KEGG   Homo sapiens (human): 1435Help
Entry
1435              CDS       T01001                                 

Gene name
CSF1, CSF-1, MCSF
Definition
(RefSeq) colony stimulating factor 1
  KO
K05453  
macrophage colony-stimulating factor 1
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Osteoclast differentiation
Hematopoietic cell lineage
TNF signaling pathway
Rheumatoid arthritis
Drug target
Linifanib: 
Sunitinib (DG00712): 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    1435 (CSF1)
   04015 Rap1 signaling pathway
    1435 (CSF1)
   04010 MAPK signaling pathway
    1435 (CSF1)
   04668 TNF signaling pathway
    1435 (CSF1)
   04151 PI3K-Akt signaling pathway
    1435 (CSF1)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    1435 (CSF1)
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    1435 (CSF1)
  Development
   04380 Osteoclast differentiation
    1435 (CSF1)
 Human Diseases
  Immune diseases
   05323 Rheumatoid arthritis
    1435 (CSF1)
Cytokines [BR:hsa04052]
 PDGF family
  4-Helix bundle growth factors
   1435 (CSF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P09603(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
1p13.3
AA seq 554 aa AA seqDB search
MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
SPLTQDDRQVELPV
NT seq 1665 nt NT seq  +upstreamnt  +downstreamnt
atgaccgcgccgggcgccgccgggcgctgccctcccacgacatggctgggctccctgctg
ttgttggtctgtctcctggcgagcaggagtatcaccgaggaggtgtcggagtactgtagc
cacatgattgggagtggacacctgcagtctctgcagcggctgattgacagtcagatggag
acctcgtgccaaattacatttgagtttgtagaccaggaacagttgaaagatccagtgtgc
taccttaagaaggcatttctcctggtacaagacataatggaggacaccatgcgcttcaga
gataacacccccaatgccatcgccattgtgcagctgcaggaactctctttgaggctgaag
agctgcttcaccaaggattatgaagagcatgacaaggcctgcgtccgaactttctatgag
acacctctccagttgctggagaaggtcaagaatgtctttaatgaaacaaagaatctcctt
gacaaggactggaatattttcagcaagaactgcaacaacagctttgctgaatgctccagc
caagatgtggtgaccaagcctgattgcaactgcctgtaccccaaagccatccctagcagt
gacccggcctctgtctcccctcatcagcccctcgccccctccatggcccctgtggctggc
ttgacctgggaggactctgagggaactgagggcagctccctcttgcctggtgagcagccc
ctgcacacagtggatccaggcagtgccaagcagcggccacccaggagcacctgccagagc
tttgagccgccagagaccccagttgtcaaggacagcaccatcggtggctcaccacagcct
cgcccctctgtcggggccttcaaccccgggatggaggatattcttgactctgcaatgggc
actaattgggtcccagaagaagcctctggagaggccagtgagattcccgtaccccaaggg
acagagctttccccctccaggccaggagggggcagcatgcagacagagcccgccagaccc
agcaacttcctctcagcatcttctccactccctgcatcagcaaagggccaacagccggca
gatgtaactggtaccgccttgcccagggtgggccccgtgaggcccactggccaggactgg
aatcacaccccccagaagacagaccatccatctgccctgctcagagaccccccggagcca
ggctctcccaggatctcatcactgcgcccccagggcctcagcaacccctccaccctctct
gctcagccacagctttccagaagccactcctcgggcagcgtgctgccccttggggagctg
gagggcaggaggagcaccagggatcggaggagccccgcagagccagaaggaggaccagca
agtgaaggggcagccaggcccctgccccgttttaactccgttcctttgactgacacaggc
catgagaggcagtccgagggatcctccagcccgcagctccaggagtctgtcttccacctg
ctggtgcccagtgtcatcctggtcttgctggccgtcggaggcctcttgttctacaggtgg
aggcggcggagccatcaagagcctcagagagcggattctcccttggagcaaccagagggc
agccccctgactcaggatgacagacaggtggaactgccagtgtag

KEGG   Homo sapiens (human): 1942Help
Entry
1942              CDS       T01001                                 

Gene name
EFNA1, B61, ECKLG, EFL1, EPLG1, LERK-1, LERK1, TNFAIP4
Definition
(RefSeq) ephrin A1
  KO
K05462  
ephrin-A
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    1942 (EFNA1)
   04015 Rap1 signaling pathway
    1942 (EFNA1)
   04010 MAPK signaling pathway
    1942 (EFNA1)
   04151 PI3K-Akt signaling pathway
    1942 (EFNA1)
 Organismal Systems
  Development
   04360 Axon guidance
    1942 (EFNA1)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   1942 (EFNA1)
Cell adhesion molecules and their ligands [BR:hsa04516]
 7. Others
  EPHA1, EPH; Eph receptor A1 [KO:K05102]
   1942 (EFNA1)
  EPHA2, ECK; Eph receptor A2 [KO:K05103]
   1942 (EFNA1)
  EPHA3, HEK, TYRO4; Eph receptor A3 [KO:K05104]
   1942 (EFNA1)
  EPHA4, SEK, TYRO1; Eph receptor A4 [KO:K05105]
   1942 (EFNA1)
  EPHA5, EHK1, TYRO4; Eph receptor A5 [KO:K05106]
   1942 (EFNA1)
  EPHA6, EHK2; Eph receptor A6 [KO:K05107]
   1942 (EFNA1)
  EPHA7, EHK3, HEK11; EphA7 [KO:K05108]
   1942 (EFNA1)
  EPHA8, EEK; Eph receptor A8 [KO:K05109]
   1942 (EFNA1)
  EPHA10; Eph receptor A10 [KO:K08897]
   1942 (EFNA1)
  EPHB2, ERK, DRT; Eph receptor B2 [KO:K05111]
   1942 (EFNA1)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Axon guidance molecules
   1942 (EFNA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P20827(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
1q22
AA seq 205 aa AA seqDB search
MEFLWAPLLGLCCSLAAADRHTVFWNSSNPKFRNEDYTIHVQLNDYVDIICPHYEDHSVA
DAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLGKEF
KEGHSYYYISKPIHQHEDRCLRLKVTVSGKITHSPQAHDNPQEKRLAADDPEVRVLHSIG
HSAAPRLFPLAWTVLLLPLLLLQTP
NT seq 618 nt NT seq  +upstreamnt  +downstreamnt
atggagttcctctgggcccctctcttgggtctgtgctgcagtctggccgctgctgatcgc
cacaccgtcttctggaacagttcaaatcccaagttccggaatgaggactacaccatacat
gtgcagctgaatgactacgtggacatcatctgtccgcactatgaagatcactctgtggca
gacgctgccatggagcagtacatactgtacctggtggagcatgaggagtaccagctgtgc
cagccccagtccaaggaccaagtccgctggcagtgcaaccggcccagtgccaagcatggc
ccggagaagctgtctgagaagttccagcgcttcacacctttcaccctgggcaaggagttc
aaagaaggacacagctactactacatctccaaacccatccaccagcatgaagaccgctgc
ttgaggttgaaggtgactgtcagtggcaaaatcactcacagtcctcaggcccatgacaat
ccacaggagaagagacttgcagcagatgacccagaggtgcgggttctacatagcatcggt
cacagtgctgccccacgcctcttcccacttgcctggactgtgctgctccttccacttctg
ctgctgcaaaccccgtga

KEGG   Homo sapiens (human): 1943Help
Entry
1943              CDS       T01001                                 

Gene name
EFNA2, ELF-1, EPLG6, HEK7-L, LERK-6, LERK6
Definition
(RefSeq) ephrin A2
  KO
K05462  
ephrin-A
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    1943 (EFNA2)
   04015 Rap1 signaling pathway
    1943 (EFNA2)
   04010 MAPK signaling pathway
    1943 (EFNA2)
   04151 PI3K-Akt signaling pathway
    1943 (EFNA2)
 Organismal Systems
  Development
   04360 Axon guidance
    1943 (EFNA2)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   1943 (EFNA2)
Cell adhesion molecules and their ligands [BR:hsa04516]
 7. Others
  EPHA1, EPH; Eph receptor A1 [KO:K05102]
   1943 (EFNA2)
  EPHA2, ECK; Eph receptor A2 [KO:K05103]
   1943 (EFNA2)
  EPHA3, HEK, TYRO4; Eph receptor A3 [KO:K05104]
   1943 (EFNA2)
  EPHA4, SEK, TYRO1; Eph receptor A4 [KO:K05105]
   1943 (EFNA2)
  EPHA5, EHK1, TYRO4; Eph receptor A5 [KO:K05106]
   1943 (EFNA2)
  EPHA6, EHK2; Eph receptor A6 [KO:K05107]
   1943 (EFNA2)
  EPHA7, EHK3, HEK11; EphA7 [KO:K05108]
   1943 (EFNA2)
  EPHA8, EEK; Eph receptor A8 [KO:K05109]
   1943 (EFNA2)
  EPHA10; Eph receptor A10 [KO:K08897]
   1943 (EFNA2)
  EPHB2, ERK, DRT; Eph receptor B2 [KO:K05111]
   1943 (EFNA2)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Axon guidance molecules
   1943 (EFNA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
O43921(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
19p13.3
AA seq 213 aa AA seqDB search
MAPAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYT
VEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAP
GGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEA
PEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS
NT seq 642 nt NT seq  +upstreamnt  +downstreamnt
atggcgcccgcgcagcgcccgctgctcccgctgctgctcctgctgttaccgctgccgccg
ccgcccttcgcgcgcgccgaggacgccgcccgcgccaactcggaccgctacgccgtctac
tggaaccgcagcaaccccaggttccacgcaggcgcgggggacgacggcgggggctacacg
gtggaggtgagcatcaatgactacctggacatctactgcccgcactatggggcgccgctg
ccgccggccgagcgcatggagcactacgtgctgtacatggtcaacggcgagggccacgcc
tcctgcgaccaccgccagcgcggcttcaagcgctgggagtgcaaccggcccgcggcgccc
ggggggccgctcaagttctcggagaagttccagctcttcacgcccttctccctgggcttc
gagttccggcccggccacgagtattactacatctctgccacgcctcccaatgctgtggac
cggccctgcctgcgactgaaggtgtacgtgcggccgaccaacgagaccctgtacgaggct
cctgagcccatcttcaccagcaataactcgtgtagcagcccgggcggctgccgcctcttc
ctcagcaccatccccgtgctctggaccctcctgggttcctag

KEGG   Homo sapiens (human): 1944Help
Entry
1944              CDS       T01001                                 

Gene name
EFNA3, EFL2, EPLG3, Ehk1-L, LERK3
Definition
(RefSeq) ephrin A3
  KO
K05462  
ephrin-A
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Axon guidance
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    1944 (EFNA3)
   04015 Rap1 signaling pathway
    1944 (EFNA3)
   04010 MAPK signaling pathway
    1944 (EFNA3)
   04151 PI3K-Akt signaling pathway
    1944 (EFNA3)
 Organismal Systems
  Development
   04360 Axon guidance
    1944 (EFNA3)
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    1944 (EFNA3)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   1944 (EFNA3)
Cell adhesion molecules and their ligands [BR:hsa04516]
 7. Others
  EPHA1, EPH; Eph receptor A1 [KO:K05102]
   1944 (EFNA3)
  EPHA2, ECK; Eph receptor A2 [KO:K05103]
   1944 (EFNA3)
  EPHA3, HEK, TYRO4; Eph receptor A3 [KO:K05104]
   1944 (EFNA3)
  EPHA4, SEK, TYRO1; Eph receptor A4 [KO:K05105]
   1944 (EFNA3)
  EPHA5, EHK1, TYRO4; Eph receptor A5 [KO:K05106]
   1944 (EFNA3)
  EPHA6, EHK2; Eph receptor A6 [KO:K05107]
   1944 (EFNA3)
  EPHA7, EHK3, HEK11; EphA7 [KO:K05108]
   1944 (EFNA3)
  EPHA8, EEK; Eph receptor A8 [KO:K05109]
   1944 (EFNA3)
  EPHA10; Eph receptor A10 [KO:K08897]
   1944 (EFNA3)
  EPHB2, ERK, DRT; Eph receptor B2 [KO:K05111]
   1944 (EFNA3)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Axon guidance molecules
   1944 (EFNA3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P52797(Tbio)
UniProt: 
Position
1q21.3
AA seq 238 aa AA seqDB search
MAAAPLLLLLLLVPVPLLPLLAQGPGGALGNRHAVYWNSSNQHLRREGYTVQVNVNDYLD
IYCPHYNSSGVGPGAGPGPGGGAEQYVLYMVSRNGYRTCNASQGFKRWECNRPHAPHSPI
KFSEKFQRYSAFSLGYEFHAGHEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPT
LPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTFLAS
NT seq 717 nt NT seq  +upstreamnt  +downstreamnt
atggcggcggctccgctgctgctgctgctgctgctcgtgcccgtgccgctgctgccgctg
ctggcccaagggcccggaggggcgctgggaaaccggcatgcggtgtactggaacagctcc
aaccagcacctgcggcgagagggctacaccgtgcaggtgaacgtgaacgactatctggat
atttactgcccgcactacaacagctcgggggtgggccccggggcgggaccggggcccgga
ggcggggcagagcagtacgtgctgtacatggtgagccgcaacggctaccgcacctgcaac
gccagccagggcttcaagcgctgggagtgcaaccggccgcacgccccgcacagccccatc
aagttctcggagaagttccagcgctacagcgccttctctctgggctacgagttccacgcc
ggccacgagtactactacatctccacgcccactcacaacctgcactggaagtgtctgagg
atgaaggtgttcgtctgctgcgcctccacatcgcactccggggagaagccggtccccact
ctcccccagttcaccatgggccccaatgtgaagatcaacgtgctggaagactttgaggga
gagaaccctcaggtgcccaagcttgagaagagcatcagcgggaccagccccaaacgggaa
cacctgcccctggccgtgggcatcgccttcttcctcatgacgttcttggcctcctag

KEGG   Homo sapiens (human): 1945Help
Entry
1945              CDS       T01001                                 

Gene name
EFNA4, EFL4, EPLG4, LERK4
Definition
(RefSeq) ephrin A4
  KO
K05462  
ephrin-A
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    1945 (EFNA4)
   04015 Rap1 signaling pathway
    1945 (EFNA4)
   04010 MAPK signaling pathway
    1945 (EFNA4)
   04151 PI3K-Akt signaling pathway
    1945 (EFNA4)
 Organismal Systems
  Development
   04360 Axon guidance
    1945 (EFNA4)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   1945 (EFNA4)
Cell adhesion molecules and their ligands [BR:hsa04516]
 7. Others
  EPHA1, EPH; Eph receptor A1 [KO:K05102]
   1945 (EFNA4)
  EPHA2, ECK; Eph receptor A2 [KO:K05103]
   1945 (EFNA4)
  EPHA3, HEK, TYRO4; Eph receptor A3 [KO:K05104]
   1945 (EFNA4)
  EPHA4, SEK, TYRO1; Eph receptor A4 [KO:K05105]
   1945 (EFNA4)
  EPHA5, EHK1, TYRO4; Eph receptor A5 [KO:K05106]
   1945 (EFNA4)
  EPHA6, EHK2; Eph receptor A6 [KO:K05107]
   1945 (EFNA4)
  EPHA7, EHK3, HEK11; EphA7 [KO:K05108]
   1945 (EFNA4)
  EPHA8, EEK; Eph receptor A8 [KO:K05109]
   1945 (EFNA4)
  EPHA10; Eph receptor A10 [KO:K08897]
   1945 (EFNA4)
  EPHB2, ERK, DRT; Eph receptor B2 [KO:K05111]
   1945 (EFNA4)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Axon guidance molecules
   1945 (EFNA4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P52798(Tbio)
UniProt: 
Position
1q21.3
AA seq 201 aa AA seqDB search
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPH
YEGPGPPEGPETFALYMVDWPGYESCQAEGPRAYKRWVCSLPFGHVQFSEKIQRFTPFSL
GFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERKSESAHPVGSPGESGTSGWRGGDT
PSPLCLLLLLLLLILRLLRIL
NT seq 606 nt NT seq  +upstreamnt  +downstreamnt
atgcggctgctgcccctgctgcggactgtcctctgggccgcgttcctcggctcccctctg
cgcgggggctccagcctccgccacgtagtctactggaactccagtaaccccaggttgctt
cgaggagacgccgtggtggagctgggcctcaacgattacctagacattgtctgcccccac
tacgaaggcccagggccccctgagggccccgagacgtttgctttgtacatggtggactgg
ccaggctatgagtcctgccaggcagagggcccccgggcctacaagcgctgggtgtgctcc
ctgccctttggccatgttcaattctcagagaagattcagcgcttcacacccttctccctc
ggctttgagttcttacctggagagacttactactacatctcggtgcccactccagagagt
tctggccagtgcttgaggctccaggtgtctgtctgctgcaaggagaggaagtctgagtca
gcccatcctgttgggagccctggagagagtggcacatcagggtggcgagggggggacact
cccagccccctctgtctcttgctattactgctgcttctgattcttcgtcttctgcgaatt
ctgtga

KEGG   Homo sapiens (human): 1946Help
Entry
1946              CDS       T01001                                 

Gene name
EFNA5, AF1, EFL5, EPLG7, GLC1M, LERK7, RAGS
Definition
(RefSeq) ephrin A5
  KO
K05462  
ephrin-A
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    1946 (EFNA5)
   04015 Rap1 signaling pathway
    1946 (EFNA5)
   04010 MAPK signaling pathway
    1946 (EFNA5)
   04151 PI3K-Akt signaling pathway
    1946 (EFNA5)
 Organismal Systems
  Development
   04360 Axon guidance
    1946 (EFNA5)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   1946 (EFNA5)
Cell adhesion molecules and their ligands [BR:hsa04516]
 7. Others
  EPHA1, EPH; Eph receptor A1 [KO:K05102]
   1946 (EFNA5)
  EPHA2, ECK; Eph receptor A2 [KO:K05103]
   1946 (EFNA5)
  EPHA3, HEK, TYRO4; Eph receptor A3 [KO:K05104]
   1946 (EFNA5)
  EPHA4, SEK, TYRO1; Eph receptor A4 [KO:K05105]
   1946 (EFNA5)
  EPHA5, EHK1, TYRO4; Eph receptor A5 [KO:K05106]
   1946 (EFNA5)
  EPHA6, EHK2; Eph receptor A6 [KO:K05107]
   1946 (EFNA5)
  EPHA7, EHK3, HEK11; EphA7 [KO:K05108]
   1946 (EFNA5)
  EPHA8, EEK; Eph receptor A8 [KO:K05109]
   1946 (EFNA5)
  EPHA10; Eph receptor A10 [KO:K08897]
   1946 (EFNA5)
  EPHB2, ERK, DRT; Eph receptor B2 [KO:K05111]
   1946 (EFNA5)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Axon guidance molecules
   1946 (EFNA5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P52803(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
5q21.3
AA seq 228 aa AA seqDB search
MLHVEMLTLVFLVLWMCVFSQDPGSKAVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDV
FCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQL
FTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDK
VENSLEPADDTVHESAEPSRGENAAQTPRIPSRLLAILLFLLAMLLTL
NT seq 687 nt NT seq  +upstreamnt  +downstreamnt
atgttgcacgtggagatgttgacgctggtgtttctggtgctctggatgtgtgtgttcagc
caggacccgggctccaaggccgtcgccgaccgctacgctgtctactggaacagcagcaac
cccagattccagaggggtgactaccatattgatgtctgtatcaatgactacctggatgtt
ttctgccctcactatgaggactccgtcccagaagataagactgagcgctatgtcctctac
atggtgaactttgatggctacagtgcctgcgaccacacttccaaagggttcaagagatgg
gaatgtaaccggcctcactctccaaatggaccgctgaagttctctgaaaaattccagctc
ttcactcccttttctctaggatttgaattcaggccaggccgagaatatttctacatctcc
tctgcaatcccagataatggaagaaggtcctgtctaaagctcaaagtctttgtgagacca
acaaatagctgtatgaaaactataggtgttcatgatcgtgttttcgatgttaacgacaaa
gtagaaaattcattagaaccagcagatgacaccgtacatgagtcagccgagccatcccgc
ggcgagaacgcggcacaaacaccaaggatacccagccgccttttggcaatcctactgttc
ctcctggcgatgcttttgacattatag

KEGG   Homo sapiens (human): 1950Help
Entry
1950              CDS       T01001                                 

Gene name
EGF, HOMG4, URG
Definition
(RefSeq) epidermal growth factor
  KO
K04357  
epidermal growth factor
Organism
hsa  Homo sapiens (human)
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Regulation of actin cytoskeleton
Hepatitis C
Human papillomavirus infection
Pathways in cancer
Colorectal cancer
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Bladder cancer
Non-small cell lung cancer
Breast cancer
Gastric cancer
Choline metabolism in cancer
Network
N00001  
EGF-EGFR-RAS-ERK signaling pathway
N00021  
EGF-ERBB2-RAS-ERK signaling pathway
N00022  
ERBB2-overexpression to RAS-ERK signaling pathway
N00023  
EGF-EGFR-PLCG-ERK signaling pathway
N00026  
EGF-EGFR-PLCG-CAMK signaling pathway
N00030  
EGF-EGFR-RAS-PI3K signaling pathway
N00033  
EGF-EGFR-PI3K signaling pathway
N00034  
ERBB2-overexpression to PI3K signaling pathway
N00094  
EGF-Jak-STAT signaling pathway
N00095  
ERBB2-overexpression to EGF-Jak-STAT signaling pathway
N00096  
EGF-EGFR-RAS-RASSF1 signaling pathway
N00103  
EGF-EGFR-RAS-RalGDS signaling pathway
N00147  
EGF-EGFR-PLCG-calcineurin signaling pathway
N00252  
Amplified ERBB2 to RAS-ERK signaling pathway
N00253  
Amplified ERBB2 to PI3K signaling pathway
N00276  
EGF-overexpression to RAS-ERK signaling pathway
N00281  
EGF-overexpression to PI3K signaling pathway
Disease
H00020  
Colorectal cancer
H01210  
Hypomagnesemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    1950 (EGF)
   04015 Rap1 signaling pathway
    1950 (EGF)
   04010 MAPK signaling pathway
    1950 (EGF)
   04012 ErbB signaling pathway
    1950 (EGF)
   04630 Jak-STAT signaling pathway
    1950 (EGF)
   04066 HIF-1 signaling pathway
    1950 (EGF)
   04068 FoxO signaling pathway
    1950 (EGF)
   04072 Phospholipase D signaling pathway
    1950 (EGF)
   04151 PI3K-Akt signaling pathway
    1950 (EGF)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    1950 (EGF)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    1950 (EGF)
   04540 Gap junction
    1950 (EGF)
  Cell motility
   04810 Regulation of actin cytoskeleton
    1950 (EGF)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    1950 (EGF)
   05231 Choline metabolism in cancer
    1950 (EGF)
   05210 Colorectal cancer
    1950 (EGF)
   05212 Pancreatic cancer
    1950 (EGF)
   05226 Gastric cancer
    1950 (EGF)
   05214 Glioma
    1950 (EGF)
   05218 Melanoma
    1950 (EGF)
   05219 Bladder cancer
    1950 (EGF)
   05215 Prostate cancer
    1950 (EGF)
   05213 Endometrial cancer
    1950 (EGF)
   05224 Breast cancer
    1950 (EGF)
   05223 Non-small cell lung cancer
    1950 (EGF)
  Infectious diseases
   05160 Hepatitis C
    1950 (EGF)
   05165 Human papillomavirus infection
    1950 (EGF)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    1950 (EGF)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   1950 (EGF)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P01133(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
4q25
AA seq 1207 aa AA seqDB search
MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRID
TEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSG
MAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAG
SLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHI
SKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHP
LAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNEC
AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL
CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASG
PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERAN
MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQP
RGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCD
AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVR
LQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC
LALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
SMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
EGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHL
REDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
ELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRS
RRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGM
GTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPP
HQMELTQ
NT seq 3624 nt NT seq  +upstreamnt  +downstreamnt
atgctgctcactcttatcattctgttgccagtagtttcaaaatttagttttgttagtctc
tcagcaccgcagcactggagctgtcctgaaggtactctcgcaggaaatgggaattctact
tgtgtgggtcctgcacccttcttaattttctcccatggaaatagtatctttaggattgac
acagaaggaaccaattatgagcaattggtggtggatgctggtgtctcagtgatcatggat
tttcattataatgagaaaagaatctattgggtggatttagaaagacaacttttgcaaaga
gtttttctgaatgggtcaaggcaagagagagtatgtaatatagagaaaaatgtttctgga
atggcaataaattggataaatgaagaagttatttggtcaaatcaacaggaaggaatcatt
acagtaacagatatgaaaggaaataattcccacattcttttaagtgctttaaaatatcct
gcaaatgtagcagttgatccagtagaaaggtttatattttggtcttcagaggtggctgga
agcctttatagagcagatctcgatggtgtgggagtgaaggctctgttggagacatcagag
aaaataacagctgtgtcattggatgtgcttgataagcggctgttttggattcagtacaac
agagaaggaagcaattctcttatttgctcctgtgattatgatggaggttctgtccacatt
agtaaacatccaacacagcataatttgtttgcaatgtccctttttggtgaccgtatcttc
tattcaacatggaaaatgaagacaatttggatagccaacaaacacactggaaaggacatg
gttagaattaacctccattcatcatttgtaccacttggtgaactgaaagtagtgcatcca
cttgcacaacccaaggcagaagatgacacttgggagcctgagcagaaactttgcaaattg
aggaaaggaaactgcagcagcactgtgtgtgggcaagacctccagtcacacttgtgcatg
tgtgcagagggatacgccctaagtcgagaccggaagtactgtgaagatgttaatgaatgt
gctttttggaatcatggctgtactcttgggtgtaaaaacacccctggatcctattactgc
acgtgccctgtaggatttgttctgcttcctgatgggaaacgatgtcatcaacttgtttcc
tgtccacgcaatgtgtctgaatgcagccatgactgtgttctgacatcagaaggtccctta
tgtttctgtcctgaaggctcagtgcttgagagagatgggaaaacatgtagcggttgttcc
tcacccgataatggtggatgtagccagctctgcgttcctcttagcccagtatcctgggaa
tgtgattgctttcctgggtatgacctacaactggatgaaaaaagctgtgcagcttcagga
ccacaaccatttttgctgtttgccaattctcaagatattcgacacatgcattttgatgga
acagactatggaactctgctcagccagcagatgggaatggtttatgccctagatcatgac
cctgtggaaaataagatatactttgcccatacagccctgaagtggatagagagagctaat
atggatggttcccagcgagaaaggcttattgaggaaggagtagatgtgccagaaggtctt
gctgtggactggattggccgtagattctattggacagacagagggaaatctctgattgga
aggagtgatttaaatgggaaacgttccaaaataatcactaaggagaacatctctcaacca
cgaggaattgctgttcatccaatggccaagagattattctggactgatacagggattaat
ccacgaattgaaagttcttccctccaaggccttggccgtctggttatagccagctctgat
ctaatctggcccagtggaataacgattgacttcttaactgacaagttgtactggtgcgat
gccaagcagtctgtgattgaaatggccaatctggatggttcaaaacgccgaagacttacc
cagaatgatgtaggtcacccatttgctgtagcagtgtttgaggattatgtgtggttctca
gattgggctatgccatcagtaatgagagtaaacaagaggactggcaaagatagagtacgt
ctccaaggcagcatgctgaagccctcatcactggttgtggttcatccattggcaaaacca
ggagcagatccctgcttatatcaaaacggaggctgtgaacatatttgcaaaaagaggctt
ggaactgcttggtgttcgtgtcgtgaaggttttatgaaagcctcagatgggaaaacgtgt
ctggctctggatggtcatcagctgttggcaggtggtgaagttgatctaaagaaccaagta
acaccattggacatcttgtccaagactagagtgtcagaagataacattacagaatctcaa
cacatgctagtggctgaaatcatggtgtcagatcaagatgactgtgctcctgtgggatgc
agcatgtatgctcggtgtatttcagagggagaggatgccacatgtcagtgtttgaaagga
tttgctggggatggaaaactatgttctgatatagatgaatgtgagatgggtgtcccagtg
tgcccccctgcctcctccaagtgcatcaacaccgaaggtggttatgtctgccggtgctca
gaaggctaccaaggagatgggattcactgtcttgatattgatgagtgccaactgggggag
cacagctgtggagagaatgccagctgcacaaatacagagggaggctatacctgcatgtgt
gctggacgcctgtctgaaccaggactgatttgccctgactctactccaccccctcacctc
agggaagatgaccaccactattccgtaagaaatagtgactctgaatgtcccctgtcccac
gatgggtactgcctccatgatggtgtgtgcatgtatattgaagcattggacaagtatgca
tgcaactgtgttgttggctacatcggggagcgatgtcagtaccgagacctgaagtggtgg
gaactgcgccacgctggccacgggcagcagcagaaggtcatcgtggtggctgtctgcgtg
gtggtgcttgtcatgctgctcctcctgagcctgtggggggcccactactacaggactcag
aagctgctatcgaaaaacccaaagaatccttatgaggagtcgagcagagatgtgaggagt
cgcaggcctgctgacactgaggatgggatgtcctcttgccctcaaccttggtttgtggtt
ataaaagaacaccaagacctcaagaatgggggtcaaccagtggctggtgaggatggccag
gcagcagatgggtcaatgcaaccaacttcatggaggcaggagccccagttatgtggaatg
ggcacagagcaaggctgctggattccagtatccagtgataagggctcctgtccccaggta
atggagcgaagctttcatatgccctcctatgggacacagacccttgaagggggtgtcgag
aagccccattctctcctatcagctaacccattatggcaacaaagggccctggacccacca
caccaaatggagctgactcagtga

KEGG   Homo sapiens (human): 2246Help
Entry
2246              CDS       T01001                                 

Gene name
FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1
Definition
(RefSeq) fibroblast growth factor 1
  KO
K18496  
fibroblast growth factor 1
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Hippo signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2246 (FGF1)
   04015 Rap1 signaling pathway
    2246 (FGF1)
   04010 MAPK signaling pathway
    2246 (FGF1)
   04390 Hippo signaling pathway
    2246 (FGF1)
   04151 PI3K-Akt signaling pathway
    2246 (FGF1)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    2246 (FGF1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2246 (FGF1)
   05226 Gastric cancer
    2246 (FGF1)
   05218 Melanoma
    2246 (FGF1)
   05224 Breast cancer
    2246 (FGF1)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2246 (FGF1)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     2246 (FGF1)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     2246 (FGF1)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     2246 (FGF1)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     2246 (FGF1)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   2246 (FGF1)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   2246 (FGF1)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2246 (FGF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P05230(Tchem)
UniProt: 
Structure
PDB: 

Jmol
Position
5q31.3
AA seq 155 aa AA seqDB search
MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQ
LSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEK
NWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
NT seq 468 nt NT seq  +upstreamnt  +downstreamnt
atggctgaaggggaaatcaccaccttcacagccctgaccgagaagtttaatctgcctcca
gggaattacaagaagcccaaactcctctactgtagcaacgggggccacttcctgaggatc
cttccggatggcacagtggatgggacaagggacaggagcgaccagcacattcagctgcag
ctcagtgcggaaagcgtgggggaggtgtatataaagagtaccgagactggccagtacttg
gccatggacaccgacgggcttttatacggctcacagacaccaaatgaggaatgtttgttc
ctggaaaggctggaggagaaccattacaacacctatatatccaagaagcatgcagagaag
aattggtttgttggcctcaagaagaatgggagctgcaaacgcggtcctcggactcactat
ggccagaaagcaatcttgtttctccccctgccagtctcttctgattaa

KEGG   Homo sapiens (human): 2247Help
Entry
2247              CDS       T01001                                 

Gene name
FGF2, BFGF, FGF-2, FGFB, HBGF-2
Definition
(RefSeq) fibroblast growth factor 2
  KO
K18497  
fibroblast growth factor 2
Organism
hsa  Homo sapiens (human)
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Kaposi's sarcoma-associated herpesvirus infection
Pathways in cancer
Proteoglycans in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2247 (FGF2)
   04015 Rap1 signaling pathway
    2247 (FGF2)
   04010 MAPK signaling pathway
    2247 (FGF2)
   04151 PI3K-Akt signaling pathway
    2247 (FGF2)
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    2247 (FGF2)
  Cell motility
   04810 Regulation of actin cytoskeleton
    2247 (FGF2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2247 (FGF2)
   05205 Proteoglycans in cancer
    2247 (FGF2)
   05226 Gastric cancer
    2247 (FGF2)
   05218 Melanoma
    2247 (FGF2)
   05224 Breast cancer
    2247 (FGF2)
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    2247 (FGF2)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    2247 (FGF2)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2247 (FGF2)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     2247 (FGF2)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     2247 (FGF2)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     2247 (FGF2)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     2247 (FGF2)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   2247 (FGF2)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   2247 (FGF2)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2247 (FGF2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P09038(Tchem)
UniProt: 
Structure
PDB: 

Jmol
Position
4q28.1
AA seq 288 aa AA seqDB search
MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAA
GSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAA
PAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDG
RVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERL
ESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
NT seq 867 nt NT seq  +upstreamnt  +downstreamnt
ctggtgggtgtggggggtggagatgtagaagatgtgacgccgcggcccggcgggtgccag
attagcggacgcggtgcccgcggttgcaacgggatcccgggcgctgcagcttgggaggcg
gctctccccaggcggcgtccgcggagacacccatccgtgaaccccaggtcccgggccgcc
ggctcgccgcgcaccaggggccggcggacagaagagcggccgagcggctcgaggctgggg
gaccgcgggcgcggccgcgcgctgccgggcgggaggctggggggccggggccggggccgt
gccccggagcgggtcggaggccggggccggggccgggggacggcggctccccgcgcggct
ccagcggctcggggatcccggccgggccccgcagggaccatggcagccgggagcatcacc
acgctgcccgccttgcccgaggatggcggcagcggcgccttcccgcccggccacttcaag
gaccccaagcggctgtactgcaaaaacgggggcttcttcctgcgcatccaccccgacggc
cgagttgacggggtccgggagaagagcgaccctcacatcaagctacaacttcaagcagaa
gagagaggagttgtgtctatcaaaggagtgtgtgctaaccgttacctggctatgaaggaa
gatggaagattactggcttctaaatgtgttacggatgagtgtttcttttttgaacgattg
gaatctaataactacaatacttaccggtcaaggaaatacaccagttggtatgtggcactg
aaacgaactgggcagtataaacttggatccaaaacaggacctgggcagaaagctatactt
tttcttccaatgtctgctaagagctga

KEGG   Homo sapiens (human): 2248Help
Entry
2248              CDS       T01001                                 

Gene name
FGF3, HBGF-3, INT2
Definition
(RefSeq) fibroblast growth factor 3
  KO
K04358  
fibroblast growth factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Disease
H00041  
Kaposi's sarcoma
H00605  
Deafness, autosomal recessive
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2248 (FGF3)
   04015 Rap1 signaling pathway
    2248 (FGF3)
   04010 MAPK signaling pathway
    2248 (FGF3)
   04151 PI3K-Akt signaling pathway
    2248 (FGF3)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    2248 (FGF3)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2248 (FGF3)
   05226 Gastric cancer
    2248 (FGF3)
   05218 Melanoma
    2248 (FGF3)
   05224 Breast cancer
    2248 (FGF3)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2248 (FGF3)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     2248 (FGF3)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     2248 (FGF3)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     2248 (FGF3)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     2248 (FGF3)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   2248 (FGF3)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   2248 (FGF3)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2248 (FGF3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P11487(Tbio)
UniProt: 
Position
11q13.3
AA seq 239 aa AA seqDB search
MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLHP
SGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVER
IHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLP
RVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH
NT seq 720 nt NT seq  +upstreamnt  +downstreamnt
atgggcctaatctggctgctactgctcagcctgctggagcccggctggcccgcagcgggc
cctggggcgcggttgcggcgcgatgcgggcggccgtggcggcgtctacgagcaccttggc
ggggcgccccggcgccgcaagctctactgcgccacgaagtaccacctccagctgcacccg
agcggccgcgtcaacggcagcctggagaacagcgcctacagtattttggagataacggca
gtggaggtgggcattgtggccatcaggggtctcttctccgggcggtacctggccatgaac
aagaggggacgactctatgcttcggagcactacagcgccgagtgcgagtttgtggagcgg
atccacgagctgggctataatacgtatgcctcccggctgtaccggacggtgtctagtacg
cctggggcccgccggcagcccagcgccgagagactgtggtacgtgtctgtgaacggcaag
ggccggccccgcaggggcttcaagacccgccgcacacagaagtcctccctgttcctgccc
cgcgtgctggaccacagggaccacgagatggtgcggcagctacagagtgggctgcccaga
ccccctggtaagggggtccagccccgacggcggcggcagaagcagagcccggataacctg
gagccctctcacgttcaggcttcgagactgggctcccagctggaggccagtgcgcactag

KEGG   Homo sapiens (human): 2249Help
Entry
2249              CDS       T01001                                 

Gene name
FGF4, FGF-4, HBGF-4, HST, HST-1, HSTF-1, HSTF1, K-FGF, KFGF
Definition
(RefSeq) fibroblast growth factor 4
  KO
K04358  
fibroblast growth factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2249 (FGF4)
   04015 Rap1 signaling pathway
    2249 (FGF4)
   04010 MAPK signaling pathway
    2249 (FGF4)
   04151 PI3K-Akt signaling pathway
    2249 (FGF4)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    2249 (FGF4)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2249 (FGF4)
   05226 Gastric cancer
    2249 (FGF4)
   05218 Melanoma
    2249 (FGF4)
   05224 Breast cancer
    2249 (FGF4)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2249 (FGF4)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     2249 (FGF4)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     2249 (FGF4)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     2249 (FGF4)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     2249 (FGF4)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   2249 (FGF4)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   2249 (FGF4)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2249 (FGF4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P08620(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
11q13.3
AA seq 206 aa AA seqDB search
MSGPGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPV
AAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSP
VERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMFIA
LSKNGKTKKGNRVSPTMKVTHFLPRL
NT seq 621 nt NT seq  +upstreamnt  +downstreamnt
atgtcggggcccgggacggccgcggtagcgctgctcccggcggtcctgctggccttgctg
gcgccctgggcgggccgagggggcgccgccgcacccactgcacccaacggcacgctggag
gccgagctggagcgccgctgggagagcctggtggcgctctcgttggcgcgcctgccggtg
gcagcgcagcccaaggaggcggccgtccagagcggcgccggcgactacctgctgggcatc
aagcggctgcggcggctctactgcaacgtgggcatcggcttccacctccaggcgctcccc
gacggccgcatcggcggcgcgcacgcggacacccgcgacagcctgctggagctctcgccc
gtggagcggggcgtggtgagcatcttcggcgtggccagccggttcttcgtggccatgagc
agcaagggcaagctctatggctcgcccttcttcaccgatgagtgcacgttcaaggagatt
ctccttcccaacaactacaacgcctacgagtcctacaagtaccccggcatgttcatcgcc
ctgagcaagaatgggaagaccaagaaggggaaccgagtgtcgcccaccatgaaggtcacc
cacttcctccccaggctgtga

KEGG   Homo sapiens (human): 2250Help
Entry
2250              CDS       T01001                                 

Gene name
FGF5, HBGF-5, Smag-82, TCMGLY
Definition
(RefSeq) fibroblast growth factor 5
  KO
K04358  
fibroblast growth factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Disease
H01905  
Trichomegaly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2250 (FGF5)
   04015 Rap1 signaling pathway
    2250 (FGF5)
   04010 MAPK signaling pathway
    2250 (FGF5)
   04151 PI3K-Akt signaling pathway
    2250 (FGF5)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    2250 (FGF5)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2250 (FGF5)
   05226 Gastric cancer
    2250 (FGF5)
   05218 Melanoma
    2250 (FGF5)
   05224 Breast cancer
    2250 (FGF5)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2250 (FGF5)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     2250 (FGF5)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     2250 (FGF5)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     2250 (FGF5)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     2250 (FGF5)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   2250 (FGF5)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   2250 (FGF5)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2250 (FGF5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P12034(Tbio)
UniProt: 
Position
4q21.21
AA seq 268 aa AA seqDB search
MSLSFLLLLFFSHLILSAWAHGEKRLAPKGQPGPAATDRNPRGSSSRQSSSSAMSSSSAS
SSPAASLGSQGSGLEQSSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEANMLSV
LEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFTDDCKFRERFQENSYNTYASAIHR
TEKTGREWYVALNKRGKAKRGCSPRVKPQHISTHFLPRFKQSEQPELSFTVTVPEKKKPP
SPIKPKIPLSAPRKNTNSVKYRLKFRFG
NT seq 807 nt NT seq  +upstreamnt  +downstreamnt
atgagcttgtccttcctcctcctcctcttcttcagccacctgatcctcagcgcctgggct
cacggggagaagcgtctcgcccccaaagggcaacccggacccgctgccactgataggaac
cctagaggctccagcagcagacagagcagcagtagcgctatgtcttcctcttctgcctcc
tcctcccccgcagcttctctgggcagccaaggaagtggcttggagcagagcagtttccag
tggagcccctcggggcgccggaccggcagcctctactgcagagtgggcatcggtttccat
ctgcagatctacccggatggcaaagtcaatggatcccacgaagccaatatgttaagtgtt
ttggaaatatttgctgtgtctcaggggattgtaggaatacgaggagttttcagcaacaaa
tttttagcgatgtcaaaaaaaggaaaactccatgcaagtgccaagttcacagatgactgc
aagttcagggagcgttttcaagaaaatagctataatacctatgcctcagcaatacataga
actgaaaaaacagggcgggagtggtatgtggccctgaataaaagaggaaaagccaaacga
gggtgcagcccccgggttaaaccccagcatatctctacccattttctgccaagattcaag
cagtcggagcagccagaactttctttcacggttactgttcctgaaaagaaaaagccacct
agccctatcaagccaaagattcccctttctgcacctcggaaaaataccaactcagtgaaa
tacagactcaagtttcgctttggataa

KEGG   Homo sapiens (human): 2251Help
Entry
2251              CDS       T01001                                 

Gene name
FGF6, HBGF-6, HST2
Definition
(RefSeq) fibroblast growth factor 6
  KO
K04358  
fibroblast growth factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2251 (FGF6)
   04015 Rap1 signaling pathway
    2251 (FGF6)
   04010 MAPK signaling pathway
    2251 (FGF6)
   04151 PI3K-Akt signaling pathway
    2251 (FGF6)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    2251 (FGF6)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2251 (FGF6)
   05226 Gastric cancer
    2251 (FGF6)
   05218 Melanoma
    2251 (FGF6)
   05224 Breast cancer
    2251 (FGF6)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2251 (FGF6)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     2251 (FGF6)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     2251 (FGF6)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     2251 (FGF6)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     2251 (FGF6)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   2251 (FGF6)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   2251 (FGF6)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2251 (FGF6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P10767(Tbio)
UniProt: 
Position
12p13.32
AA seq 208 aa AA seqDB search
MALGQKLFITMSRGAGRLQGTLWALVFLGILVGMVVPSPAGTRANNTLLDSRGWGTLLSR
SRAGLAGEIAGVNWESGYLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTHEENPYSLLEI
STVERGVVSLFGVRSALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYQGTY
IALSKYGRVKRGSKVSPIMTVTHFLPRI
NT seq 627 nt NT seq  +upstreamnt  +downstreamnt
atggccctgggacagaaactgttcatcactatgtcccggggagcaggacgtctgcagggc
acgctgtgggctctcgtcttcctaggcatcctagtgggcatggtggtgccctcgcctgca
ggcacccgtgccaacaacacgctgctggactcgaggggctggggcaccctgctgtccagg
tctcgcgccgggctagctggagagattgccggggtgaactgggaaagtggctatttggtg
gggatcaagcggcagcggaggctctactgcaacgtgggcatcggctttcacctccaggtg
ctccccgacggccggatcagcgggacccacgaggagaacccctacagcctgctggaaatt
tccactgtggagcgaggcgtggtgagtctctttggagtgagaagtgccctcttcgttgcc
atgaacagtaaaggaagattgtacgcaacgcccagcttccaagaagaatgcaagttcaga
gaaaccctcctgcccaacaattacaatgcctacgagtcagacttgtaccaagggacctac
attgccctgagcaaatacggacgggtaaagcggggcagcaaggtgtccccgatcatgact
gtcactcatttccttcccaggatctaa

KEGG   Homo sapiens (human): 2252Help
Entry
2252              CDS       T01001                                 

Gene name
FGF7, HBGF-7, KGF
Definition
(RefSeq) fibroblast growth factor 7
  KO
K04358  
fibroblast growth factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2252 (FGF7)
   04015 Rap1 signaling pathway
    2252 (FGF7)
   04010 MAPK signaling pathway
    2252 (FGF7)
   04151 PI3K-Akt signaling pathway
    2252 (FGF7)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    2252 (FGF7)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2252 (FGF7)
   05226 Gastric cancer
    2252 (FGF7)
   05218 Melanoma
    2252 (FGF7)
   05224 Breast cancer
    2252 (FGF7)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2252 (FGF7)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     2252 (FGF7)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     2252 (FGF7)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     2252 (FGF7)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     2252 (FGF7)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   2252 (FGF7)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   2252 (FGF7)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2252 (FGF7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P21781(Tbio)
UniProt: 
Position
15q21.2
AA seq 194 aa AA seqDB search
MHKWILTWILPTLLYRSCFHIICLVGTISLACNDMTPEQMATNVNCSSPERHTRSYDYME
GGDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESEFYLA
MNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHNGGEMFVALNQKGIPVRGKKTK
KEQKTAHFLPMAIT
NT seq 585 nt NT seq  +upstreamnt  +downstreamnt
atgcacaaatggatactgacatggatcctgccaactttgctctacagatcatgctttcac
attatctgtctagtgggtactatatctttagcttgcaatgacatgactccagagcaaatg
gctacaaatgtgaactgttccagccctgagcgacacacaagaagttatgattacatggaa
ggaggggatataagagtgagaagactcttctgtcgaacacagtggtacctgaggatcgat
aaaagaggcaaagtaaaagggacccaagagatgaagaataattacaatatcatggaaatc
aggacagtggcagttggaattgtggcaatcaaaggggtggaaagtgaattctatcttgca
atgaacaaggaaggaaaactctatgcaaagaaagaatgcaatgaagattgtaacttcaaa
gaactaattctggaaaaccattacaacacatatgcatcagctaaatggacacacaacgga
ggggaaatgtttgttgccttaaatcaaaaggggattcctgtaagaggaaaaaaaacgaag
aaagaacaaaaaacagcccactttcttcctatggcaataacttaa

KEGG   Homo sapiens (human): 2253Help
Entry
2253              CDS       T01001                                 

Gene name
FGF8, AIGF, FGF-8, HBGF-8, HH6, KAL6
Definition
(RefSeq) fibroblast growth factor 8
  KO
K04358  
fibroblast growth factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Disease
H00255  
Hypogonadotropic hypogonadism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2253 (FGF8)
   04015 Rap1 signaling pathway
    2253 (FGF8)
   04010 MAPK signaling pathway
    2253 (FGF8)
   04151 PI3K-Akt signaling pathway
    2253 (FGF8)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    2253 (FGF8)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2253 (FGF8)
   05226 Gastric cancer
    2253 (FGF8)
   05218 Melanoma
    2253 (FGF8)
   05224 Breast cancer
    2253 (FGF8)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2253 (FGF8)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     2253 (FGF8)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     2253 (FGF8)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     2253 (FGF8)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     2253 (FGF8)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   2253 (FGF8)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   2253 (FGF8)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2253 (FGF8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P55075(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
10q24.32
AA seq 233 aa AA seqDB search
MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLV
TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA
ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG
SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
NT seq 702 nt NT seq  +upstreamnt  +downstreamnt
atgggcagcccccgctccgcgctgagctgcctgctgttgcacttgctggtcctctgcctc
caagcccaggaaggcccgggcaggggccctgcgctgggcagggagctcgcttccctgttc
cgggctggccgggagccccagggtgtctcccaacagcatgtgagggagcagagcctggtg
acggatcagctcagccgccgcctcatccggacctaccaactctacagccgcaccagcggg
aagcacgtgcaggtcctggccaacaagcgcatcaacgccatggcagaggacggcgacccc
ttcgcaaagctcatcgtggagacggacacctttggaagcagagttcgagtccgaggagcc
gagacgggcctctacatctgcatgaacaagaaggggaagctgatcgccaagagcaacggc
aaaggcaaggactgcgtcttcacggagattgtgctggagaacaactacacagcgctgcag
aatgccaagtacgagggctggtacatggccttcacccgcaagggccggccccgcaagggc
tccaagacgcggcagcaccagcgtgaggtccacttcatgaagcggctgccccggggccac
cacaccaccgagcagagcctgcgcttcgagttcctcaactacccgcccttcacgcgcagc
ctgcgcggcagccagaggacttgggcccccgagccccgatag

KEGG   Homo sapiens (human): 2254Help
Entry
2254              CDS       T01001                                 

Gene name
FGF9, FGF-9, GAF, HBFG-9, HBGF-9, SYNS3
Definition
(RefSeq) fibroblast growth factor 9
  KO
K04358  
fibroblast growth factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Disease
H00484  
Other brachydactylies
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2254 (FGF9)
   04015 Rap1 signaling pathway
    2254 (FGF9)
   04010 MAPK signaling pathway
    2254 (FGF9)
   04151 PI3K-Akt signaling pathway
    2254 (FGF9)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    2254 (FGF9)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2254 (FGF9)
   05226 Gastric cancer
    2254 (FGF9)
   05218 Melanoma
    2254 (FGF9)
   05224 Breast cancer
    2254 (FGF9)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2254 (FGF9)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     2254 (FGF9)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     2254 (FGF9)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     2254 (FGF9)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     2254 (FGF9)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   2254 (FGF9)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   2254 (FGF9)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2254 (FGF9)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P31371(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
13q12.11
AA seq 208 aa AA seqDB search
MAPLGEVGNYFGVQDAVPFGNVPVLPVDSPVLLSDHLGQSEAGGLPRGPAVTDLDHLKGI
LRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYLGMNE
KGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGTRTKR
HQKFTHFLPRPVDPDKVPELYKDILSQS
NT seq 627 nt NT seq  +upstreamnt  +downstreamnt
atggctcccttaggtgaagttgggaactatttcggtgtgcaggatgcggtaccgtttggg
aatgtgcccgtgttgccggtggacagcccggttttgttaagtgaccacctgggtcagtcc
gaagcaggggggctccccaggggacccgcagtcacggacttggatcatttaaaggggatt
ctcaggcggaggcagctatactgcaggactggatttcacttagaaatcttccccaatggt
actatccagggaaccaggaaagaccacagccgatttggcattctggaatttatcagtata
gcagtgggcctggtcagcattcgaggcgtggacagtggactctacctcgggatgaatgag
aagggggagctgtatggatcagaaaaactaacccaagagtgtgtattcagagaacagttc
gaagaaaactggtataatacgtactcatcaaacctatataagcacgtggacactggaagg
cgatactatgttgcattaaataaagatgggaccccgagagaagggactaggactaaacgg
caccagaaattcacacattttttacctagaccagtggaccccgacaaagtacctgaactg
tataaggatattctaagccaaagttga

KEGG   Homo sapiens (human): 2255Help
Entry
2255              CDS       T01001                                 

Gene name
FGF10
Definition
(RefSeq) fibroblast growth factor 10
  KO
K04358  
fibroblast growth factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Disease
H00642  
Lacrimo-auriculo-dento-digital syndrome (LADD)
H00677  
Aplasia of lacrimal and salivary glands
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2255 (FGF10)
   04015 Rap1 signaling pathway
    2255 (FGF10)
   04010 MAPK signaling pathway
    2255 (FGF10)
   04151 PI3K-Akt signaling pathway
    2255 (FGF10)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    2255 (FGF10)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2255 (FGF10)
   05226 Gastric cancer
    2255 (FGF10)
   05218 Melanoma
    2255 (FGF10)
   05224 Breast cancer
    2255 (FGF10)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2255 (FGF10)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     2255 (FGF10)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     2255 (FGF10)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     2255 (FGF10)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     2255 (FGF10)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   2255 (FGF10)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   2255 (FGF10)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2255 (FGF10)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
O15520(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
5p12
AA seq 208 aa AA seqDB search
MWKWILTHCASAFPHLPGCCCCCFLLLFLVSSVPVTCQALGQDMVSPEATNSSSSSFSSP
SSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGV
VAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVAL
NGKGAPRRGQKTRRKNTSAHFLPMVVHS
NT seq 627 nt NT seq  +upstreamnt  +downstreamnt
atgtggaaatggatactgacacattgtgcctcagcctttccccacctgcccggctgctgc
tgctgctgctttttgttgctgttcttggtgtcttccgtccctgtcacctgccaagccctt
ggtcaggacatggtgtcaccagaggccaccaactcttcttcctcctccttctcctctcct
tccagcgcgggaaggcatgtgcggagctacaatcaccttcaaggagatgtccgctggaga
aagctattctctttcaccaagtactttctcaagattgagaagaacgggaaggtcagcggg
accaagaaggagaactgcccgtacagcatcctggagataacatcagtagaaatcggagtt
gttgccgtcaaagccattaacagcaactattacttagccatgaacaagaaggggaaactc
tatggctcaaaagaatttaacaatgactgtaagctgaaggagaggatagaggaaaatgga
tacaatacctatgcatcatttaactggcagcataatgggaggcaaatgtatgtggcattg
aatggaaaaggagctccaaggagaggacagaaaacacgaaggaaaaacacctctgctcac
tttcttccaatggtggtacactcatag

KEGG   Homo sapiens (human): 2256Help
Entry
2256              CDS       T01001                                 

Gene name
FGF11, FGF-11, FHF-3, FHF3
Definition
(RefSeq) fibroblast growth factor 11
  KO
K22413  
fibroblast growth factor 11/12/13/14
Organism
hsa  Homo sapiens (human)
Brite
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2256 (FGF11)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2256 (FGF11)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q92914(Tdark)
UniProt: 
Position
17p13.1
AA seq 225 aa AA seqDB search
MAALASSLIRQKREVREPGGSRPVSAQRRVCPRGTKSLCQKQLLILLSKVRLCGGRPARP
DRGPEPQLKGIVTKLFCRQGFYLQANPDGSIQGTPEDTSSFTHFNLIPVGLRVVTIQSAK
LGHYMAMNAEGLLYSSPHFTAECRFKECVFENYYVLYASALYRQRRSGRAWYLGLDKEGQ
VMKGNRVKKTKAAAHFLPKLLEVAMYQEPSLHSVPEASPSSPPAP
NT seq 678 nt NT seq  +upstreamnt  +downstreamnt
atggcggcgctggccagtagcctgatccggcagaagcgggaggtccgcgagcccgggggc
agccggccggtgtcggcgcagcggcgcgtgtgtccccgcggcaccaagtccctttgccag
aagcagctcctcatcctgctgtccaaggtgcgactgtgcggggggcggcccgcgcggccg
gaccgcggcccggagcctcagctcaaaggcatcgtcaccaaactgttctgccgccagggt
ttctacctccaggcgaatcccgacggaagcatccagggcaccccagaggataccagctcc
ttcacccacttcaacctgatccctgtgggcctccgtgtggtcaccatccagagcgccaag
ctgggtcactacatggccatgaatgctgagggactgctctacagttcgccgcatttcaca
gctgagtgtcgctttaaggagtgtgtctttgagaattactacgtcctgtacgcctctgct
ctctaccgccagcgtcgttctggccgggcctggtacctcggcctggacaaggagggccag
gtcatgaagggaaaccgagttaagaagaccaaggcagctgcccactttctgcccaagctc
ctggaggtggccatgtaccaggagccttctctccacagtgtccccgaggcctccccttcc
agtccccctgccccctga

KEGG   Homo sapiens (human): 2257Help
Entry
2257              CDS       T01001                                 

Gene name
FGF12, EIEE47, FGF12B, FHF1
Definition
(RefSeq) fibroblast growth factor 12
  KO
K22413  
fibroblast growth factor 11/12/13/14
Organism
hsa  Homo sapiens (human)
Disease
H00606  
Early infantile epileptic encephalopathy
Brite
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2257 (FGF12)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2257 (FGF12)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P61328(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
3q28-q29
AA seq 243 aa AA seqDB search
MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKR
PVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQG
VKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKE
GQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQ
DST
NT seq 732 nt NT seq  +upstreamnt  +downstreamnt
atggctgcggcgatagccagctccttgatccggcagaagcggcaggcgagggagtccaac
agcgaccgagtgtcggcctccaagcgccgctccagccccagcaaagacgggcgctccctg
tgcgagaggcacgtcctcggggtgttcagcaaagtgcgcttctgcagcggccgcaagagg
ccggtgaggcggagaccagaaccccagctcaaagggattgtgacaaggttattcagccag
cagggatacttcctgcagatgcacccagatggtaccattgatgggaccaaggacgaaaac
agcgactacactctcttcaatctaattcccgtgggcctgcgtgtagtggccatccaagga
gtgaaggctagcctctatgtggccatgaatggtgaaggctatctctacagttcagatgtt
ttcactccagaatgcaaattcaaggaatctgtgtttgaaaactactatgtgatctattct
tccacactgtaccgccagcaagaatcaggccgagcttggtttctgggactcaataaagaa
ggtcaaattatgaaggggaacagagtgaagaaaaccaagccctcatcacattttgtaccg
aaacctattgaagtgtgtatgtacagagaaccatcgctacatgaaattggagaaaaacaa
gggcgttcaaggaaaagttctggaacaccaaccatgaatggaggcaaagttgtgaatcaa
gattcaacatag

KEGG   Homo sapiens (human): 2258Help
Entry
2258              CDS       T01001                                 

Gene name
FGF13, FGF-13, FGF2, FHF-2, FHF2
Definition
(RefSeq) fibroblast growth factor 13
  KO
K22413  
fibroblast growth factor 11/12/13/14
Organism
hsa  Homo sapiens (human)
Brite
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2258 (FGF13)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2258 (FGF13)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q92913(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
Xq26.3-q27.1
AA seq 245 aa AA seqDB search
MAAAIASSLIRQKRQAREREKSNACKCVSSPSKGKTSCDKNKLNVFSRVKLFGSKKRRRR
RPEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTK
LYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIM
KGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMS
HNEST
NT seq 738 nt NT seq  +upstreamnt  +downstreamnt
atggcggcggctatcgccagctcgctcatccgtcagaagaggcaagcccgcgagcgcgag
aaatccaacgcctgcaagtgtgtcagcagccccagcaaaggcaagaccagctgcgacaaa
aacaagttaaatgtcttttcccgggtcaaactcttcggctccaagaagaggcgcagaaga
agaccagagcctcagcttaagggtatagttaccaagctatacagccgacaaggctaccac
ttgcagctgcaggcggatggaaccattgatggcaccaaagatgaggacagcacttacact
ctgtttaacctcatccctgtgggtctgcgagtggtggctatccaaggagttcaaaccaag
ctgtacttggcaatgaacagtgagggatacttgtacacctcggaacttttcacacctgag
tgcaaattcaaagaatcagtgtttgaaaattattatgtgacatattcatcaatgatatac
cgtcagcagcagtcaggccgagggtggtatctgggtctgaacaaagaaggagagatcatg
aaaggcaaccatgtgaagaagaacaagcctgcagctcattttctgcctaaaccactgaaa
gtggccatgtacaaggagccatcactgcacgatctcacggagttctcccgatctggaagc
gggaccccaaccaagagcagaagtgtctctggcgtgctgaacggaggcaaatccatgagc
cacaatgaatcaacgtag

KEGG   Homo sapiens (human): 2259Help
Entry
2259              CDS       T01001                                 

Gene name
FGF14, FGF-14, FHF-4, FHF4, SCA27
Definition
(RefSeq) fibroblast growth factor 14
  KO
K22413  
fibroblast growth factor 11/12/13/14
Organism
hsa  Homo sapiens (human)
Disease
H00063  
Spinocerebellar ataxia (SCA)
Brite
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   2259 (FGF14)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   2259 (FGF14)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q92915(Tbio)
UniProt: 
Position
13q33.1
AA seq 247 aa AA seqDB search
MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRR
LRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK
TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ
AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP
VNKSKTT
NT seq 744 nt NT seq  +upstreamnt  +downstreamnt
atggccgcggccatcgctagcggcttgatccgccagaagcggcaggcgcgggagcagcac
tgggaccggccgtctgccagcaggaggcggagcagccccagcaagaaccgcgggctctgc
aacggcaacctggtggatatcttctccaaagtgcgcatcttcggcctcaagaagcgcagg
ttgcggcgccaagatccccagctcaagggtatagtgaccaggttatattgcaggcaaggc
tactacttgcaaatgcaccccgatggagctctcgatggaaccaaggatgacagcactaat
tctacactcttcaacctcataccagtgggactacgtgttgttgccatccagggagtgaaa
acagggttgtatatagccatgaatggagaaggttacctctacccatcagaactttttacc
cctgaatgcaagtttaaagaatctgtttttgaaaattattatgtaatctactcatccatg
ttgtacagacaacaggaatctggtagagcctggtttttgggattaaataaggaagggcaa
gctatgaaagggaacagagtaaagaaaaccaaaccagcagctcattttctacccaagcca
ttggaagttgccatgtaccgagaaccatctttgcatgatgttggggaaacggtcccgaag
cctggggtgacgccaagtaaaagcacaagtgcgtctgcaataatgaatggaggcaaacca
gtcaacaagagtaagacaacatag

KEGG   Homo sapiens (human): 2277Help
Entry
2277              CDS       T01001                                 

Gene name
VEGFD, FIGF, VEGF-D
Definition
(RefSeq) vascular endothelial growth factor D
  KO
K05449  
vascular endothelial growth factor C/D
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Focal adhesion
Relaxin signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Pathways in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2277 (VEGFD)
   04015 Rap1 signaling pathway
    2277 (VEGFD)
   04010 MAPK signaling pathway
    2277 (VEGFD)
   04151 PI3K-Akt signaling pathway
    2277 (VEGFD)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    2277 (VEGFD)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    2277 (VEGFD)
 Organismal Systems
  Endocrine system
   04926 Relaxin signaling pathway
    2277 (VEGFD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2277 (VEGFD)
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    2277 (VEGFD)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass I
    2277 (VEGFD)
Cell adhesion molecules and their ligands [BR:hsa04516]
 2. Integrin Family
  Beta1 integrins
   VLA-9
    ITGB1; integrin beta 1 [KO:K05719]
     2277 (VEGFD)
 7. Others
  NRP1; neuropilin 1 [KO:K06724]
   2277 (VEGFD)
  NRP2; neuropilin 2 [KO:K06819]
   2277 (VEGFD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
O43915(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
Xp22.2
AA seq 354 aa AA seqDB search
MYREWVVVNVFMMLYVQLVQGSSNEHGPVKRSSQSTLERSEQQIRAASSLEELLRITHSE
DWKLWRCRLRLKSFTSMDSRSASHRSTRFAATFYDIETLKVIDEEWQRTQCSPRETCVEV
ASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPELVP
VKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPIDMLWDSNKCKCVLQEE
NPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNCSCFECKESLETC
CQKHKLFHPDTCSCEDRCPFHTRPCASGKTACAKHCRFPKEKRAAQGPHSRKNP
NT seq 1065 nt NT seq  +upstreamnt  +downstreamnt
atgtacagagagtgggtagtggtgaatgttttcatgatgttgtacgtccagctggtgcag
ggctccagtaatgaacatggaccagtgaagcgatcatctcagtccacattggaacgatct
gaacagcagatcagggctgcttctagtttggaggaactacttcgaattactcactctgag
gactggaagctgtggagatgcaggctgaggctcaaaagttttaccagtatggactctcgc
tcagcatcccatcggtccactaggtttgcggcaactttctatgacattgaaacactaaaa
gttatagatgaagaatggcaaagaactcagtgcagccctagagaaacgtgcgtggaggtg
gccagtgagctggggaagagtaccaacacattcttcaagcccccttgtgtgaacgtgttc
cgatgtggtggctgttgcaatgaagagagccttatctgtatgaacaccagcacctcgtac
atttccaaacagctctttgagatatcagtgcctttgacatcagtacctgaattagtgcct
gttaaagttgccaatcatacaggttgtaagtgcttgccaacagccccccgccatccatac
tcaattatcagaagatccatccagatccctgaagaagatcgctgttcccattccaagaaa
ctctgtcctattgacatgctatgggatagcaacaaatgtaaatgtgttttgcaggaggaa
aatccacttgctggaacagaagaccactctcatctccaggaaccagctctctgtgggcca
cacatgatgtttgacgaagatcgttgcgagtgtgtctgtaaaacaccatgtcccaaagat
ctaatccagcaccccaaaaactgcagttgctttgagtgcaaagaaagtctggagacctgc
tgccagaagcacaagctatttcacccagacacctgcagctgtgaggacagatgccccttt
cataccagaccatgtgcaagtggcaaaacagcatgtgcaaagcattgccgctttccaaag
gagaaaagggctgcccaggggccccacagccgaaagaatccttga

KEGG   Homo sapiens (human): 2323Help
Entry
2323              CDS       T01001                                 

Gene name
FLT3LG, FL, FLG3L, FLT3L
Definition
(RefSeq) fms related tyrosine kinase 3 ligand
  KO
K05454  
fms-related tyrosine kinase 3 ligand
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Hematopoietic cell lineage
Pathways in cancer
Network
N00217  
FLT3LG-FLT3-RAS-ERK signaling pathway
N00218  
FLT3LG-FLT3-RAS-PI3K signaling pathway
N00219  
FLT3LG-FLT3-STAT5 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2323 (FLT3LG)
   04010 MAPK signaling pathway
    2323 (FLT3LG)
   04151 PI3K-Akt signaling pathway
    2323 (FLT3LG)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    2323 (FLT3LG)
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    2323 (FLT3LG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2323 (FLT3LG)
Cytokines [BR:hsa04052]
 PDGF family
  4-Helix bundle growth factors
   2323 (FLT3LG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P49771(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
19q13.33
AA seq 235 aa AA seqDB search
MTVLAPAWSPTTYLLLLLLLSSGLSGTQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTV
ASNLQDEELCGGLWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCL
RFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEATAPT
APQPPLLLLLLLPVGLLLLAAAWCLHWQRTRRRTPRPGEQVPPVPSPQDLLLVEH
NT seq 708 nt NT seq  +upstreamnt  +downstreamnt
atgacagtgctggcgccagcctggagcccaacaacctatctcctcctgctgctgctgctg
agctcgggactcagtgggacccaggactgctccttccaacacagccccatctcctccgac
ttcgctgtcaaaatccgtgagctgtctgactacctgcttcaagattacccagtcaccgtg
gcctccaacctgcaggacgaggagctctgcgggggcctctggcggctggtcctggcacag
cgctggatggagcggctcaagactgtcgctgggtccaagatgcaaggcttgctggagcgc
gtgaacacggagatacactttgtcaccaaatgtgcctttcagcccccccccagctgtctt
cgcttcgtccagaccaacatctcccgcctcctgcaggagacctccgagcagctggtggcg
ctgaagccctggatcactcgccagaacttctcccggtgcctggagctgcagtgtcagccc
gactcctcaaccctgccacccccatggagtccccggcccctggaggccacagccccgaca
gccccgcagccccctctgctcctcctactgctgctgcccgtgggcctcctgctgctggcc
gctgcctggtgcctgcactggcagaggacgcggcggaggacaccccgccctggggagcag
gtgccccccgtccccagtccccaggacctgctgcttgtggagcactga

KEGG   Homo sapiens (human): 26281Help
Entry
26281             CDS       T01001                                 

Gene name
FGF20, FGF-20, RHDA2
Definition
(RefSeq) fibroblast growth factor 20
  KO
K04358  
fibroblast growth factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Disease
H01728  
Potter syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    26281 (FGF20)
   04015 Rap1 signaling pathway
    26281 (FGF20)
   04010 MAPK signaling pathway
    26281 (FGF20)
   04151 PI3K-Akt signaling pathway
    26281 (FGF20)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    26281 (FGF20)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    26281 (FGF20)
   05226 Gastric cancer
    26281 (FGF20)
   05218 Melanoma
    26281 (FGF20)
   05224 Breast cancer
    26281 (FGF20)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   26281 (FGF20)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     26281 (FGF20)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     26281 (FGF20)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     26281 (FGF20)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     26281 (FGF20)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   26281 (FGF20)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   26281 (FGF20)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   26281 (FGF20)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q9NP95(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
8p22
AA seq 211 aa AA seqDB search
MAPLAEVGGFLGGLEGLGQQVGSHFLLPPAGERPPLLGERRSAAERSARGGPGAAQLAHL
HGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYLG
MNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGAR
SKRHQKFTHFLPRPVDPERVPELYKDLLMYT
NT seq 636 nt NT seq  +upstreamnt  +downstreamnt
atggctcccttagccgaagtcgggggctttctgggcggcctggagggcttgggccagcag
gtgggttcgcatttcctgttgcctcctgccggggagcggccgccgctgctgggcgagcgc
aggagcgcggcggagcggagcgcgcgcggcgggccgggggctgcgcagctggcgcacctg
cacggcatcctgcgccgccggcagctctattgccgcaccggcttccacctgcagatcctg
cccgacggcagcgtgcagggcacccggcaggaccacagcctcttcggtatcttggaattc
atcagtgtggcagtgggactggtcagtattagaggtgtggacagtggtctctatcttgga
atgaatgacaaaggagaactctatggatcagagaaacttacttccgaatgcatctttagg
gagcagtttgaagagaactggtataacacctattcatctaacatatataaacatggagac
actggccgcaggtattttgtggcacttaacaaagacggaactccaagagatggcgccagg
tccaagaggcatcagaaatttacacatttcttacctagaccagtggatccagaaagagtt
ccagaattgtacaaggacctactgatgtacacttga

KEGG   Homo sapiens (human): 26291Help
Entry
26291             CDS       T01001                                 

Gene name
FGF21
Definition
(RefSeq) fibroblast growth factor 21
  KO
K22429  
fibroblast growth factor 21
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Thermogenesis
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    26291 (FGF21)
   04015 Rap1 signaling pathway
    26291 (FGF21)
   04010 MAPK signaling pathway
    26291 (FGF21)
   04151 PI3K-Akt signaling pathway
    26291 (FGF21)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    26291 (FGF21)
 Organismal Systems
  Environmental adaptation
   04714 Thermogenesis
    26291 (FGF21)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    26291 (FGF21)
   05226 Gastric cancer
    26291 (FGF21)
   05218 Melanoma
    26291 (FGF21)
   05224 Breast cancer
    26291 (FGF21)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   26291 (FGF21)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     26291 (FGF21)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     26291 (FGF21)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     26291 (FGF21)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     26291 (FGF21)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   26291 (FGF21)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q9NSA1(Tbio)
UniProt: 
Position
19q13.33
AA seq 209 aa AA seqDB search
MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAH
LEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEA
CSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGI
LAPQPPDVGSSDPLSMVGPSQGRSPSYAS
NT seq 630 nt NT seq  +upstreamnt  +downstreamnt
atggactcggacgagaccgggttcgagcactcaggactgtgggtttctgtgctggctggt
cttctgctgggagcctgccaggcacaccccatccctgactccagtcctctcctgcaattc
gggggccaagtccggcagcggtacctctacacagatgatgcccagcagacagaagcccac
ctggagatcagggaggatgggacggtggggggcgctgctgaccagagccccgaaagtctc
ctgcagctgaaagccttgaagccgggagttattcaaatcttgggagtcaagacatccagg
ttcctgtgccagcggccagatggggccctgtatggatcgctccactttgaccctgaggcc
tgcagcttccgggagctgcttcttgaggacggatacaatgtttaccagtccgaagcccac
ggcctcccgctgcacctgccagggaacaagtccccacaccgggaccctgcaccccgagga
ccagctcgcttcctgccactaccaggcctgccccccgcactcccggagccacccggaatc
ctggccccccagccccccgatgtgggctcctcggaccctctgagcatggtgggaccttcc
cagggccgaagccccagctacgcttcctga

KEGG   Homo sapiens (human): 27006Help
Entry
27006             CDS       T01001                                 

Gene name
FGF22
Definition
(RefSeq) fibroblast growth factor 22
  KO
K04358  
fibroblast growth factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Melanoma
Breast cancer
Gastric cancer
Network
N00019  
FGF-FGFR-RAS-ERK signaling pathway
N00037  
FGF-FGFR-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    27006 (FGF22)
   04015 Rap1 signaling pathway
    27006 (FGF22)
   04010 MAPK signaling pathway
    27006 (FGF22)
   04151 PI3K-Akt signaling pathway
    27006 (FGF22)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    27006 (FGF22)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    27006 (FGF22)
   05226 Gastric cancer
    27006 (FGF22)
   05218 Melanoma
    27006 (FGF22)
   05224 Breast cancer
    27006 (FGF22)
Cytokines [BR:hsa04052]
 PDGF family
  Beta-trefoil growth factors
   27006 (FGF22)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    FGFR1; fibroblast growth factor receptor 1 [KO:K04362]
     27006 (FGF22)
    FGFR2; fibroblast growth factor receptor 2 [KO:K05093]
     27006 (FGF22)
    FGFR3; fibroblast growth factor receptor [KO:K05094]
     27006 (FGF22)
    FGFR4; fibroblast growth factor receptor 4 [KO:K05095]
     27006 (FGF22)
 6. Sialomucin Family
  GLG1, ESL1; golgi apparatus protein 1 [KO:K06816]
   27006 (FGF22)
 7. Others
  SDC4; syndecan 4 [KO:K16338]
   27006 (FGF22)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   27006 (FGF22)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q9HCT0(Tbio)
UniProt: 
Position
19p13.3
AA seq 170 aa AA seqDB search
MRRRLWLGLAWLLLARAPDAAGTPSASRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGR
VQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIE
ENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS
NT seq 513 nt NT seq  +upstreamnt  +downstreamnt
atgcgccgccgcctgtggctgggcctggcctggctgctgctggcgcgggcgccggacgcc
gcgggaaccccgagcgcgtcgcggggaccgcgcagctacccgcacctggagggcgacgtg
cgctggcggcgcctcttctcctccactcacttcttcctgcgcgtggatcccggcggccgc
gtgcagggcacccgctggcgccacggccaggacagcatcctggagatccgctctgtacac
gtgggcgtcgtggtcatcaaagcagtgtcctcaggcttctacgtggccatgaaccgccgg
ggccgcctctacgggtcgcgactctacaccgtggactgcaggttccgggagcgcatcgaa
gagaacggccacaacacctacgcctcacagcgctggcgccgccgcggccagcccatgttc
ctggcgctggacaggaggggggggccccggccaggcggccggacgcggcggtaccacctg
tccgcccacttcctgcccgtcctggtctcctga

KEGG   Homo sapiens (human): 284Help
Entry
284               CDS       T01001                                 

Gene name
ANGPT1, AGP1, AGPT, ANG1
Definition
(RefSeq) angiopoietin 1
  KO
K05465  
angiopoietin 1
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
HIF-1 signaling pathway
PI3K-Akt signaling pathway
Rheumatoid arthritis
Drug target
Trebananib: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    284 (ANGPT1)
   04015 Rap1 signaling pathway
    284 (ANGPT1)
   04010 MAPK signaling pathway
    284 (ANGPT1)
   04066 HIF-1 signaling pathway
    284 (ANGPT1)
   04151 PI3K-Akt signaling pathway
    284 (ANGPT1)
 Human Diseases
  Immune diseases
   05323 Rheumatoid arthritis
    284 (ANGPT1)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   284 (ANGPT1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q15389(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
8q23.1
AA seq 498 aa AA seqDB search
MTVFLSFAFLAAILTHIGCSNQRRSPENSGRRYNRIQHGQCAYTFILPEHDGNCRESTTD
QYNTNALQRDAPHVEPDFSSQKLQHLEHVMENYTQWLQKLENYIVENMKSEMAQIQQNAV
QNHTATMLEIGTSLLSQTAEQTRKLTDVETQVLNQTSRLEIQLLENSLSTYKLEKQLLQQ
TNEILKIHEKNSLLEHKILEMEGKHKEELDTLKEEKENLQGLVTRQTYIIQELEKQLNRA
TTNNSVLQKQQLELMDTVHNLVNLCTKEGVLLKGGKREEEKPFRDCADVYQAGFNKSGIY
TIYINNMPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNE
FIFAITSQRQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGKQSSLIL
HGADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYFK
GPSYSLRSTTMMIRPLDF
NT seq 1497 nt NT seq  +upstreamnt  +downstreamnt
atgacagttttcctttcctttgctttcctcgctgccattctgactcacatagggtgcagc
aatcagcgccgaagtccagaaaacagtgggagaagatataaccggattcaacatgggcaa
tgtgcctacactttcattcttccagaacacgatggcaactgtcgtgagagtacgacagac
cagtacaacacaaacgctctgcagagagatgctccacacgtggaaccggatttctcttcc
cagaaacttcaacatctggaacatgtgatggaaaattatactcagtggctgcaaaaactt
gagaattacattgtggaaaacatgaagtcggagatggcccagatacagcagaatgcagtt
cagaaccacacggctaccatgctggagataggaaccagcctcctctctcagactgcagag
cagaccagaaagctgacagatgttgagacccaggtactaaatcaaacttctcgacttgag
atacagctgctggagaattcattatccacctacaagctagagaagcaacttcttcaacag
acaaatgaaatcttgaagatccatgaaaaaaacagtttattagaacataaaatcttagaa
atggaaggaaaacacaaggaagagttggacaccttaaaggaagagaaagagaaccttcaa
ggcttggttactcgtcaaacatatataatccaggagctggaaaagcaattaaacagagct
accaccaacaacagtgtccttcagaagcagcaactggagctgatggacacagtccacaac
cttgtcaatctttgcactaaagaaggtgttttactaaagggaggaaaaagagaggaagag
aaaccatttagagactgtgcagatgtatatcaagctggttttaataaaagtggaatctac
actatttatattaataatatgccagaacccaaaaaggtgttttgcaatatggatgtcaat
gggggaggttggactgtaatacaacatcgtgaagatggaagtctagatttccaaagaggc
tggaaggaatataaaatgggttttggaaatccctccggtgaatattggctggggaatgag
tttatttttgccattaccagtcagaggcagtacatgctaagaattgagttaatggactgg
gaagggaaccgagcctattcacagtatgacagattccacataggaaatgaaaagcaaaac
tataggttgtatttaaaaggtcacactgggacagcaggaaaacagagcagcctgatctta
cacggtgctgatttcagcactaaagatgctgataatgacaactgtatgtgcaaatgtgcc
ctcatgttaacaggaggatggtggtttgatgcttgtggcccctccaatctaaatggaatg
ttctatactgcgggacaaaaccatggaaaactgaatgggataaagtggcactacttcaaa
gggcccagttactccttacgttccacaactatgatgattcgacctttagatttttga

KEGG   Homo sapiens (human): 285Help
Entry
285               CDS       T01001                                 

Gene name
ANGPT2, AGPT2, ANG2
Definition
(RefSeq) angiopoietin 2
  KO
K05466  
angiopoietin 2
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
HIF-1 signaling pathway
PI3K-Akt signaling pathway
Kaposi's sarcoma-associated herpesvirus infection
Network
N00157  
KSHV vGPCR to GNB/G-ERK signaling pathway
Drug target
Nesvacumab: 
Trebananib: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    285 (ANGPT2)
   04015 Rap1 signaling pathway
    285 (ANGPT2)
   04010 MAPK signaling pathway
    285 (ANGPT2)
   04066 HIF-1 signaling pathway
    285 (ANGPT2)
   04151 PI3K-Akt signaling pathway
    285 (ANGPT2)
 Human Diseases
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    285 (ANGPT2)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   285 (ANGPT2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
O15123(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
8p23.1
AA seq 496 aa AA seqDB search
MWQIVFFTLSCDLVLAAAYNNFRKSMDSIGKKQYQVQHGSCSYTFLLPEMDNCRSSSSPY
VSNAVQRDAPLEYDDSVQRLQVLENIMENNTQWLMKLENYIQDNMKKEMVEIQQNAVQNQ
TAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQLLEHSLSTNKLEKQILDQTSE
INKLQDKNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQNSIIEELEKKIVTATVN
NSVLQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTL
TFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFV
SQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPG
NDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGS
GYSLKATTMMIRPADF
NT seq 1491 nt NT seq  +upstreamnt  +downstreamnt
atgtggcagattgttttctttactctgagctgtgatcttgtcttggccgcagcctataac
aactttcggaagagcatggacagcataggaaagaagcaatatcaggtccagcatgggtcc
tgcagctacactttcctcctgccagagatggacaactgccgctcttcctccagcccctac
gtgtccaatgctgtgcagagggacgcgccgctcgaatacgatgactcggtgcagaggctg
caagtgctggagaacatcatggaaaacaacactcagtggctaatgaagcttgagaattat
atccaggacaacatgaagaaagaaatggtagagatacagcagaatgcagtacagaaccag
acggctgtgatgatagaaatagggacaaacctgttgaaccaaacagcggagcaaacgcgg
aagttaactgatgtggaagcccaagtattaaatcagaccacgagacttgaacttcagctc
ttggaacactccctctcgacaaacaaattggaaaaacagattttggaccagaccagtgaa
ataaacaaattgcaagataagaacagtttcctagaaaagaaggtgctagctatggaagac
aagcacatcatccaactacagtcaataaaagaagagaaagatcagctacaggtgttagta
tccaagcaaaattccatcattgaagaactagaaaaaaaaatagtgactgccacggtgaat
aattcagttcttcagaagcagcaacatgatctcatggagacagttaataacttactgact
atgatgtccacatcaaactcagctaaggaccccactgttgctaaagaagaacaaatcagc
ttcagagactgtgctgaagtattcaaatcaggacacaccacgaatggcatctacacgtta
acattccctaattctacagaagagatcaaggcctactgtgacatggaagctggaggaggc
gggtggacaattattcagcgacgtgaggatggcagcgttgattttcagaggacttggaaa
gaatataaagtgggatttggtaacccttcaggagaatattggctgggaaatgagtttgtt
tcgcaactgactaatcagcaacgctatgtgcttaaaatacaccttaaagactgggaaggg
aatgaggcttactcattgtatgaacatttctatctctcaagtgaagaactcaattatagg
attcaccttaaaggacttacagggacagccggcaaaataagcagcatcagccaaccagga
aatgattttagcacaaaggatggagacaacgacaaatgtatttgcaaatgttcacaaatg
ctaacaggaggctggtggtttgatgcatgtggtccttccaacttgaacggaatgtactat
ccacagaggcagaacacaaataagttcaacggcattaaatggtactactggaaaggctca
ggctattcgctcaaggccacaaccatgatgatccgaccagcagatttctaa

KEGG   Homo sapiens (human): 3082Help
Entry
3082              CDS       T01001                                 

Gene name
HGF, DFNB39, F-TCF, HGFB, HPTA, SF
Definition
(RefSeq) hepatocyte growth factor
  KO
K05460  
hepatocyte growth factor
Organism
hsa  Homo sapiens (human)
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Focal adhesion
Malaria
Pathways in cancer
Proteoglycans in cancer
Renal cell carcinoma
Melanoma
Hepatocellular carcinoma
Gastric cancer
Network
N00043  
HGF-MET-PI3K signaling pathway
N00216  
HGF-MET-RAS-ERK signaling pathway
N00246  
HGF-overexpression to RAS-ERK signaling pathway
N00247  
HGF-overexpression to PI3K signaling pathway
Disease
H00048  
Hepatocellular carcinoma
H00605  
Deafness, autosomal recessive
Drug target
Ficlatuzumab: 
Rilotumumab: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    3082 (HGF)
   04015 Rap1 signaling pathway
    3082 (HGF)
   04010 MAPK signaling pathway
    3082 (HGF)
   04151 PI3K-Akt signaling pathway
    3082 (HGF)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    3082 (HGF)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    3082 (HGF)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    3082 (HGF)
   05205 Proteoglycans in cancer
    3082 (HGF)
   05225 Hepatocellular carcinoma
    3082 (HGF)
   05226 Gastric cancer
    3082 (HGF)
   05218 Melanoma
    3082 (HGF)
   05211 Renal cell carcinoma
    3082 (HGF)
  Infectious diseases
   05144 Malaria
    3082 (HGF)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    3082 (HGF)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   3082 (HGF)
Cell adhesion molecules and their ligands [BR:hsa04516]
 7. Others
  SDC1; syndecan 1 [KO:K06257]
   3082 (HGF)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   3082 (HGF)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P14210(Tchem)
UniProt: 
Structure
PDB: 

Jmol
Position
7q21.11
AA seq 728 aa AA seqDB search
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPL
ETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGS
ESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNME
DLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNL
DHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRD
LKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLP
NYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAG
AEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII
LTYKVPQS
NT seq 2187 nt NT seq  +upstreamnt  +downstreamnt
atgtgggtgaccaaactcctgccagccctgctgctgcagcatgtcctcctgcatctcctc
ctgctccccatcgccatcccctatgcagagggacaaaggaaaagaagaaatacaattcat
gaattcaaaaaatcagcaaagactaccctaatcaaaatagatccagcactgaagataaaa
accaaaaaagtgaatactgcagaccaatgtgctaatagatgtactaggaataaaggactt
ccattcacttgcaaggcttttgtttttgataaagcaagaaaacaatgcctctggttcccc
ttcaatagcatgtcaagtggagtgaaaaaagaatttggccatgaatttgacctctatgaa
aacaaagactacattagaaactgcatcattggtaaaggacgcagctacaagggaacagta
tctatcactaagagtggcatcaaatgtcagccctggagttccatgataccacacgaacac
agctttttgccttcgagctatcggggtaaagacctacaggaaaactactgtcgaaatcct
cgaggggaagaagggggaccctggtgtttcacaagcaatccagaggtacgctacgaagtc
tgtgacattcctcagtgttcagaagttgaatgcatgacctgcaatggggagagttatcga
ggtctcatggatcatacagaatcaggcaagatttgtcagcgctgggatcatcagacacca
caccggcacaaattcttgcctgaaagatatcccgacaagggctttgatgataattattgc
cgcaatcccgatggccagccgaggccatggtgctatactcttgaccctcacacccgctgg
gagtactgtgcaattaaaacatgcgctgacaatactatgaatgacactgatgttcctttg
gaaacaactgaatgcatccaaggtcaaggagaaggctacaggggcactgtcaataccatt
tggaatggaattccatgtcagcgttgggattctcagtatcctcacgagcatgacatgact
cctgaaaatttcaagtgcaaggacctacgagaaaattactgccgaaatccagatgggtct
gaatcaccctggtgttttaccactgatccaaacatccgagttggctactgctcccaaatt
ccaaactgtgatatgtcacatggacaagattgttatcgtgggaatggcaaaaattatatg
ggcaacttatcccaaacaagatctggactaacatgttcaatgtgggacaagaacatggaa
gacttacatcgtcatatcttctgggaaccagatgcaagtaagctgaatgagaattactgc
cgaaatccagatgatgatgctcatggaccctggtgctacacgggaaatccactcattcct
tgggattattgccctatttctcgttgtgaaggtgataccacacctacaatagtcaattta
gaccatcccgtaatatcttgtgccaaaacgaaacaattgcgagttgtaaatgggattcca
acacgaacaaacataggatggatggttagtttgagatacagaaataaacatatctgcgga
ggatcattgataaaggagagttgggttcttactgcacgacagtgtttcccttctcgagac
ttgaaagattatgaagcttggcttggaattcatgatgtccacggaagaggagatgagaaa
tgcaaacaggttctcaatgtttcccagctggtatatggccctgaaggatcagatctggtt
ttaatgaagcttgccaggcctgctgtcctggatgattttgttagtacgattgatttacct
aattatggatgcacaattcctgaaaagaccagttgcagtgtttatggctggggctacact
ggattgatcaactatgatggcctattacgagtggcacatctctatataatgggaaatgag
aaatgcagccagcatcatcgagggaaggtgactctgaatgagtctgaaatatgtgctggg
gctgaaaagattggatcaggaccatgtgagggggattatggtggcccacttgtttgtgag
caacataaaatgagaatggttcttggtgtcattgttcctggtcgtggatgtgccattcca
aatcgtcctggtatttttgtccgagtagcatattatgcaaaatggatacacaaaattatt
ttaacatataaggtaccacagtcatag

KEGG   Homo sapiens (human): 3479Help
Entry
3479              CDS       T01001                                 

Gene name
IGF1, IGF-I, IGFI, MGF
Definition
(RefSeq) insulin like growth factor 1
  KO
K05459  
insulin-like growth factor 1
Organism
hsa  Homo sapiens (human)
Pathway
EGFR tyrosine kinase inhibitor resistance
Endocrine resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Oocyte meiosis
p53 signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Long-term depression
Inflammatory mediator regulation of TRP channels
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Aldosterone-regulated sodium reabsorption
Pathways in cancer
Transcriptional misregulation in cancer
Proteoglycans in cancer
Glioma
Prostate cancer
Melanoma
Breast cancer
Hypertrophic cardiomyopathy (HCM)
Dilated cardiomyopathy (DCM)
Network
N00133  
EWSR1-FLI1 fusion to transcriptional activation
N00135  
EWSR1-ERG fusion to transcriptional activation
N00182  
IGF-IGFR-PI3K-NFKB signaling pathway
Disease
H00015  
Malignant pleural mesothelioma
H02040  
Insulin-like growth factor I deficiency
Drug target
Masoprocol: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    3479 (IGF1)
   04015 Rap1 signaling pathway
    3479 (IGF1)
   04010 MAPK signaling pathway
    3479 (IGF1)
   04066 HIF-1 signaling pathway
    3479 (IGF1)
   04068 FoxO signaling pathway
    3479 (IGF1)
   04151 PI3K-Akt signaling pathway
    3479 (IGF1)
   04152 AMPK signaling pathway
    3479 (IGF1)
   04150 mTOR signaling pathway
    3479 (IGF1)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    3479 (IGF1)
   04115 p53 signaling pathway
    3479 (IGF1)
  Cellular community - eukaryotes
   04510 Focal adhesion
    3479 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    3479 (IGF1)
 Organismal Systems
  Endocrine system
   04913 Ovarian Steroidogenesis
    3479 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    3479 (IGF1)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    3479 (IGF1)
  Nervous system
   04730 Long-term depression
    3479 (IGF1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    3479 (IGF1)
  Aging
   04211 Longevity regulating pathway - mammal
    3479 (IGF1)
   04213 Longevity regulating pathway - multiple species
    3479 (IGF1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    3479 (IGF1)
   05202 Transcriptional misregulation in cancers
    3479 (IGF1)
   05205 Proteoglycans in cancer
    3479 (IGF1)
   05214 Glioma
    3479 (IGF1)
   05218 Melanoma
    3479 (IGF1)
   05215 Prostate cancer
    3479 (IGF1)
   05224 Breast cancer
    3479 (IGF1)
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    3479 (IGF1)
   05414 Dilated cardiomyopathy (DCM)
    3479 (IGF1)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    3479 (IGF1)
   01522 Endocrine resistance
    3479 (IGF1)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   3479 (IGF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P05019(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
12q23.2
AA seq 195 aa AA seqDB search
MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKTQKYQPPSTNKNTKSQRRKGWPKTHPGGEQKEGTEASLQIRGKKKEQRR
EIGSRNAECRGKKGK
NT seq 588 nt NT seq  +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtgaagatgcacaccatgtcctcctcgcatctcttctacctggcgctgtgcctgctc
accttcaccagctctgccacggctggaccggagacgctctgcggggctgagctggtggat
gctcttcagttcgtgtgtggagacaggggcttttatttcaacaagcccacagggtatggc
tccagcagtcggagggcgcctcagacaggcatcgtggatgagtgctgcttccggagctgt
gatctaaggaggctggagatgtattgcgcacccctcaagcctgccaagtcagctcgctct
gtccgtgcccagcgccacaccgacatgcccaagacccagaagtatcagcccccatctacc
aacaagaacacgaagtctcagagaaggaaaggttggccaaagacacatccaggaggggaa
cagaaggaggggacagaagcaagtctgcagatcagaggaaagaagaaagagcagaggagg
gagattggaagtagaaatgctgaatgcagaggcaaaaaaggaaaatga

KEGG   Homo sapiens (human): 3481Help
Entry
3481              CDS       T01001                                 

Gene name
IGF2, C11orf43, GRDF, IGF-II, PP9974
Definition
(RefSeq) insulin like growth factor 2
  KO
K13769  
insulin-like growth factor 2
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
PI3K-Akt signaling pathway
Pathways in cancer
Proteoglycans in cancer
Hepatocellular carcinoma
Network
N00233  
IGF2-IGF1R-RAS-ERK signaling pathway
N00234  
IGF2-IGF1R-PI3K signaling pathway
N00235  
IGF2-overexpression to RAS-ERK signaling pathway
N00236  
IGF2-overexpression to PI3K signaling pathway
N00237  
IGF1R-overexpression to RAS-ERK signaling pathway
N00238  
IGF1R-overexpression to PI3K signaling pathway
Disease
H00033  
Adrenal carcinoma
H00048  
Hepatocellular carcinoma
H00711  
Russell-Silver syndrome
H00713  
Beckwith-Wiedemann syndrome
Drug target
Dusigitumab: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    3481 (IGF2)
   04010 MAPK signaling pathway
    3481 (IGF2)
   04151 PI3K-Akt signaling pathway
    3481 (IGF2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    3481 (IGF2)
   05205 Proteoglycans in cancer
    3481 (IGF2)
   05225 Hepatocellular carcinoma
    3481 (IGF2)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   3481 (IGF2)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   3481 (IGF2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P01344(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
11p15.5
AA seq 180 aa AA seqDB search
MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
NT seq 543 nt NT seq  +upstreamnt  +downstreamnt
atgggaatcccaatggggaagtcgatgctggtgcttctcaccttcttggccttcgcctcg
tgctgcattgctgcttaccgccccagtgagaccctgtgcggcggggagctggtggacacc
ctccagttcgtctgtggggaccgcggcttctacttcagcaggcccgcaagccgtgtgagc
cgtcgcagccgtggcatcgttgaggagtgctgtttccgcagctgtgacctggccctcctg
gagacgtactgtgctacccccgccaagtccgagagggacgtgtcgacccctccgaccgtg
cttccggacaacttccccagataccccgtgggcaagttcttccaatatgacacctggaag
cagtccacccagcgcctgcgcaggggcctgcctgccctcctgcgtgcccgccggggtcac
gtgctcgccaaggagctcgaggcgttcagggaggccaaacgtcaccgtcccctgattgct
ctacccacccaagaccccgcccacgggggcgcccccccagagatggccagcaatcggaag
tga

KEGG   Homo sapiens (human): 3630Help
Entry
3630              CDS       T01001                                 

Gene name
INS, IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10
Definition
(RefSeq) insulin
  KO
K04526  
insulin
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
Oocyte meiosis
Autophagy - animal
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Regulation of actin cytoskeleton
Insulin signaling pathway
Insulin secretion
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Type I diabetes mellitus
Maturity onset diabetes of the young
Aldosterone-regulated sodium reabsorption
Prostate cancer
Disease
H00408  
Type I diabetes mellitus
H00410  
Maturity onset diabetes of the young (MODY)
H00512  
Permanent neonatal diabetes mellitus (PNDM)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    3630 (INS)
   04015 Rap1 signaling pathway
    3630 (INS)
   04010 MAPK signaling pathway
    3630 (INS)
   04066 HIF-1 signaling pathway
    3630 (INS)
   04068 FoxO signaling pathway
    3630 (INS)
   04072 Phospholipase D signaling pathway
    3630 (INS)
   04022 cGMP - PKG signaling pathway
    3630 (INS)
   04151 PI3K-Akt signaling pathway
    3630 (INS)
   04152 AMPK signaling pathway
    3630 (INS)
   04150 mTOR signaling pathway
    3630 (INS)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    3630 (INS)
  Cell growth and death
   04114 Oocyte meiosis
    3630 (INS)
  Cell motility
   04810 Regulation of actin cytoskeleton
    3630 (INS)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    3630 (INS)
   04910 Insulin signaling pathway
    3630 (INS)
   04923 Regulation of lipolysis in adipocyte
    3630 (INS)
   04913 Ovarian Steroidogenesis
    3630 (INS)
   04914 Progesterone-mediated oocyte maturation
    3630 (INS)
   04917 Prolactin signaling pathway
    3630 (INS)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    3630 (INS)
  Aging
   04211 Longevity regulating pathway - mammal
    3630 (INS)
   04213 Longevity regulating pathway - multiple species
    3630 (INS)
 Human Diseases
  Cancers
   05215 Prostate cancer
    3630 (INS)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    3630 (INS)
   04940 Type I diabetes mellitus
    3630 (INS)
   04950 Maturity onset diabetes of the young
    3630 (INS)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    3630 (INS)
   04931 Insulin resistance
    3630 (INS)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P01308(Tbio)
UniProt: 
Structure
PDB: 
3W7Y 5E7W 5HQI 4FKA 3TT8 3W7Z 5USP 5UOZ 5URT 4AJX 5UU2 5HRQ 5USV 5UQA 5HPR 5UDP 5ENA 3EXX 2OMH 4CY7 4NIB 3W80 4EY1 4EY9 4EYD 5EN9 4XC4 4CXL 4P65 2WS6 2WRX 1ZEH 2OMG 4EYN 5BQQ 5T7R 4EXX 2WRU 4UNE 4F1B 4EYP 4IUZ 3ZU1 2WS1 3I3Z 3E7Y 1ZEG 1GUJ 4F4T 4F4V 4F51 4F1D 4F1G 4IYD 4EX1 4F0O 4F8F 4F1F 4F0N 5VIZ 5CO2 5CNY 5BOQ 4CXN 3ZI3 4F1C 3E7Z 2OLY 2OLZ 4RXW 5BTS 4GBC 4EWZ 5CO6 4IYF 4F1A 4AJZ 2VJZ 2CEU 1XDA 4UNG 3INC 3I40 4EX0 4GBN 5MT9 5BPO 3ZQR 3KQ6 2WS4 3ILG 1HTV 1TYL 1TYM 5CO9 2C8Q 1OS3 5UU4 3ZS2 2OM1 4EFX 3U4N 4FG3 3V19 3P2X 2W44 2R36 2QIU 1QIZ 1ZNJ 4AKJ 5MT3 3Q6E 2OM0 5USS 2R35 1W8P 2WS0 2WRV 5MAM 5HPU 4EWX 3V1G 3IR0 2VK0 2OMI 5UU3 2R34 1OS4 4AK0 5EMS 4EWW 3ROV 3P33 1QIY 1LPH 4GBK 1QJ0 5URU 2WRW 4GBI 4GBL 1B9E 2WS7 2WBY 4UNH 5WDM 2WC0 5CJO 4OGA 6BFC 6B70 6B3Q 3W11 4Q5Z 6CE9 3W12 3W13 6CEB 6CE7 5WBT 5MWQ 5MHD 2N2V 2N2W 2N2X 2MVC 2MVD 2MPI 2MPG 2MLI 2M2N 2M2O 2M2P 2M2M 2M1E 2LWZ 2LGB 2L1Y 2L1Z 2KXK 2KQQ 2KQP 2KJU 2KJJ 2K9R 2K91 2RN5 2JV1 2JMN 2HHO 2HH4 2H67 2C8R 1T0C 1UZ9 1SF1 1JCO 1IOG 1A7F 1SJT 1SJU 1AI0 1AIY 1VKT 1XGL 2HIU 1HUI 1HLS 1MHI 1MHJ 1HIQ 1HIS 1HIT
Thumbnails

Jmol
Position
11p15.5
AA seq 110 aa AA seqDB search
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED
LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
NT seq 333 nt NT seq  +upstreamnt  +downstreamnt
atggccctgtggatgcgcctcctgcccctgctggcgctgctggccctctggggacctgac
ccagccgcagcctttgtgaaccaacacctgtgcggctcacacctggtggaagctctctac
ctagtgtgcggggaacgaggcttcttctacacacccaagacccgccgggaggcagaggac
ctgcaggtggggcaggtggagctgggcgggggccctggtgcaggcagcctgcagcccttg
gccctggaggggtccctgcagaagcgtggcattgtggaacaatgctgtaccagcatctgc
tccctctaccagctggagaactactgcaactag

KEGG   Homo sapiens (human): 4254Help
Entry
4254              CDS       T01001                                 

Gene name
KITLG, DCUA, DFNA69, FPH2, FPHH, KL-1, Kitl, MGF, SCF, SF, SHEP7, SLF
Definition
(RefSeq) KIT ligand
  KO
K05461  
KIT ligand
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
Phospholipase D signaling pathway
PI3K-Akt signaling pathway
Hematopoietic cell lineage
Melanogenesis
Pathways in cancer
Network
N00045  
KITLG-KIT-PI3K signaling pathway
N00215  
KITLG-KIT-RAS-ERK signaling pathway
Disease
H00884  
Familial progressive hyperpigmentation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    4254 (KITLG)
   04015 Rap1 signaling pathway
    4254 (KITLG)
   04010 MAPK signaling pathway
    4254 (KITLG)
   04072 Phospholipase D signaling pathway
    4254 (KITLG)
   04151 PI3K-Akt signaling pathway
    4254 (KITLG)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    4254 (KITLG)
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    4254 (KITLG)
  Endocrine system
   04916 Melanogenesis
    4254 (KITLG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    4254 (KITLG)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   4254 (KITLG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P21583(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
12q21.32
AA seq 273 aa AA seqDB search
MKKTQTWILTCIYLQLLLFNPLVKTEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPG
MDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSS
KDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEKDSRVSVT
KPFMLPPVAASSLRNDSSSSNRKAKNPPGDSSLHWAAMALPALFSLIIGFAFGALYWKKR
QPSLTRAVENIQINEEDNEISMLQEKEREFQEV
NT seq 822 nt NT seq  +upstreamnt  +downstreamnt
atgaagaagacacaaacttggattctcacttgcatttatcttcagctgctcctatttaat
cctctcgtcaaaactgaagggatctgcaggaatcgtgtgactaataatgtaaaagacgtc
actaaattggtggcaaatcttccaaaagactacatgataaccctcaaatatgtccccggg
atggatgttttgccaagtcattgttggataagcgagatggtagtacaattgtcagacagc
ttgactgatcttctggacaagttttcaaatatttctgaaggcttgagtaattattccatc
atagacaaacttgtgaatatagtggatgaccttgtggagtgcgtgaaagaaaactcatct
aaggatctaaaaaaatcattcaagagcccagaacccaggctctttactcctgaagaattc
tttagaatttttaatagatccattgatgccttcaaggactttgtagtggcatctgaaact
agtgattgtgtggtttcttcaacattaagtcctgagaaagattccagagtcagtgtcaca
aaaccatttatgttaccccctgttgcagccagctcccttaggaatgacagcagtagcagt
aataggaaggccaaaaatccccctggagactccagcctacactgggcagccatggcattg
ccagcattgttttctcttataattggctttgcttttggagccttatactggaagaagaga
cagccaagtcttacaagggcagttgaaaatatacaaattaatgaagaggataatgagata
agtatgttgcaagagaaagagagagagtttcaagaagtgtaa

KEGG   Homo sapiens (human): 4803Help
Entry
4803              CDS       T01001                                 

Gene name
NGF, Beta-NGF, HSAN5, NGFB
Definition
(RefSeq) nerve growth factor
  KO
K02582  
nerve growth factor, beta
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Disease
H00265  
Hereditary sensory and autonomic neuropathy (HSAN)
Drug target
Fulranumab: 
Tanezumab: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    4803 (NGF)
   04015 Rap1 signaling pathway
    4803 (NGF)
   04010 MAPK signaling pathway
    4803 (NGF)
   04151 PI3K-Akt signaling pathway
    4803 (NGF)
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    4803 (NGF)
 Organismal Systems
  Nervous system
   04722 Neurotrophin signaling pathway
    4803 (NGF)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    4803 (NGF)
Chaperones and folding catalysts [BR:hsa03110]
 Intramolecular chaperones
  Others
   4803 (NGF)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass II
    4803 (NGF)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P01138(Tchem)
UniProt: 
Structure
PDB: 

Jmol
Position
1p13.2
AA seq 241 aa AA seqDB search
MSMLFYTLITAFLIGIQAEPHSESNVPAGHTIPQAHWTKLQHSLDTALRRARSAPAAAIA
ARVAGQTRNITVDPRLFKKRRLRSPRVLFSTQPPREAADTQDLDFEVGGAAPFNRTHRSK
RSSSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCR
DPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSRKAVRR
A
NT seq 726 nt NT seq  +upstreamnt  +downstreamnt
atgtccatgttgttctacactctgatcacagcttttctgatcggcatacaggcggaacca
cactcagagagcaatgtccctgcaggacacaccatcccccaagcccactggactaaactt
cagcattcccttgacactgcccttcgcagagcccgcagcgccccggcagcggcgatagct
gcacgcgtggcggggcagacccgcaacattactgtggaccccaggctgtttaaaaagcgg
cgactccgttcaccccgtgtgctgtttagcacccagcctccccgtgaagctgcagacact
caggatctggacttcgaggtcggtggtgctgcccccttcaacaggactcacaggagcaag
cggtcatcatcccatcccatcttccacaggggcgaattctcggtgtgtgacagtgtcagc
gtgtgggttggggataagaccaccgccacagacatcaagggcaaggaggtgatggtgttg
ggagaggtgaacattaacaacagtgtattcaaacagtacttttttgagaccaagtgccgg
gacccaaatcccgttgacagcgggtgccggggcattgactcaaagcactggaactcatat
tgtaccacgactcacacctttgtcaaggcgctgaccatggatggcaagcaggctgcctgg
cggtttatccggatagatacggcctgtgtgtgtgtgctcagcaggaaggctgtgagaaga
gcctga

KEGG   Homo sapiens (human): 4908Help
Entry
4908              CDS       T01001                                 

Gene name
NTF3, HDNF, NGF-2, NGF2, NT-3, NT3
Definition
(RefSeq) neurotrophin 3
  KO
K04356  
neurotrophin 3
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
PI3K-Akt signaling pathway
Neurotrophin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    4908 (NTF3)
   04010 MAPK signaling pathway
    4908 (NTF3)
   04151 PI3K-Akt signaling pathway
    4908 (NTF3)
 Organismal Systems
  Nervous system
   04722 Neurotrophin signaling pathway
    4908 (NTF3)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass II
    4908 (NTF3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P20783(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
12p13.31
AA seq 257 aa AA seqDB search
MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ
STLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLM
EDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIK
TGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWI
RIDTSCVCALSRKIGRT
NT seq 774 nt NT seq  +upstreamnt  +downstreamnt
atgtccatcttgttttatgtgatatttctcgcttatctccgtggcatccaaggtaacaac
atggatcaaaggagtttgccagaagactcgctcaattccctcattattaagctgatccag
gcagatattttgaaaaacaagctctccaagcagatggtggacgttaaggaaaattaccag
agcaccctgcccaaagctgaggctccccgagagccggagcggggagggcccgccaagtca
gcattccagccggtgattgcaatggacaccgaactgctgcgacaacagagacgctacaac
tcaccgcgggtcctgctgagcgacagcacccccttggagcccccgcccttgtatctcatg
gaggattacgtgggcagccccgtggtggcgaacagaacatcacggcggaaacggtacgcg
gagcataagagtcaccgaggggagtactcggtatgtgacagtgagagtctgtgggtgacc
gacaagtcatcggccatcgacattcggggacaccaggtcacggtgctgggggagatcaaa
acgggcaactctcccgtcaaacaatatttttatgaaacgcgatgtaaggaagccaggccg
gtcaaaaacggttgcaggggtattgatgataaacactggaactctcagtgcaaaacatcc
caaacctacgtccgagcactgacttcagagaacaataaactcgtgggctggcggtggata
cggatagacacgtcctgtgtgtgtgccttgtcgagaaaaatcggaagaacatga

KEGG   Homo sapiens (human): 4909Help
Entry
4909              CDS       T01001                                 

Gene name
NTF4, GLC10, GLC1O, NT-4, NT-4/5, NT-5, NT4, NT5, NTF5
Definition
(RefSeq) neurotrophin 4
  KO
K12457  
neurotrophin 4
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
PI3K-Akt signaling pathway
Neurotrophin signaling pathway
Disease
H00612  
Primary open angle glaucoma
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    4909 (NTF4)
   04010 MAPK signaling pathway
    4909 (NTF4)
   04151 PI3K-Akt signaling pathway
    4909 (NTF4)
 Organismal Systems
  Nervous system
   04722 Neurotrophin signaling pathway
    4909 (NTF4)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass II
    4909 (NTF4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P34130(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
19q13.33
AA seq 210 aa AA seqDB search
MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
TADAQGRVGWRWIRIDTACVCTLLSRTGRA
NT seq 633 nt NT seq  +upstreamnt  +downstreamnt
atgctccctctcccctcatgctccctccccatcctcctccttttcctcctccccagtgtg
ccaattgagtcccaacccccaccctcaacattgcccccttttctggcccctgagtgggac
cttctctccccccgagtagtcctgtctaggggtgcccctgctgggccccctctgctcttc
ctgctggaggctggggcctttcgggagtcagcaggtgccccggccaaccgcagccggcgt
ggggtgagcgaaactgcaccagcgagtcgtcggggtgagctggctgtgtgcgatgcagtc
agtggctgggtgacagaccgccggaccgctgtggacttgcgtgggcgcgaggtggaggtg
ttgggcgaggtgcctgcagctggcggcagtcccctccgccagtacttctttgaaacccgc
tgcaaggctgataacgctgaggaaggtggcccgggggcaggtggagggggctgccgggga
gtggacaggaggcactgggtatctgagtgcaaggccaagcagtcctatgtgcgggcattg
accgctgatgcccagggccgtgtgggctggcgatggattcgaattgacactgcctgcgtc
tgcacactcctcagccggactggccgggcctga

KEGG   Homo sapiens (human): 51378Help
Entry
51378             CDS       T01001                                 

Gene name
ANGPT4, ANG3, ANG4
Definition
(RefSeq) angiopoietin 4
  KO
K05467  
angiopoietin 4
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
HIF-1 signaling pathway
PI3K-Akt signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    51378 (ANGPT4)
   04015 Rap1 signaling pathway
    51378 (ANGPT4)
   04010 MAPK signaling pathway
    51378 (ANGPT4)
   04066 HIF-1 signaling pathway
    51378 (ANGPT4)
   04151 PI3K-Akt signaling pathway
    51378 (ANGPT4)
Cytokines [BR:hsa04052]
 PDGF family
  Other growth factors
   51378 (ANGPT4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q9Y264(Tbio)
UniProt: 
Position
20p13
AA seq 503 aa AA seqDB search
MLSQLAMLQGSLLLVVATMSVAQQTRQEADRGCETLVVQHGHCSYTFLLPKSEPCPPGPE
VSRDSNTLQRESLANPLHLGKLPTQQVKQLEQALQNNTQWLKKLERAIKTILRSKLEQVQ
QQMAQNQTAPMLELGTSLLNQTTAQIRKLTDMEAQLLNQTSRMDAQMPETFLSTNKLENQ
LLLQRQKLQQLQGQNSALEKRLQALETKQQEELASILSKKAKLLNTLSRQSAALTNIERG
LRGVRHNSSLLQDQQHSLRQLLVLLRHLVQERANASAPAFIMAGEQVFQDCAEIQRSGAS
ASGVYTIQVSNATKPRKVFCDLQSSGGRWTLIQRRENGTVNFQRNWKDYKQGFGDPAGEH
WLGNEVVHQLTRRAAYSLRVELQDWEGHEAYAQYEHFHLGSENQLYRLSVVGYSGSAGRQ
SSLVLQNTSFSTLDSDNDHCLCKCAQVMSGGWWFDACGLSNLNGVYYHAPDNKYKMDGIR
WHYFKGPSYSLRASRMMIRPLDI
NT seq 1512 nt NT seq  +upstreamnt  +downstreamnt
atgctctcccagctagccatgctgcagggcagcctcctccttgtggttgccaccatgtct
gtggctcaacagacaaggcaggaggcggataggggctgcgagacacttgtagtccagcac
ggccactgtagctacaccttcttgctgcccaagtctgagccctgccctccggggcctgag
gtctccagggactccaacaccctccagagagaatcactggccaacccactgcacctgggg
aagttgcccacccagcaggtgaaacagctggagcaggcactgcagaacaacacgcagtgg
ctgaagaagctagagagggccatcaagacgatcttgaggtcgaagctggagcaggtccag
cagcaaatggcccagaatcagacggcccccatgctagagctgggcaccagcctcctgaac
cagaccactgcccagatccgcaagctgaccgacatggaggctcagctcctgaaccagaca
tcaagaatggatgcccagatgccagagacctttctgtccaccaacaagctggagaaccag
ctgctgctacagaggcagaagctccagcagcttcagggccaaaacagcgcgctcgagaag
cggttgcaggccctggagaccaagcagcaggaggagctggccagcatcctcagcaagaag
gcgaagctgctgaacacgctgagccgccagagcgccgccctcaccaacatcgagcgcggc
ctgcgcggtgtcaggcacaactccagcctcctgcaggaccagcagcacagcctgcgccag
ctgctggtgttgttgcggcacctggtgcaagaaagggctaacgcctcggccccggccttc
ataatggcaggtgagcaggtgttccaggactgtgcagagatccagcgctctggggccagt
gccagtggtgtctacaccatccaggtgtccaatgcaacgaagcccaggaaggtgttctgt
gacctgcagagcagtggaggcaggtggaccctcatccagcgccgtgagaatggcaccgtg
aattttcagcggaactggaaggattacaaacagggcttcggagacccagctggggagcac
tggctgggcaatgaagtggtgcaccagctcaccagaagggcagcctactctctgcgtgtg
gagctgcaagactgggaaggccacgaggcctatgcccagtacgaacatttccacctgggc
agtgagaaccagctatacaggctttctgtggtcgggtacagcggctcagcagggcgccag
agcagcctggtcctgcagaacaccagctttagcacccttgactcagacaacgaccactgt
ctctgcaagtgtgcccaagtgatgtctggagggtggtggtttgacgcctgtggcctgtca
aacctcaacggcgtctactaccacgctcccgacaacaagtacaagatggacggcatccgc
tggcactacttcaagggccccagctactcactgcgtgcctctcgcatgatgatacggcct
ttggacatctaa

KEGG   Homo sapiens (human): 5154Help
Entry
5154              CDS       T01001                                 

Gene name
PDGFA, PDGF-A, PDGF1
Definition
(RefSeq) platelet derived growth factor subunit A
  KO
K04359  
platelet-derived growth factor subunit A
Organism
hsa  Homo sapiens (human)
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
Phospholipase D signaling pathway
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Regulation of actin cytoskeleton
HTLV-I infection
Pathways in cancer
Transcriptional misregulation in cancer
MicroRNAs in cancer
Glioma
Prostate cancer
Melanoma
Choline metabolism in cancer
Fluid shear stress and atherosclerosis
Network
N00015  
PDGF-PDGFR-RAS-ERK signaling pathway
N00016  
PDGF-overexpression to RAS-ERK signaling pathway
N00028  
PDGF-PDGFR-PLCG-CAMK signaling pathway
N00039  
PDGF-PDGFR-PI3K signaling pathway
N00137  
EWSR1-WT1 fusion to transcriptional activation
Disease
H00015  
Malignant pleural mesothelioma
H00042  
Glioma
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    5154 (PDGFA)
   04015 Rap1 signaling pathway
    5154 (PDGFA)
   04010 MAPK signaling pathway
    5154 (PDGFA)
   04630 Jak-STAT signaling pathway
    5154 (PDGFA)
   04072 Phospholipase D signaling pathway
    5154 (PDGFA)
   04151 PI3K-Akt signaling pathway
    5154 (PDGFA)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    5154 (PDGFA)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    5154 (PDGFA)
   04540 Gap junction
    5154 (PDGFA)
  Cell motility
   04810 Regulation of actin cytoskeleton
    5154 (PDGFA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    5154 (PDGFA)
   05231 Choline metabolism in cancer
    5154 (PDGFA)
   05202 Transcriptional misregulation in cancers
    5154 (PDGFA)
   05206 MicroRNAs in cancer
    5154 (PDGFA)
   05214 Glioma
    5154 (PDGFA)
   05218 Melanoma
    5154 (PDGFA)
   05215 Prostate cancer
    5154 (PDGFA)
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    5154 (PDGFA)
  Infectious diseases
   05166 HTLV-I infection
    5154 (PDGFA)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    5154 (PDGFA)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass I
    5154 (PDGFA)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    PDGFRA; platelet-derived growth factor receptor, alpha polypeptide [KO:K04363]
     5154 (PDGFA)
    PDGFRB; platelet-derived growth factor receptor, beta polypeptide [KO:K05089]
     5154 (PDGFA)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   5154 (PDGFA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P04085(Tchem)
UniProt: 
Structure
PDB: 

Jmol
Position
7p22.3
AA seq 211 aa AA seqDB search
MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
TTSLNPDYREEDTGRPRESGKKRKRKRLKPT
NT seq 636 nt NT seq  +upstreamnt  +downstreamnt
atgaggaccttggcttgcctgctgctcctcggctgcggatacctcgcccatgttctggcc
gaggaagccgagatcccccgcgaggtgatcgagaggctggcccgcagtcagatccacagc
atccgggacctccagcgactcctggagatagactccgtagggagtgaggattctttggac
accagcctgagagctcacggggtccatgccactaagcatgtgcccgagaagcggcccctg
cccattcggaggaagagaagcatcgaggaagctgtccccgctgtctgcaagaccaggacg
gtcatttacgagattcctcggagtcaggtcgaccccacgtccgccaacttcctgatctgg
cccccgtgcgtggaggtgaaacgctgcaccggctgctgcaacacgagcagtgtcaagtgc
cagccctcccgcgtccaccaccgcagcgtcaaggtggccaaggtggaatacgtcaggaag
aagccaaaattaaaagaagtccaggtgaggttagaggagcatttggagtgcgcctgcgcg
accacaagcctgaatccggattatcgggaagaggacacgggaaggcctagggagtcaggt
aaaaaacggaaaagaaaaaggttaaaacccacctaa

KEGG   Homo sapiens (human): 5155Help
Entry
5155              CDS       T01001                                 

Gene name
PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis
Definition
(RefSeq) platelet derived growth factor subunit B
  KO
K17386  
platelet-derived growth factor subunit B
Organism
hsa  Homo sapiens (human)
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
Phospholipase D signaling pathway
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Regulation of actin cytoskeleton
HTLV-I infection
Kaposi's sarcoma-associated herpesvirus infection
Pathways in cancer
MicroRNAs in cancer
Renal cell carcinoma
Glioma
Prostate cancer
Melanoma
Choline metabolism in cancer
Fluid shear stress and atherosclerosis
Network
N00015  
PDGF-PDGFR-RAS-ERK signaling pathway
N00016  
PDGF-overexpression to RAS-ERK signaling pathway
N00028  
PDGF-PDGFR-PLCG-CAMK signaling pathway
N00039  
PDGF-PDGFR-PI3K signaling pathway
N00079  
HIF-1 signaling pathway
N00080  
Loss of VHL to HIF-1 signaling pathway
N00081  
Mutation-inactivated VHL to HIF-1 signaling pathway
N00157  
KSHV vGPCR to GNB/G-ERK signaling pathway
Disease
H00015  
Malignant pleural mesothelioma
H00042  
Glioma
H01574  
Familial idiopathic basal ganglia calcification
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    5155 (PDGFB)
   04015 Rap1 signaling pathway
    5155 (PDGFB)
   04010 MAPK signaling pathway
    5155 (PDGFB)
   04630 Jak-STAT signaling pathway
    5155 (PDGFB)
   04072 Phospholipase D signaling pathway
    5155 (PDGFB)
   04151 PI3K-Akt signaling pathway
    5155 (PDGFB)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    5155 (PDGFB)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    5155 (PDGFB)
   04540 Gap junction
    5155 (PDGFB)
  Cell motility
   04810 Regulation of actin cytoskeleton
    5155 (PDGFB)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    5155 (PDGFB)
   05231 Choline metabolism in cancer
    5155 (PDGFB)
   05206 MicroRNAs in cancer
    5155 (PDGFB)
   05214 Glioma
    5155 (PDGFB)
   05218 Melanoma
    5155 (PDGFB)
   05211 Renal cell carcinoma
    5155 (PDGFB)
   05215 Prostate cancer
    5155 (PDGFB)
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    5155 (PDGFB)
  Infectious diseases
   05166 HTLV-I infection
    5155 (PDGFB)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    5155 (PDGFB)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    5155 (PDGFB)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass I
    5155 (PDGFB)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    PDGFRA; platelet-derived growth factor receptor, alpha polypeptide [KO:K04363]
     5155 (PDGFB)
    PDGFRB; platelet-derived growth factor receptor, beta polypeptide [KO:K05089]
     5155 (PDGFB)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   5155 (PDGFB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P01127(Tchem)
UniProt: 
Structure
PDB: 

Jmol
Position
22q13.1
AA seq 241 aa AA seqDB search
MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDPGEEDGAEL
DLNMTRSHSGGELESLARGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
WPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKC
ETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLG
A
NT seq 726 nt NT seq  +upstreamnt  +downstreamnt
atgaatcgctgctgggcgctcttcctgtctctctgctgctacctgcgtctggtcagcgcc
gagggggaccccattcccgaggagctttatgagatgctgagtgaccactcgatccgctcc
tttgatgatctccaacgcctgctgcacggagaccccggagaggaagatggggccgagttg
gacctgaacatgacccgctcccactctggaggcgagctggagagcttggctcgtggaaga
aggagcctgggttccctgaccattgctgagccggccatgatcgccgagtgcaagacgcgc
accgaggtgttcgagatctcccggcgcctcatagaccgcaccaacgccaacttcctggtg
tggccgccctgtgtggaggtgcagcgctgctccggctgctgcaacaaccgcaacgtgcag
tgccgccccacccaggtgcagctgcgacctgtccaggtgagaaagatcgagattgtgcgg
aagaagccaatctttaagaaggccacggtgacgctggaagaccacctggcatgcaagtgt
gagacagtggcagctgcacggcctgtgacccgaagcccggggggttcccaggagcagcga
gccaaaacgccccaaactcgggtgaccattcggacggtgcgagtccgccggccccccaag
ggcaagcaccggaaattcaagcacacgcatgacaagacggcactgaaggagacccttgga
gcctag

KEGG   Homo sapiens (human): 5228Help
Entry
5228              CDS       T01001                                 

Gene name
PGF, D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760
Definition
(RefSeq) placental growth factor
  KO
K16859  
placenta growth factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
PI3K-Akt signaling pathway
Focal adhesion
Pathways in cancer
Drug target
Aflibercept: 
Aflibercept beta: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    5228 (PGF)
   04015 Rap1 signaling pathway
    5228 (PGF)
   04010 MAPK signaling pathway
    5228 (PGF)
   04151 PI3K-Akt signaling pathway
    5228 (PGF)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    5228 (PGF)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    5228 (PGF)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass I
    5228 (PGF)
Cell adhesion molecules and their ligands [BR:hsa04516]
 7. Others
  NRP1; neuropilin 1 [KO:K06724]
   5228 (PGF)
  NRP2; neuropilin 2 [KO:K06819]
   5228 (PGF)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P49763(Tclin)
UniProt: 
Structure
PDB: 

Jmol
Position
14q24.3
AA seq 170 aa AA seqDB search
MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
TFSQHVRCECRPLREKMKPERRRPKGRGKRRREKQRPTDCHLCGDAVPRR
NT seq 513 nt NT seq  +upstreamnt  +downstreamnt
atgccggtcatgaggctgttcccttgcttcctgcagctcctggccgggctggcgctgcct
gctgtgcccccccagcagtgggccttgtctgctgggaacggctcgtcagaggtggaagtg
gtacccttccaggaagtgtggggccgcagctactgccgggcgctggagaggctggtggac
gtcgtgtccgagtaccccagcgaggtggagcacatgttcagcccatcctgtgtctccctg
ctgcgctgcaccggctgctgcggcgatgagaatctgcactgtgtgccggtggagacggcc
aatgtcaccatgcagctcctaaagatccgttctggggaccggccctcctacgtggagctg
acgttctctcagcacgttcgctgcgaatgccggcctctgcgggagaagatgaagccggaa
aggaggagacccaagggcagggggaagaggaggagagagaagcagagacccacagactgc
cacctgtgcggcgatgctgttccccggaggtaa

KEGG   Homo sapiens (human): 56034Help
Entry
56034             CDS       T01001                                 

Gene name
PDGFC, FALLOTEIN, SCDGF
Definition
(RefSeq) platelet derived growth factor C
  KO
K05450  
platelet derived growth factor C/D
Organism
hsa  Homo sapiens (human)
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
Phospholipase D signaling pathway
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
Prostate cancer
Melanoma
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    56034 (PDGFC)
   04015 Rap1 signaling pathway
    56034 (PDGFC)
   04010 MAPK signaling pathway
    56034 (PDGFC)
   04072 Phospholipase D signaling pathway
    56034 (PDGFC)
   04151 PI3K-Akt signaling pathway
    56034 (PDGFC)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    56034 (PDGFC)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    56034 (PDGFC)
   04540 Gap junction
    56034 (PDGFC)
  Cell motility
   04810 Regulation of actin cytoskeleton
    56034 (PDGFC)
 Human Diseases
  Cancers
   05231 Choline metabolism in cancer
    56034 (PDGFC)
   05218 Melanoma
    56034 (PDGFC)
   05215 Prostate cancer
    56034 (PDGFC)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    56034 (PDGFC)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass I
    56034 (PDGFC)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    PDGFRA; platelet-derived growth factor receptor, alpha polypeptide [KO:K04363]
     56034 (PDGFC)
    PDGFRB; platelet-derived growth factor receptor, beta polypeptide [KO:K05089]
     56034 (PDGFC)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q9NRA1(Tbio)
UniProt: 
Position
4q32.1
AA seq 345 aa AA seqDB search
MSLFGLLLLTSALAGQRQGTQAESNLSSKFQFSSNKEQNGVQDPQHERIITVSTNGSIHS
PRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGTIL
GRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVSPSVLPPSA
LPLDLLNNAITAFSTLEDLIRYLEPERWQLDLEDLYRPTWQLLGKAFVFGRKSRVVDLNL
LTEEVRLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSK
VTKKYHEVLQLRPKTGVRGLHKSLTDVALEHHEECDCVCRGSTGG
NT seq 1038 nt NT seq  +upstreamnt  +downstreamnt
atgagcctcttcgggcttctcctgctgacatctgccctggccggccagagacaggggact
caggcggaatccaacctgagtagtaaattccagttttccagcaacaaggaacagaacgga
gtacaagatcctcagcatgagagaattattactgtgtctactaatggaagtattcacagc
ccaaggtttcctcatacttatccaagaaatacggtcttggtatggagattagtagcagta
gaggaaaatgtatggatacaacttacgtttgatgaaagatttgggcttgaagacccagaa
gatgacatatgcaagtatgattttgtagaagttgaggaacccagtgatggaactatatta
gggcgctggtgtggttctggtactgtaccaggaaaacagatttctaaaggaaatcaaatt
aggataagatttgtatctgatgaatattttccttctgaaccagggttctgcatccactac
aacattgtcatgccacaattcacagaagctgtgagtccttcagtgctacccccttcagct
ttgccactggacctgcttaataatgctataactgcctttagtaccttggaagaccttatt
cgatatcttgaaccagagagatggcagttggacttagaagatctatataggccaacttgg
caacttcttggcaaggcttttgtttttggaagaaaatccagagtggtggatctgaacctt
ctaacagaggaggtaagattatacagctgcacacctcgtaacttctcagtgtccataagg
gaagaactaaagagaaccgataccattttctggccaggttgtctcctggttaaacgctgt
ggtgggaactgtgcctgttgtctccacaattgcaatgaatgtcaatgtgtcccaagcaaa
gttactaaaaaataccacgaggtccttcagttgagaccaaagaccggtgtcaggggattg
cacaaatcactcaccgacgtggccctggagcaccatgaggagtgtgactgtgtgtgcaga
gggagcacaggaggatag

KEGG   Homo sapiens (human): 627Help
Entry
627               CDS       T01001                                 

Gene name
BDNF, ANON2, BULN2
Definition
(RefSeq) brain derived neurotrophic factor
  KO
K04355  
brain-derived neurotrophic factor
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
cAMP signaling pathway
PI3K-Akt signaling pathway
Neurotrophin signaling pathway
Huntington's disease
Cocaine addiction
Alcoholism
Disease
H00916  
Congenital central hypoventilation syndrome (CCHS)
H01450  
Obsessive-compulsive disorder (OCD)
H01703  
Eating Disorders
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    627 (BDNF)
   04010 MAPK signaling pathway
    627 (BDNF)
   04024 cAMP signaling pathway
    627 (BDNF)
   04151 PI3K-Akt signaling pathway
    627 (BDNF)
 Organismal Systems
  Nervous system
   04722 Neurotrophin signaling pathway
    627 (BDNF)
 Human Diseases
  Neurodegenerative diseases
   05016 Huntington's disease
    627 (BDNF)
  Substance dependence
   05030 Cocaine addiction
    627 (BDNF)
   05034 Alcoholism
    627 (BDNF)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass II
    627 (BDNF)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P23560(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
11p14.1
AA seq 247 aa AA seqDB search
MTILFLTMVISYFGCMKAAPMKEANIRGQGGLAYPGVRTHGTLESVNGPKAGSRGLTSLA
DTFEHVIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAA
NMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQY
FYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCT
LTIKRGR
NT seq 744 nt NT seq  +upstreamnt  +downstreamnt
atgaccatccttttccttactatggttatttcatactttggttgcatgaaggctgccccc
atgaaagaagcaaacatccgaggacaaggtggcttggcctacccaggtgtgcggacccat
gggactctggagagcgtgaatgggcccaaggcaggttcaagaggcttgacatcattggct
gacactttcgaacacgtgatagaagagctgttggatgaggaccagaaagttcggcccaat
gaagaaaacaataaggacgcagacttgtacacgtccagggtgatgctcagtagtcaagtg
cctttggagcctcctcttctctttctgctggaggaatacaaaaattacctagatgctgca
aacatgtccatgagggtccggcgccactctgaccctgcccgccgaggggagctgagcgtg
tgtgacagtattagtgagtgggtaacggcggcagacaaaaagactgcagtggacatgtcg
ggcgggacggtcacagtccttgaaaaggtccctgtatcaaaaggccaactgaagcaatac
ttctacgagaccaagtgcaatcccatgggttacacaaaagaaggctgcaggggcatagac
aaaaggcattggaactcccagtgccgaactacccagtcgtacgtgcgggcccttaccatg
gatagcaaaaagagaattggctggcgattcataaggatagacacttcttgtgtatgtaca
ttgaccattaaaaggggaagatag

KEGG   Homo sapiens (human): 7039Help
Entry
7039              CDS       T01001                                 

Gene name
TGFA, TFGA
Definition
(RefSeq) transforming growth factor alpha
  KO
K08774  
transforming growth factor, alpha
Organism
hsa  Homo sapiens (human)
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
PI3K-Akt signaling pathway
Estrogen signaling pathway
Pathways in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Glioma
Prostate cancer
Non-small cell lung cancer
Hepatocellular carcinoma
Network
N00079  
HIF-1 signaling pathway
N00080  
Loss of VHL to HIF-1 signaling pathway
N00081  
Mutation-inactivated VHL to HIF-1 signaling pathway
N00227  
TGFA-EGFR-PLCG-PKC signaling pathway
N00228  
TGFA-overexpression to PLCG-PKC signaling pathway
N00229  
TGFA-EGFR-RAS-ERK signaling pathway
N00230  
TGFA-overexpression to RAS-ERK signaling pathway
N00231  
TGFA-EGFR-PI3K signaling pathway
N00232  
TGFA-overexpression to PI3K signaling pathway
Disease
H00048  
Hepatocellular carcinoma
H00516  
Cleft lip and/or cleft palate
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    7039 (TGFA)
   04010 MAPK signaling pathway
    7039 (TGFA)
   04012 ErbB signaling pathway
    7039 (TGFA)
   04151 PI3K-Akt signaling pathway
    7039 (TGFA)
 Organismal Systems
  Endocrine system
   04915 Estrogen signaling pathway
    7039 (TGFA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    7039 (TGFA)
   05210 Colorectal cancer
    7039 (TGFA)
   05212 Pancreatic cancer
    7039 (TGFA)
   05225 Hepatocellular carcinoma
    7039 (TGFA)
   05214 Glioma
    7039 (TGFA)
   05211 Renal cell carcinoma
    7039 (TGFA)
   05215 Prostate cancer
    7039 (TGFA)
   05223 Non-small cell lung cancer
    7039 (TGFA)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    7039 (TGFA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P01135(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
2p13.3
AA seq 160 aa AA seqDB search
MVPSAGQLALFALGIVLAACQALENSTSPLSADPPVAAAVVSHFNDCPDSHTQFCFHGTC
RFLVQEDKPACVCHSGYVGARCEHADLLAVVAASQKKQAITALVVVSIVALAVLIITCVL
IHCCQVRKHCEWCRALICRHEKPSALLKGRTACCHSETVV
NT seq 483 nt NT seq  +upstreamnt  +downstreamnt
atggtcccctcggctggacagctcgccctgttcgctctgggtattgtgttggctgcgtgc
caggccttggagaacagcacgtccccgctgagtgcagacccgcccgtggctgcagcagtg
gtgtcccattttaatgactgcccagattcccacactcagttctgcttccatggaacctgc
aggtttttggtgcaggaggacaagccagcatgtgtctgccattctgggtacgttggtgca
cgctgtgagcatgcggacctcctggccgtggtggctgccagccagaagaagcaggccatc
accgccttggtggtggtctccatcgtggccctggctgtccttatcatcacatgtgtgctg
atacactgctgccaggtccgaaaacactgtgagtggtgccgggccctcatctgccggcac
gagaagcccagcgccctcctgaagggaagaaccgcttgctgccactcagaaacagtggtc
tga

KEGG   Homo sapiens (human): 7422Help
Entry
7422              CDS       T01001                                 

Gene name
VEGFA, MVCD1, VEGF, VPF
Definition
(RefSeq) vascular endothelial growth factor A
  KO
K05448  
vascular endothelial growth factor A
Organism
hsa  Homo sapiens (human)
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
HIF-1 signaling pathway
PI3K-Akt signaling pathway
VEGF signaling pathway
Focal adhesion
Relaxin signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Human papillomavirus infection
Kaposi's sarcoma-associated herpesvirus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Pancreatic cancer
Bladder cancer
Rheumatoid arthritis
Fluid shear stress and atherosclerosis
Network
N00079  
HIF-1 signaling pathway
N00080  
Loss of VHL to HIF-1 signaling pathway
N00081  
Mutation-inactivated VHL to HIF-1 signaling pathway
N00095  
ERBB2-overexpression to EGF-Jak-STAT signaling pathway
N00157  
KSHV vGPCR to GNB/G-ERK signaling pathway
N00179  
KSHV K1 to PI3K-NFKB signaling pathway
Disease
H01456  
Diabetic nephropathy
H01457  
Diabetic retinopathy
H01459  
Diabetic neuropathy
H01529  
Avascular necrosis of femoral head
H01709  
Glucocorticoid-induced osteonecrosis
Drug target
Aflibercept: 
Aflibercept beta: 
Bevacizumab: 
Bevasiranib sodium: 
Pegaptanib: 
Ranibizumab: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    7422 (VEGFA)
   04015 Rap1 signaling pathway
    7422 (VEGFA)
   04010 MAPK signaling pathway
    7422 (VEGFA)
   04370 VEGF signaling pathway
    7422 (VEGFA)
   04066 HIF-1 signaling pathway
    7422 (VEGFA)
   04151 PI3K-Akt signaling pathway
    7422 (VEGFA)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    7422 (VEGFA)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    7422 (VEGFA)
 Organismal Systems
  Endocrine system
   04926 Relaxin signaling pathway
    7422 (VEGFA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    7422 (VEGFA)
   05206 MicroRNAs in cancer
    7422 (VEGFA)
   05205 Proteoglycans in cancer
    7422 (VEGFA)
   05212 Pancreatic cancer
    7422 (VEGFA)
   05211 Renal cell carcinoma
    7422 (VEGFA)
   05219 Bladder cancer
    7422 (VEGFA)
  Immune diseases
   05323 Rheumatoid arthritis
    7422 (VEGFA)
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    7422 (VEGFA)
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    7422 (VEGFA)
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    7422 (VEGFA)
   05165 Human papillomavirus infection
    7422 (VEGFA)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    7422 (VEGFA)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass I
    7422 (VEGFA)
Cell adhesion molecules and their ligands [BR:hsa04516]
 7. Others
  NRP1; neuropilin 1 [KO:K06724]
   7422 (VEGFA)
  NRP2; neuropilin 2 [KO:K06819]
   7422 (VEGFA)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Growth factors/receptors (General comment) Ligand-receptor clustering and signaling, cell migration, mitogenesis
   7422 (VEGFA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P15692(Tclin)
UniProt: 
Structure
PDB: 

Jmol
Position
6p21.1
AA seq 232 aa AA seqDB search
MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
SFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVYVGARCCLMPWSLPG
PHPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
NT seq 699 nt NT seq  +upstreamnt  +downstreamnt
atgaactttctgctgtcttgggtgcattggagccttgccttgctgctctacctccaccat
gccaagtggtcccaggctgcacccatggcagaaggaggagggcagaatcatcacgaagtg
gtgaagttcatggatgtctatcagcgcagctactgccatccaatcgagaccctggtggac
atcttccaggagtaccctgatgagatcgagtacatcttcaagccatcctgtgtgcccctg
atgcgatgcgggggctgctgcaatgacgagggcctggagtgtgtgcccactgaggagtcc
aacatcaccatgcagattatgcggatcaaacctcaccaaggccagcacataggagagatg
agcttcctacagcacaacaaatgtgaatgcagaccaaagaaagatagagcaagacaagaa
aaaaaatcagttcgaggaaagggaaaggggcaaaaacgaaagcgcaagaaatcccggtat
aagtcctggagcgtgtacgttggtgcccgctgctgtctaatgccctggagcctccctggc
ccccatccctgtgggccttgctcagagcggagaaagcatttgtttgtacaagatccgcag
acgtgtaaatgttcctgcaaaaacacagactcgcgttgcaaggcgaggcagcttgagtta
aacgaacgtacttgcagatgtgacaagccgaggcggtga

KEGG   Homo sapiens (human): 7423Help
Entry
7423              CDS       T01001                                 

Gene name
VEGFB, VEGFL, VRF
Definition
(RefSeq) vascular endothelial growth factor B
  KO
K16858  
vascular endothelial growth factor B
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Focal adhesion
Relaxin signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Pathways in cancer
Drug target
Aflibercept: 
Aflibercept beta: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    7423 (VEGFB)
   04015 Rap1 signaling pathway
    7423 (VEGFB)
   04010 MAPK signaling pathway
    7423 (VEGFB)
   04151 PI3K-Akt signaling pathway
    7423 (VEGFB)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    7423 (VEGFB)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    7423 (VEGFB)
 Organismal Systems
  Endocrine system
   04926 Relaxin signaling pathway
    7423 (VEGFB)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    7423 (VEGFB)
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    7423 (VEGFB)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass I
    7423 (VEGFB)
Cell adhesion molecules and their ligands [BR:hsa04516]
 7. Others
  NRP1; neuropilin 1 [KO:K06724]
   7423 (VEGFB)
  NRP2; neuropilin 2 [KO:K06819]
   7423 (VEGFB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P49765(Tclin)
UniProt: 
Structure
PDB: 

Jmol
Position
11q13.1
AA seq 207 aa AA seqDB search
MSPLLRRLLLAALLQLAPAQAPVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVEL
MGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHS
QCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGPSAHAAP
STTSALTPGPAAAAADAAASSVAKGGA
NT seq 624 nt NT seq  +upstreamnt  +downstreamnt
atgagccctctgctccgccgcctgctgctcgccgcactcctgcagctggcccccgcccag
gcccctgtctcccagcctgatgcccctggccaccagaggaaagtggtgtcatggatagat
gtgtatactcgcgctacctgccagccccgggaggtggtggtgcccttgactgtggagctc
atgggcaccgtggccaaacagctggtgcccagctgcgtgactgtgcagcgctgtggtggc
tgctgccctgacgatggcctggagtgtgtgcccactgggcagcaccaagtccggatgcag
atcctcatgatccggtacccgagcagtcagctgggggagatgtccctggaagaacacagc
cagtgtgaatgcagacctaaaaaaaaggacagtgctgtgaagccagacagggctgccact
ccccaccaccgtccccagccccgttctgttccgggctgggactctgcccccggagcaccc
tccccagctgacatcacccatcccactccagccccaggcccctctgcccacgctgcaccc
agcaccaccagcgccctgacccccggacctgccgctgccgctgccgacgccgcagcttcc
tccgttgccaagggcggggcttag

KEGG   Homo sapiens (human): 7424Help
Entry
7424              CDS       T01001                                 

Gene name
VEGFC, Flt4-L, LMPH1D, VRP
Definition
(RefSeq) vascular endothelial growth factor C
  KO
K05449  
vascular endothelial growth factor C/D
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Focal adhesion
TNF signaling pathway
Relaxin signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Pathways in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    7424 (VEGFC)
   04015 Rap1 signaling pathway
    7424 (VEGFC)
   04010 MAPK signaling pathway
    7424 (VEGFC)
   04668 TNF signaling pathway
    7424 (VEGFC)
   04151 PI3K-Akt signaling pathway
    7424 (VEGFC)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    7424 (VEGFC)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    7424 (VEGFC)
 Organismal Systems
  Endocrine system
   04926 Relaxin signaling pathway
    7424 (VEGFC)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    7424 (VEGFC)
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    7424 (VEGFC)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass I
    7424 (VEGFC)
Cell adhesion molecules and their ligands [BR:hsa04516]
 2. Integrin Family
  Beta1 integrins
   VLA-9
    ITGB1; integrin beta 1 [KO:K05719]
     7424 (VEGFC)
 7. Others
  NRP1; neuropilin 1 [KO:K06724]
   7424 (VEGFC)
  NRP2; neuropilin 2 [KO:K06819]
   7424 (VEGFC)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P49767(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
4q34.3
AA seq 419 aa AA seqDB search
MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATAYASKDLEEQL
RSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSRTEETIKFAAAHYNTEILK
SIDNEWRKTQCMPREVCIDVGKEFGVATNTFFKPPCVSVYRCGGCCNSEGLQCMNTSTSY
LSKTLFEITVPLSQGPKPVTISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAAN
KTCPTNYMWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR
PASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRNQPLNPGKCAC
ECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGFSYSEEVCRCVPSYWKRPQMS
NT seq 1260 nt NT seq  +upstreamnt  +downstreamnt
atgcacttgctgggcttcttctctgtggcgtgttctctgctcgccgctgcgctgctcccg
ggtcctcgcgaggcgcccgccgccgccgccgccttcgagtccggactcgacctctcggac
gcggagcccgacgcgggcgaggccacggcttatgcaagcaaagatctggaggagcagtta
cggtctgtgtccagtgtagatgaactcatgactgtactctacccagaatattggaaaatg
tacaagtgtcagctaaggaaaggaggctggcaacataacagagaacaggccaacctcaac
tcaaggacagaagagactataaaatttgctgcagcacattataatacagagatcttgaaa
agtattgataatgagtggagaaagactcaatgcatgccacgggaggtgtgtatagatgtg
gggaaggagtttggagtcgcgacaaacaccttctttaaacctccatgtgtgtccgtctac
agatgtgggggttgctgcaatagtgaggggctgcagtgcatgaacaccagcacgagctac
ctcagcaagacgttatttgaaattacagtgcctctctctcaaggccccaaaccagtaaca
atcagttttgccaatcacacttcctgccgatgcatgtctaaactggatgtttacagacaa
gttcattccattattagacgttccctgccagcaacactaccacagtgtcaggcagcgaac
aagacctgccccaccaattacatgtggaataatcacatctgcagatgcctggctcaggaa
gattttatgttttcctcggatgctggagatgactcaacagatggattccatgacatctgt
ggaccaaacaaggagctggatgaagagacctgtcagtgtgtctgcagagcggggcttcgg
cctgccagctgtggaccccacaaagaactagacagaaactcatgccagtgtgtctgtaaa
aacaaactcttccccagccaatgtggggccaaccgagaatttgatgaaaacacatgccag
tgtgtatgtaaaagaacctgccccagaaatcaacccctaaatcctggaaaatgtgcctgt
gaatgtacagaaagtccacagaaatgcttgttaaaaggaaagaagttccaccaccaaaca
tgcagctgttacagacggccatgtacgaaccgccagaaggcttgtgagccaggattttca
tatagtgaagaagtgtgtcgttgtgtcccttcatattggaaaagaccacaaatgagctaa

KEGG   Homo sapiens (human): 80310Help
Entry
80310             CDS       T01001                                 

Gene name
PDGFD, IEGF, MSTP036, SCDGF-B, SCDGFB
Definition
(RefSeq) platelet derived growth factor D
  KO
K05450  
platelet derived growth factor C/D
Organism
hsa  Homo sapiens (human)
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Phospholipase D signaling pathway
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
Prostate cancer
Melanoma
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    80310 (PDGFD)
   04015 Rap1 signaling pathway
    80310 (PDGFD)
   04010 MAPK signaling pathway
    80310 (PDGFD)
   04072 Phospholipase D signaling pathway
    80310 (PDGFD)
   04151 PI3K-Akt signaling pathway
    80310 (PDGFD)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    80310 (PDGFD)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    80310 (PDGFD)
   04540 Gap junction
    80310 (PDGFD)
  Cell motility
   04810 Regulation of actin cytoskeleton
    80310 (PDGFD)
 Human Diseases
  Cancers
   05231 Choline metabolism in cancer
    80310 (PDGFD)
   05218 Melanoma
    80310 (PDGFD)
   05215 Prostate cancer
    80310 (PDGFD)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    80310 (PDGFD)
Cytokines [BR:hsa04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass I
    80310 (PDGFD)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    PDGFRA; platelet-derived growth factor receptor, alpha polypeptide [KO:K04363]
     80310 (PDGFD)
    PDGFRB; platelet-derived growth factor receptor, beta polypeptide [KO:K05089]
     80310 (PDGFD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q9GZP0(Tbio)
UniProt: 
Position
11q22.3
AA seq 370 aa AA seqDB search
MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRDESNHLTDLYRRDETIQVKG
NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS
ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASE
TNWESVTSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMY
LDTPRYRGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQ
RCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERC
DCICSSRPPR
NT seq 1113 nt NT seq  +upstreamnt  +downstreamnt
atgcaccggctcatctttgtctacactctaatctgcgcaaacttttgcagctgtcgggac
acttctgcaaccccgcagagcgcatccatcaaagctttgcgcaacgccaacctcaggcga
gatgagagcaatcacctcacagacttgtaccgaagagatgagaccatccaggtgaaagga
aacggctacgtgcagagtcctagattcccgaacagctaccccaggaacctgctcctgaca
tggcggcttcactctcaggagaatacacggatacagctagtgtttgacaatcagtttgga
ttagaggaagcagaaaatgatatctgtaggtatgattttgtggaagttgaagatatatcc
gaaaccagtaccattattagaggacgatggtgtggacacaaggaagttcctccaaggata
aaatcaagaacgaaccaaattaaaatcacattcaagtccgatgactactttgtggctaaa
cctggattcaagatttattattctttgctggaagatttccaacccgcagcagcttcagag
accaactgggaatctgtcacaagctctatttcaggggtatcctataactctccatcagta
acggatcccactctgattgcggatgctctggacaaaaaaattgcagaatttgatacagtg
gaagatctgctcaagtacttcaatccagagtcatggcaagaagatcttgagaatatgtat
ctggacacccctcggtatcgaggcaggtcataccatgaccggaagtcaaaagttgacctg
gataggctcaatgatgatgccaagcgttacagttgcactcccaggaattactcggtcaat
ataagagaagagctgaagttggccaatgtggtcttctttccacgttgcctcctcgtgcag
cgctgtggaggaaattgtggctgtggaactgtcaactggaggtcctgcacatgcaattca
gggaaaaccgtgaaaaagtatcatgaggtattacagtttgagcctggccacatcaagagg
aggggtagagctaagaccatggctctagttgacatccagttggatcaccatgaacgatgt
gattgtatctgcagctcaagaccacctcgataa

KEGG   Homo sapiens (human): 8074Help
Entry
8074              CDS       T01001                                 

Gene name
FGF23, ADHR, FGFN, HPDR2, HYPF, PHPTC
Definition
(RefSeq) fibroblast growth factor 23
  KO
K22428  
fibroblast growth factor 23
Organism