KEGG   Homo sapiens (human): 1514Help
Entry
1514              CDS       T01001                                 

Gene name
CTSL, CATL, CTSL1, MEP
Definition
(RefSeq) cathepsin L (EC:3.4.22.15)
  KO
K01365  
cathepsin L [EC:3.4.22.15]
Organism
hsa  Homo sapiens (human)
Pathway
Lysosome
Phagosome
Apoptosis
Antigen processing and presentation
Proteoglycans in cancer
Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    1514 (CTSL)
   04142 Lysosome
    1514 (CTSL)
  Cell growth and death
   04210 Apoptosis
    1514 (CTSL)
 Organismal Systems
  Immune system
   04612 Antigen processing and presentation
    1514 (CTSL)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    1514 (CTSL)
  Immune diseases
   05323 Rheumatoid arthritis
    1514 (CTSL)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.15  cathepsin L
     1514 (CTSL)
Peptidases [BR:hsa01002]
 Cysteine Peptidases
  Family C1: papain family
   1514 (CTSL)
Chaperones and folding catalysts [BR:hsa03110]
 Intramolecular chaperones
  Papain family
   1514 (CTSL)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Others
  1514 (CTSL)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
9q21.33
AA seq 333 aa AA seqDB search
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
NT seq 1002 nt NT seq  +upstreamnt  +downstreamnt
atgaatcctacactcatccttgctgccttttgcctgggaattgcctcagctactctaaca
tttgatcacagtttagaggcacagtggaccaagtggaaggcgatgcacaacagattatac
ggcatgaatgaagaaggatggaggagagcagtgtgggagaagaacatgaagatgattgaa
ctgcacaatcaggaatacagggaagggaaacacagcttcacaatggccatgaacgccttt
ggagacatgaccagtgaagaattcaggcaggtgatgaatggctttcaaaaccgtaagccc
aggaaggggaaagtgttccaggaacctctgttttatgaggcccccagatctgtggattgg
agagagaaaggctacgtgactcctgtgaagaatcagggtcagtgtggttcttgttgggct
tttagtgctactggtgctcttgaaggacagatgttccggaaaactgggaggcttatctca
ctgagtgagcagaatctggtagactgctctgggcctcaaggcaatgaaggctgcaatggt
ggcctaatggattatgctttccagtatgttcaggataatggaggcctggactctgaggaa
tcctatccatatgaggcaacagaagaatcctgtaagtacaatcccaagtattctgttgct
aatgacaccggctttgtggacatccctaagcaggagaaggccctgatgaaggcagttgca
actgtggggcccatttctgttgctattgatgcaggtcatgagtccttcctgttctataaa
gaaggcatttattttgagccagactgtagcagtgaagacatggatcatggtgtgctggtg
gttggctacggatttgaaagcacagaatcagataacaataaatattggctggtgaagaac
agctggggtgaagaatggggcatgggtggctacgtaaagatggccaaagaccggagaaac
cattgtggaattgcctcagcagccagctaccccactgtgtga

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