KEGG T01001: 1548

Homo sapiens (human): 1548

Entry

1548 CDS T01001

Gene name

CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB

Definition

cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)

Orthology

K07411

cytochrome P450, family 2, subfamily A [EC:1.14.14.1]

Organism

hsa Homo sapiens (human)

Pathway

hsa00232	Caffeine metabolism
hsa00830	Retinol metabolism
hsa00980	Metabolism of xenobiotics by cytochrome P450
hsa00982	Drug metabolism - cytochrome P450
hsa00983	Drug metabolism - other enzymes
hsa01100	Metabolic pathways
hsa05204	Chemical carcinogenesis

Class

Metabolism; Metabolism of cofactors and vitamins; Retinol metabolism [PATH:hsa00830]
Metabolism; Biosynthesis of other secondary metabolites; Caffeine metabolism [PATH:hsa00232]
Metabolism; Xenobiotics biodegradation and metabolism; Metabolism of xenobiotics by cytochrome P450 [PATH:hsa00980]
Metabolism; Xenobiotics biodegradation and metabolism; Drug metabolism - cytochrome P450 [PATH:hsa00982]
Metabolism; Xenobiotics biodegradation and metabolism; Drug metabolism - other enzymes [PATH:hsa00983]
Human Diseases; Cancers; Chemical carcinogenesis [PATH:hsa05204]

SSDB

Motif

Pfam:

p450

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2FDV 2FDU 1Z10 2PG5 2FDY 2FDW 1Z11 3T3Q 3EBS 4EJJ 3T3R 2PG6 2PG7

Position

19q13.2

AA seq 494 aa
MLASGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMK
ISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSN
GERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSN
VISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQL
LQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFI
GGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQ
RFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEK
GQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGF
ATIPRNYTMSFLPR

NT seq 1485 nt +upstreamnt +downstreamnt
atgctggcctcagggatgcttctggtggccttgctggtctgcctgactgtaatggtcttg
atgtctgtttggcagcagaggaagagcaaggggaagctgcctccgggacccaccccattg
cccttcattggaaactacctgcagctgaacacagagcagatgtacaactccctcatgaag
atcagtgagcgctatggccccgtgttcaccattcacttggggccccggcgggtcgtggtg
ctgtgtggacatgatgccgtcagggaggctctggtggaccaggctgaggagttcagcggg
cgaggcgagcaagccaccttcgactgggtcttcaaaggctatggcgtggtattcagcaac
ggggagcgcgccaagcagctccggcgcttctccatcgccaccctgcgggacttcggggtg
ggcaagcgaggcatcgaggagcgcatccaggaggaggcgggcttcctcatcgacgccctc
cggggcactggcggcgccaatatcgatcccaccttcttcctgagccgcacagtctccaat
gtcatcagctccattgtctttggggaccgctttgactataaggacaaagagttcctgtca
ctgttgcgcatgatgctaggaatcttccagttcacgtcaacctccacggggcagctctat
gagatgttctcttcggtgatgaaacacctgccaggaccacagcaacaggcctttcagttg
ctgcaagggctggaggacttcatagccaagaaggtggagcacaaccagcgcacgctggat
cccaattccccacgggacttcattgactcctttctcatccgcatgcaggaggaggagaag
aaccccaacacggagttctacttgaaaaacctggtgatgaccacgttgaacctcttcatt
gggggcaccgagaccgtcagcaccaccctgcgctatggcttcttgctgctcatgaagcac
ccagaggtggaggccaaggtccatgaggagattgacagagtgatcggcaagaaccggcag
cccaagtttgaggaccgggccaagatgccctacatggaggcagtgatccacgagatccaa
agatttggagacgtgatccccatgagtttggcccgcagagtcaaaaaggacaccaagttt
cgggatttcttcctccctaagggcaccgaagtgtaccctatgctgggctctgtgctgaga
gaccccagtttcttctccaacccccaggacttcaatccccagcacttcctgaatgagaag
gggcagtttaagaagagtgatgcttttgtgcccttttccatcggaaagcggaactgtttc
ggagaaggcctggccagaatggagctctttctcttcttcaccaccgtcatgcagaacttc
cgcctcaagtcctcccagtcacctaaggacattgacgtgtcccccaaacacgtgggcttt
gccacgatcccacgaaactacaccatgagcttcctgccccgctga

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Disease (4)   
   OMIM (4)   
Drug (10)   
   KEGG DRUG (10)   
Chemical substance (27)   
   KEGG COMPOUND (27)   
Chemical reaction (13)   
   KEGG ENZYME (1)   
   KEGG REACTION (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (11)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   NAGAHAMA-H (4)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (29)   
   RefSeq(nuc) (1)   
   GenBank (14)   
   EMBL (14)   
3D Structure (13)   
   PDB (13)   
Protein domain (1)   
   Pfam (1)   
All databases (133)   

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