KEGG T01001: 1520

Homo sapiens (human): 1520

Entry

1520 CDS T01001

Gene name

CTSS

Definition

cathepsin S (EC:3.4.22.27)

Orthology

K01368

cathepsin S [EC:3.4.22.27]

Organism

hsa Homo sapiens (human)

Pathway

hsa04142	Lysosome
hsa04145	Phagosome
hsa04612	Antigen processing and presentation
hsa05152	Tuberculosis

Class

Cellular Processes; Transport and catabolism; Phagosome [PATH:hsa04145]
Cellular Processes; Transport and catabolism; Lysosome [PATH:hsa04142]
Organismal Systems; Immune system; Antigen processing and presentation [PATH:hsa04612]
Human Diseases; Infectious diseases; Tuberculosis [PATH:hsa05152]

SSDB

Motif

Pfam:

Peptidase_C1 Inhibitor_I29 Peptidase_C1_2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3OVX 2H7J 2HHN 3N3G 2OP3 2FRQ 2FQ9 2FT2 3MPF 2HH5 1NQC 3N4C 2HXZ 2FRA 2F1G 1MS6 2FUD 2R9M 2R9N 2R9O 2G7Y 1NPZ 3KWN 3IEJ 2FYE 3MPE 2G6D 2C0Y 1GLO

Position

1q21

AA seq 281 aa
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDC
STEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTEL
PYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNG
KEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI

NT seq 846 nt +upstreamnt +downstreamnt
atgaaacggctggtttgtgtgctcttggtgtgctcctctgcagtggcacagttgcataaa
gatcctaccctggatcaccactggcatctctggaagaaaacctatggcaaacaatacaag
gaaaagaatgaagaagcagtacgacgtctcatctgggaaaagaatctaaagtttgtgatg
cttcacaacctggagcattcaatgggaatgcactcatacgatctgggcatgaaccacctg
ggagacatgggttcttgtggtgcttgctgggctttcagtgctgtgggggccctggaagca
cagctgaagctgaaaacaggaaagctggtgtctctcagtgcccagaacctggtggattgc
tcaactgaaaaatatggaaacaaaggctgcaatggtggcttcatgacaacggctttccag
tacatcattgataacaagggcatcgactcagacgcttcctatccctacaaagccatggat
cagaaatgtcaatatgactcaaaatatcgtgctgccacatgttcaaagtacactgaactt
ccttatggcagagaagatgtcctgaaagaagctgtggccaataaaggcccagtgtctgtt
ggtgtagatgcgcgtcatccttctttcttcctctacagaagtggtgtctactatgaacca
tcctgtactcagaatgtgaatcatggtgtacttgtggttggctatggtgatcttaatggg
aaagaatactggcttgtgaaaaacagctggggccacaactttggtgaagaaggatatatt
cggatggcaagaaataaaggaaatcattgtgggattgctagctttccctcttacccagaa
atctag

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (22)   
   RefSeq(nuc) (2)   
   GenBank (10)   
   EMBL (10)   
3D Structure (29)   
   PDB (29)   
Protein domain (3)   
   Pfam (3)   
All databases (80)   

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