KEGG   Homo sapiens (human): 152Help
Entry
152               CDS       T01001                                 

Gene name
ADRA2C, ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR
Definition
(RefSeq) adrenoceptor alpha 2C
  KO
K04140  
adrenergic receptor alpha-2C
Organism
hsa  Homo sapiens (human)
Pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Drug target
Apraclonidine (DG01130): 
Aptazapine maleate: 
Arotinolol (DG01303): 
Asenapine: 
Atipamezole: 
Brimonidine (DG00442): 
Chlorpromazine (DG00867): 
Clonidine (DG00249): 
Clozapine: 
Dapiprazole (DG01140): 
Delequamine hydrochloride: 
Detomidine (DG01318): 
Dexmedetomidine (DG00926): 
Dihydroergocristine (DG00284): 
Dipivefrine (DG01129): 
Domazoline fumarate: 
Droxidopa: 
Ephedrine (DG00227): 
Epinephrine (DG00013): 
Epinephryl borate: 
Ergometrine (DG00446): 
Etilefrine (DG00210): 
Fadolmidine hydrochloride: 
Fluparoxan hydrochloride: 
Guanabenz (DG01230): 
Guanadrel: 
Guanadrel sulfate: 
Guanfacine (DG00250): 
Levomepromazine (DG00868): 
Levonordefrin: 
Medetomidine (DG01320): 
Metaraminol (DG00218): 
Methyldopa (levorotatory) (DG00248): 
Methylephedrine (DG01229): 
Methylergometrine (DG00445): 
Metizoline: 
Mianserin (DG00951): 
Mirtazapine: 
Norepinephrine (DG00212): 
Octodrine: 
Oxedrine (DG00217): 
Phenoxybenzamine (DG00285): 
Phentolamine (DG00280): 
Phenylpropanolamine (DG01041): 
Piribedil: 
Propylhexedrine (DG01919): 
Pseudoephedrine (DG01042): 
Quetiapine (DG00899): 
Racephedrine Hydrochloride: 
Rilmenidine: 
Romifidine: 
Setiptiline (DG01231): 
Sunepitron hydrochloride: 
Tizanidine (DG00773): 
Tolazoline (DG00281): 
Xylazine (DG01321): 
Yohimbin (DG00485): 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04022 cGMP - PKG signaling pathway
    152 (ADRA2C)
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    152 (ADRA2C)
G protein-coupled receptors [BR:hsa04030]
 Class A. Rhodopsin family
  Biogenic amine [Fig]
   Adrenaline [OT]
    152 (ADRA2C)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P18825(Tclin)
UniProt: 
Position
4p16.3
AA seq 462 aa AA seqDB search
MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA
LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRR
RRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFK
FFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
NT seq 1389 nt NT seq  +upstreamnt  +downstreamnt
atggcgtccccggcgctggcggcggcgctggcggtggcggcagcggcgggccccaatgcg
agcggcgcgggcgagaggggcagcggcggggttgccaatgcctcgggggcttcctggggg
ccgccgcgcggccagtactcggcgggcgcggtggcagggctggctgccgtggtgggcttc
ctcatcgtcttcaccgtggtgggcaacgtgctggtggtgatcgccgtgctgaccagccgg
gcgctgcgcgcgccacagaacctcttcctggtgtcgctggcctcggccgacatcctggtg
gccacgctggtcatgcccttctcgttggccaacgagctcatggcctactggtacttcggg
caggtgtggtgcggcgtgtacctggcgctcgatgtgctgttttgcacctcgtcgatcgtg
catctgtgtgccatcagcctggaccgctactggtcggtgacgcaggccgtcgagtacaac
ctgaagcgcacaccacgccgcgtcaaggccaccatcgtggccgtgtggctcatctcggcc
gtcatctccttcccgccgctggtctcgctctaccgccagcccgacggcgccgcctacccg
cagtgcggcctcaacgacgagacctggtacatcctgtcctcctgcatcggctccttcttc
gcgccctgcctcatcatgggcctggtctacgcgcgcatctaccgagtggccaagctgcgc
acgcgcacgctcagcgagaagcgcgcccccgtgggccccgacggtgcgtccccgactacc
gaaaacgggctgggcgcggcggcaggcgcaggcgagaacgggcactgcgcgcccccgccc
gccgacgtggagccggacgagagcagcgcagcggccgagaggcggcggcgccggggcgcg
ttgcggcggggcgggcggcggcgagcgggcgcggaggggggcgcgggcggtgcggacggg
cagggggcggggccgggggcggctgagtcgggggcgctgaccgcctccaggtccccgggg
cccggtggccgcctgtcgcgcgccagctcgcgctccgtcgagttcttcctgtcgcgccgg
cgccgggcgcgcagcagcgtgtgccgccgcaaggtggcccaggcgcgcgagaagcgcttc
acctttgtgctggctgtggtcatgggcgtgttcgtgctctgctggttccccttcttcttc
agctacagcctgtacggcatctgccgcgaggcctgccaggtgcccggcccgctcttcaag
ttcttcttctggatcggctactgcaacagctcgctcaacccggtcatctacacggtcttc
aaccaggatttccggcgatcctttaagcacatcctcttccgacggaggagaaggggcttc
aggcagtga

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