KEGG T01001: 1508

Homo sapiens (human): 1508

Entry

1508 CDS T01001

Gene name

CTSB, APPS, CPSB

Definition

cathepsin B (EC:3.4.22.1)

Orthology

K01363

cathepsin B [EC:3.4.22.1]

Organism

hsa Homo sapiens (human)

Pathway

hsa04142	Lysosome
hsa04612	Antigen processing and presentation

Disease

H00932

Tropical calcific pancreatitis

Class

Cellular Processes; Transport and catabolism; Lysosome [PATH:hsa04142]
Organismal Systems; Immune system; Antigen processing and presentation [PATH:hsa04612]

SSDB

Motif

Pfam:

Peptidase_C1 Propeptide_C1 Peptidase_C1_2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3CBJ 1CSB 1HUC 3AI8 2IPP 3PBH 3K9M 3CBK 1PBH 2PBH 1GMY

Position

8p22

AA seq 339 aa
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG
TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW
NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI

NT seq 1020 nt +upstreamnt +downstreamnt
atgtggcagctctgggcctccctctgctgcctgctggtgttggccaatgcccggagcagg
ccctctttccatcccctgtcggatgagctggtcaactatgtcaacaaacggaataccacg
tggcaggccgggcacaacttctacaacgtggacatgagctacttgaagaggctatgtggt
accttcctgggtgggcccaagccaccccagagagttatgtttaccgaggacctgaagctg
cctgcaagcttcgatgcacgggaacaatggccacagtgtcccaccatcaaagagatcaga
gaccagggctcctgtggctcctgctgggccttcggggctgtggaagccatctctgaccgg
atctgcatccacaccaatgcgcacgtcagcgtggaggtgtcggcggaggacctgctcaca
tgctgtggcagcatgtgtggggacggctgtaatggtggctatcctgctgaagcttggaac
ttctggacaagaaaaggcctggtttctggtggcctctatgaatcccatgtagggtgcaga
ccgtactccatccctccctgtgagcaccacgtcaacggctcccggcccccatgcacgggg
gagggagatacccccaagtgtagcaagatctgtgagcctggctacagcccgacctacaaa
caggacaagcactacggatacaattcctacagcgtctccaatagcgagaaggacatcatg
gccgagatctacaaaaacggccccgtggagggagctttctctgtgtattcggacttcctg
ctctacaagtcaggagtgtaccaacacgtcaccggagagatgatgggtggccatgccatc
cgcatcctgggctggggagtggagaatggcacaccctactggctggttgccaactcctgg
aacactgactggggtgacaatggcttctttaaaatactcagaggacaggatcactgtgga
atcgaatcagaagtggtggctggaattccacgcaccgatcagtactgggaaaagatctaa

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (14)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (47)   
   RefSeq(nuc) (5)   
   GenBank (21)   
   EMBL (21)   
3D Structure (11)   
   PDB (11)   
Protein domain (3)   
   Pfam (3)   
All databases (96)   

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