttgcagataccaccttccgcaccatcaccactgacctc
ctgtacgtgggctcaaatgacattcagtacgaagacatcaaaggtgacatggcatccaaa
ttagggtacttcccacagaaattccctttaacttcctttaggggaagtcccttccaagag
aagatgactgcgggagacaacccccagctagtcccagcagaccaggtgaacattacagaa
ttttacaacaagtctctctcgtccttcaaggagaatgaggagaacatccagtgtggggag
aacttcatggacatagagtgtttcatggtcctgaaccccagccagcagctggccattgca
gtcctgtccctcacgctgggcaccttcacggtcctggagaacctcctggtgctgtgcgtc
atcctccactcccgcagcctccgctgcaggccttcctaccacttcatcggcagcctggcg
gtggcagacctcctggggagtgtcatttttgtctacagcttcattgacttccacgtgttc
caccgcaaagatagccgcaacgtgtttctgttcaaactgggtggggtcacggcctccttc
actgcctccgtgggcagcctgttcctcacagccatcgacaggtacatatccattcacagg
cccctggcctataagaggattgtcaccaggcccaaggccgtggtggcgttttgcctgatg
tggaccatagccattgtgatcgccgtgctgcctctcctgggctggaactgcgagaaactg
caatctgtttgctcagacattttcccacacattgatgaaacctacctgatgttctggatc
ggggtcaccagcgtactgcttctgttcatcgtgtatgcgtacatgtatattctctggaag
gctcacagccacgccgtccgcatgattcagcgtggcacccagaagagcatcatcatccac
acgtctgaggatgggaaggtacaggtgacccggccagaccaagcccgcatggacattagg
ttagccaagaccctggtcctgatcctggtggtgttgatcatctgctggggccctctgctt
gcaatcatggtgtatgatgtctttgggaagatgaacaagctcattaagacggtgtttgca
ttctgcagtatgctctgcctgctgaactccaccgtgaaccccatcatctatgctctgagg
agtaaggacctgcgacacgctttccggagcatgtttccctcttgtgaaggcactgcgcag
cctctggataacagcatgggggactcggactgcctgcacaaacacgcaaacaatgcagcc
agtgttcacagggccgcagaaagctgcatcaagagcacggtcaagattgccaaggtaacc
atgtctgtgtccacagacacgtctgccgaggctctgtga

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (8)   
   KEGG DRUG (8)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (16)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (50)   
   RefSeq(nuc) (6)   
   GenBank (22)   
   EMBL (22)   
Protein domain (5)   
   Pfam (5)   
All databases (104)   

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