KEGG T01001: 1394

Homo sapiens (human): 1394

Entry

1394 CDS T01001

Gene name

CRHR1, CRF-R, CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRH-R-1, CRH-R1, CRH-R1h, CRHR, CRHR1L, CRHR1f

Definition

corticotropin releasing hormone receptor 1

Orthology

K04578

corticotropin releasing hormone receptor 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04080	Neuroactive ligand-receptor interaction
hsa04730	Long-term depression

Drug target

Corticorelin:

D03591 D03592 D03905

Other:

D09610 D09695 D10022

Class

Environmental Information Processing; Signaling molecules and interaction; Neuroactive ligand-receptor interaction [PATH:hsa04080]
Organismal Systems; Nervous system; Long-term depression [PATH:hsa04730]

SSDB

Motif

Pfam:

7tm_2 HRM Tissue_fac

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2L27

Position

17q12-q22

AA seq 444 aa
MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA
GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR
NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC
YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI
YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF
VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV
ARAMSIPTSPTRVSFHSIKQSTAV

NT seq 1335 nt +upstreamnt +downstreamnt
atgggagggcacccgcagctccgtctcgtcaaggcccttctccttctggggctgaacccc
gtctctgcctccctccaggaccagcactgcgagagcctgtccctggccagcaacatctca
ggactgcagtgcaacgcatccgtggacctcattggcacctgctggccccgcagccctgcg
gggcagctagtggttcggccctgccctgcctttttctatggtgtccgctacaataccaca
aacaatggctaccgggagtgcctggccaatggcagctgggccgcccgcgtgaattactcc
gagtgccaggagatcctcaatgaggagaaaaaaagcaaggtgcactaccatgtcgcagtc
atcatcaactacctgggccactgtatctccctggtggccctcctggtggcctttgtcctc
tttctgcggctcaggccaggctgcacccattggggtgaccaggcagatggagccctggag
gtgggggctccatggagtggtgccccatttcaggttcgaaggagcatccggtgcctgcga
aacatcatccactggaacctcatctccgccttcatcctgcgcaacgccacctggttcgtg
gtccagctaaccatgagccccgaggtccaccagagcaacgtgggctggtgcaggttggtg
acagccgcctacaactacttccatgtgaccaacttcttctggatgttcggcgagggctgc
tacctgcacacagccatcgtgctcacctactccactgaccggctgcgcaaatggatgttc
atctgcattggctggggtgtgcccttccccatcattgtggcctgggccattgggaagctg
tactacgacaatgagaagtgctggtttggcaaaaggcctggggtgtacaccgactacatc
taccagggccccatgatcctggtcctgctgatcaatttcatcttccttttcaacatcgtc
cgcatcctcatgaccaagctccgggcatccaccacgtctgagaccattcagtacaggaag
gctgtgaaagccactctggtgctgctgcccctcctgggcatcacctacatgctgttcttc
gtcaatcccggggaggatgaggtctcccgggtcgtcttcatctacttcaactccttcctg
gaatccttccagggcttctttgtgtctgtgttctactgtttcctcaatagtgaggtccgt
tctgccatccggaagaggtggcaccggtggcaggacaagcactcgatccgtgcccgagtg
gcccgtgccatgtccatccccacctccccaacccgtgtcagctttcacagcatcaagcag
tccacagcagtctga

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (6)   
   KEGG DRUG (6)   
Chemical substance (1)   
   KEGG COMPOUND (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (15)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (2)   
   RefSeq(pep) (5)   
DNA sequence (39)   
   RefSeq(nuc) (5)   
   GenBank (17)   
   EMBL (17)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (87)   

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