KEGG   Homo sapiens (human): 151Help
Entry
151               CDS       T01001                                 

Gene name
ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, FAME2, alpha-2BAR
Definition
(RefSeq) adrenoceptor alpha 2B
  KO
K04139  
adrenergic receptor alpha-2B
Organism
hsa  Homo sapiens (human)
Pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Drug target
Epinephrine [DG:DG00013]: 
Norepinephrine [DG:DG00212]: 
Oxedrine [DG:DG00217]: 
Metaraminol [DG:DG00218]: 
Ephedrine [DG:DG00227]: 
Methyldopa (levorotatory) [DG:DG00248]: 
Clonidine [DG:DG00249]: 
Guanfacine [DG:DG00250]: 
Rilmenidine: 
Phentolamine [DG:DG00280]: 
Tolazoline [DG:DG00281]: 
Phenoxybenzamine [DG:DG00285]: 
Brimonidine [DG:DG00442]: 
Methylergometrine [DG:DG00445]: 
Ergometrine [DG:DG00446]: 
Yohimbin [DG:DG00485]: 
Tizanidine [DG:DG00773]: 
Piribedil: 
Chlorpromazine [DG:DG00867]: 
Levomepromazine [DG:DG00868]: 
Asenapine: 
Dexmedetomidine [DG:DG00926]: 
Mianserin [DG:DG00951]: 
Mirtazapine: 
Lofexidine [DG:DG01001]: 
Pseudoephedrine [DG:DG01042]: 
Dipivefrine [DG:DG01129]: 
Apraclonidine [DG:DG01130]: 
Dapiprazole [DG:DG01140]: 
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04022 cGMP - PKG signaling pathway
    151 (ADRA2B)
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    151 (ADRA2B)
G protein-coupled receptors [BR:hsa04030]
 Class A. Rhodopsin family
  Biogenic amine [Fig]
   Adrenaline [OT]
    151 (ADRA2B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
2q11.1
AA seq 450 aa AA seqDB search
MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRR
AQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSS
LNPVIYTIFNQDFRRAFRRILCRPWTQTAW
NT seq 1353 nt NT seq  +upstreamnt  +downstreamnt
atggaccaccaggacccctactccgtgcaggccacagcggccatagcggcggccatcacc
ttcctcattctctttaccatcttcggcaacgctctggtcatcctggctgtgttgaccagc
cgctcgctgcgcgcccctcagaacctgttcctggtgtcgctggccgccgccgacatcctg
gtggccacgctcatcatccctttctcgctggccaacgagctgctgggctactggtacttc
cggcgcacgtggtgcgaggtgtacctggcgctcgacgtgctcttctgcacctcgtccatc
gtgcacctgtgcgccatcagcctggaccgctactgggccgtgagccgcgcgctggagtac
aactccaagcgcaccccgcgccgcatcaagtgcatcatcctcactgtgtggctcatcgcc
gccgtcatctcgctgccgcccctcatctacaagggcgaccagggcccccagccgcgcggg
cgcccccagtgcaagctcaaccaggaggcctggtacatcctggcctccagcatcggatct
ttctttgctccttgcctcatcatgatccttgtctacctgcgcatctacctgatcgccaaa
cgcagcaaccgcagaggtcccagggccaagggggggcctgggcagggtgagtccaagcag
ccccgacccgaccatggtggggctttggcctcagccaaactgccagccctggcctctgtg
gcttctgccagagaggtcaacggacactcgaagtccactggggagaaggaggagggggag
acccctgaagatactgggacccgggccttgccacccagttgggctgcccttcccaactca
ggccagggccagaaggagggtgtttgtggggcatctccagaggatgaagctgaagaggag
gaagaggaggaggaggaggaggaagagtgtgaaccccaggcagtgccagtgtctccggcc
tcagcttgcagccccccgctgcagcagccacagggctcccgggtgctggccaccctacgt
ggccaggtgctcctgggcaggggcgtgggtgctataggtgggcagtggtggcgtcgacgg
gcgcagctgacccgggagaagcgcttcaccttcgtgctggctgtggtcattggcgttttt
gtgctctgctggttccccttcttcttcagctacagcctgggagccatctgcccgaagcac
tgcaaggtgccccatggcctcttccagttcttcttctggatcggctactgcaacagctca
ctgaaccctgttatctacaccatcttcaaccaggacttccgccgtgccttccggaggatc
ctgtgccgcccgtggacccagacggcctggtga

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